Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,976 recruiting studies in this area right now.
By phase
- Not applicable7,959
- Phase 2483
- Phase 4479
- Phase 3447
- Phase 1361
- Phase 1/Phase 2161
- Phase 2/Phase 386
Top conditions
- Stroke841
- Heart Failure567
- Hypertension401
- Cardiovascular Diseases390
- Coronary Artery Disease372
- Multiple Myeloma334
- Atrial Fibrillation268
- Ischemic Stroke201
- Atrial Fibrillation (AF)140
- Acute Ischemic Stroke137
- Myocardial Infarction102
- Pulmonary Hypertension100
- Congenital Heart Disease85
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California460
- Alabama197
- Massachusetts183
- Arizona174
- New York161
- Florida145
- Maryland120
- Illinois119
- Minnesota119
- Texas118
Recruiting studies9,973 total
- NCT06469801Recruiting
Portable MRI for brain injury in children on ECMO
This study uses a portable MRI to look for brain injuries in children on ECMO (a heart-lung support machine). It may help doctors detect problems early and improve care.
Kansas City, MissouriAges birth–17 years - NCT07758582Recruiting
Artificial intelligence for detecting diabetic retinopathy from eye photos
This study tests an AI system that automatically detects signs of diabetic retinopathy from eye photos. It aims to see if the AI can accurately identify these signs to help with early detection.
AlexandroupoliAges 18 years+ - NCT07426484RecruitingPhase 4
Testing cosibelimab for advanced skin cancer in specific patients
This trial tests an immunotherapy drug called cosibelimab for patients with advanced cutaneous squamous cell carcinoma who have either had a kidney transplant or have a blood cancer like lymphoma or myeloma. The goal is to see if it can shrink tumors when surgery or radiation is not an option.
Boston, MassachusettsAges 18 years+ - NCT05230732Recruiting
Test a nerve-stimulation approach for heart inflammation
This trial studies a nerve-stimulation treatment to affect inflammation and blood vessel function in people with systolic heart failure. If you qualify, it may help improve how your heart and blood vessels work.
Oklahoma City, OklahomaAges 18–85 - NCT07724522Recruiting
Prebiotic Fiber for Irregular Periods in Women
This study tests whether taking a prebiotic fiber (inulin) can help women who are in the later years of their reproductive life (before menopause) and have irregular periods. You may be eligible if you are overweight, have irregular cycles, sit a lot, and do not exercise much.
Washington D.C., District of ColumbiaAges 40–55 - NCT07759063Enrolling by invitation
Self-paced walking study for stroke or brain injury survivors
This study tests a new way to help people who have had a stroke or brain injury walk with a more even step. It uses a treadmill that adjusts to your own pace, which may improve your walking symmetry.
Omaha, NebraskaAges 19–75 - NCT06939751Recruiting
Testing microRNA levels to personalize heart transplant care
This trial is studying whether a blood test that measures small molecules called microRNAs can help doctors personalize the medicines used to prevent rejection after a heart transplant. If you qualify, you would help researchers learn how to better match immunosuppression to each patient's needs.
Los Angeles, CaliforniaAges 18–99 - NCT07727395RecruitingPhase 3
Clot-busting drug after successful clot removal for stroke
This trial tests whether giving a clot-busting drug (alteplase) directly into the brain artery after a successful clot removal improves recovery in people with severe stroke. It is for patients who have had a thrombectomy and still have a large blocked artery in the front of the brain.
An GiangAges 18 years+ - NCT07335341Recruiting
Liberant thrombectomy system case survey
This survey collects feedback from doctors who used the Liberant system to remove blood clots. The results help understand how well the device works in real-life procedures.
Washington D.C., District of ColumbiaAges 22 years+ - NCT04840797Recruiting
Registry for HeartStart HS1 use during suspected cardiac arrest
This study collects real-world information about people who had a suspected cardiac arrest and where the HeartStart HS1 defibrillator was used with specific Philips pad types. It may help improve how emergency teams respond in the future.
Pittsburgh, PennsylvaniaAges Any age - NCT06150560Enrolling by invitationPhase 3
Blood pressure medicine study for people with repaired coarctation of the aorta
This trial tests a type of blood pressure medicine (an angiotensin-II receptor blocker) to see if it can help prevent changes in the heart's structure. It is for people who have had surgery for a coarctation of the aorta and now have mild to moderate high blood pressure.
Rochester, MinnesotaAges 18 years+ - NCT07187687Recruiting
Early minimally invasive clot removal for brain hemorrhage
This study tests if removing a large brain clot early using a small tube and clot-dissolving medicine can improve recovery after a hemorrhagic stroke. It is for people with a moderate to large bleed who can start treatment within 12 hours of symptoms.
Guangdong, YuexiuAges 18 years+ - NCT07544979Recruiting
Decision Aid for Coronary Artery Anomalies
This study creates a tool to help patients and families with a rare heart condition called R-AAOCA (right anomalous aortic origin of a coronary artery) make informed decisions about their care. The tool aims to improve understanding and shared decision-making between patients and doctors.
Boston, MassachusettsAges 10–35 - NCT07690982Recruiting
Posture and movement study for stroke survivors
This study uses a device called PhysioMaster to measure posture and range of motion in people who have had a stroke. It aims to help understand and improve recovery after a stroke.
IstanbulAges 40–70 - NCT07288216RecruitingPhase 2
Switching to KPL-387 alone for well-controlled pericarditis
This study tests whether a new drug, KPL-387, can keep your pericarditis under control as your only treatment, after you have been stable on other medicines. It is for people whose pericarditis is well controlled now but who have had flares in the past.
Phoenix, ArizonaAges 18–80 - NCT07268391Recruiting
Advanced scans to understand heart healing after heart attack
This study uses advanced CT scans and blood tests to look at how the heart is damaged and recovers after a first heart attack. It may help doctors find better ways to treat heart attacks in the future.
MadridAges 18 years+ - NCT06827990Recruiting
Stent graft for type A aortic dissection
This trial tests a stent graft device to repair a tear in the main artery from the heart (aorta). It is for people who have a high-risk condition called Type A aortic dissection and are not good candidates for open heart surgery.
Birmingham, AlabamaAges 18 years+ - NCT07228065Enrolling by invitation
Combination pill study for better blood pressure control
This trial tests whether switching to a single pill that combines two blood pressure medicines helps control high blood pressure better than taking two separate pills. It might make treatment simpler and more effective.
Milwaukee, WisconsinAges 18–80 - NCT04250857Recruiting
HeartStart AED event registry for suspected sudden cardiac arrest
This study records information about people who were suspected of having a sudden heart stoppage. It may help improve how emergency responders use this specific AED (automated defibrillator).
Monroeville, PennsylvaniaAges Any age - NCT07218094Enrolling by invitation
Exosuit walking study for chronic stroke survivors
This study tests a robotic leg suit (exosuit) to help improve walking after a stroke. You may be eligible if you had a stroke more than 6 months ago and still have trouble walking safely.
Boston, MassachusettsAges 18 years+ - NCT06355934Recruiting
Observational study of ATTR amyloidosis treatment patterns
This study looks at the health records of people with ATTR amyloidosis to understand how the disease is treated and what happens over time. It helps doctors learn more about this condition so they can improve care.
Eden Prairie, MinnesotaAges Any age - NCT07637578RecruitingPhase 2
Elranatamab infusions for relapsed or refractory myeloma
This study tests a new drug called elranatamab given as outpatient infusions for multiple myeloma that has come back or stopped responding to prior treatments. The drug is designed to help your immune system fight the cancer cells.
Denver, ColoradoAges 18 years+ - NCT07131696Recruiting
Vagus nerve stimulation for brain bleeding complication
This trial tests if a nerve stimulation device can prevent a dangerous blood vessel spasm after a brain aneurysm bleed. It may help reduce damage and improve recovery.
Birmingham, AlabamaAges 18–65 - NCT05485961RecruitingPhase 2/Phase 3
Clazakizumab for kidney failure patients on dialysis
This study tests an experimental drug called clazakizumab (CSL300) to see if it can reduce inflammation and lower the risk of heart problems in people with kidney failure who are on dialysis. It may help if you have diabetes or heart disease and have high inflammation levels.
Decatur, AlabamaAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,976 recruiting cardiology studies from the U.S. registry right now, out of 15,179 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
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- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.