Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,976 recruiting studies in this area right now.
By phase
- Not applicable7,959
- Phase 2483
- Phase 4479
- Phase 3447
- Phase 1361
- Phase 1/Phase 2161
- Phase 2/Phase 386
Top conditions
- Stroke841
- Heart Failure567
- Hypertension401
- Cardiovascular Diseases390
- Coronary Artery Disease372
- Multiple Myeloma334
- Atrial Fibrillation268
- Ischemic Stroke201
- Atrial Fibrillation (AF)140
- Acute Ischemic Stroke137
- Myocardial Infarction102
- Pulmonary Hypertension100
- Congenital Heart Disease85
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California460
- Alabama197
- Massachusetts183
- Arizona174
- New York161
- Florida145
- Maryland120
- Illinois119
- Minnesota119
- Texas118
Recruiting studies9,973 total
- NCT07639853Enrolling by invitation
Doctor feedback survey on Concerto Versa coils
This study gathers feedback from doctors who use Concerto Versa detachable coils (small metal devices that help treat brain aneurysms). The survey helps improve how these coils work and are used.
El Paso, TexasAges 22 years+ - NCT04976712Recruiting
Check body temperature in adults after out-of-hospital arrest
This trial measures core body temperature in adults who were taken to the hospital after an out-of-hospital cardiac arrest. It aims to understand temperature patterns during care, which may help guide how patients are treated after the event.
BruneckAges 18 years+ - NCT07108387RecruitingPhase 2
Stopping or reducing tocilizumab for well-controlled giant cell arteritis
This study compares stopping tocilizumab (Actemra) completely versus reducing the dose in people whose giant cell arteritis has been well controlled for at least a year. The goal is to find out which approach keeps the disease in remission while reducing medication side effects.
Atlanta, GeorgiaAges 50 years+ - NCT07754747Recruiting
Balance training after stroke
This trial compares two types of balance exercises to see which one better improves balance, posture, and reduces the risk of falling in people who had a stroke at least 6 months ago.
RawalpindiAges 40–70 - NCT07754656Recruiting
Adapted CPR study for cardiac arrest
This study tests a different way of doing CPR (cardiopulmonary resuscitation) when someone's heart stops. It aims to see if this adapted approach can improve outcomes for patients.
Linz, Upper AustriaAges 18 years+ - NCT06548204RecruitingPhase 2
Antihistamine after a heart attack
This trial tests whether taking an antihistamine medicine called fexofenadine hydrochloride can help people recover better after a heart attack. It is a randomized study, so some participants will receive the medicine and others will receive a placebo (a pill with no active ingredients).
Hangzhou, ZhejiangAges 18 years+ - NCT04991454RecruitingPhase 2
Xenon mri to image lung blood flow in pulmonary hypertension
This trial uses a special MRI scan with xenon gas to take detailed images of how blood moves through your lungs. It aims to see if this imaging can help doctors better understand and manage pulmonary hypertension, which is high blood pressure in the lungs.
Durham, North CarolinaAges 18–75 - NCT07175038RecruitingPhase 2
Study of a new pill for pulmonary hypertension
This study tests a new pill, ROC-101, for people with pulmonary hypertension (high blood pressure in the lungs). It aims to see if the pill can improve symptoms and daily function.
Phoenix, ArizonaAges 18–80 - NCT07753200RecruitingPhase 4
Comparing two blood thinners for atrial fibrillation and heart disease
This study compares two blood-thinning medicines, edoxaban and apixaban, to see which one is better at preventing strokes and bleeding in people who have both atrial fibrillation and coronary artery disease. If you're eligible, you may receive one of these standard treatments, and the trial could help find the safer option.
SeoulAges 19 years+ - NCT07754110Recruiting
A therapy for balance and coordination after stroke
This study tests a therapy called HABIT-ILE to see if it helps improve balance and coordination in people who have had a stroke. If you have had a stroke affecting one side of your body, this might help you move better.
Mansehra, KpkAges 40–60 - NCT07754188Recruiting
Comparing two treatments for unruptured brain aneurysms
This study compares two ways to treat a type of brain aneurysm (a weak spot in a blood vessel) that has not burst. It looks at early problems after using a flow diverter or stent-assisted coiling, to see which might be safer or more effective.
Guangzhou, GuangdongAges 18–75 - NCT07143019Recruiting
A new device for treating wide-necked brain aneurysms
This trial tests a special device (p48/64 MW HPC) to treat certain brain aneurysms that are wide-necked or have a shape that makes them hard to treat. It might help people with aneurysms that haven't ruptured or that have been treated before and are now coming back.
Phoenix, ArizonaAges 18 years+ - NCT05180773RecruitingPhase 4
Bromocriptine for new postpartum heart weakness
This trial studies whether bromocriptine improves health outcomes in people recently diagnosed with peripartum cardiomyopathy (a weakened heart during late pregnancy or soon after delivery). You may be asked about timing after childbirth, heart strength tests, and whether you plan to keep breastfeeding.
Birmingham, AlabamaAges 18 years+ - NCT07751432Enrolling by invitation
Improving pregnancy care in a changing climate
This study works with clinics in Dar es Salaam, Tanzania to improve pregnancy care for women living in a city, especially as the climate changes. The goal is to help keep mothers and babies healthier.
Dar es Salaam, Temeke DistrictAges 18 years+ - NCT06262789Recruiting
Returning to work after blood cancer treatment
This study helps people who have finished treatment for a blood cancer (like leukemia or lymphoma) figure out the best way to return to work. It looks at what support might be needed during this transition.
AngersAges 18–55 - NCT05976555RecruitingPhase 1
CAR T-cell therapy for relapsed myeloma after multiple treatments
This Phase 1 study tests an experimental CAR T-cell treatment that targets BCMA in people with relapsed or refractory multiple myeloma. It may help shrink the cancer after it has not responded to several prior therapies.
Milwaukee, WisconsinAges 18–80 - NCT07677410Recruiting
Aspirin alone vs. aspirin with warfarin after TAVR for aortic regurgitation
This trial tests whether taking aspirin alone is as safe and effective as taking aspirin with warfarin after a TAVR procedure for severe aortic regurgitation. It is for people who do not need long-term blood thinners for other conditions.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06704074Recruiting
Virtual Reality Training for Arm Recovery After Stroke
This trial tests whether virtual reality (VR) games and tasks can help improve arm and hand movement after a stroke. It is for people who had a first stroke 1 to 6 months ago and have some arm weakness but can sit up for 30 minutes.
Jinan, ShangdongAges 18–80 - NCT07466745Recruiting
New Pulmonary Valve Study for Kids Needing Replacement
This study tests a new type of replacement valve for children who need a new pulmonary valve (the valve between the heart and lungs). Researchers want to see if the valve works safely and well in real-world use.
Los Angeles, CaliforniaAges 1.5 years–16 years - NCT07130994Recruiting
Testing a new less invasive mitral valve replacement (SATURN)
This trial tests a new, less invasive device called the SATURN system to replace a severely leaky mitral heart valve without open-heart surgery. It is for people who are too high-risk for traditional surgery and are willing to take blood thinners.
Los Angeles, CaliforniaAges 18 years+ - NCT05195398Recruiting
Brain stimulation to improve thinking after stroke
This study tests whether a noninvasive brain stimulation treatment can improve thinking and memory problems after an acute ischemic stroke. It also uses brain scans to better understand how the treatment may help.
Baltimore, MarylandAges 18–100 - NCT07190690Recruiting
Comparing two drug-coated stents for heart attack patients
This trial compares two types of drug-coated stents (one with sirolimus, one with everolimus) in people who have had a heart attack or unstable angina and need a stent. It aims to see which stent works better for new blockages in the heart arteries.
AlicanteAges 18 years+ - NCT06844006Enrolling by invitation
How nudges help doctors prescribe heart failure medications
This study looks at whether gentle reminders (nudges) can help doctors prescribe the right heart failure medications. It aims to improve treatment for people with heart failure.
Eindhoven, North BrabantAges 18 years+ - NCT07142265Recruiting
Early inclisiran after heart attack trial
This trial tests if giving inclisiran early after a heart attack can lower cholesterol more effectively. It is for people who have had a recent heart attack and still have high LDL cholesterol despite taking statins.
CheboksaryAges 18–100
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,976 recruiting cardiology studies from the U.S. registry right now, out of 15,179 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Pain
- Injuries & trauma
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.