Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,976 recruiting studies in this area right now.
By phase
- Not applicable7,959
- Phase 2483
- Phase 4479
- Phase 3447
- Phase 1361
- Phase 1/Phase 2161
- Phase 2/Phase 386
Top conditions
- Stroke841
- Heart Failure567
- Hypertension401
- Cardiovascular Diseases390
- Coronary Artery Disease372
- Multiple Myeloma334
- Atrial Fibrillation268
- Ischemic Stroke201
- Atrial Fibrillation (AF)140
- Acute Ischemic Stroke137
- Myocardial Infarction102
- Pulmonary Hypertension100
- Congenital Heart Disease85
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California460
- Alabama197
- Massachusetts183
- Arizona174
- New York161
- Florida145
- Maryland120
- Illinois119
- Minnesota119
- Texas118
Recruiting studies9,973 total
- NCT05102019Recruiting
Device implant for severe angina using a coronary sinus reducer
This trial tests whether implanting a small device in the heart’s coronary sinus can reduce symptoms in people with long-lasting “refractory” angina despite taking the usual heart medicines. It may help improve how much activity you can do and reduce angina-related limitations.
Phoenix, ArizonaAges 18 years+ - NCT07556588Recruiting
Heart transplant study using perfusion technology
This study tests a special machine that helps preserve and evaluate donor hearts before transplant. If you're waiting for a heart transplant, this trial may help doctors find the best donor hearts and improve transplant outcomes.
LeuvenAges 18 years+ - NCT06566625Recruiting
MRI before heart catheterization for heart attack
This trial compares using a cardiac MRI before the standard catheterization (angiogram) in people with a suspected heart attack that doesn't show the typical ECG changes. It aims to see if the MRI can help guide decisions and avoid unnecessary procedures.
Stockholm, SwedenAges 18 years+ - NCT07144150Recruiting
Medicine-coated balloon for leg artery disease
This study tests a special balloon coated with medicine to open blocked leg arteries. It may help improve blood flow and reduce pain when walking or at rest.
New Haven, ConnecticutAges 18 years+ - NCT05444348Recruiting
Communication and care-planning support for blood cancer patients
This study tests an approach to help people with certain blood cancers and their main caregiver plan ahead and communicate more clearly about end-of-life care. It may help patients feel more supported and better prepared for difficult decisions.
AalborgAges 18 years+ - NCT07502599Recruiting
Fainting detection and early warning in syncope study
This study tests a new way to detect and warn about fainting in people with certain types of syncope (temporary loss of consciousness). It may help those who have already had a specific fainting evaluation called an ARS assessment.
Rochester, MinnesotaAges 18 years+ - NCT07693699Recruiting
Helping with home blood pressure monitoring in primary care
This study provides support for getting and using a home blood pressure monitor if you have high blood pressure. It tests a training pathway to help you track your blood pressure at home.
Chicago, IllinoisAges 18 years+ - NCT07659119Recruiting
Study of CT-FFR in chronic coronary syndrome patients
This study is following people with chronic coronary syndrome to see how a special CT-based blood flow test (CT-FFR) helps predict their heart health. If you have already had this test, you may be eligible to join and help doctors learn more about managing your condition.
Hangzhou, ZhejiangAges 18 years+ - NCT06153459Recruiting
Delayed cord clamping for babies with heart disease
This study looks at how long to wait before clamping the umbilical cord in babies born with a heart condition. It helps doctors understand the best timing for these newborns.
Birmingham, AlabamaAges 9 months–10 months - NCT07747025Recruiting
Nurse-led talks to help control blood pressure
This study tests whether talking with a nurse can help you manage your blood pressure better. You'll have support from a family member and learn ways to keep your blood pressure in a healthy range.
SimavAges 18 years+ - NCT07238556Recruiting
Digital tool for doctors to prescribe exercise
This trial tests a digital tool that helps doctors create personalized exercise plans for patients with heart disease risk factors. It aims to help you become more active in a safe, supported way.
Farmington, ConnecticutAges 18–64 - NCT06862583Recruiting
Study of acute type A aortic dissection treatments
This trial is studying treatments for people with a sudden tear in the main artery from the heart (type A aortic dissection) or a similar condition. It aims to improve outcomes after this emergency.
StockholmAges 18 years+ - NCT06575101Recruiting
Energy Use in Cardiac Arrest Patients During Temperature Control
This study will measure how much energy your body burns and what fuels it uses (like fat or sugar) during temperature management after a cardiac arrest. It aims to learn how to better support your recovery.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05628207Recruiting
Test of an acceptable care-scaling plan for people with brain injury
This trial looks at a care approach to see if it is acceptable and workable for adults admitted to the hospital with a traumatic brain injury. It may help improve how care is scaled and delivered after TBI.
Minneapolis, MinnesotaAges 18 years+ - NCT07256249Recruiting
Registry studying a drug-coated balloon for coronary artery disease
This trial is tracking the long-term safety and effectiveness of a sirolimus-eluting balloon (Selution SLR) in people with coronary artery disease. It aims to see how well this device works when used to open blocked arteries in real-world medical practice.
AmadoraAges 18 years+ - NCT06297291Recruiting
Long-term safety study for a kidney nerve treatment
This study tests a device that uses ultrasound to calm overactive kidney nerves, which may help lower blood pressure. It is for people with high blood pressure that is hard to control with medication.
Long Beach, CaliforniaAges 18 years+ - NCT06080074RecruitingPhase 2
Emergency heart-lung machine study for children with severe heart failure
This study tests a specific heart-lung machine called Cardiohelp to help children with severe heart failure. It looks at how well the machine works and whether a blood thinner (either heparin or bivalirudin) is safer and more effective.
Palo Alto, CaliforniaAges birth–16 years - NCT07595367RecruitingPhase 2
BBD-1 immune therapy for IgA vasculitis
This trial tests a new drug called BBD-1 that may help treat IgA vasculitis, a condition where your immune system attacks small blood vessels, causing a purple rash and organ damage. The study measures how well BBD-1 reduces symptoms and side effects.
Baltimore, MarylandAges Any age - NCT07757282Recruiting
Blood lipid (fat) levels in atrial fibrillation
This study looks at fats (lipids) in the blood of people with atrial fibrillation (an irregular heartbeat) compared to people with other heart conditions but no atrial fibrillation. The goal is to find patterns that may help understand the condition better and improve diagnosis or treatment.
Xi'an, ShaanxiAges 18 years+ - NCT07756775Recruiting
Comparing two imaging tests for stroke diagnosis
This study compares two imaging methods, magnetic resonance imaging (MRI) without contrast dye and a carotid ultrasound (Doppler), to see which one is better at finding blocked arteries in the neck that can cause strokes. The results may help doctors choose the best test for people who have had a stroke or a mini-stroke.
Sohag, Sohag GovernorateAges 18 years+ - NCT07458503Recruiting
Brain stimulation plus arm therapy for stroke recovery
This study tests a new combination treatment for people who had a stroke more than six months ago and still have arm weakness. It uses a gentle electrical current on the head (tDCS) along with a therapy that encourages use of the affected arm. The goal is to improve arm movement and daily function.
Belém, ParáAges 40–80 - NCT07758634RecruitingPhase 1/Phase 2
Study of an experimental treatment for high blood pressure
This trial tests a new treatment called CTX340 for high blood pressure that is hard to control even with multiple medications. The study aims to see if it is safe and effective.
Port Orange, FloridaAges 18–75 - NCT05638867RecruitingPhase 4
Blood thinner choice guided by risk score for heart attack patients
This trial is testing whether a newer type of blood thinner (called a NOAC) can be used safely right after a heart attack or related event, in addition to the standard two antiplatelet medicines. It focuses on patients who have higher risk signs, like elevated D-dimer levels or a higher PARIS risk score, to see if this approach is safe and effective at preventing future heart problems.
Beijing, Beijing MunicipalityAges 18–75 - NCT02257866Recruiting
Study of blood vessel inflammation over time
This study looks at different types of blood vessel inflammation (vasculitis) to learn more about why they happen and how they progress. By joining, you may help doctors better understand these conditions and improve future treatments.
Bethesda, MarylandAges 3 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,976 recruiting cardiology studies from the U.S. registry right now, out of 15,179 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Infections
- Genetic & congenital
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- Pain
- Injuries & trauma
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.