Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT06139692RecruitingPhase 4
Comparing light sedation during clot removal for stroke
This study compares two types of light sedation (medication to help you relax) during a procedure to remove a blood clot in the brain after a stroke. The goal is to find which sedation method helps patients recover better.
Nanjing, None SelectedAges 18 years+ - NCT06140537RecruitingPhase 4
Dapagliflozin for kidney and heart health after transplant
This study tests whether a diabetes drug called dapagliflozin (Farxiga) can help protect your kidney function and heart health after a kidney transplant. It's for people who have had a transplant for at least a year and have diabetes or post-transplant diabetes.
Aurora, ColoradoAges 18–80 - NCT06140966RecruitingPhase 2
Daratumumab and Carfilzomib combo for high-risk multiple myeloma
This trial tests a combination of the drugs daratumumab, carfilzomib, lenalidomide, and dexamethasone given before and after a stem cell transplant for people with ultra high-risk multiple myeloma. The goal is to see if this regimen is safe and more effective than standard treatments.
Wuhan, HubeiAges 18–70 - NCT06141525Recruiting
Remote conditioning for safer heart bypass recovery
This study tests whether a simple, non-invasive treatment called remote ischemic conditioning (using a blood pressure cuff on your arm) can help patients recover better after off-pump heart bypass surgery. The goal is to see if it reduces complications and improves heart function.
Xi'an, ShaanxiAges 18–70 - NCT06141811Recruiting
Long-term safety study for diabetic foot ulcer treatment
This study follows up on patients who received an experimental cell sheet (ALLO-ASC-DFU) or a placebo in a previous trial. It checks for any new safety concerns over time.
Bucheon-si, Gyeonggi-doAges 19–75 - NCT06142396RecruitingEarly Phase 1
Dara-CyBorD for New Multiple Myeloma with Kidney Failure
This pilot study tests a combination of four drugs (daratumumab, cyclophosphamide, bortezomib, and dexamethasone, known as Dara-CyBorD) in people newly diagnosed with multiple myeloma who also have kidney problems. The goal is to see if this treatment is safe and effective for this specific group.
Augusta, GeorgiaAges 18–80 - NCT06143488Recruiting
Clot removal vs. best medicine for mild stroke with large vessel blockage
This trial tests whether removing a blood clot from a large brain artery is better than standard medical care for people who have a mild stroke (NIHSS score 2-5) but still have symptoms like trouble speaking, weakness, or confusion. It is for patients who can be treated within 24 hours of their last known well time.
Wuhu, AnhuiAges 18 years+ - NCT06143566RecruitingPhase 1/Phase 2
Polypill to prevent heart failure in diabetes and kidney disease
This trial tests a 'polypill' (a combination of several medicines in one pill) to prevent heart failure in people with type 2 diabetes and kidney disease. It may help reduce your risk of developing heart muscle problems.
Dallas, TexasAges 18–100 - NCT06143969Recruiting
Ultrasound-guided clot-dissolving treatment for intermediate-high risk pulmonary embolism
This trial tests a treatment that uses ultrasound to guide a thin tube (catheter) to deliver clot-busting medicine directly into the blood clot in your lung. It may be an option for people whose clot is serious but not yet causing shock, and who have symptoms that started within the last two weeks.
Milan, ItaliaAges 18 years+ - NCT06144125RecruitingPhase 4
Blood management trial for heart surgery patients
This trial compares two treatments (prothrombin complex concentrate and fresh frozen plasma) for managing bleeding during heart surgery. It aims to find which approach works better and is safer for patients.
Seoul, SeoulAges 20–75 - NCT06145035RecruitingPhase 2
Stem cells from cord blood for heart failure
This trial tests whether stem cells from donated umbilical cord blood can improve heart function in people with heart failure caused by blocked arteries. You'll receive one or more infusions of these cells through a vein.
Miami, FloridaAges 21–85 - NCT06145581Recruiting
Remote health coaching for older myeloma patients with fatigue
This study tests whether remote monitoring and health coaching can improve quality of life in older adults with multiple myeloma who are experiencing fatigue. You'll use a tablet or smartphone to track symptoms and get support from a coach.
Rochester, MinnesotaAges 65 years+ - NCT06145893RecruitingPhase 3
Hemay005 for Behçet's disease mouth sores
This study tests a new pill called Hemay005 for adults with Behçet's disease who have at least two mouth sores that need treatment beyond creams or rinses. It aims to see if the drug safely reduces mouth ulcers.
Beijing, Beijing MunicipalityAges 18–75 - NCT06145906Recruiting
Optimizing catheter ablation for atrial fibrillation
This trial is studying a way to improve the entire process of catheter ablation for atrial fibrillation. It may help people who are having this procedure for the first time and have a normal-sized left atrium and good heart function.
Zhengzhou, HenanAges 18–80 - NCT06146660Recruiting
Mavacamten safety study in Korean patients with oHCM
This study checks how safe the drug mavacamten is for Korean patients with a type of heart disease called obstructive hypertrophic cardiomyopathy (oHCM). It is for people who are already prescribed the drug by their doctor.
SeoulAges 19 years+ - NCT06146751Recruiting
Improved MRI to detect blood clots in the heart
This trial tests a new type of MRI with a special dye (ferumoxytol) to better find blood clots in the heart. It is for people who have a left ventricular aneurysm (a bulging area in the heart's main pumping chamber) or who had a heart procedure called percutaneous ventricular reconstruction about 6 months ago.
Nanjing, JiangsuAges 18–80 - NCT06146790Recruiting
Endovascular treatment for strokes in smaller brain arteries
This trial tests a minimally invasive procedure to remove blood clots from smaller arteries deep inside the brain. It may help people with moderate to severe stroke symptoms who can be treated within 24 hours of symptom onset.
Hefei, AnhuiAges 18 years+ - NCT06147024Recruiting
Using 3D printed models to plan aneurysm surgery
This study uses a 3D printed model of your artery bulge (aneurysm) to help your surgeon plan the operation before surgery. It may help make the surgery safer and more personalized.
New Taipei CityAges 18–80 - NCT06147336Recruiting
Testing the V-Lap system for heart failure monitoring
This trial tests a new device called V-Lap that is placed in the heart to monitor pressure. It may help doctors better manage heart failure and reduce hospital stays. Researchers want to see if it works well in people with mild to moderate heart failure.
Boston, MassachusettsAges 22–88 - NCT06147986RecruitingPhase 2
Stem cell treatment after heart attack
This trial tests if umbilical cord stem cells, given alongside standard care, can help people who have had a major heart attack (STEMI). The cells are infused into the heart artery to possibly improve heart function. You may qualify if you are between 20 and 76, had a heart attack within the last 12 hours, and received a stent, and your heart's pumping ability is moderately reduced.
TaichungAges 20–75 - NCT06148051Recruiting
Australian CADASIL study: learning more about this condition
This study is building a group of Australians with CADASIL (a genetic condition that affects blood vessels in the brain) to learn more about the disease. As a participant, you will have a medical exam, a blood test, and a short memory test.
Newcastle, New South WalesAges 18 years+ - NCT06148285Recruiting
Hyperbaric oxygen for ischemic stroke recovery
This study tests whether hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) can help people recover after a recent ischemic stroke. It is open to stroke survivors admitted to Touro's inpatient rehab unit.
New Orleans, LouisianaAges 18 years+ - NCT06148883Recruiting
Managing new heart block after TAVI
This study looks at people who develop a new heart block (left bundle branch block) after having a minimally invasive aortic valve replacement. Researchers want to find the best way to manage this condition to prevent future heart problems.
MarseilleAges 18 years+ - NCT06149910Recruiting
Study of Treatment Plans for Newly Diagnosed Multiple Myeloma
This study looks at whether a new treatment plan (called a clinical pathway) helps doctors make better decisions for people just diagnosed with multiple myeloma. It will review medical records and may ask you to use a secure online platform to share your health information.
Seattle, WashingtonAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.