Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,008 recruiting studies in this area right now.
By phase
- Not applicable7,984
- Phase 2484
- Phase 4481
- Phase 3449
- Phase 1360
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke846
- Heart Failure563
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease371
- Multiple Myeloma331
- Atrial Fibrillation271
- Ischemic Stroke200
- Atrial Fibrillation (AF)143
- Acute Ischemic Stroke141
- Pulmonary Hypertension101
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic84
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California467
- Alabama197
- Massachusetts182
- Arizona174
- New York163
- Florida143
- Minnesota121
- Maryland120
- Illinois119
- Texas118
Recruiting studies10,005 total
- NCT06620757Recruiting
Short-term single blood thinner after LAmbre device implant
This study tests whether it is safe and effective to use just one blood thinner (aspirin or clopidogrel) for a short time after getting a LAmbre device implanted to close off a heart pouch that can cause strokes. It is for people with atrial fibrillation who cannot take standard blood thinners long-term.
A CoruñaAges 18–100 - NCT06620705Recruiting
Pacing options for AF with low heart function
This trial compares two types of pacing for people with permanent atrial fibrillation (AF) and a weak heart pump (ejection fraction less than 50%). It tests whether pacing the left bundle branch area works as well as or better than standard biventricular pacing to improve heart function.
Aarhus N, Aarhus NAges 18 years+ - NCT06621121Recruiting
Comparing two clot-busting drugs for stroke within 4.5 hours
This study compares two medications, tenecteplase and alteplase, to see which works better at dissolving blood clots in people having an ischemic stroke. You may join if you can get treatment within 4.5 hours of when your symptoms started.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT06621264Recruiting
Exercise study to improve walking in kidney and artery disease
This trial tests whether a supervised exercise program can help people with chronic kidney disease and peripheral artery disease walk better and feel stronger. It aims to improve mobility and quality of life.
Ferrara, ItalyAges 18–80 - NCT06621407Recruiting
Best drainage method after burr hole for chronic subdural hematoma
This trial compares different ways to drain a chronic subdural hematoma after a single burr hole procedure. It aims to find which method works best to help your brain recover.
AalborgAges 18 years+ - NCT06621771Recruiting
Piano therapy for hand recovery after a first stroke
This study tests whether playing the piano (for the first time) can help improve arm and hand movement after a stroke. You would practice piano exercises to regain dexterity and coordination.
Laval, QuebecAges 40–74 - NCT06622876Recruiting
Finding unexpected blood clots in the lungs on CT scans
This study looks back at patients in the ICU who had a CT scan that unexpectedly found a blood clot in their lungs. The goal is to see how this discovery changed their treatment and what complications they may have had.
Kfar SabaAges 18–99 - NCT06622954Recruiting
Can a special diet protect the heart during breast cancer treatment?
This trial tests if a special diet can help prevent heart problems caused by chemotherapy in women with triple negative breast cancer. If you're starting a specific type of chemo, you may be able to join.
Rotterdam, South HollandAges 18–75 - NCT06623630RecruitingPhase 1
Carvykti with special radiation and chemo for kidney patients
This trial tests adding total body radiation and a chemotherapy drug (cyclophosphamide) before the standard Carvykti cell therapy for multiple myeloma patients who have kidney problems. The goal is to see if this approach is safe and effective for people with reduced kidney function.
St Louis, MissouriAges 18 years+ - NCT06624488Recruiting
Brain injury markers after cardiac arrest and outlook
This study looks at certain proteins in the fluid around the brain and in the blood after a cardiac arrest. These proteins may help doctors predict how the patient will recover, which could guide their care.
BeijingAges 18–80 - NCT06625073RecruitingPhase 4
SGLT2i for heart transplant recipients
This trial is testing a medication called SGLT2i (a type of diabetes drug that also helps the heart and kidneys) in people who have received a heart transplant. It aims to see if this drug can improve health after transplant.
Palo Alto, CaliforniaAges 18 years+ - NCT06625138Recruiting
Latex vs non-latex banding for hemorrhoids
This study compares two types of rubber bands (one made of latex, one not) used to treat internal hemorrhoids. It may help find the better option for people with grade 2-3 hemorrhoids.
Pasadena, CaliforniaAges 18 years+ - NCT06625346Recruiting
Studying Extor for new high blood pressure patients
This trial tests how well Extor (amlodipine/valsartan) works in adults who have just been diagnosed with high blood pressure and have never taken blood pressure medication. It aims to see if this combination pill helps lower blood pressure safely.
Peshawar, KPKAges 18–70 - NCT06625463Recruiting
Heart rehab at home with family support after a heart attack
This study tests a heart rehab program you can do at home, with help from your family. If you've had a heart attack in the past year and don't have other major health issues, this program might help you recover and stay healthy.
Sleman, Special Region of YogyakartaAges 18–65 - NCT06625996Recruiting
Carbs before surgery for faster recovery
This study looks at whether drinking carbohydrate-rich liquids before surgery helps you recover faster. It is for people with heart conditions, but not for those who need insulin for diabetes.
AsyutAges 18 years+ - NCT06626685Recruiting
Clonal blood cells in heart failure
This study looks at whether changes in blood cells (called clonal hematopoiesis) are linked to heart failure. By testing your blood, researchers hope to learn more about how heart failure progresses and find new ways to treat it.
BergamoAges 18 years+ - NCT06626672Recruiting
Digital Health Program for Kids with Heart Defects
This study uses digital tools to promote healthy habits in children (ages 8–14) with congenital heart disease. It aims to support both the child and their family in staying active and well.
MünchenAges 8–14 - NCT06627374Recruiting
Ultrasound to check duct closure in premature babies
This study uses ultrasound to see if a heart blood vessel called the ductus arteriosus has closed after treatment in premature infants. It aims to find a better way to monitor the response to treatment without X-rays.
Roma, romaAges Up to 4 weeks - NCT06627387Recruiting
Balance training with augmented reality for home rehab
This study tests a low-cost balance training platform that uses augmented reality to help people with balance problems from stroke or other brain conditions. It aims to see if the platform is easy and safe to use at home with a training partner.
Barcelona, BarcelonaAges 18 years+ - NCT06627751RecruitingPhase 2
Mezigdomide, Carfilzomib, and Dexamethasone for Relapsed Myeloma
This clinical trial tests a combination of three drugs—mezigdomide, carfilzomib, and dexamethasone—for people with multiple myeloma that has come back or stopped responding to prior treatments, especially when the disease has spread outside the bone (extramedullary disease). It aims to see if this new cocktail can shrink tumors and control myeloma more effectively.
Buffalo, New YorkAges 18 years+ - NCT06628271Recruiting
Breath-holding Spells Study for Young Children
This study looks at a common condition in young children called breath-holding spells. It aims to better understand how to manage these episodes, which can be scary but are usually harmless.
EslövAges birth–5 years - NCT06628531Recruiting
Lung health in patients with severe brain bleed
This trial looks at how a severe brain bleed (subarachnoid hemorrhage) might affect lung function and hyaluronic acid buildup in the lungs. It aims to find better ways to protect breathing for patients in the intensive care unit.
TianjinAges 18–80 - NCT06628973Recruiting
Social activities for women with heart failure
This trial tests a social program to help women with heart failure better stick with their medications and feel healthier. You'll be connected to community activities and support tailored to your needs.
Montreal, QuebecAges 18 years+ - NCT06629116Recruiting
Albumin treatment for large strokes after thrombectomy
This trial tests if giving a protein called albumin after a large stroke can improve recovery. Albumin may help reduce brain swelling and damage. You may qualify if you had a large stroke in the front part of the brain, got a clot-removal procedure, and meet certain age and health criteria.
Zhangzhou, FujianAges 18–80
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,008 recruiting cardiology studies from the U.S. registry right now, out of 15,355 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Blood & lymphatic
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- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.