Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT06118372RecruitingPhase 1
Recombinant vWF concentrate for bleeding on ECMO
This trial tests whether a medication called recombinant von Willebrand factor (vWF) can help control major bleeding in adults who are on life support with ECMO. If you are on ECMO and have a serious bleed, this treatment might help stop the bleeding.
Charlottesville, VirginiaAges 18 years+ - NCT06118840Recruiting
AI tool for spotting brain aneurysms on CT scans
This trial tests if an AI model can help doctors detect brain aneurysms more accurately on head CT angiograms (CTA). It may lead to earlier treatment and better outcomes.
Hefei, AnhuiAges 18 years+ - NCT06119061RecruitingPhase 4
Telavancin levels in patients with external ventricular drain
This study measures how much of the antibiotic telavancin reaches the fluid around your brain and spine when you have a drain in place. It will help doctors understand if this drug is effective for treating brain infections.
Lexington, KentuckyAges 18–85 - NCT06119685RecruitingPhase 1/Phase 2
IDP-023 alone or with other antibodies for blood cancers
This trial tests an experimental drug, IDP-023, given alone or with antibody therapies for people with advanced blood cancers like multiple myeloma or non-Hodgkin lymphoma that have not responded to previous treatments. The goal is to see if it can shrink tumors or slow the disease.
Los Angeles, CaliforniaAges 18 years+ - NCT06120049RecruitingPhase 2/Phase 3
Comparing new PET scans for Parkinson's, MSA, Lewy body dementia, and Alzheimer's
This study tests if a new radioactive tracer called [18F]-MFBG can help doctors better distinguish between Parkinson's disease, multiple system atrophy (MSA), dementia with Lewy bodies, and Alzheimer's disease. It compares the new scan with two standard scans to see which is most accurate.
Ghent, GentAges 18–85 - NCT06120218Recruiting
Stenting for blocked neck and brain artery in severe stroke
This trial tests a treatment for people having a severe stroke when a large artery in the neck and a brain artery are both blocked. The treatment involves opening the neck artery with a stent (a small tube) and then clearing the brain clot, all within 24 hours of symptom onset.
Can ThoAges 19–100 - NCT06120361Recruiting
Primary care study for early cognitive decline
This research study looks at people who have noticed problems with memory or thinking (like trouble focusing or finding words) and visit their primary care doctor for help. It aims to better understand and diagnose conditions that cause these symptoms, such as Alzheimer's disease.
MalmöAges 40 years+ - NCT06120270Recruiting
CeraFlex PFO closure study for migraine or stroke
This study tests a device called CeraFlex PFO Occluder to close a small hole in the heart (PFO) that may be causing migraines or strokes. If you have a PFO with related symptoms, the device might help prevent future events.
BremenAges 18–85 - NCT06120400RecruitingPhase 3
Heart health effects of eating eggs in a healthy diet
This study tests whether adding eggs to a healthy diet can improve heart health markers like cholesterol and blood pressure in adults who are overweight but generally healthy. It may be a good fit if you are not already eating many eggs and are willing to follow a specific menu.
University Park, PennsylvaniaAges 30–60 - NCT06121219Recruiting
Can visual retraining after stroke improve sight?
This trial tests whether special computer-based visual exercises can help people whose vision was damaged by a stroke. You would do the exercises at home for several months.
Rochester, New YorkAges 21–80 - NCT06122246Recruiting
Pressure Check: Find your path to better health
This trial helps people with high blood pressure learn ways to improve their health. It tests if a program can help you lower your blood pressure.
New Haven, ConnecticutAges 18 years+ - NCT06122337Recruiting
Finding causes of cardiac arrest in young adults
This study looks at why young adults have a cardiac arrest (when the heart suddenly stops pumping) outside the hospital, with no injury involved. It aims to better understand causes such as heart, genetic, or other medical issues.
TaipeiAges 18–60 - NCT06122415Recruiting
Memory clinic study with fluid and cognitive tests
This study looks at people who are being checked for memory or thinking problems. It uses standard tests done at the memory clinic, like a spinal tap and blood draw, plus memory and thinking tests, to learn more about these symptoms. You can join if these tests are already planned as part of your regular care, even if you don't take part in the study.
MalmöAges Any age - NCT06123325Recruiting
Mental health and quality of life after unruptured brain aneurysm diagnosis
This trial looks at how being diagnosed with an unruptured brain aneurysm (a weak spot on a blood vessel that hasn't bled) affects your mood, anxiety, and quality of life. It also compares outcomes for people who get treatment (like surgery or a catheter procedure) versus those who are watched with scans.
The Bronx, New YorkAges 18–75 - NCT06123377Recruiting
Blood Markers for Managing High Blood Pressure in Pregnancy
This study looks at whether certain blood markers (called angiogenic factors) can help manage high blood pressure in pregnancy without having to deliver the baby early. If you have gestational hypertension, this trial may help doctors decide the best way to keep you and your baby healthy.
Panama City, Provincia de PanamáAges 18 years+ - NCT06123650Recruiting
Magnetic brain stimulation plus therapy for swallowing after stroke
This study tests whether adding a gentle magnetic brain stimulation (called rTMS) to standard swallowing therapy can help prevent pneumonia in people who have trouble swallowing after a stroke. It might reduce the risk of getting a lung infection.
Giza, Giza GovernorateAges 49–65 - NCT06124196Recruiting
Wearable device study for Duchenne muscular dystrophy
This study uses a wearable device to track your blood sugar levels and heart rate patterns over time. It aims to understand how these are related to Duchenne muscular dystrophy (DMD) and may help improve care.
Nashville, TennesseeAges 10 years+ - NCT06124248Recruiting
RISE program to help stroke survivors sit less and move more
This study tests if a program called RISE can help people who have had a stroke reduce the amount of time they spend sitting. The goal is to see if it helps improve recovery and daily life after returning home from the hospital.
's-Hertogenbosch, North BrabantAges 18 years+ - NCT06124586Recruiting
Early angioplasty for diabetic foot ulcers
This trial tests if an early procedure to open blocked leg arteries (angioplasty) helps heal foot ulcers in people with type 2 diabetes. It aims to improve blood flow and prevent amputation.
DüsseldorfAges 18 years+ - NCT06124768Recruiting
Comparing two blood clot removal methods for leg clots
This trial compares two ways of doing a mechanical blood clot removal procedure for people with a new deep vein thrombosis (a blood clot in a deep vein, often in the leg). The goal is to see which method works better.
Shanghai, Shanghai MunicipalityAges 18–85 - NCT06124612Recruiting
Blood sample study for people in the OCEANIC-AF trial
This study collects blood samples from people already taking part in the OCEANIC-AF trial. It aims to learn more about the effects of the treatment being tested.
LiverpoolAges 18 years+ - NCT06125392Recruiting
New Definition for Small Heart Vessel Disease
This trial studies a condition where small heart vessels don't work well. It looks at new ways to define this problem using a special test that measures pressure and blood flow in a heart artery.
Mainz, Rhineland-PalatinateAges 18–90 - NCT06125236Recruiting
Stroke study for large artery blockages in Southwest China
This study is collecting information from people in Southwest China who have had a stroke caused by a blocked large or medium artery. The goal is to learn more about these strokes and how to treat them better.
LuzhouAges Any age - NCT06125925Recruiting
Ablation for AFib in patients with heart failure and preserved ejection fraction
This study tests whether a catheter ablation procedure can help people with atrial fibrillation and a kind of heart failure where the heart pumps normally but doesn't relax properly (HFpEF). It looks at whether the procedure can improve symptoms and heart function.
NanjingAges 18–80
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.