Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,008 recruiting studies in this area right now.
By phase
- Not applicable7,984
- Phase 2484
- Phase 4481
- Phase 3449
- Phase 1360
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke846
- Heart Failure563
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease371
- Multiple Myeloma331
- Atrial Fibrillation271
- Ischemic Stroke200
- Atrial Fibrillation (AF)143
- Acute Ischemic Stroke141
- Pulmonary Hypertension101
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic84
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California467
- Alabama197
- Massachusetts182
- Arizona174
- New York163
- Florida143
- Minnesota121
- Maryland120
- Illinois119
- Texas118
Recruiting studies10,005 total
- NCT06629610Recruiting
Healthy Eating & Active Lifestyle: Yup'ik Way of Life
This trial offers a 2-year program to help Yup'ik Alaska Native communities eat healthier and be more active, based on traditional ways. It involves workshops, changes at the local food store, and community input to make healthier choices easier.
Bethel, AlaskaAges 18 years+ - NCT06629649Recruiting
AI-based glaucoma screening at health centers
This trial uses an AI tool to screen for glaucoma at community health centers. If you qualify, you will get a free eye check to catch glaucoma early and help researchers improve screening for high-risk groups.
Birmingham, AlabamaAges 18 years+ - NCT06630923RecruitingPhase 3
Preventing kidney worsening with IV albumin in heart failure
This trial tests if giving a medicine called albumin through a vein can help prevent kidney function from getting worse in people hospitalized with worsening heart failure and liver problems. It may be an option if other treatments haven't worked.
Alexandroupoli, EvrosAges 18–95 - NCT06630936Recruiting
Studying atrial fibrillation with mitral regurgitation
This trial tests a treatment for people with atrial fibrillation who also have a leaky mitral valve. It aims to see if treating both conditions together can improve symptoms.
Hangzhou, ZhejiangAges 18–80 - NCT06631157Recruiting
Essential Pro study for routine hospital patients
This trial is studying the Essential Pro device or treatment in patients who are already using it as part of their normal hospital care. The goal is to see how well it works in everyday practice.
Lai Chi KokAges 18 years+ - NCT06631378Recruiting
Groin incision direction study for vascular surgery patients
This trial compares two different ways of making an incision (cut) in the groin during blood vessel surgery. It aims to find out if one direction leads to better healing or fewer complications.
KoldingAges Any age - NCT06631534RecruitingPhase 4
Testing dexmedetomidine for kids having heart defect closure
This trial tests adding a sedative medicine called dexmedetomidine to standard anesthesia for children aged 3 to 12 who are having a procedure to close a hole in their heart (atrial septal defect). The goal is to see if it helps them recover more smoothly.
Alexandria, Alexandria GovernorateAges 3–12 - NCT06631755Recruiting
How calcium affects stent healing: an imaging study
This study looks at how calcium buildup in artery walls affects how well a stent heals. Doctors will use special imaging (OCT) right after stent placement and again a month later to check the healing of the tiny metal struts.
BarcelonaAges 18 years+ - NCT06632379RecruitingPhase 4
Atorvastatin after pregnancy to lower heart risk
This trial tests if taking atorvastatin, a common cholesterol medication, after delivery can reduce future heart problems in women who had high blood pressure or preeclampsia during pregnancy. It lasts for 6 months and includes participants who are at least 20 years old.
Columbus, OhioAges 20–50 - NCT06632587Recruiting
Early vs. late skull replacement after brain surgery
This trial compares putting the skull piece back early (around 8 weeks after the initial surgery) versus later (after 8 weeks) in people who had a hemicraniectomy for high brain pressure. The goal is to see which timing leads to better outcomes.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06632834RecruitingPhase 2
Targeted treatment study for dilated cardiomyopathy
This study tests whether a personalized treatment approach can improve heart function in people with dilated cardiomyopathy (a condition where the heart becomes enlarged and weak). It focuses on patients who still have low heart function despite standard medications.
Taipei County, Zhongzheng DistrictAges birth–99 years - NCT06633146Recruiting
Stroke rehab in nature settings
This trial tests if stroke recovery exercises in natural environments can help improve your rehabilitation. It is for people who have had a recent stroke.
LahtiAges 18 years+ - NCT06633159Recruiting
MitraClip in Patients With Heart Failure
This study looks at how well a clip (MitraClip G4) fixes a leaky heart valve in people with heart failure. If you are scheduled for this procedure, joining may help doctors learn more about the benefits of the clip.
MoscowAges 18 years+ - NCT06633809Recruiting
Treating minor stroke with large artery blockage
This study tests whether a specific treatment (likely endovascular therapy) helps people who have a minor stroke caused by a blockage in a large brain artery. If you are eligible, you may receive this treatment within 24 hours of your stroke to try to improve your recovery.
Hangzhou, ZhejiangAges 18 years+ - NCT06634121Recruiting
Comparing MitraClip and PASCAL for mitral valve repair
This trial compares two devices (MitraClip and PASCAL) for repairing a leaky mitral valve (mitral regurgitation). The goal is to see which device works better in a wide range of patients who need this type of repair.
Munich, BavariaAges 18 years+ - NCT06635187Recruiting
Oral-motor assessment and rehab app study
This study tests a mobile app that helps assess and train the muscles used for speaking and swallowing. It is for Cantonese-speaking adults who are either healthy or have had a stroke.
Hong Kong, Hong KongAges 20–85 - NCT06635551Recruiting
Comparing blood clot risks after cancer vs. non-cancer surgery
This trial studies how often blood clots form in catheters after major surgery, comparing patients with and without cancer. It may help doctors prevent clotting in the future.
Mersin, YenişehirAges 18–80 - NCT06635603Recruiting
Atmospheric pressure and hypertensive crisis study
This study looks at whether changes in atmospheric pressure (the weight of the air) are linked to very high blood pressure emergencies. You may be able to join if you come to the emergency room with a hypertensive crisis but without organ damage.
AnkaraAges 18 years+ - NCT06636175RecruitingEarly Phase 1
New imaging test for blood cancers
This study tests a new imaging agent called 64Cu-LLP2A to see if it can better detect certain blood cancers like multiple myeloma and low-grade lymphomas. It aims to find tumors more clearly than standard scans, which could help your doctor plan the best care for you.
St Louis, MissouriAges 18 years+ - NCT06636344Recruiting
Better care for people with pseudoxanthoma elasticum
This study looks at whether a new way of organizing care helps patients with pseudoxanthoma elasticum (PXE). It also asks some patients about their experience with the new care setup.
AngersAges 6 years+ - NCT06637657Recruiting
Optimizing long-term heart disease prevention
This trial tests different ways to manage and reduce the risk of future heart problems in people who have already had a heart attack or a procedure to open blocked heart arteries. The goal is to find the best long-term treatment plan to keep you healthy.
AmsterdamAges 18 years+ - NCT06637904Recruiting
TriVerity blood test for emergency patients with infection
This study tests a new blood test (called TriVerity™) that may help emergency room doctors figure out how sick you are if you have a suspected infection. If you qualify, doctors will check your blood and monitor your recovery through a short phone follow-up.
Peoria, IllinoisAges 18 years+ - NCT06638268Recruiting
TAVI for severe aortic stenosis in cardiogenic shock
This study tests whether a procedure called TAVI (a valve replacement done through a tube in the leg) can help people with severe aortic stenosis who are in cardiogenic shock, a dangerous condition where the heart can't pump enough blood. The goal is to see if urgent valve replacement improves survival.
Copenhagen OAges Any age - NCT06638385Recruiting
Space-expanding shield in stroke surgery
This trial tests a shield placed in the skull after removing a bone flap to treat swelling after a major stroke. The shield creates extra space for the brain to expand safely.
AarauAges 18–70
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,008 recruiting cardiology studies from the U.S. registry right now, out of 15,355 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
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- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.