Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,008 recruiting studies in this area right now.
By phase
- Not applicable7,984
- Phase 2484
- Phase 4481
- Phase 3449
- Phase 1360
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke846
- Heart Failure563
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease371
- Multiple Myeloma331
- Atrial Fibrillation271
- Ischemic Stroke200
- Atrial Fibrillation (AF)143
- Acute Ischemic Stroke141
- Pulmonary Hypertension101
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic84
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California467
- Alabama197
- Massachusetts182
- Arizona174
- New York163
- Florida143
- Minnesota121
- Maryland120
- Illinois119
- Texas118
Recruiting studies10,005 total
- NCT06676384RecruitingPhase 4
Testing additional drugs for IgA nephropathy in South Asian patients
This trial is testing if adding another approved drug to standard treatment can slow kidney function decline in people with IgA nephropathy. It aims to find better options for South Asian adults with this condition.
Nadiād, GujaratAges 18–65 - NCT06676553RecruitingPhase 4
Optimized kidney nerve treatment for high blood pressure
This trial tests a new way to perform a procedure called renal denervation, which uses radio waves to calm overactive kidney nerves that can raise blood pressure. By getting feedback during the procedure, doctors hope to make the treatment more effective for people with high blood pressure.
TaipeiAges 18 years+ - NCT06676904Recruiting
Platelet transfusion study for very preterm babies
This study looks at the best way to decide when to give platelet transfusions to very premature babies. It aims to help prevent bleeding while avoiding unnecessary transfusions.
Birmingham, AlabamaAges 1 hour–2 days - NCT06677970RecruitingPhase 3
Blood Pressure Control After Stroke Thrombectomy
This trial tests whether carefully lowering blood pressure after a mechanical clot removal procedure for stroke can improve outcomes. If you've had a large vessel stroke that was successfully treated with thrombectomy, this study will help guide blood pressure management in the recovery period.
Seoul, SeoulAges 20 years+ - NCT06678594Recruiting
A standardized method for treating hardened heart artery blockages
This trial is testing a new step-by-step approach (algorithm) to treat hardened, calcified blockages in heart arteries during a stent procedure. The goal is to see if this standardized method helps improve outcomes for patients with these tough-to-treat blockages.
DublinAges 18 years+ - NCT06678698Recruiting
Light therapy for blood pressure control in adults
This trial tests light therapy (photobiomodulation) to see if it helps people with high blood pressure who still have trouble controlling it with medication. It is a short study looking at an acute effect.
São Carlos, São PauloAges 40–60 - NCT06679101RecruitingPhase 3
Belantamab combination vs standard care for newly diagnosed multiple myeloma
This trial tests a new drug combination (belantamab mafodotin plus lenalidomide and dexamethasone) against the usual treatment for people newly diagnosed with multiple myeloma who cannot have a stem cell transplant. It aims to see if the new combination works better.
Mobile, AlabamaAges 18 years+ - NCT06679777Recruiting
Swedish heart and lung imaging study 2
This study invites people who already took part in the first SCAPIS study to have follow-up heart and lung imaging. It helps researchers learn how these organs change over time.
GothenburgAges Any age - NCT06679829RecruitingPhase 2
Melphalan with or without siltuximab for multiple myeloma stem cell transplant
This trial tests adding siltuximab to standard melphalan chemotherapy before a stem cell transplant. It is for people with multiple myeloma who are 60 or older and having a transplant within the first year of diagnosis.
Basking Ridge, New JerseyAges 60 years+ - NCT06680791Recruiting
Endometrial cancer study on recurrence prevention and lifestyle
This study looks at how your cancer type and daily habits might help prevent endometrial cancer from coming back. It only requires that you've had endometrial cancer and a hysterectomy.
PragueAges Any age - NCT06680869RecruitingPhase 3
Early amiodarone for shockable cardiac arrest
This trial tests whether giving the heart rhythm medicine amiodarone early after a shockable cardiac arrest improves survival. If you had a cardiac arrest due to a heart rhythm problem that didn't stop after the first shock, this study may be for you.
Portland, OregonAges 18 years+ - NCT06680986Recruiting
AI heart ultrasound study for high blood pressure
This trial uses artificial intelligence to analyze heart ultrasound images from people who had high blood pressure evaluations during a hospital stay. It aims to better understand how high blood pressure affects the heart.
Pierre-BéniteAges 18 years+ - NCT06681207Recruiting
Exploring brain stimulation for stepping after stroke
This study tests whether a mild electrical brain stimulation can help people with chronic stroke improve their stepping and walking. If you have had a stroke at least 6 months ago, can walk with or without a device, and have some leg weakness, this study may be for you.
Galveston, TexasAges 21–90 - NCT06681428Recruiting
Amniotic tissue treatment for diabetic foot ulcers
This trial tests whether an amniotic tissue treatment can help heal chronic diabetic foot ulcers that haven't improved with standard care. It focuses on a single ulcer below the ankle that has been present for more than 4 weeks but less than a year.
Fresno, CaliforniaAges 18 years+ - NCT06681506Recruiting
New heart rehab program for ischemic heart disease
This study tests a new cardiac rehabilitation treatment for people with ischemic heart disease, a condition where blood flow to the heart is reduced. The goal is to improve heart health and recovery through a structured rehab program.
Shanghai, Shanghai MunicipalityAges 18–85 - NCT06681740Recruiting
Breathing muscle training for heart disease patients
This study tests whether a special breathing exercise program can help people who have had a heart attack and a procedure to open blocked heart arteries. The exercises strengthen the muscles you use to breathe, which may improve your recovery and quality of life.
MálagaAges 18–80 - NCT06682429Recruiting
Home rehab program after stroke
This study tests a home-based therapy program delivered by video calls to help people recovering from a stroke improve arm function. It is designed for those with moderate arm weakness about 4 months after their stroke.
Downey, CaliforniaAges 18–80 - NCT06684171Recruiting
Comparing two ways to guide mitral valve clip repair
This trial tests whether using only ultrasound (echo) to guide a mitral valve clip repair is as good as using ultrasound plus X-ray. The study may help patients with a leaky mitral valve who are not good candidates for open heart surgery.
Shenzhen, GuangdongAges Any age - NCT06685042RecruitingPhase 1/Phase 2
CAR T-cell therapy for severe autoimmune diseases
This study tests a new treatment called CAR T-cell therapy for people with severe autoimmune diseases that haven't gotten better with standard treatments. The goal is to see if it can help control the disease by reprogramming your immune cells.
Rome, LazioAges 18–65 - NCT06686121RecruitingPhase 3
Improving walking after leg artery surgery for PAD
This trial tests whether drinking beetroot juice and doing home-based exercise can improve walking ability after you've had a procedure to open up blocked leg arteries. It's for people who are ready to start a walking program and want to avoid surgery.
Tucson, ArizonaAges 18 years+ - NCT06686251Recruiting
AI assistant for reading chest X-rays in breathing problems
This study tests a computer program that helps doctors read chest X-rays faster and more accurately. It is for adults who had an X-ray because of breathing problems like a cough or fever.
Curitiba, ParanáAges 18 years+ - NCT06687590Recruiting
Serranator POINT FORCE registry for leg and dialysis access
This registry study is following patients whose blocked leg or dialysis access arteries are treated with a special balloon (Serranator) that helps open the vessel. The goal is to see how well the device works in real-world use.
Scottsdale, ArizonaAges 18 years+ - NCT06688201Recruiting
Minimally invasive clot removal for large brain bleed
This trial tests a minimally invasive surgery (soft channel drainage) to remove a large blood clot deep in the brain after a stroke. It is for people who can have the procedure within 48 hours of bleeding and whose consciousness is reduced but not completely gone.
Linyi, ShandongAges 18–80 - NCT06688409Recruiting
Testing home blood pressure devices sold online
This study tests how accurate home blood pressure monitors sold online are. You may be eligible if you are already scheduled for a 24-hour blood pressure test (ABPM) and do not have certain health conditions.
Montreal, QuebecAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,008 recruiting cardiology studies from the U.S. registry right now, out of 15,355 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Injuries & trauma
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.