Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,613 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3438
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke796
- Heart Failure535
- Hypertension389
- Cardiovascular Diseases374
- Coronary Artery Disease362
- Multiple Myeloma328
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona182
- Massachusetts174
- New York166
- Florida141
- Texas122
- Maryland118
- Minnesota118
- Illinois111
Recruiting studies9,613 total
- NCT07395544Enrolling by invitation
Gait training for stroke patients using a stationary trainer
This trial tests a stationary trainer to help people who have had a stroke improve their walking. It focuses on those who can already walk on their own but need to improve their gait and coordination.
Taipei, Beitou Dist.Ages 20 years+ - NCT07394959Recruiting
Guided hydration to protect kidneys in elderly heart patients
This trial tests a new way to manage fluids during heart procedures to prevent kidney injury. It uses a special vest that measures lung fluid to guide how much hydration you get.
Beijing, Beijing MunicipalityAges 60 years+ - NCT07392749Recruiting
Diaphragm pacing via vein during CRT implant
This trial is testing a new way to pace the diaphragm using a special vein in your chest, done at the same time as a standard CRT device implant for heart failure. It aims to see if this approach is safe and works well for helping you breathe.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07391995Recruiting
New test for germs in diabetic foot bone infections
This study tests a new device that quickly identifies the germs in foot wounds of people with diabetes and bone infections. It may help doctors choose the right antibiotic faster.
Nîmes, GardAges Any age - NCT07392281RecruitingEarly Phase 1
Macitentan for chest pain from small heart vessel issues
This study tests a medicine called macitentan to see if it helps people with chest pain caused by problems in the tiny heart blood vessels (not from big blockages). If you have angina but no major artery blockages, this trial might explore a new treatment option.
Beijing, Beijing MunicipalityAges 18–75 - NCT07390214Recruiting
Comparing two catheters for repeat atrial fibrillation ablation
This study compares two types of catheters (AFFERA vs. standard contact-force guided) for a repeat ablation procedure in people whose atrial fibrillation or related symptoms returned after a first ablation. It aims to find which catheter works best for a second treatment.
Frankfurt am Main, HesseAges 18–85 - NCT07391280Recruiting
Finding cancer, COPD, and heart failure early in the ER
This trial tests a computer program that looks at chest X-rays to help doctors spot early signs of cancer, COPD (a lung disease), and heart failure. It aims to catch these conditions sooner so patients can get the right care faster.
GlasgowAges 18 years+ - NCT07396857Recruiting
Sitting and blood pressure study for healthy adults
This study tests how substances from your blood vessels (EDHFs) help control blood pressure after you sit for a long time. It may help explain why sitting too much is bad for your heart.
Halifax, Nova ScotiaAges 18–65 - NCT07392801Recruiting
Study on AGE accumulation in long-term parenteral nutrition patients
This study looks at how certain compounds called AGEs build up in the body of people who rely on long-term parenteral nutrition (nutrition given through a vein). It aims to understand whether this affects health and to find better ways to monitor patients.
BordeauxAges Any age - NCT07397923RecruitingPhase 2
Zenicom digital therapy for post-stroke aphasia
This study tests a digital therapy app called Zenicom that may help improve language problems after a stroke. It is for people who had a first stroke in the last 3 months and now have trouble speaking or understanding language.
Seongnam-siAges 19 years+ - NCT07391293Recruiting
Genetic aortic diseases and heart risks observational study
This study looks at people with genetic aortic diseases to understand risk factors for heart complications. By joining, you help researchers learn more about these conditions and how to better manage them.
MilanAges 14–60 - NCT07390331Recruiting
Helping heart patients manage depression
This trial tests a program that helps patients with both depression and heart disease take a more active role in their care. It combines support for depression treatment with your regular heart checkups.
New York, New YorkAges 18 years+ - NCT07391956Recruiting
Palliative care for advanced heart failure or cancer
This study tests whether special supportive care (called tiered palliative care) can help people with advanced heart failure or certain advanced cancers feel better and have fewer hospital visits. If you live in Manhattan or Queens, speak English or Spanish, and meet the other requirements, you may be able to join.
Astoria, New YorkAges 18 years+ - NCT07389434Recruiting
Testing reused catheters for atrial fibrillation treatment
This trial tests whether reusing special catheters to treat atrial fibrillation is safe, effective, and better for costs and the environment. It may help people with atrial fibrillation who need a procedure called pulmonary vein isolation.
ZagrebAges 18 years+ - NCT03718364Recruiting
Atrial fibrillation ablation registry study in Switzerland
This study records information from people undergoing a procedure to treat atrial fibrillation called pulmonary vein isolation. It helps doctors understand how the procedure is used and what outcomes to expect.
BaselAges 18 years+ - NCT05460416RecruitingPhase 3
Aspirin prevention in early pregnancy after frozen embryo transfer
This trial tests whether taking baby-dose aspirin after a frozen embryo transfer can lower the chance of developing pre-eclampsia, a blood-pressure problem that can happen during pregnancy. It targets women considered at higher risk based on specific health factors and pregnancy details.
LiègeAges 18–43 - NCT06325371Recruiting
Study of a Stent for Visceral Artery Aneurysms
This trial tests a special stent called Derivo to treat aneurysms in arteries of the abdomen. It aims to see if this device safely blocks blood flow to the aneurysm and helps prevent rupture.
Torino, TOAges 18 years+ - NCT06568159Recruiting
Sleep apnea treatment in heart patients
This study looks at how well people with heart disease or high heart risk follow their sleep apnea treatment, comparing a mouth device (MAD) to a CPAP machine. It aims to find which treatment works better for daily use.
MontpellierAges 18 years+ - NCT06716840Recruiting
Remimazolam for sedation after heart surgery
This trial tests a medication called Remimazolam Besylate to sedate patients who need a breathing tube after heart surgery. The goal is to help patients relax while they recover in the intensive care unit.
Hangzhou, ZhejiangAges 18 years+ - NCT06831890Recruiting
Smartphone heart risk check study
This study sees if a smartphone app can safely estimate your heart risk without a doctor visit. It's for people who don't have heart disease or diabetes and can use their own phone.
BernAges 40–69 - NCT06832839Recruiting
Cognitive impairment in moyamoya disease study
This study looks at why some people with moyamoya disease have trouble with thinking and memory. It may help find better ways to understand and treat these problems.
Beijing, ChinaAges 18–60 - NCT06832033Recruiting
Exercise program after atrial fibrillation ablation
This trial is testing whether a structured exercise program (combining cardio and strength training) can help people who have already had a procedure to treat atrial fibrillation. It aims to see if this type of training can improve heart health and quality of life.
Zaragoza, ZaragozaAges 18 years+ - NCT04780971Recruiting
Testing heart pressure measurements after a successful CTO stent
This trial studies whether special heart measurements and detailed artery scans (OCT) can better confirm how well a stent procedure worked in people with a blocked coronary artery (CTO). It may help doctors check treatment results more precisely after PCI.
NijmegenAges 18 years+ - NCT03647852Recruiting
Study for difficult IgA vasculitis with gut symptoms
This study looks at treatment strategies for children with IgA vasculitis (also called Henoch-Schönlein purpura) when it mainly affects the stomach and intestines and symptoms do not improve with standard steroid dosing. It may help find better ways to control the illness early and prevent serious complications.
ShanghaiAges 2–16
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,613 recruiting cardiology studies from the U.S. registry right now, out of 14,690 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.