Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT04939805Recruiting
Blood-cleaning treatment after first heart attack
This trial tests whether a blood-cleaning procedure called CRP apheresis, given after a first heart attack, can improve recovery when a heart-attack blood marker (CRP) is high. It’s aimed at people whose heart attack is treated quickly with a procedure to open blocked arteries, and who are well enough for heart MRI scans.
GrazAges 18–85 - NCT04942041Recruiting
Thrombectomy for large stroke blockages at low-volume centers
This study tests whether using a procedure called mechanical thrombectomy at smaller stroke centers can improve outcomes after a large-vessel stroke. It may help people who have a major artery blockage get timely treatment, with measured effects on complications and survival.
Kristiansand, AgderAges 18–100 - NCT04943926Recruiting
Diet changes to help put type 2 diabetes into remission
This study tests whether specific dietary strategies can help people with type 2 diabetes reach remission (better blood sugar without ongoing high medication needs). You may be a good candidate if your diabetes is relatively recent, your weight is above a certain threshold, and your heart and other health conditions are stable.
Bergen, VestlandAges 24–70 - NCT04945174Recruiting
Stroke prevention program with exercise and education
This trial tests a structured “stroke school” program that includes supervised physical activity, education, and follow-up coaching to help reduce future stroke and heart problems. It may help people with minor stroke or a TIA who don’t need rehabilitation but do need safer ways to be more active.
Copenhagen, HerlevAges 18 years+ - NCT04945603Recruiting
Study for poor-grade brain bleed from a ruptured aneurysm
This trial is enrolling people who come to the emergency room with a serious brain bleed caused by a ruptured brain aneurysm. It aims to test care strategies for patients with poor-grade injuries, who may have worse outcomes than typical cases.
BergamoAges 18 years+ - NCT04947618Recruiting
Lymphoma management study at Nimes Hospital (1999-2018)
This trial looks back at how patients with lymphoma were treated at Nimes University Hospital between 1999 and 2018. It aims to better understand the disease and improve care by studying stored tumor samples.
Nîmes, GardAges 15 years+ - NCT04947657Recruiting
Atrial fibrillation blood and heart scan pilot during ablation
This study looks at blood-related “clotting” signs and heart scan results in people with atrial fibrillation (AF) who are getting a catheter ablation. It may help doctors better understand AF and choose treatments more precisely.
New Orleans, LouisianaAges 18–120 - NCT04948658Recruiting
Freezing ovarian tissue to protect future fertility
This study looks at storing ovarian (ovary) tissue by freezing it for people at higher risk of losing fertility. It may help preserve options for having biological children later, especially for certain genetic conditions, cancer-related risks, or planned gonad removal.
Bethesda, MarylandAges 2–35 - NCT04950218Recruiting
Study risks of heart problems in people with psoriasis
This study asks adults with psoriasis about factors that may be linked to heart problems. It aims to better understand who is at higher risk, which could help guide future prevention and care.
Hellerup, CopenhagneAges 18 years+ - NCT04956185Recruiting
Collecting hospital data from people with stroke
This study collects information from people admitted to the stroke care team or neurology during their hospital stay. It may help improve stroke care by understanding patient conditions and hospital experiences.
Ghent, FlandersAges Any age - NCT04962295Recruiting
Brain MRI study for small blood vessel changes
This study builds a brain imaging biobank for people with “small blood vessel disease” seen on MRI. Your MRI results can help researchers better understand these changes and track new events over time.
BeijingAges 18 years+ - NCT04962646Recruiting
Breathing extra carbon dioxide during surgery to prevent brain injury
This trial tests whether giving extra carbon dioxide during surgery can reduce the chance of new brain or nervous system injury after surgery for a sudden, life-threatening tear in the big artery (type A aortic dissection). It may help by protecting the brain while the surgical team repairs the artery.
LundAges 18 years+ - NCT04962711Recruiting
Risk-guided plan to prevent heart failure after cancer treatment
This trial tests whether a personalized, risk-based heart care plan can help prevent heart failure in people who had certain cancer treatments. It focuses on monitoring and guiding treatment, using heart ultrasound results and other health factors.
Melbourne, VictoriaAges 40–85 - NCT04964765Recruiting
3D heart mapping after early irregular heartbeat after surgery
This study uses 3D heart mapping to understand a specific kind of irregular heartbeat that can happen soon after cardiac surgery. It may help doctors better recognize what’s happening in the heart during the early recovery period.
Sankt PöltenAges 18 years+ - NCT04968509RecruitingPhase 3
PCSK9 shots for calcified aortic valve narrowing
This study tests whether adding PCSK9 inhibitor injections (to statin treatment) can slow or improve calcific aortic valve stenosis, a condition where the heart’s aortic valve becomes stiff and narrowed. It’s aimed at adults with mild-to-moderate disease or certain people with severe disease but no symptoms.
Beijing, Beijing MunicipalityAges 18 years+ - NCT04970888Recruiting
Exercise program to improve thinking and brain blood flow in heart failure
This trial tests whether doing a combined mental (cognitive) and physical exercise program can improve thinking and how well blood flows to the brain in people with chronic heart failure. It may help by strengthening both brain function and physical capacity while your heart condition stays stable.
Montreal, QuebecAges 50 years+ - NCT04970459Recruiting
Collecting samples for Marfan and related conditions
This study collects biological samples and related health information for people with Marfan syndrome or similar inherited conditions. It helps researchers better understand these conditions and may lead to improved care for patients in the future.
ToulouseAges 3–99 - NCT04972526Recruiting
Registry for adult patients who get an ultrasound heart scan in ICU
This study is a registry, meaning it collects information from adult patients who—during routine emergency care in the ICU—receive a focused ultrasound of the heart (a test called TEE). It helps doctors learn how this test is used and what outcomes follow, with no extra treatment required.
Philadelphia, PennsylvaniaAges 18 years+ - NCT04971564Recruiting
Blood inflammation test study in sudden brain oxygen loss
This trial looks at blood “inflammation-related” biomarkers to understand what happens early after certain sudden brain events. It may help doctors predict outcomes and tailor treatment for people like those with stroke types that sometimes need a clot-removal procedure.
Paris, Île-de-France RegionAges 18 years+ - NCT04971720RecruitingPhase 2/Phase 3
Personalized blood pressure timing therapy for some adults
This trial tests whether timing blood pressure medications (based on your natural daily body rhythms) can improve blood pressure control. It’s designed for adults with moderately high blood pressure and focuses on who may benefit from a more precise schedule.
Birmingham, AlabamaAges 18 years+ - NCT04974138RecruitingPhase 4
Preventing first stroke in people with high-risk blood pressure
This trial tests whether a study medicine regimen can help prevent a first stroke in people with hard-to-control “high homocysteine” risk factors linked to a specific gene type. You may qualify if you have certain blood pressure levels, a specific MTHFR gene result, and related blood test findings.
Bengbu, AnhuiAges 45–74 - NCT04973397Recruiting
Preventing vascular complications during same-day non-heart surgery
This study looks at ways to reduce blood vessel–related problems (like stroke or heart strain) around the time of planned same-day, non-heart surgery. If you qualify, you may be asked to take part in a specific prevention plan during and around your operation.
Winston-Salem, North CarolinaAges 45 years+ - NCT04973579Recruiting
Stent plus heart surgery for high risk carotid patients
This trial looks at whether doing carotid artery stenting at the same time as heart surgery is safe and effective for people at high risk of stroke around the time of surgery. It targets people with significant carotid narrowing who also need heart surgery for specific heart problems.
KrakowAges 18 years+ - NCT04974151RecruitingPhase 4
Prevention trial for stroke risk in people with high blood pressure
This trial tests an approach to prevent first-time stroke and heart problems in people with high blood pressure who also have a specific genetic test result (MTHFR 677 TT). It may help by lowering risk before a first stroke happens.
Bengbu, AnhuiAges 45–74
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.