Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,001 recruiting studies in this area right now.
By phase
- Not applicable7,980
- Phase 2482
- Phase 4481
- Phase 3447
- Phase 1360
- Phase 1/Phase 2163
- Phase 2/Phase 388
Top conditions
- Stroke846
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation268
- Ischemic Stroke200
- Atrial Fibrillation (AF)142
- Acute Ischemic Stroke139
- Pulmonary Hypertension101
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Minnesota121
- Illinois120
- Maryland120
- Texas118
Recruiting studies9,998 total
- NCT06420505Recruiting
Study of the Vivo Isar Stent in Routine Care
This trial is testing how well the Vivo ISAR stent works in everyday medical practice for people with different types of heart disease. It is for patients who need a stent for blocked arteries and are willing to receive only the Vivo ISAR stent.
Aix-en-ProvenceAges 18 years+ - NCT06420479Recruiting
How weight-loss surgery affects heart disease risk
This study looks at how weight-loss surgery (bariatric surgery) affects the chances of developing heart disease or dying early. It may help you if you have obesity but have never had heart problems or cancer before.
StockholmAges 18 years+ - NCT06420830Recruiting
Study of a new heart valve in TAVR
This study follows patients with severe aortic stenosis who get a new heart valve (the SAPIEN 3 Ultra RESILIA) through a less invasive procedure (TAVR). Researchers want to see how well this valve works over time using special heart ultrasound tests.
Québec, QuebecAges 18–80 - NCT06420752RecruitingPhase 2
Passive stretching for peripheral artery disease
This study tests whether gentle leg stretching, done by a therapist, can improve blood flow and walking ability in people with peripheral artery disease (narrowed leg arteries). It may be an option for those who cannot do regular exercise.
La Crosse, WisconsinAges 40–90 - NCT06420960Recruiting
Watch ECG vs. Holter for palpitations
This trial tests whether a special smartwatch can record heart rhythm during palpitations as well as a traditional Holter monitor. If you have unexplained palpitations and are willing to wear the watch, your participation could help doctors find better ways to diagnose heart rhythm issues.
GleizéAges 18 years+ - NCT06421025Recruiting
Blood viscosity in polycythemia patients
This study looks at how thick your blood is (blood viscosity) if you have polycythemia, a condition where your body makes too many red blood cells. It aims to understand the relationship between blood thickness and your red blood cell levels.
Pierre-Bénite, LyonAges 18 years+ - NCT06421675RecruitingPhase 2
Elranatamab for multiple myeloma that has come back
This trial tests a new drug called elranatamab (given as an outpatient, not in the hospital) for people with multiple myeloma that has come back or stopped responding to several treatments. The goal is to see if taking it less often works well and is safer.
Vancouver, British ColumbiaAges 18 years+ - NCT06422741Recruiting
Grape seed extract for cholesterol in night shift workers
This study tests whether a grape seed extract supplement can help lower LDL (bad) cholesterol in people who work rotating night shifts. It is looking for healthy adults with moderately high cholesterol who are not taking cholesterol medicine.
Reus, TarragonaAges 18 years+ - NCT06423898RecruitingPhase 4
Study on ampicillin and ceftriaxone for heart valve infection
This trial tests a combination of two antibiotics (ampicillin and ceftriaxone) to treat a heart valve infection caused by Enterococcus faecalis bacteria. It aims to see how well the medicine works and if it's safe.
AlavaAges 18 years+ - NCT06423768Recruiting
Brain MRI for cardiac arrest survivors with uncertain recovery
This study uses a special brain MRI scan to help predict recovery in people who survive a cardiac arrest but remain unconscious. It aims to give doctors and families a clearer picture of brain function when the outlook is uncertain.
Boston, MassachusettsAges 18 years+ - NCT06424119Recruiting
Intensive vs traditional cardiac rehab study
This study compares two types of cardiac rehab programs—Intensive Cardiac Rehabilitation and traditional rehab—to see which helps reduce inflammation and improve health. If you've had a recent heart event or have stable heart failure, this trial might be a good fit.
Ypsilanti, MichiganAges 18 years+ - NCT06424288RecruitingPhase 3
Testing vicadrostat plus empagliflozin for heart failure
This study tests whether adding a new study drug called vicadrostat to the standard heart failure medicine empagliflozin helps people with heart failure. It may be a good option if you have heart failure with preserved pumping function and are not already on a medicine called an MRA.
Mobile, AlabamaAges 18 years+ - NCT06424756RecruitingPhase 2
Antioxidant supplement for blood vessel health
This study tests whether an antioxidant supplement can improve blood vessel health in healthy adults. It compares the supplement's effects in non-Hispanic Black and non-Hispanic White participants to see if there are differences in how blood vessels respond.
Athens, GeorgiaAges 18–75 - NCT06424834RecruitingPhase 2/Phase 3
Targeted medicines for chest pain without blocked arteries
This study tests if specific heart medicines (like beta-blockers or calcium channel blockers) can help people with chest pain that is not caused by blocked arteries. It aims to treat the tiny blood vessels or spasms that may be the real cause of your pain.
Palo Alto, CaliforniaAges 18 years+ - NCT06424860RecruitingPhase 1
Fish Oil, Metformin and Heart Health in PCOS
This trial tests whether fish oil and metformin can improve heart health in people with PCOS who are overweight or have high blood sugar or fats. It combines two common approaches to see if they work better together.
Edmonton, AlbertaAges 25–45 - NCT06424912Recruiting
BPH treatment via vein connection for enlarged prostate
This trial tests a new treatment for enlarged prostate (BPH) that targets veins in the scrotum to improve urinary symptoms. It may be an option if you have both BPH and a varicocele and haven't had prior prostate surgery.
Panama City, Provincia de PanamáAges 40–75 - NCT06425120RecruitingPhase 4
Xuesaitong for heart disease risk factors
This trial tests whether Xuesaitong soft capsules can improve major risk factors in people with stable coronary heart disease who are already on cholesterol-lowering and antiplatelet medications. You may be able to join if you have chronic coronary artery disease and certain signs of inflammation.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06425887Recruiting
Smartwatch vs. Holter for heart rhythm detection
This study tests if a smartwatch can detect irregular heartbeats as well as a standard Holter monitor. If you have symptoms like palpitations, pre-syncope, or dizziness and are already scheduled for a Holter test, this trial may offer a simpler way to monitor your heart.
Hong KongAges 18–80 - NCT06425848Recruiting
Heart failure monitoring study
This study looks at how a small monitor inside the blood vessel to the lungs helps manage heart failure. It aims to improve care for people with advanced heart failure.
La Jolla, CaliforniaAges 18–100 - NCT06426173Recruiting
Strength training for people waiting for a heart transplant
This study tests whether resistance training (strength exercises) can help people waiting for a heart transplant. It is for patients who have been on the transplant list for less than a month and are stable enough to exercise safely.
São Paulo, São PauloAges 18–70 - NCT06427343RecruitingPhase 4
IV iron: low dose vs high dose for heart failure with low iron
This study compares two different doses of IV iron (low vs high) to see which works better for people with heart failure and low iron levels. It may help you feel less tired and breathe easier.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06427694Recruiting
Long-Term Follow-Up of Low-Dose IL-2 After Heart Attack
This study is checking on people who finished a previous trial (IVORY) that tested a low-dose treatment called IL-2 for reducing inflammation after a heart attack. It will see how they are doing over time and if the treatment helped their heart health.
Cambridge, CambridgeshireAges 18–85 - NCT06429293Recruiting
Talk therapy for PTSD and heart health
This study tests whether cognitive behavioral therapy (a type of talk therapy) can improve heart health in people with PTSD. If you have PTSD and are at risk for or have heart disease, you may be able to join.
Boston, MassachusettsAges 18–65 - NCT06429332RecruitingPhase 4
Care bundle study for brain bleed on CT scan
This trial is testing a set of standard care steps (a 'care bundle') for people who have a sudden brain bleed (intracerebral hemorrhage) that shows up on a CT scan. It aims to see if this bundle improves recovery and outcomes.
Oklahoma City, OklahomaAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,001 recruiting cardiology studies from the U.S. registry right now, out of 15,328 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
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- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.