Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,609 recruiting studies in this area right now.
By phase
- Not applicable7,632
- Phase 4472
- Phase 2469
- Phase 3439
- Phase 1350
- Phase 1/Phase 2160
- Phase 2/Phase 387
Top conditions
- Stroke797
- Heart Failure534
- Hypertension388
- Cardiovascular Diseases373
- Coronary Artery Disease363
- Multiple Myeloma327
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction97
- Congenital Heart Disease84
- Peripheral Arterial Disease79
- Stroke, Ischemic78
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital68
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California453
- Alabama196
- Arizona181
- Massachusetts173
- New York168
- Florida140
- Texas122
- Maryland118
- Minnesota117
- Illinois112
Recruiting studies9,609 total
- NCT05024292Recruiting
Alliance study for acute stroke after clot removal
This trial tests a stroke treatment plan for adults after they have a clot removed by a catheter procedure (endovascular treatment). It focuses on people with certain artery blockages and specific scan results, aiming to improve recovery after successful clot removal.
Zhangzhou, FujianAges 18–95 - NCT05965115Recruiting
Screening study for family members of multiple myeloma patients
This trial screens first-degree relatives of people with multiple myeloma to check for early signs of the disease before symptoms. It may help doctors understand risk in families and find problems sooner if they occur.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT05944146Recruiting
Tests two methods for measuring heart blood flow during surgery
This trial compares a neck ultrasound test (carotid Doppler) with a heart monitoring method (thermodilution) to see if they give consistent blood-flow readings. It may help clinicians measure circulation more reliably in people having heart surgery.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT05942729Recruiting
Checking heart disease diagnosis using echo images and health data
This study looks at how well heart ultrasound (echocardiography) images and clinical information can be used to diagnose cardiac conditions. If you have a clear ultrasound study already or can get one with good image quality, your information may help improve diagnostic accuracy.
Pierre-BéniteAges 18 years+ - NCT05953558Recruiting
Study of Micra AV heart device timing in French patients
This study looks at how well a Micra AV heart device helps coordinate the heart’s timing. If you already received the Micra AV, you may be able to join as long as you consent.
ParisAges 18–110 - NCT05951517Recruiting
Mycophenolate for stubborn stomach Purpura (HSP) in children
This trial looks at whether mycophenolate mofetil can help children ages 3–18 who have Henoch-Schönlein purpura affecting the gut that does not improve with steroid treatment. It may help reduce serious stomach symptoms like severe belly pain, bleeding, or bowel problems.
Guangzhou, GuangdongAges 3–18 - NCT05701293Recruiting
RenZan stent check for leg artery narrowing
This trial follows how well the RenZan stent works and how safe it is for people with blocked or badly narrowed thigh-to-knee leg arteries. It may help by improving blood flow and adding careful monitoring to see how outcomes compare over time.
SienaAges 18 years+ - NCT05234892Recruiting
Tracking outcomes of an aortic stent graft in Italy
This study is a registry that follows people with an abdominal aortic aneurysm who are getting an Endologix Alto stent graft as planned care. It helps doctors understand how well the device works and how safely people do over time.
RomeAges 18 years+ - NCT05139589Recruiting
Collecting data from adults with heart valve infection
This study collects information about adults who are treated in Amsterdam UMC for infective endocarditis (a serious infection of the heart valves). The goal is to better understand this condition—especially for people undergoing heart valve surgery—by comparing them to similar surgery patients who do not have an infection.
Amsterdam, North HollandAges 18 years+ - NCT05960721Recruiting
Low-dose blood thinner versus standard care after heart appendage closure
This study looks at whether a lower-dose blood thinner works as well as the usual recommended anti-clot treatment after a procedure that closes off the heart’s left atrial appendage. It may help reduce bleeding risk while still preventing dangerous blood clots.
Xi'an, ShannxiAges 18 years+ - NCT03570450RecruitingPhase 1
Stem cell treatment for non-lacunar stroke after the first day
This early-phase study tests a stem cell treatment for certain types of stroke, focusing first on safety and the right dose. It may help doctors learn whether the treatment is safe and potentially beneficial when given soon after stroke begins.
GrenobleAges 18 years+ - NCT05963126Recruiting
Fetuin A test to predict kidney function decline
This study looks at a blood protein called fetuin A to see if it can forecast worsening kidney function over time in people with treated high blood pressure. It may help identify who is at higher risk for kidney decline so care can be adjusted earlier.
Ostrava, Czech RepublicAges 18–100 - NCT05958901Recruiting
Study of pulmonary hypertension in everyday clinical care
This observational study is looking at people diagnosed with pulmonary hypertension to better understand how it behaves over time. You may help researchers by allowing repeated check-ins for years and sharing symptom and test information.
Guangzhou, GuangdongAges 20–70 - NCT05962840RecruitingPhase 4
Rituximab plus telitacicept for ANCA vasculitis
This Phase 4 trial studies whether rituximab combined with telitacicept works better and is safe for people with severe active ANCA-associated vasculitis (including certain subtypes like GPA or MPA). If you meet specific blood test and disease activity criteria, you may be considered to help lower inflammation and prevent flare-ups.
BeijingAges 18–65 - NCT05970198Recruiting
Radiation with helical tomotherapy before stem cell transplant
This trial studies a specific type of radiation (helical tomotherapy) in people with multiple myeloma who are planning an autologous stem cell transplant. It may help the study team understand how safe and effective this approach is when used during transplant preparation.
Wuhan, HubeiAges 18–75 - NCT05965453Recruiting
Castor stent graft study for sudden type B aortic tears
This study looks at outcomes for people who had emergency (acute) type B aortic problems treated with a specific stent graft called the Castor single-branch device. It helps doctors understand how well this device works for selected patients and what factors affect results.
Xi'an, ShaanxiAges 18–95 - NCT05968417Recruiting
Study of new lab tests using blood or bone marrow samples for myeloma
This trial studies myeloma (and closely related blood disorders) by using extra blood or bone marrow samples for lab research. It aims to help discover new ways to understand or treat myeloma.
SuttonAges 18 years+ - NCT05965284RecruitingPhase 4
Telitacicept to help keep ANCA vasculitis in remission
This trial studies telitacicept to see if it can help keep ANCA-associated vasculitis in remission after initial treatment with steroids and rituximab. It may help prevent future flare-ups, while closely watching for side effects.
Beijing, Beijing MunicipalityAges 18–65 - NCT02670031Recruiting
Blood pressure study using heart MRI in adults
This study looks at how the heart muscle reacts in people with high blood pressure. You may have heart imaging (MRI) and blood pressure monitoring to understand patterns and potential ways to help.
SingaporeAges 21–99 - NCT05919342Recruiting
Screening for early heart failure in primary care or at home
This trial tests whether simple screening using a blood test (natriuretic peptides) plus an ultrasound of the heart (echocardiogram) can find early heart failure sooner. Finding it earlier may help doctors start the right management to prevent it from getting worse.
Cleveland, OhioAges 40 years+ - NCT04775108Recruiting
Testing a new heart procedure for severe leaking mitral valve
This trial studies a new transcatheter (through the heart without open surgery) mitral valve treatment for people with severe mitral valve leaking who are too high-risk for standard surgery. It may help reduce valve leakage and improve symptoms, but it’s an early “first-in-human” device study.
InnsbruckAges 60 years+ - NCT05563337Recruiting
Renal denervation for young women with high blood pressure
This study tests a procedure called renal denervation to help lower blood pressure in young women with high blood pressure that’s not too severe. The goal is to see if the treatment can improve blood pressure control safely.
BordeauxAges 18–40 - NCT05996211Recruiting
Swiss Study on Brain Development in Children with Heart Defects
This study follows children with severe heart problems born recently to see how their brain development progresses. It helps doctors understand what support these children might need as they grow.
BernAges 1 week–1 month - NCT05865119Recruiting
Best treatment approach for a certain heart wall defect
This study looks at the best treatment plan for people with a specific type of hole in the heart wall that affects the right side of the heart. It may help doctors choose an approach based on how well it works for patients who need treatment.
BordeauxAges 12 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,609 recruiting cardiology studies from the U.S. registry right now, out of 14,617 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
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- Mental health
- Digestive system
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- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.