Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,613 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3438
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke796
- Heart Failure535
- Hypertension389
- Cardiovascular Diseases374
- Coronary Artery Disease362
- Multiple Myeloma328
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona182
- Massachusetts174
- New York166
- Florida141
- Texas122
- Maryland118
- Minnesota118
- Illinois111
Recruiting studies9,613 total
- NCT03481075Recruiting
Personalized CT modeling to plan safer aneurysm stent repair
This study uses your detailed CT scan to create a personalized computer plan for placing a stent inside your enlarged aorta (an abdominal aortic aneurysm). It may help doctors choose the best stent approach for your anatomy during endovascular repair.
Montreal, QuebecAges Any age - NCT04790240RecruitingPhase 1/Phase 2
Herbal treatment aimed to reduce COVID-19 inflammation
This early-stage trial studies whether certain medical herbs can lower inflammation in people with recent COVID-19 and help the immune system better fight the virus. You may be able to join whether or not you take standard COVID medicines, but you would need to complete the herb plan and provide specific lab and scan results.
Rockville, MarylandAges Any age - NCT04766866Recruiting
Check two blood markers to help prevent preeclampsia
This trial tests whether measuring two pregnancy blood markers (sFlt1 and PlGF) and planning delivery timing can help prevent preeclampsia as you reach term. It may help reduce risk for mother and baby by guiding when to deliver based on test results.
LiègeAges 18 years+ - NCT05703191Recruiting
Tests an inhaled nitric oxide system for newborn lung pressure
This study looks at whether an inhaled nitric oxide generator and delivery system can help newborns with high lung blood pressure (pulmonary hypertension). It may help improve oxygen levels during breathing support, but it requires specific medical eligibility and informed consent.
Guangzhou, GuangzhouAges Any age - NCT06101862Recruiting
CT scan vs. angiogram for certain heart attacks
This trial compares two ways to look at heart arteries: a CT scan (noninvasive) versus a traditional angiogram (a tube put into an artery). The goal is to see which is better for people having a certain type of heart attack.
Copenhagen, HellerupAges Any age - NCT06158412RecruitingPhase 2
ATRA plus KPD for relapsed or refractory multiple myeloma
This trial tests a combination of all-trans retinoic acid (a form of vitamin A) with a chemotherapy regimen called KPD for patients whose multiple myeloma has come back or is not responding to standard treatments. The goal is to see if this combination can help control the disease.
Xiamen, FujianAges 18 years+ - NCT06387147RecruitingPhase 3
Oral antibiotics for acute mesenteric ischemia
This trial tests whether taking oral antibiotics (gentamicin and metronidazole) can treat acute mesenteric ischemia caused by an artery blockage, instead of using IV antibiotics. It's for people who don't need emergency surgery and don't have a serious infection.
Clichy, FranceAges 18–90 - NCT06833827Recruiting
Clot removal vs clot-busting drugs for severe lung clots
This study compares two ways to treat a large blood clot in the lungs that is causing life-threatening symptoms. One method uses a device to remove the clot, the other uses medicine to dissolve it.
Leiden, South HollandAges 18 years+ - NCT06427343RecruitingPhase 4
IV iron: low dose vs high dose for heart failure with low iron
This study compares two different doses of IV iron (low vs high) to see which works better for people with heart failure and low iron levels. It may help you feel less tired and breathe easier.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06714344Recruiting
Heart failure therapy support study
This trial tests a new tool to help doctors better manage heart failure treatment. It may be for patients who need IV diuretics for fluid buildup, either in the hospital or at home to avoid hospitalization.
Graz, StyriaAges 18 years+ - NCT07382700Enrolling by invitation
Blood markers in heart attack patients treated with stents
This study looks at certain fats in the blood of people having a severe heart attack called STEMI. Researchers want to see if these fats can help understand what happens in the body during a heart attack.
Ningbo, ZhejiangAges 50–70 - NCT07380490Recruiting
Comparing two heart-opening closure devices after a stroke or TIA
This trial compares two devices that close a small opening in the heart called a PFO, which can let clots pass and cause strokes. If you've had a stroke or mini-stroke with no other cause, this study might help prevent future ones.
Bad Oeynhausen, North Rhine-Westphalia (Nordrhein-Westfalen)Ages 18–65 - NCT07379840Recruiting
Finerenone for chronic heart failure in South Korea
This trial tests how safe and effective finerenone is for adults with chronic heart failure. It includes people whose heart pumps blood with at least 40% efficiency.
Multiple LocationsAges 19 years+ - NCT07388355Recruiting
Ease of use study for a new heart monitor device
This study tests how easy it is to use a new device that records your heart's electrical activity through a simple patch on your chest. You will need to use a smartphone app with the patch.
New London, North CarolinaAges 18 years+ - NCT07385625Recruiting
Studying a new device for severe tricuspid valve leakage
This trial tests a device called the Pivot Bridge System to treat severe leakage of the tricuspid valve (the valve between the right upper and lower heart chambers). The goal is to see if it safely reduces symptoms like swelling and shortness of breath.
Daegu, Dalseo-guAges 18 years+ - NCT07383025Recruiting
Mavacamten safety study for heart muscle disease in Japan
This study tracks the safety of Mavacamten in people with obstructive hypertrophic cardiomyopathy (a condition where the heart muscle thickens and blocks blood flow). It helps doctors understand how the drug works in everyday use in Japan.
TokyoAges 18 years+ - NCT07385599Recruiting
Study of a new heart device for atrial fibrillation patients
This trial tests a new device called LAmbre™ II that closes off a part of the heart called the left atrial appendage to help prevent strokes in people with atrial fibrillation who cannot take blood thinners.
ShatinAges 18 years+ - NCT06836011Recruiting
Heart valve leakage study in a type of amyloid heart disease
This study looks at how common and how serious heart valve leaks are in people with transthyretin amyloid cardiomyopathy (a condition where abnormal protein builds up in the heart). The goal is to better understand these leaks and how they affect long-term health.
Graz, StyriaAges 18 years+ - NCT05868902Recruiting
Study registry of heart imaging for suspected blocked heart flow
This study collects results from two types of heart imaging—cardiac PET and CardioFlux magnetocardiography—in people with suspected reduced blood flow to the heart. It may help researchers better understand which imaging findings match coronary ischemia and how the tests compare.
Cleveland, OhioAges 40 years+ - NCT07380217Recruiting
Using heart pump support for complex high-risk procedures
This trial is testing whether using a special heart pump (PulseCath iVAC2L) during complex, high-risk angioplasty can help people with very weak hearts. It's for people who need a procedure for complicated coronary artery blockages.
AmsterdamAges 18 years+ - NCT07380243Recruiting
Food for Health: A Prevention Trial for Families
This trial tests if giving healthy food to families can improve health and prevent disease. It's for parents with a high BMI who have a child between 6 and 11 years old.
Columbus, OhioAges 6 years+ - NCT07387328Recruiting
Testing new sensor placement for leg muscles in stroke survivors
This study checks if new guidelines for placing sensors on leg muscles work well in people who have had a stroke. It could help improve how we measure muscle activity during walking and other movements.
Ghent, Oost-VlaanderenAges 18 years+ - NCT07385417Recruiting
Early AF treatment for heart failure with preserved pumping function
This study tests using a new electrical pulse treatment for atrial fibrillation (AF) early on, in people who also have a type of heart failure where the heart pumps normally but is stiff. The goal is to see if this treatment helps manage both conditions better.
Frankfurt am MainAges 18–80 - NCT07388108Recruiting
Predicting heart rhythm problems after heart surgery
This trial studies whether measuring how the upper chambers of the heart work together can help predict dangerous heart rhythms after heart surgery. If you are in normal heart rhythm and not having mitral valve surgery, this study may help doctors better prevent complications.
Mendoza, MendozzAges 18–80
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,613 recruiting cardiology studies from the U.S. registry right now, out of 14,690 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
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- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.