Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,976 recruiting studies in this area right now.
By phase
- Not applicable7,959
- Phase 2483
- Phase 4479
- Phase 3447
- Phase 1361
- Phase 1/Phase 2161
- Phase 2/Phase 386
Top conditions
- Stroke841
- Heart Failure567
- Hypertension401
- Cardiovascular Diseases390
- Coronary Artery Disease372
- Multiple Myeloma334
- Atrial Fibrillation268
- Ischemic Stroke201
- Atrial Fibrillation (AF)140
- Acute Ischemic Stroke137
- Myocardial Infarction102
- Pulmonary Hypertension100
- Congenital Heart Disease85
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California460
- Alabama197
- Massachusetts183
- Arizona174
- New York161
- Florida145
- Maryland120
- Illinois119
- Minnesota119
- Texas118
Recruiting studies9,973 total
- NCT05953558Recruiting
Study of Micra AV heart device timing in French patients
This study looks at how well a Micra AV heart device helps coordinate the heart’s timing. If you already received the Micra AV, you may be able to join as long as you consent.
ParisAges 18–110 - NCT05875311Recruiting
Check-in monitoring for people with chronic coronary disease
This trial tests a phone/remote monitoring system to help keep regular follow-ups (“continuity of care”) for people with chronic coronary syndrome after a recent heart event. It may help your care team spot problems earlier and adjust treatment sooner.
ValenciaAges 18–72 - NCT05850416Recruiting
Caregiver partnership program for early Alzheimer or memory issues
This study tests a structured partnership with family caregivers to help manage blood pressure (especially if it’s not well controlled) in people with early Alzheimer’s disease, Alzheimer’s-related dementia, or mild cognitive impairment. It may help by improving home blood pressure monitoring and coordination between the participant and caregiver.
Minneapolis, MinnesotaAges 60–85 - NCT05741918Recruiting
Testing a monitor to measure heart output in sick children
This study checks whether a bedside “metabolic monitor” can accurately measure how well the heart is pumping (heart output) in children in the intensive care unit. It may help clinicians better understand and manage circulation using measurement methods during critical care.
MontpellierAges 4 weeks–17 years - NCT05735301Recruiting
MRI blood-flow scan-guided treatment within 6–24 hours after stroke
This trial looks at whether using an MRI blood-flow (perfusion) scan to help choose treatment improves outcomes for certain large-vessel strokes. You must be treated within 6–24 hours after symptoms start, with specific scan and blood test findings.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT05725096Recruiting
CT scan helps guide cholesterol and heart risk care
This study is testing how a special heart scan (coronary CT angiography) can help manage cholesterol levels and other heart risk factors in people who feel well and have no known heart disease. It may help doctors better decide what lifestyle or medicines you may need to lower risk.
Nanjing, JiangsuAges 40–69 - NCT05614050Recruiting
Study of outcomes after a heart stent procedure in China
This study follows people with coronary heart disease who get PCI (a procedure to open clogged heart arteries, often with a stent) and looks at their prognosis afterward. It may help researchers understand what affects recovery and outcomes after the procedure.
Wuhan, HubeiAges 18–80 - NCT05601453Recruiting
Registry for patients needing a second TAVI valve procedure
This study follows people who successfully had their first TAVI but later needed their replacement valve treated again with a “redo” TAVI. It’s mainly about tracking outcomes and safety over time to better understand who may benefit from a repeat TAVI.
GrazAges 18 years+ - NCT05595226Recruiting
Ultrasound-guided mitral valve repair to improve heart outcomes
This study looks at whether using a special heart ultrasound during surgery (called RT3D-TEE) can lead to better results for people having mitral valve repair. It’s mainly for certain types of chronic mitral valve leakage.
Beijing, Beijing MunicipalityAges 18–80 - NCT05482399Recruiting
Study statin use and silent artery plaque in older adults
This study looks at “subclinical atherosclerosis,” meaning early or silent plaque buildup in the arteries, in older people already taking statins. It may help doctors understand how well statins can slow artery damage in people with multiple health conditions.
BernAges 70 years+ - NCT05270902Recruiting
Blood-filter treatment during heart transplant surgery
This study tests whether a blood-filter treatment used during a heart transplant can improve how the transplant goes for adults. You might be eligible if you’re having a heart transplant and meet the specific medication and procedure requirements.
Vienna, State of ViennaAges 18 years+ - NCT05237232Recruiting
MRI study of blood vessel changes after ECMO in infants
This study uses a brain MRI with a special blood-vessel scan to see how circulation changes after a life-support machine called ECMO in young children. It may help doctors better understand what happens in the brain after ECMO and improve care.
ParisAges Up to 17 years - NCT05155904Recruiting
Study outcomes for adults on VA ECMO
This study looks at the results (outcomes) for adults who are receiving VA ECMO, a heart-lung life support machine. The goal is to better understand how patients do while on this type of support.
AmiensAges 18 years+ - NCT05134246Recruiting
Stent or procedure for narrowed carotid artery after neck radiation
This trial studies a carotid artery procedure (revascularization) to treat a major narrowing in the neck artery that happened after you had radiation for head or neck cancer. It may help prevent stroke risk by improving blood flow to the brain.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05092126Recruiting
Testing a pre-surgery breathing and heart check tool
This study is developing and checking how well a pre-surgery evaluation system (using objective body measurements) can predict and help around the time of anesthesia and surgery. You might be asked to complete a clinic screening and provide consent, as long as your results fit their safety and screening thresholds.
Durham, North CarolinaAges 18 years+ - NCT05022264Recruiting
Remote monitoring test during clinic visits with vital signs
This study checks how well a new device can measure vital signs (like breathing and circulation) from patients during primary or secondary care visits. It also compares the device results with standard reference methods to see if it’s safe and reliable, without causing important delays in care.
UlricehamnAges 18 years+ - NCT05020158Recruiting
Family Talk support after a serious illness in the family
This trial tests a “Family Talk” support program for families dealing with a child’s life-threatening or life-limiting illness. It aims to help families talk and cope together during the early period after diagnosis or relapse.
StockholmAges 6 years+ - NCT04780971Recruiting
Testing heart pressure measurements after a successful CTO stent
This trial studies whether special heart measurements and detailed artery scans (OCT) can better confirm how well a stent procedure worked in people with a blocked coronary artery (CTO). It may help doctors check treatment results more precisely after PCI.
NijmegenAges 18 years+ - NCT04742478Recruiting
Study of atherectomy and ultrasound for heavily calcified heart arteries
This study looks at how safe and effective a treatment is for heart artery blockages that are heavily hardened by calcium. It enrolls people who need a procedure to open the artery (with or without a stent) and whose blockage matches specific imaging or access problems.
KitakyushuAges 21 years+ - NCT04646252Recruiting
Testing a blood-surface feature to prevent heart problems
This study looks at whether a healthy blood lining (the glycocalyx) can help predict and reduce the risk of major heart events in people who have not yet had heart disease. You may be asked to do screening tests and share health information to see how these factors relate to future risk.
Athens, AtticaAges 18–85 - NCT04604418Recruiting
Tracking outcomes during non-heart procedures in children with heart defects
This study looks at how children with congenital heart disease do during routine non-heart procedures, including medical or minor treatments that are not heart-related. It also measures how much health care they use afterward, which may help improve care planning for families.
Los Angeles, CaliforniaAges Up to 21 years - NCT04327115Recruiting
Exercise program study for hospitalized adults age 75+
This study tests whether a guided physical exercise program during a short hospital stay can help older adults (75 and older) safely stay strong and move better. It may be helpful if you’re currently admitted to a geriatric short-stay unit and can safely do exercises based on your fall risk.
AngersAges 75 years+ - NCT04094428Recruiting
Study of ICU outcomes, deaths, and care costs
This study looks at what happens to people in intensive care, including deaths and hospital resource use. It may help hospitals plan better care and understand the costs of staying in the ICU.
UlmAges Any age - NCT03847025Recruiting
Lead extraction registry for pacemaker and defibrillator patients
This registry collects information from people who are having pacemaker or defibrillator leads removed. It helps doctors and researchers understand how these procedures are done and what happens afterward.
Portland, OregonAges Any age
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,976 recruiting cardiology studies from the U.S. registry right now, out of 15,179 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
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- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.