Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,001 recruiting studies in this area right now.
By phase
- Not applicable7,980
- Phase 2482
- Phase 4481
- Phase 3447
- Phase 1360
- Phase 1/Phase 2163
- Phase 2/Phase 388
Top conditions
- Stroke846
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation268
- Ischemic Stroke200
- Atrial Fibrillation (AF)142
- Acute Ischemic Stroke139
- Pulmonary Hypertension101
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Minnesota121
- Illinois120
- Maryland120
- Texas118
Recruiting studies9,998 total
- NCT06430632Recruiting
Early robotic walking training after stroke
This trial tests whether early, robot-assisted walking training can help people recovering from a stroke improve their ability to walk. It uses a wearable robotic exoskeleton to support your body and guide your legs during practice.
Dallas, TexasAges 18–85 - NCT06431269Recruiting
Screening for developmental disorders in children with heart disease
This study is looking for children aged 1 to 5 years who have congenital heart disease and had heart surgery or a procedure in their first year. A special nurse will check for early signs of developmental delays, to see if this kind of screening is helpful for these children.
MontpellierAges 1–5 - NCT06431711Recruiting
Eye scan study for brain small vessel disease
This study uses a special eye scan (OCTA) to check the health of tiny blood vessels in the back of the eye. It may help doctors understand small vessel disease in the brain and find easier ways to monitor it.
Hangzhou, ZhejiangAges 35 years+ - NCT06431919Recruiting
Adding statin to carvedilol for cirrhosis with heart problems
This trial tests whether adding a statin (simvastatin) to the usual heart medication carvedilol helps people with both cirrhosis and a related heart problem live longer and avoid serious liver complications.
ChandigarhAges 18–65 - NCT06433401Recruiting
Structured transition care for teens with heart disease
This study tests a structured transition care model to help teenagers with congenital heart disease move from pediatric to adult care. It aims to make the process smoother and improve your health outcomes.
Ankara, Ankara YenimahalleAges 16–20 - NCT06433947RecruitingPhase 1
Testing an experimental drug OPN-6602 for advanced multiple myeloma
This trial tests an experimental oral drug called OPN-6602 for people with multiple myeloma that has come back or stopped responding to at least three prior treatments. The main goal is to see if the drug is safe and tolerable, and to find the best dose.
Gilbert, ArizonaAges 18 years+ - NCT06434012Recruiting
Heart infection study for patients with endocarditis at Barts Heart Centre
This study gathers information from patients with a heart infection called endocarditis to help doctors better understand and treat the condition. Anyone aged 16 or older with confirmed or suspected endocarditis who is being treated at Barts Heart Centre may be able to join.
LondonAges 16 years+ - NCT06434207Recruiting
Heart defect study in newborns to understand blood clots
This study looks at tiny particles from cells in newborns with heart defects to understand blood clot risks. It aims to find ways to prevent clots after heart surgery.
Boston, MassachusettsAges 1 day–1 week - NCT06434194Recruiting
Stent study for severe leg pain or wounds
This trial tests a new stent to improve blood flow in blocked leg arteries causing severe pain or tissue loss. It may help if you have a long blockage in the upper leg but not below the knee.
New York, New YorkAges 19 years+ - NCT06435156RecruitingPhase 2
Sotagliflozin for Heart Failure in Type 1 Diabetes
This trial tests a medication called sotagliflozin for people who have both type 1 diabetes and heart failure symptoms. The goal is to see if it can improve how you feel and manage your heart and diabetes.
AberdeenAges 18–84 - NCT06435585Recruiting
Heart failure genetics and response study
This study looks at how genes affect heart failure treatment response. It uses blood samples to find new markers that may help predict who will benefit most from therapy.
StockholmAges 18 years+ - NCT06436092Recruiting
Stent treatment for left main coronary artery disease
This trial studies a new way to treat blockages in the left main coronary artery using a drug-coated stent. It aims to find out if a careful approach with a single stent and temporary side-branch support works well for people with heart disease.
Ichinomiya, Aichi-kenAges 18 years+ - NCT06437587Recruiting
Home rehab with simple tech for stroke recovery
This trial tests a home-based rehabilitation program using simple technology to help people who have had a stroke and still have trouble moving an arm or leg. It aims to see if doing exercises at home can improve your recovery.
Daqing, HeilongjiangAges 18 years+ - NCT06437600Recruiting
Immediate balloon angioplasty for severe stroke with brain artery narrowing
This trial tests whether doing an angioplasty (a procedure to open a narrowed artery with a small balloon) as soon as possible after a severe stroke caused by a blockage in a brain artery can improve recovery. It is for people who arrive within 24 hours of their stroke and have a specific type of narrowing inside the skull.
Guangzhou, GuangdongAges 18 years+ - NCT06438315Recruiting
Observational Study of Oxygen Therapy After Heart Attack
This study is looking at how well a special oxygen treatment (SSO2 therapy) works for people who have had a heart attack and received a stent in the main front artery of the heart. It aims to see if the extra oxygen helps improve recovery.
Fountain Valley, CaliforniaAges 18–80 - NCT06440083Recruiting
Predicting risk of sudden cardiac death
This study is creating a simple scoring system to predict risk of sudden cardiac arrest. It's looking for people who already have a heart condition, so the test can be made more accurate for others like you.
Guanzhou, GuangdongAges 16–90 - NCT06440317Recruiting
Study of a special filter for kidney dialysis in septic shock
This trial tests whether a special type of dialysis filter (oXiris) helps reduce blood clotting problems in patients with septic shock and kidney failure. It may offer a better option for those needing kidney support in the ICU.
PessacAges 18 years+ - NCT06440707RecruitingPhase 2
Brain stimulation for recent stroke recovery
This trial tests a safe, non-invasive brain stimulation technique called tDCS to help people recover from a recent stroke. It's for people who cannot have the standard clot-removal procedure and who can start treatment within 24 hours of their stroke.
Los Angeles, CaliforniaAges 18 years+ - NCT06441552Recruiting
How people recover after a stroke
This study follows people recovering from a first stroke or a stroke that doesn't cause new disability. The goal is to understand the natural recovery process after a stroke.
HaifaAges 18–85 - NCT06441630RecruitingPhase 3
Testing two new high blood pressure medicines together
This trial tests a combination of two new medications (AD-227A and AD-227B) to see if they work better together for people with essential (common) high blood pressure. It could be a new treatment option to help control your blood pressure.
SeoulAges 19 years+ - NCT06441760Recruiting
Telemedicine support for paramedics in children's emergencies
This study tests whether paramedics and emergency doctors can use a special video or phone link to improve care for children in emergencies. It compares the usual way doctors give advice to paramedics with a new telemedicine method.
Los Angeles, CaliforniaAges 21 years+ - NCT06441942Recruiting
Women with heart attack or unstable angina study
This study is a registry that collects information about women who have had a heart attack or unstable angina. The goal is to learn more about how these conditions affect women and improve care for women with heart disease.
Milan, Italy MilanAges 18–100 - NCT06442267RecruitingPhase 4
Comparing blood thinners for ECMO support
This trial compares three different blood thinners (heparin, argatroban, and enoxaparin) used during ECMO support. It aims to find the safest and most effective way to prevent blood clots while on ECMO.
Vienna, State of ViennaAges 18 years+ - NCT06442579Recruiting
Arm swing walking study for stroke survivors
This study looks at how a stroke affects the way your arm swings naturally when you walk. Researchers want to learn how to improve walking recovery after a stroke.
Ghent, Oost-VlaanderenAges 18–70
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,001 recruiting cardiology studies from the U.S. registry right now, out of 15,328 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.