Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,609 recruiting studies in this area right now.
By phase
- Not applicable7,632
- Phase 4472
- Phase 2469
- Phase 3439
- Phase 1350
- Phase 1/Phase 2160
- Phase 2/Phase 387
Top conditions
- Stroke797
- Heart Failure534
- Hypertension388
- Cardiovascular Diseases373
- Coronary Artery Disease363
- Multiple Myeloma327
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction97
- Congenital Heart Disease84
- Peripheral Arterial Disease79
- Stroke, Ischemic78
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital68
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California453
- Alabama196
- Arizona181
- Massachusetts173
- New York168
- Florida140
- Texas122
- Maryland118
- Minnesota117
- Illinois112
Recruiting studies9,609 total
- NCT04343313Recruiting
Transcatheter repair for leaky mitral valve in high-risk adults
This pilot study tests a newer catheter-based way to reduce leakage of the mitral valve in people who feel sick from mitral regurgitation but are considered too high-risk for standard surgery. If you fit the valve and heart anatomy needs, the study may help improve symptoms and valve function without open-heart surgery.
New York, New YorkAges 21–95 - NCT06200753Recruiting
Late stroke treatment study for large vessel blockages
This study looks at patients who had an ischemic stroke (a type of stroke caused by a blood clot) more than 24 hours ago and have a blockage in a large brain artery. It compares outcomes for those who get a procedure to remove the clot versus those who get only medical treatment.
Tianjin, Tianjin MunicipalityAges Any age - NCT06204744Recruiting
Home arm and hand exercises after stroke
This trial tests a home-based exercise program for people who have weakness in one arm or hand after their first stroke. It aims to help improve movement and function without needing to go to a clinic.
Chiayi CityAges 20 years+ - NCT06191549Recruiting
Brain stimulation to improve walking after stroke
This study tests whether a non-invasive brain stimulation treatment can help improve walking ability in people who have had a stroke. It compares the effects of the treatment in stroke survivors and healthy adults to see if it can enhance recovery.
Galveston, TexasAges 21–90 - NCT07865182Recruiting
Metabolites study in spontaneous brain bleeding
This study looks at chemical byproducts in the body of people with a type of brain bleed called subarachnoid hemorrhage (SAH), which is a bleed in the space around the brain. The goal is to find patterns that might help doctors understand the condition better and improve future care.
Lisbon, Lisbon DistrictAges 18 years+ - NCT04843072Recruiting
Comparing two new valve options for a failing replacement aortic valve
This trial compares two types of replacement heart valves (balloon-expandable and self-expanding) for people whose prior surgical aortic valve is no longer working. It looks at which valve type offers better outcomes when placed through a catheter in the leg.
Los Angeles, CaliforniaAges 18 years+ - NCT07857967Recruiting
Stiff-knee walking after stroke compared with healthy walking
This study measures how thigh muscles and knee movements differ when people who had a stroke walk, compared with people without a stroke. It may help design better treatments for stiff-knee walking.
Luxembourg, LuxembourgAges 18 years+ - NCT07866859Recruiting
Leg ultrasound to predict heart pressure
This study checks if a leg ultrasound can help doctors estimate the pressure in your heart's main pumping chamber before a heart procedure. If it works, it could give useful information without extra tests.
Chon BuriAges 18–100 - NCT07864025Recruiting
Better imaging for heart artery blockages in stable angina
This study uses advanced imaging techniques to look at the build-up inside heart arteries in people with stable angina. It aims to help doctors understand and treat these blockages more accurately.
LondonAges 18–79 - NCT07856472Recruiting
AI heart test study for heart disease diagnosis
This study uses artificial intelligence to analyze heart tests (ECGs) to help diagnose and predict outcomes for people with heart disease. It may lead to better and faster detection of heart conditions.
Incheon, IncheonAges 18 years+ - NCT07855679Recruiting
Pulmonary embolism tracking from emergency care to long-term follow-up
This study follows people who have had a pulmonary embolism (a blood clot in the lungs) to understand their health over time and improve future care. It does not test a new treatment but collects information to learn more about recovery.
Bagno a Ripoli, TuscanyAges 18 years+ - NCT06045455Recruiting
CT scan to tell stroke from stroke mimics
This trial is testing whether a special type of CT scan can help doctors tell the difference between a stroke and other conditions that look like a stroke (called stroke mimics). If you have a sudden neurologic symptom within the past 24 hours, this study may help get a clearer diagnosis.
Ostrava, Moravian-Silesian RegionAges 18 years+ - NCT05694572Recruiting
Device follow-up for certain MicroPort CRM heart implants
This study checks how well specific MicroPort CRM heart devices and leads work in real life over time. If you already have one of these FDA/market-approved implants and can be followed yearly, the study helps the company monitor safety and performance.
LisbonAges 18–90 - NCT04182087Recruiting
Testing thinking skills after a localized brain injury
This trial studies how your thinking and memory abilities work after a single, localized brain injury seen on MRI. It involves cognitive (thinking) tasks to assess changes and may help researchers understand brain function after injury.
GrenobleAges 18–70 - NCT05390983Recruiting
Compare surgery vs balloon/stent for re-narrowed neck artery
This trial compares two treatments for a carotid artery that has narrowed again after a prior stent: surgery (endarterectomy) versus repeat balloon treatment with or without stenting. It may help find which approach works better to prevent further narrowing and complications.
Ostrava, Moravian-Silesian RegionAges 18–80 - NCT05978466Recruiting
Managing atrial fibrillation outcomes registry
This registry collects information on people with atrial fibrillation to understand how different treatments affect their health and quality of life over time.
Chicago, IllinoisAges 18 years+ - NCT06135909Recruiting
CHASE registry for pulmonary hypertension patients on treatment
This study is a registry that collects information on people with pulmonary hypertension who are using or starting targeted medications. The goal is to understand how these treatments work in real-world settings and improve care for patients like you.
BeijingAges 18–85 - NCT06214195RecruitingPhase 3
Shengmai San to prevent heart damage from breast cancer therapy
This trial tests if a traditional Chinese medicine called Shengmai San can protect the heart during chemotherapy and targeted therapy for HER2-positive breast cancer. Patients take the supplement alongside standard treatment to see if it reduces the risk of heart problems.
Hangzhou, ZhejiangAges 18 years+ - NCT06033014Recruiting
New decision support tool for heart disease patients
This trial tests a new decision support tool for people with ischemic heart disease (reduced blood flow to the heart). It aims to help doctors and patients make better treatment decisions. You may be able to join if you are hospitalized for various forms of heart disease and have significant blockages found during a heart catheterization.
Copenhagen ØAges 18 years+ - NCT06172842Recruiting
Heart ultrasound study for electrical rhythm problems
This study uses special ultrasound techniques to look at how the heart works in people who have heart rhythm problems caused by electrical issues, not structural ones. It aims to better understand and treat these conditions.
GuangzhouAges Any age - NCT06215625Recruiting
Smart arm rehab for stroke and spinal cord injury
This study tests a smart home-based upper limb rehabilitation program for people with stroke or spinal cord injury. It uses technology to help improve arm and hand movement.
TainanAges 20–79 - NCT05311072Recruiting
Update a CTEPH patient database in China
This study helps doctors update and improve how they understand chronic thromboembolic pulmonary hypertension (CTEPH) in patients in China. It likely involves sharing your medical information (not a new drug) and confirming your diagnosis details to support future research.
BeijingAges 14 years+ - NCT04451551Recruiting
PET/CT scan study for reduced blood flow in the heart
This study uses a special PET/CT scan that shows how well blood reaches your heart muscle. It may help doctors better assess suspected or known reduced blood flow (ischemic heart disease).
Aarhus, Aarhus NAges 18 years+ - NCT05935709Recruiting
Danish database study for GCA or PMR
This study builds and uses a Danish database for people diagnosed with giant cell arteritis (GCA) or polymyalgia rheumatica (PMR). It may help doctors learn more about these conditions over time and improve care.
AarhusAges 50 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,609 recruiting cardiology studies from the U.S. registry right now, out of 14,617 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.