Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,613 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3438
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke796
- Heart Failure535
- Hypertension389
- Cardiovascular Diseases374
- Coronary Artery Disease362
- Multiple Myeloma328
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona182
- Massachusetts174
- New York166
- Florida141
- Texas122
- Maryland118
- Minnesota118
- Illinois111
Recruiting studies9,613 total
- NCT07403630Recruiting
Tumor chemogenomic profiler for cancer patients of all ages
This trial uses a new testing platform to analyze the genes and proteins in your tumor, aiming to find the most effective treatments for people with cancer that has come back, is not responding to treatment, or has spread. It is designed for both children and adults with any type of blood cancer or solid tumor.
Palermo, PalermoAges 1 year+ - NCT07405242Recruiting
Treatment for retrograde aortic dissection with a stent graft
This trial tests a stent-graft procedure for a specific type of aortic dissection where the tear starts in the arch or descending aorta and extends backward into the ascending aorta. It is for patients who are not good candidates for open surgery.
Shanghai, Shanghai MunicipalityAges 65 years+ - NCT07398911Enrolling by invitation
3D simulated TAVR for aortic valve leak
This trial tests whether a 3D computer simulation can help guide a less invasive procedure (TAVR) to replace a leaky aortic valve. It may be an option for people with severe aortic regurgitation who are at least 65 years old.
Xi’an, ShanxiAges 65 years+ - NCT07405671RecruitingPhase 4
Flecainide safety for heart patients with atrial fibrillation
This trial tests a heart rhythm drug called flecainide to see if it is safe for people who have both atrial fibrillation (an irregular heartbeat) and coronary artery disease (narrowed heart blood vessels). Participation could help doctors decide if this drug is a good treatment option for you.
AalstAges 18 years+ - NCT07399587RecruitingPhase 2/Phase 3
Optimizing heart failure treatment with two devices
This study tests whether using two implanted devices (CardioMems and BaroStim) can improve heart function and symptoms in people with advanced heart failure. It aims to help patients who are already on standard medications get even better results.
Riverhead, New YorkAges 18–80 - NCT07400510Enrolling by invitation
Ultrasound for DVT diagnosis and treatment
This trial uses a bedside ultrasound to quickly diagnose deep vein thrombosis (DVT) and help guide treatment. It may help patients who have symptoms like leg swelling or pain.
Hershey, PennsylvaniaAges 18 years+ - NCT07405359Recruiting
Comparing ablation methods for persistent atrial fibrillation
This trial tests a newer, possibly safer way to treat persistent atrial fibrillation using pulsed field ablation. It compares standard vein isolation alone to adding extra ablation spots to improve success.
San Francisco, CaliforniaAges 18 years+ - NCT07404774Recruiting
stitch and laser treatment for hemorrhoids
This trial is testing a combined treatment for hemorrhoids that are causing symptoms. It uses a technique to stitch the hemorrhoid tissue back in place (suture mucopexy) plus a laser to shrink blood vessels. The goal is to see if this approach works well for people with grades II, III, or IV hemorrhoids, even if they've had other treatments before.
AthensAges 18 years+ - NCT07400042Recruiting
Peripheral vein pressure test for heart failure patients
This study tests if measuring pressure from a vein in the arm can help guide treatment for people hospitalized with worsening heart failure. It aims to understand if this simple procedure could replace or reduce the need for more invasive monitoring.
Milwaukee, WisconsinAges 18 years+ - NCT07398508RecruitingPhase 1/Phase 2
Northera for dizziness and diarrhea in Menkes disease survivors
This trial tests if the drug Northera (droxidopa) can help children with Menkes disease who have dizziness when standing or chronic diarrhea. It aims to improve these symptoms by supporting blood pressure and bowel function.
New York, New YorkAges 7–17 - NCT06323538Recruiting
Plant-based diets and health (COPLANT)
This study looks at how different plant-based diets affect your health. Researchers will collect information through questionnaires and blood samples to understand the benefits of eating more plants.
ViennaAges 18–69 - NCT06338293RecruitingPhase 4
Inclisiran plus statins for fragile heart plaque
This trial tests if adding inclisiran to your current statin can reduce dangerous, rupture-prone plaque in your heart arteries. It may help if you have a moderate blockage with thin-cap plaque and your LDL cholesterol stays high despite statins.
Nanjing, JiangsuAges 18–80 - NCT06789978Recruiting
Quick ECPR for cardiac arrest in Prague
This study tests a rapid way to give life support using a heart-lung bypass machine (ECPR) to people experiencing a sudden cardiac arrest that doesn't stop with defibrillators or standard CPR. The goal is to start this treatment within 20 minutes of the emergency call, which may improve chances of survival.
Prague, CzechiaAges 18–70 - NCT06688409Recruiting
Testing home blood pressure devices sold online
This study tests how accurate home blood pressure monitors sold online are. You may be eligible if you are already scheduled for a 24-hour blood pressure test (ABPM) and do not have certain health conditions.
Montreal, QuebecAges 18 years+ - NCT06826534Recruiting
At-home heart rehab for teens with heart failure risk
This study tests if a home-based exercise program using a Fitbit can help teens who had chemotherapy improve their heart and lung fitness. You would exercise at home, track your activity, and have monthly virtual check-ins for 6 months.
Los Angeles, CaliforniaAges birth–21 years - NCT06827314Recruiting
Treating cardiogenic shock with drug and mechanical support
This trial is testing different approaches (medications and mechanical support) to help people with acute heart failure and cardiogenic shock (a sudden drop in the heart's pumping ability). It looks at how well these treatments work in a network of hospitals to improve outcomes.
Bologna, BolognaAges 18 years+ - NCT06827301Recruiting
Vagus nerve stimulation for swallowing problems after stroke
This trial tests a non-invasive device that stimulates a nerve in the ear to help improve swallowing after a recent stroke. It may be an option if you have moderate swallowing difficulties diagnosed within the first week after your stroke.
Roma, RMAges 18 years+ - NCT06827652Recruiting
Triple-A Barcelona: A study for abdominal aortic aneurysms
This study is testing a new approach to manage abdominal aortic aneurysms (bulges in the main belly artery). It is for people whose aneurysm is larger than 30 mm but does not have certain rare features that require different care.
Barcelona, CataloniaAges 18 years+ - NCT06826872RecruitingPhase 2
Testing SPC1001 for essential hypertension
This trial tests an oral medication called SPC1001 to see if it can safely lower blood pressure in people with essential hypertension (high blood pressure not caused by another condition). It may help if you have mild to moderate high blood pressure.
SeoulAges 19–75 - NCT04782232Recruiting
Study of a new blood tube for heart pump patients
This registry study checks whether a new venous blood tube used with a heart pump is safe and practical for people whose right heart is failing and who may need a heart transplant. If you qualify, your care team would monitor how the device works over time.
MunichAges Any age - NCT06749223Recruiting
Testing a D-dimer blood test for blood clots
This study is testing a new D-dimer blood test (AQT90 FLEX) to see how well it detects blood clots in people who have symptoms but a low to moderate risk. If you join, this test may help rule out dangerous clots more quickly.
ViborgAges 18 years+ - NCT06443008Recruiting
Biofeedback training for arm function after stroke
This study tests whether a special feedback device that detects muscle signals can help improve arm and hand movement after a stroke. It is designed for people aged 65 and older.
Yiwu, ZhejiangAges 65–80 - NCT06535503Recruiting
Heart attack with shock: Study of patient outcomes in Abu Dhabi
This study looks at the medical records of people who had a severe heart attack (STEMI) that caused cardiogenic shock. Researchers want to understand how these patients did during their hospital stay to improve care in the future.
Abu Dhabi, Abu Dhabi EmirateAges 18 years+ - NCT06741475Recruiting
Caregiver help strategy training for stroke recovery
This study tests a caregiver-assisted strategy training program for people recovering from a stroke. It aims to see if having a healthy caregiver help with daily tasks can improve recovery for those who have limited rehabilitation.
New Taipei CityAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,613 recruiting cardiology studies from the U.S. registry right now, out of 14,690 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.