Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT06126367Recruiting
Study on lipoprotein(a) and clot breakdown in heart disease
This trial looks at how a type of fat in the blood called lipoprotein(a) and your body's ability to break down clots affect heart disease or heart valve disease. It is for people who are already taking certain cholesterol-lowering medicines or have severe aortic valve narrowing from calcium buildup.
StevenageAges 18 years+ - NCT06127927Recruiting
Heart pump for severe heart failure
This trial is testing a temporary heart pump device that helps your heart pump blood when it's too weak to do its job. It's for people who have severe heart failure (cardiogenic shock) despite getting powerful medications to keep their heart working.
Fuzhou, FujianAges 18–75 - NCT06128317Recruiting
Heart attack and chest pain registry study
This study is a registry that collects information from people who come to the hospital with heart-related symptoms like chest pain or high troponin levels. It helps doctors better understand different heart conditions and improve care.
Heidelberg, Baden-WurttembergAges 18 years+ - NCT06128629RecruitingPhase 3
A study of NTLA-2001 for transthyretin amyloidosis with heart problems
This study tests a new treatment, NTLA-2001, for people with a type of heart disease called transthyretin amyloidosis with cardiomyopathy. It aims to see if the medicine can help improve heart function and quality of life.
Tucson, ArizonaAges 18–90 - NCT06128993Recruiting
cooling the heart during heart attack treatment
This trial tests a new way to protect the heart during emergency angioplasty by gently cooling the heart with a cold fluid. It may help reduce damage from a heart attack if you are treated within 12 hours.
UxbridgeAges 18 years+ - NCT06129175RecruitingPhase 2/Phase 3
Stem cells for recent moderate to severe stroke
This trial is testing a new treatment using stem cells from donated umbilical cord tissue to help people recover from a recent moderate to severe stroke. It is for patients who cannot receive standard clot-busting treatments.
Cheras, Kuala LumpurAges 18 years+ - NCT06129240Recruiting
Study of a new inhaled treprostinil powder for PH-ILD
This study tests a new dry powder inhaled medicine called LIQ861 for people with pulmonary hypertension related to lung scarring (PH-ILD). If you are already taking an inhaled treprostinil treatment but need better control, this trial may help you switch to a potentially easier-to-use version.
Phoenix, ArizonaAges 18–80 - NCT06129799Recruiting
Exercise heart MRI for low-flow aortic stenosis
This trial uses a special heart MRI scan before and after exercise to study blood flow in people with a type of aortic stenosis where the heart's pumping function may be reduced. It could help doctors better understand how to treat this condition.
GöttingenAges 18 years+ - NCT06129656Recruiting
Cardiac Amyloidosis Registry at Leipzig Hospital
This study is a registry that collects information from people with cardiac amyloidosis. It helps doctors learn more about the condition and how to better treat it.
Leipzig, SaxonyAges Any age - NCT06130059RecruitingPhase 2
Low-dose colchicine for heart failure with inflammation
This trial tests whether a low-dose colchicine (LoDoCo) can help people with heart failure and inflammation feel better and exercise more. It is for adults 50 and older with HFpEF who have signs of inflammation in their blood.
Dallas, TexasAges 50 years+ - NCT06131385Recruiting
Tracking IV clot-busting treatment for stroke in China
This study is tracking patients in southwestern China who have had an acute ischemic stroke and received a clot-busting medicine through an IV. It aims to learn more about how well this treatment works and how it is used in real-world settings.
LuzhouAges Any age - NCT06132451Recruiting
In-hospital blood pressure check for non-heart patients
This trial checks if patients hospitalized for non-heart-related reasons have high blood pressure that went unnoticed. It may help find and manage high blood pressure early.
BaselAges 18 years+ - NCT06132399Recruiting
Virtual reality software for recent stroke recovery
This trial tests whether using virtual reality exercises can help people who recently had a stroke regain movement in their arms or legs. If you had a stroke 7 to 14 days ago and have weakness on one side, this study may help with your recovery.
Almería, AlmeríaAges 18 years+ - NCT06132477RecruitingPhase 4
Study of GLP-1 medicines after weight loss surgery
This study looks at what happens when people taking a GLP-1 medication (like Ozempic) either stop or continue it after weight loss surgery. The goal is to learn whether staying on the medicine helps with long-term weight control.
Columbia, MissouriAges 18 years+ - NCT06132711RecruitingPhase 1/Phase 2
CAR-T therapy for relapsed multiple myeloma
This trial tests a new kind of CAR-T cell therapy (called APRIL-BAFF-Bicephali CAR-T) for people with multiple myeloma that has come back or not responded to treatment. It aims to see if this therapy is safe and can help when other treatments have stopped working.
Xuzhou, JiangsuAges 18–70 - NCT06132984Recruiting
Heart MRI monitoring for immunotherapy-related heart issues
This study uses heart MRIs to monitor women with gynecologic cancers who are about to start immunotherapy. The goal is to detect early signs of heart problems so doctors can take action quickly.
Chengdu, SichuanAges 18–75 - NCT06133179Recruiting
Super-resolution brain ultrasound for stroke patients
This trial tests a new 3D ultrasound technique to get clearer images of blood flow in the brain after a stroke, which could help doctors better understand and treat the damage.
Paris, Île-de-France RegionAges 18 years+ - NCT06133322Recruiting
Blood pressure study for church communities in New Orleans
This study looks at different ways to lower blood pressure in church communities. It aims to find the best methods to reduce high blood pressure, especially in groups that are often affected by it.
New Orleans, LouisianaAges 18 years+ - NCT06133426Recruiting
Connected scales for blood cancer patients at home
This trial tests if using a connected scale to monitor your weight at home can help your doctors manage your treatment for aggressive non-Hodgkin's lymphoma or multiple myeloma. It may also apply if you need a stem cell transplant (autograft) for these conditions.
ParisAges 18 years+ - NCT06135909Recruiting
CHASE registry for pulmonary hypertension patients on treatment
This study is a registry that collects information on people with pulmonary hypertension who are using or starting targeted medications. The goal is to understand how these treatments work in real-world settings and improve care for patients like you.
BeijingAges 18–85 - NCT06136429Recruiting
A study of a new valve device for severe aortic stenosis
This trial tests a new valve device placed through a small tube (catheter) to treat severe aortic stenosis, a condition where the aortic valve is narrowed and doesn't open fully. It's for patients who cannot have traditional open-heart surgery.
BeijingAges 70 years+ - NCT06137547Recruiting
Preventing low blood pressure during heart surgery with HPI
This trial tests a new method (called HPI) to prevent dangerously low blood pressure during planned heart surgery. It is for adults having bypass surgery or valve surgery, but not for those with certain heart rhythm problems or needing emergency surgery.
TaipeiAges 18 years+ - NCT06137521Recruiting
Heart artery blockage study
This study looks at people with a long-standing complete blockage in a heart artery. The goal is to understand risk factors and outcomes, which may help guide future treatments.
ShanghaiAges 18 years+ - NCT06138873Recruiting
Study of scar-guided ablation for ventricular tachycardia
This trial is testing a new approach to treating a fast, dangerous heart rhythm (ventricular tachycardia) that comes from scar tissue in people with ischemic cardiomyopathy. The goal is to use a special mapping technique to guide the ablation (a procedure that destroys the tiny area causing the problem) to stop the arrhythmia.
Chicago, IllinoisAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.