Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,609 recruiting studies in this area right now.
By phase
- Not applicable7,632
- Phase 4472
- Phase 2469
- Phase 3439
- Phase 1350
- Phase 1/Phase 2160
- Phase 2/Phase 387
Top conditions
- Stroke797
- Heart Failure534
- Hypertension388
- Cardiovascular Diseases373
- Coronary Artery Disease363
- Multiple Myeloma327
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction97
- Congenital Heart Disease84
- Peripheral Arterial Disease79
- Stroke, Ischemic78
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital68
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California453
- Alabama196
- Arizona181
- Massachusetts173
- New York168
- Florida140
- Texas122
- Maryland118
- Minnesota117
- Illinois112
Recruiting studies9,609 total
- NCT05985213Recruiting
Brain blood vessel disease study at Yueyang Hospital
This study follows people with small vessel brain disease to understand how it changes over time. You may join if you've had an MRI showing this type of brain change and are able to take care of yourself daily.
ShanghaiAges 18–80 - NCT05985447Recruiting
Menopause and blood cell function study
This study looks at how menopause affects blood cells and platelets in people with heart or lung conditions. It may help understand why risks change after menopause.
DüsseldorfAges 18 years+ - NCT05916287Recruiting
STANISLAS cohort follow-up visit for heart and kidney health
This study is a follow-up visit for people who joined the STANISLAS family health cohort. Researchers look at how genes and environment may affect heart and kidney (kidneys) health over time.
Vandœuvre-lès-Nancy, LorraineAges Any age - NCT05994274Recruiting
Heart transplant, cholesterol, and organ rejection study
This study looks at whether changes in blood fats (cholesterol and triglycerides) after a heart transplant are linked to the risk of organ rejection. It may help doctors better monitor and protect your new heart.
WuhanAges 18 years+ - NCT05991219Recruiting
Rheumatic heart disease screening and prevention study
This study is looking for people living in rural areas of Sindh, Pakistan, to help screen for and prevent rheumatic heart disease. It aims to find and treat the condition early.
Karachi, SindhAges 10–30 - NCT05996367Recruiting
Single radiation dose for painful myeloma bone lesions
This trial is testing whether a single dose of radiation can effectively relieve bone pain caused by multiple myeloma. It is designed for people who have a painful bone lesion and are stable on or off treatment.
São Paulo, São PauloAges 18–85 - NCT05046483Recruiting
Blood sugar study after a new heart attack
This study measures how your body handles sugar and related hormones in people after a new STEMI heart attack, and compares them with people who do not have diabetes or have prediabetes. The goal is to better understand metabolic changes after the event, which could help future care.
Düsseldorf, North Rhine-WestphaliaAges 18–80 - NCT06004544Recruiting
Heart screening in pregnant women without symptoms
This study uses echocardiography (an ultrasound of the heart) to check for hidden heart problems in pregnant women who do not have any symptoms. It aims to find issues early and improve care.
Karachi, SindhAges Any age - NCT03127761Recruiting
Transplant study for Medicare patients with advanced myeloma
This study looks at outcomes of an allogeneic transplant (a donor-based transplant) in people with stage II–III multiple myeloma or primary plasma cell leukemia who have Medicare. It may help doctors better understand which patients benefit and what to expect before and after transplant.
Minneapolis, MinnesotaAges Any age - NCT05936606Recruiting
Personalized blood thinner choice after stent placement
This trial tests whether tailoring anti-platelet (blood clot prevention) treatment can better protect people at higher risk of heart or blood-vessel problems after a drug-eluting stent. It may help prevent future clots and complications, especially in patients with certain high-risk health conditions or complex stent/scar tissue features.
SeoulAges 19–80 - NCT02301663Recruiting
Stress test study of heart blood-flow issues in adults
This study tests a new kind of stress test to understand how small blood-vessel heart problems relate to heart relaxation problems in people with angina (chest pain) but no blocked arteries. It may help doctors learn better ways to diagnose and guide treatment for these conditions.
Los Angeles, CaliforniaAges 18–60 - NCT03607565Recruiting
Imaging test to measure brain blood flow in stroke
This trial studies a new imaging measurement derived from DSA (a special type of brain blood-vessel scan) to better estimate how well blood is flowing in the brain. It may help doctors assess stroke-related blood-flow problems, but it excludes people who have brain bleeding.
Xi'an, ShaanxiAges Any age - NCT00573027Recruiting
Study of heart pain from small artery heart disease
This trial studies people who have chest pain (angina) due to problems with the heart’s small arteries, not a big blockage. It aims to test whether treatment approaches can help these patients by better understanding the cause of their heart-related symptoms.
Los Angeles, CaliforniaAges 18 years+ - NCT05774288Recruiting
Testing a device to close a heart opening called PFO
This trial studies whether a Cera™ device is safe and effective for closing a patent foramen ovale (PFO), a small hole in the heart. It is for adults whose PFO is linked to certain types of stroke or ongoing clot-related events.
Beijing, Beijing MunicipalityAges 18–60 - NCT04463316Recruiting
Clinic study for people with rare genetic conditions
This study is for people who have a rare syndrome or rare congenital condition and are seen at a rare-disease clinic. It aims to better understand these conditions and how care works in a team setting, which may help guide future treatment decisions.
Rotterdam, South HollandAges 18 years+ - NCT05887440Recruiting
Isokinetic strength training for knee control after stroke
This trial studies whether a special strength-training program that uses an “isokinetic” machine can improve walking and knee control in people after stroke. It is for people who have noticeable knee movement during walking and can safely take part in rehab.
RennesAges 18–75 - NCT03793257Recruiting
ECMO patient registry for adults in Australia and New Zealand
This is a research registry for adults who need a breathing and/or heart support machine called ECMO while in the hospital. It collects information to better understand who receives ECMO and how patients do over time.
Canberra, Australian Capital TerritoryAges 18 years+ - NCT05674630RecruitingPhase 4
Drug-coated balloon for coronary artery blockages
This trial studies whether a drug-coated balloon can treat certain coronary artery narrowings in adults with chronic (long-term) coronary disease. It may help prevent re-narrowing after the procedure for people whose tests show the blockage is significant and needs treatment.
LuganoAges 18 years+ - NCT05530304Recruiting
Aortic arch stent procedure registry for adults
This study tracks outcomes after a specific aortic arch stent procedure using a device with three inner branches. It’s mainly a registry, meaning researchers follow people over time to learn how safe and effective the procedure is.
MünsterAges Any age - NCT05846321Recruiting
Registry for blood vessel injury after trauma follow-up
This study keeps a registry of adults with injuries to blood vessels caused by trauma and tracks follow-up outcomes. Your participation may help doctors better understand how these injuries heal and how to manage them.
AugsburgAges 18 years+ - NCT05891509Recruiting
DTI-guided minimally invasive surgery for deep brain bleeding
This trial studies whether a special scan-guided, minimally invasive procedure can safely remove bleeding in the basal ganglia (deep in the brain) soon after it happens. It may help patients recover better by targeting the bleeding while protecting important brain pathways.
Ganzhou, JiangxiAges 18–80 - NCT05961865Recruiting
Study of inflammation during catheter ablation for atrial fibrillation
This study measures changes in inflammation in people with atrial fibrillation (AF) who are getting a catheter ablation procedure. It may help doctors better understand what happens in the body during the procedure and why some patients do better than others.
MilanAges 18–85 - NCT00230620Recruiting
Study of inherited bleeding disorder genes in HHT families
This study looks at DNA (genetic material) in families affected by hereditary hemorrhagic telangiectasia (HHT). It aims to understand the genetic basis of HHT and why it runs in families.
LondonAges Any age - NCT04446585Recruiting
Study of early help for witnessed home cardiac arrests
This study looks at witnessed sudden cardiac arrest happening in residential areas, and tests whether a new first-responder approach gets help to people faster. It may help improve outcomes after cardiac arrest by improving the timing and coordination of emergency response.
Ballerup Municipality, The Capital RegionAges 8 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,609 recruiting cardiology studies from the U.S. registry right now, out of 14,617 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.