Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,982 recruiting studies in this area right now.
By phase
- Not applicable7,962
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke844
- Heart Failure566
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California465
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois118
- Texas118
Recruiting studies9,979 total
- NCT04129021Recruiting
Eye imaging test with fast detailed scans
This trial studies whether a new, very high-resolution and high-speed eye scan can be used for people with eye problems or for healthy volunteers. It may help doctors better “see” eye structures more clearly to guide care.
ParisAges 18 years+ - NCT04133272Recruiting
Registry for Ehlers-Danlos syndrome patients and pregnancies
This study is a registry that collects information about people with Ehlers-Danlos syndrome, including unborn babies diagnosed before birth. It may help researchers learn more about the condition and improve care over time.
Bologna, Emilia-RomagnaAges Any age - NCT04139616Recruiting
Testing a planned heart rhythm plan after aortic valve replacement
This study tests an algorithm—a step-by-step plan—for how doctors manage abnormal heart rhythms after transcatheter aortic valve replacement (TAVR). It may help guide safer, more consistent care in the weeks after the procedure.
Québec, QuebecAges 18 years+ - NCT04141020RecruitingPhase 2
Sirolimus study for unruptured brain aneurysms after surgery
This Phase 2 study tests whether sirolimus, a medicine that changes immune and growth signals, can change what’s happening inside the tissue of unruptured brain aneurysms after a procedure. Researchers hope these molecular changes may help understand how to improve aneurysm outcomes.
Miami, FloridaAges 18 years+ - NCT04142866Recruiting
Brain stimulation plus language practice for chronic aphasia
This study tests whether mild brain stimulation (tDCS) combined with language exercises can improve communication after a stroke. It also includes healthy volunteers to help compare brain and language task results.
New York, New YorkAges 21–80 - NCT04145024Recruiting
Pulmonary hypertension registry and blood sample biobank
This study keeps a health registry and biobank for people diagnosed with pulmonary hypertension using a specific heart test. It helps researchers better understand the condition and may improve future care.
GiessenAges Any age - NCT04149743Recruiting
Testing a heart-watching patch to track short-term heart failure outcomes
This trial checks whether a medical patch called HEMOTAG can help doctors predict or track how patients do shortly after a hospital stay for worsening heart failure. It may help improve early monitoring and treatment decisions after discharge.
Weston, FloridaAges 22 years+ - NCT04155606Recruiting
Care plan for brain aneurysms after confirmation
This study looks at a comprehensive treatment approach for people who have a confirmed brain (intracranial) subarachnoid aneurysm. It may help by comparing or improving how aneurysms are managed to reduce future bleeding risk.
Edmonton, AlbertaAges 18 years+ - NCT04153292Recruiting
Testing a valve procedure for severe mitral regurgitation
This trial studies a minimally invasive mitral valve repair/replacement approach for people with severe mitral regurgitation (leaky mitral valve) who are not good candidates for standard surgery or catheter options. It may help improve symptoms by treating the leaky valve when other treatments aren’t suitable.
Huntsville, AlabamaAges 18 years+ - NCT04157179Recruiting
MRI study of brain oxygen use in children and adults
This study uses an MRI scan to measure how your brain uses oxygen. It includes healthy participants and people with sickle cell disease or who previously needed ECMO, which may help researchers understand brain oxygen problems and how to monitor them.
St Louis, MissouriAges 3–50 - NCT04158479Recruiting
Registry for people on ECMO life support
This registry collects information about people who are placed on ECMO, a heart-lung machine used to support breathing and/or circulation. It may help doctors better understand who benefits and how to manage ECMO in the future.
Beijing, Beijing MunicipalityAges Any age - NCT04160533Recruiting
Registry for people diagnosed with high blood pressure
This registry collects information from people who have been diagnosed with high blood pressure. It may help researchers better understand who has it and how it’s managed in real life.
Moscow, Moscow OblastAges 18–99 - NCT04162353RecruitingPhase 1
CAR cell therapy trial for multiple myeloma and related cancers
This early-phase (Phase 1) trial tests a lab-made immune-cell treatment that targets two markers, BCMA and CD19, in people whose cancer has not responded to standard options. It’s meant to see if the treatment is safe and how well it can work in these cancers.
Shenzhen, GuangdongAges Any age - NCT04162171Recruiting
SBRT treatment study for steady heart rhythm VT
This study looks at using SBRT (high-precision radiation) to treat a dangerous, steady heart rhythm called monomorphic VT. It is meant for people who keep having VT even after prior ablation attempts and after trying a class III “rhythm-stabilizing” medicine.
Halifax, Nova ScotiaAges Any age - NCT04162444Recruiting
Aortic valve reconstruction study for children
This trial studies a surgery approach to help fix a narrowed or leaking aortic valve in children. It aims to see how well the reconstructed valve works and how it affects the child’s heart function over time.
MoscowAges 4 weeks–12 years - NCT04164641Recruiting
Test software-guided walking analysis to help prevent foot ulcers
This study checks whether a computer system that analyzes your walking can help change gait (how you walk) to reduce the chance of diabetic foot ulcers coming back or leading to amputation. It is meant for adults who have had a healed diabetic foot ulcer before.
Baltimore, MarylandAges 18–90 - NCT04167033Recruiting
Checking heart rhythm timing in women with premature ovarian insufficiency
This study measures how quickly the heart “recharges” between beats (often shown as QT timing). It compares women with premature ovarian insufficiency to healthy women to understand whether ovarian insufficiency is linked to heart rhythm differences.
BordeauxAges 18–40 - NCT04166825Recruiting
Study how egg-stimulation blood clots form in infertility
This study looks at how your blood clots (and clotting proteins) behave around ovarian stimulation for infertility care. It may help researchers understand clot-related risks and improve how treatment is monitored.
Krakow, MałopolskaAges 18–40 - NCT04171856Recruiting
Robotic training to improve movement after stroke
This study tests a robotic rehabilitation program to help improve arm movement after an acute or chronic stroke (and separately studies people with transient global amnesia). It may help by measuring how well patients can learn and control movement during repeated robot-guided sessions.
Yvoir, NamurAges 18–90 - NCT04175691Recruiting
Study blood RNA markers after sudden ischemic stroke
This trial looks at blood “RNA markers” (molecules that may reflect brain injury) in people who have had a new ischemic stroke. It may help doctors understand what’s happening in the body soon after stroke and possibly guide future care.
Nanjing, JiangsuAges 18 years+ - NCT04178434Recruiting
Online therapy for stress and anxiety after heart pain without blockages
This trial studies whether an internet-based therapy program can reduce stress and anxiety in people who may have heart-related conditions like MINOCA or takotsubo syndrome, but without significant coronary artery blockages. If you fit the mood and heart criteria, the program may help you feel calmer and improve day-to-day wellbeing.
StockholmAges 35–79 - NCT04182087Recruiting
Testing thinking skills after a localized brain injury
This trial studies how your thinking and memory abilities work after a single, localized brain injury seen on MRI. It involves cognitive (thinking) tasks to assess changes and may help researchers understand brain function after injury.
GrenobleAges 18–70 - NCT04183426Recruiting
Check heart risk tests before planned AAA repair
This study uses a hand/eye pressure test (tonometry) and an ultrasound scan (duplex ultrasound) to see if they can predict future heart or blood vessel events in people with an abdominal aortic aneurysm (AAA) who are planning elective surgery. It may help doctors choose the safest follow-up and treatments for you after repair.
Nijmegen, GelderlandAges 18 years+ - NCT04183660Recruiting
MOBYBOX monitoring study for temporary heart-lung support
This is a post-market “real-world” monitoring study for a heart-lung machine (extracorporeal cardiopulmonary support/ECMO) used during very serious heart and/or lung failure. It aims to track safety and performance in patients who need rescue breathing or circulation support.
Hanover, Lower SaxonyAges 18–80
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,982 recruiting cardiology studies from the U.S. registry right now, out of 15,268 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.