Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT05003986RecruitingPhase 2
Sparsentan for children with protein leaking kidney diseases
This Phase 2 study tests sparsentan in children with certain kidney diseases that cause high amounts of protein in the urine. It aims to see if the medicine can reduce kidney damage signals and protein leakage compared with standard care.
Los Angeles, CaliforniaAges 1–17 - NCT05005793RecruitingPhase 4
Alkali treatment to improve kidney graft blood vessel function
This trial tests whether adding an “alkali” treatment (to raise low blood bicarbonate) can improve blood vessel and kidney graft function in people whose kidney transplant is about 1 year old. It may help if you have lower-than-normal bicarbonate levels while on stable transplant and blood pressure medicines.
Aurora, ColoradoAges 18–80 - NCT05004610RecruitingPhase 2
Hypertonic lactate treatment after cardiac arrest
This trial studies whether giving a specific IV fluid (hypertonic lactate) soon after resuscitation from cardiac arrest can improve recovery. It is for adults who remain in a deep unresponsive state after return of spontaneous circulation.
Brussels, BelgiumAges 18 years+ - NCT05009433Recruiting
Exercise plans in pregnancy and afterward for mom and baby health
This study compares two types of exercise—short, intense intervals versus moderate steady activity—during pregnancy and looks at effects on mothers and children. It also checks how participants do on health, fitness, and well-being tests before, during, and after pregnancy.
Gdansk, Pomeranian VoivodeshipAges 18–45 - NCT05009797Recruiting
Study follow-up after catheter ablation for atrial fibrillation
This trial is looking at what happens after a heart procedure called catheter ablation for atrial fibrillation (an irregular heartbeat). It mainly collects follow-up outcomes to better understand recovery and results for patients.
LilleAges 18 years+ - NCT05011045Recruiting
Brain radiation study tracking thinking and memory changes
This study looks at how whole-brain radiation affects thinking, memory, and other brain function in people with blood cancers that involve the brain. It may help doctors understand what to expect and which supportive treatments or monitoring could be useful.
Houston, TexasAges 18 years+ - NCT05012033Recruiting
Study how high-dose steroids move through the body
This study measures blood levels of high-dose steroid medicines (prednisolone or related steroids) to understand how the body processes them in different real-life situations. It may help improve how steroids are dosed and monitored for people needing short-term or longer-term anti-inflammatory treatment.
LondonAges 18–75 - NCT05013736Recruiting
Study to test recovery in babies with brain injury
This study looks at how well babies recover after certain types of brain injuries that happen around birth, such as stroke, bleeding, or lack of oxygen. You might join if your baby fits the specific age range and has a confirmed injury on brain imaging.
Madison, WisconsinAges birth–2 years - NCT05014802Recruiting
MRI scans before heart surgery to predict post-surgery atrial fibrillation
This study uses an MRI scan before heart surgery to look for heart scarring that may predict who will develop atrial fibrillation afterward. Knowing the risk ahead of time could help doctors monitor you more closely and plan prevention.
Covington, LouisianaAges 40–120 - NCT05015153Recruiting
Rehab after blood clot in the lungs to improve daily life
This study looks at whether pulmonary rehabilitation (a supervised exercise and support program for lung recovery) improves quality of life after a lung blood clot. It focuses on people who have ongoing breathing-related limits after treatment with blood thinners.
Brest, FranceAges 18 years+ - NCT05015452Recruiting
Registry for people who get TAVI
This is a patient registry that collects information from people who receive TAVI, a procedure used to treat certain heart valve problems. It may help doctors better understand who benefits and how patients do over time.
LeipzigAges 18 years+ - NCT05017142Recruiting
Pediatric brain inflammation registry for Swiss patients
This study is a registry that collects health information from children and teens in Switzerland diagnosed with certain inflammatory brain and spinal cord conditions. It helps researchers understand these illnesses better over time and may guide future treatments.
Aarau, Canton of AargauAges Up to 36 years - NCT05015660Recruiting
Testing left bundle pacing versus usual right pacing
This study compares a newer heart pacing method (left bundle branch pacing) to the standard method (right ventricular pacing) in people who need most of their heartbeats paced. It may help improve how well the heart pumps over time.
Montreal, QuebecAges 18 years+ - NCT05021601Recruiting
Ablation method comparison for rheumatic valve and ongoing AF
This study compares two heart procedures—targeting one or both upper heart chambers versus only the left upper chamber—to treat people with ongoing atrial fibrillation caused by rheumatic mitral valve disease. It aims to see which approach works better and is safer for restoring normal rhythm.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05021198Recruiting
Study for people diagnosed with cerebral venous thrombosis
This study is for people who have been diagnosed with cerebral venous thrombosis (a blood clot in the brain’s venous system) at specific hospitals. It looks back at cases from 2014 to 2023 to learn from real-world patients.
LørenskogAges Any age - NCT05021614Recruiting
Valveclip repair study for leaking mitral valve in older adults
This trial tests Valveclip, a catheter-based way to repair a mitral valve that is leaking badly. It may help people who are high-risk for open surgery by aiming to reduce the leak with a less invasive approach.
SichuanAges 60 years+ - NCT05023785Recruiting
Lifestyle program for cancer survivors with early heart strain
This trial tests a structured lifestyle and exercise change program for young people who finished cancer treatment and have signs of early heart weakness. The goal is to improve heart health and lower the chance of heart failure later.
Toronto, OntarioAges 18–45 - NCT05023564Recruiting
Dementia care study following people with a steady caregiver
This study follows people diagnosed with dementia over time, with the help of a consistent caregiver, to better understand how dementia changes. It may help by adding new information that could improve future care and planning for families.
BeijingAges 18 years+ - NCT05024292Recruiting
Alliance study for acute stroke after clot removal
This trial tests a stroke treatment plan for adults after they have a clot removed by a catheter procedure (endovascular treatment). It focuses on people with certain artery blockages and specific scan results, aiming to improve recovery after successful clot removal.
Zhangzhou, FujianAges 18–95 - NCT05024981Recruiting
Video-based feedback and walking rehab after stroke
This trial tests whether using video feedback during walking therapy can help people regain safer walking after a recent stroke. You may be asked to walk while being video-recorded so therapists can guide your practice.
Nice, Alpes-MaritimeAges 70 years+ - NCT05027685Recruiting
Registry for people getting renal nerve ultrasound treatment
This registry follows people who may receive—or recently received—renal denervation using the Paradise ultrasound system. It collects real-world information to help understand safety and effectiveness over time.
ViennaAges 18 years+ - NCT05028686Recruiting
Using blood tests and AI to predict heart failure readmissions
This study looks at hospital and emergency patients with heart failure and uses “omics” (advanced lab data from the body) plus statistics and artificial intelligence to predict who is likely to return to the hospital soon. If it works, it could help doctors better plan follow-up care to reduce repeat hospital visits.
Toronto, OntarioAges 18–105 - NCT05028855Recruiting
Testing brain blood-flow control in recent carotid or MCA narrowing
This study tests how well your brain controls its own blood flow (“cerebral autoregulation”) after a recent TIA or ischemic stroke caused by a narrowed carotid or MCA artery. It may help researchers understand why symptoms happen and how to better assess brain circulation after stroke.
Changchun, JilinAges 18–80 - NCT05029570Recruiting
Heart rate control for permanent atrial fibrillation and heart failure
This trial studies whether a strategy to regularize (control) heart rate can improve outcomes in people who have permanent atrial fibrillation and heart failure. It focuses on people with recent heart-failure hospitalization and checks several heart, kidney, and health-condition limits to keep the study safe.
Madrid, MadridAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.