Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,008 recruiting studies in this area right now.
By phase
- Not applicable7,984
- Phase 2484
- Phase 4481
- Phase 3449
- Phase 1360
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke846
- Heart Failure563
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease371
- Multiple Myeloma331
- Atrial Fibrillation271
- Ischemic Stroke200
- Atrial Fibrillation (AF)143
- Acute Ischemic Stroke141
- Pulmonary Hypertension101
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic84
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California467
- Alabama197
- Massachusetts182
- Arizona174
- New York163
- Florida143
- Minnesota121
- Maryland120
- Illinois119
- Texas118
Recruiting studies10,005 total
- NCT06688396Recruiting
Finding early signs of dilated cardiomyopathy with AI and mobile screening
This trial uses a smartphone app to screen first-degree relatives of people with dilated cardiomyopathy (DCM) for early signs of the condition. It aims to detect heart muscle weakness before symptoms start, so that treatment can begin sooner.
Lancaster, PennsylvaniaAges 18 years+ - NCT06688448Recruiting
New biologic aortic valve replacement study
This study is testing a new generation of biologic (tissue) replacement valves for the aortic valve in adults aged 18 to 65. It aims to see how well these newer devices work compared to standard options.
São Paulo, São PauloAges 18–65 - NCT06689241Recruiting
Comparing blood thinners to prevent clots after weight-loss surgery
This study compares two blood-thinning medications, rivaroxaban (a pill) and enoxaparin (a shot), to prevent dangerous blood clots after weight-loss surgery. If you are scheduled for bariatric surgery, this trial could help determine which approach works better for someone like you.
AlexandriaAges 20–60 - NCT06689410Recruiting
Brain aneurysm research registry and biobank
This study is collecting medical information and samples from people with brain aneurysms to learn more about the condition. If you have a recently found aneurysm, you may be able to help researchers understand how aneurysms form and how to better treat them in the future.
Nantes, Loire-AtlantiqueAges 18 years+ - NCT06689566Recruiting
Genistein for heart attack recovery and inflammation
This study tests whether genistein, a natural compound found in soy, can help reduce inflammation and improve heart health in people who have had a heart attack and are overweight or have other risk factors.
Taipei, TaiwanAges 18 years+ - NCT06689839Recruiting
Testing a new filter to prevent stroke during heart valve replacement
This trial tests a new filter device designed to catch debris that might travel to the brain during a minimally invasive aortic valve replacement (TAVR). The goal is to see if it can help reduce the risk of stroke.
Naples, FloridaAges 50 years+ - NCT06689930Recruiting
Blood pressure app study for pregnant Black women
This study tests a mobile app (M•other App) to help pregnant Black women manage or prevent high blood pressure. You'll use the app and participate in improvement cycles with community organizations.
Madison, WisconsinAges 18 years+ - NCT06690073Recruiting
Motor relearning program for stroke recovery
This trial tests a motor relearning program to help people who had a stroke more than six months ago improve their ability to move and walk. It focuses on retraining the brain and body to work together for everyday activities.
Riyadh, Riyadh RegionAges 45–65 - NCT06690593Recruiting
Gut Microbiome Study for Healthy Adults Age 45+
This study compares the gut bacteria of healthy adults (age 45+) with those who have a blood condition called monoclonal gammopathy. The goal is to see if gut bacteria patterns differ between the two groups.
Guanzhou, GuangdongAges 45 years+ - NCT06691074Recruiting
Long-lasting CTI block with pulsed field ablation
This trial tests a new type of energy called pulsed field (gentle electrical pulses) to create a permanent block in the CTI area—a spot in the heart that can cause a fast, fluttering rhythm. It may be an option for people with both atrial fibrillation and typical atrial flutter.
Prague, PragueAges 18 years+ - NCT06691191RecruitingPhase 4
Switching to a single blood thinner after heart stent
This trial tests if people who have been on two blood thinners (aspirin plus prasugrel or ticagrelor) for at least 90 days after getting a heart stent can safely switch to just one of those blood thinners. It aims to see if taking only one pill is as safe and effective as taking two.
Jacksonville, FloridaAges 18–75 - NCT06691230Recruiting
Looking at blood flow after stroke clot removal
This study uses a special CT scan to see how well blood flows in the brain after a stroke patient has had a procedure to remove a clot. The goal is to learn more about recovery and improve future care.
BaselAges 18 years+ - NCT06692140Recruiting
Comparing two types of stents for heart artery treatment
This trial compares a newer type of stent (with very thin struts and a coating that dissolves) to a standard stent in people having a heart artery procedure. It aims to see if the new stent works as well or better.
AalborgAges 18 years+ - NCT06692504Recruiting
Blood Thinner Side Effects in the Emergency Room
This study looks at side effects of blood thinners (anticoagulants) in patients who visited the emergency department. It helps doctors understand how to better manage these medications.
BesançonAges 18 years+ - NCT06692569Recruiting
Modified physical therapy for arm and hand recovery after stroke
This study tests a type of physical therapy called modified constraint-induced movement therapy to help improve arm and hand function in people who have had a stroke more than six months ago. You will be encouraged to use your affected arm more often while the stronger arm is gently restricted, which may help retrain your brain and improve movement.
Riyadh, Riyadh RegionAges 45–65 - NCT06692751Recruiting
Eye scan for microvascular angina
This study tests if a non-invasive eye scan (OCT-A) can detect changes in tiny blood vessels in the retina of people with chest pain caused by problems with the heart's small arteries (microvascular angina). If it works, it could be a simpler way to diagnose this condition.
DijonAges 18 years+ - NCT06692855Recruiting
Frailty score's role in predicting outcomes for cardiogenic shock
This study looks at whether a simple frailty score (measuring how well someone can function) can help predict recovery for people hospitalized with cardiogenic shock, a condition where the heart suddenly can't pump enough blood.
StrasbourgAges 18 years+ - NCT06693011Recruiting
Testing the Contour device for brain aneurysms
This trial tests a device called Contour to treat a specific type of brain aneurysm (like a bubble on a blood vessel). It may be an option if you have one aneurysm that needs treatment and it fits certain size and shape requirements.
Park Ridge, IllinoisAges 18–75 - NCT06693245Recruiting
Pain during microwave treatment for varicose veins
This study looks at how much pain people feel during a microwave treatment for varicose veins in the leg. It aims to understand what factors affect pain, so the treatment can be more comfortable for future patients.
Chengdu, SichuanAges 18–90 - NCT06693180Recruiting
Hyperbaric oxygen therapy for diabetic foot ulcers
This trial is testing whether hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) can help heal diabetic foot ulcers. It is for people with diabetes who have a foot ulcer that is not healing well.
Amsterdam, North HollandAges 18 years+ - NCT06693271Recruiting
Protein, blueberries, and exercise for heart health in older adults
This trial tests whether adding protein powder, blueberries, and a gentle exercise program together can improve heart health and reduce frailty in people 65 and older.
Halifax, Nova ScotiaAges 65 years+ - NCT06693570RecruitingPhase 4
Fish skin graft for hard-to-heal leg ulcers
This trial tests whether applying a special fish skin graft, along with standard compression therapy, helps heal leg ulcers caused by poor vein function (venous leg ulcers) that have not healed with standard care alone. If you have a nonhealing venous leg ulcer, this study may offer a new treatment option.
Monroeville, PennsylvaniaAges 18 years+ - NCT06693674RecruitingPhase 3
Sacubitril-valsartan for heart health in congenital heart disease
This trial tests if a drug called sacubitril-valsartan can improve heart structure and function in adults with congenital heart disease. You will take the drug and have heart imaging to see changes.
Rochester, MinnesotaAges 18 years+ - NCT06693934Recruiting
Prevention program for young adults at risk of diabetes
This trial offers a prevention program for young adults aged 18 to 44 who have at least one risk factor for diabetes but do not already have diabetes. The program aims to help prevent or delay the onset of diabetes.
Hong KongAges 18–44
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,008 recruiting cardiology studies from the U.S. registry right now, out of 15,355 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.