Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,976 recruiting studies in this area right now.
By phase
- Not applicable7,959
- Phase 2483
- Phase 4479
- Phase 3447
- Phase 1361
- Phase 1/Phase 2161
- Phase 2/Phase 386
Top conditions
- Stroke841
- Heart Failure567
- Hypertension401
- Cardiovascular Diseases390
- Coronary Artery Disease372
- Multiple Myeloma334
- Atrial Fibrillation268
- Ischemic Stroke201
- Atrial Fibrillation (AF)140
- Acute Ischemic Stroke137
- Myocardial Infarction102
- Pulmonary Hypertension100
- Congenital Heart Disease85
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California460
- Alabama197
- Massachusetts183
- Arizona174
- New York161
- Florida145
- Maryland120
- Illinois119
- Minnesota119
- Texas118
Recruiting studies9,973 total
- NCT06705452Recruiting
MRI study of unruptured brain aneurysm growth
This study uses MRI scans to track how brain aneurysms that haven't bled change over time. It may help doctors understand which aneurysms are most likely to grow.
ReimsAges 18 years+ - NCT06329921Enrolling by invitation
Heparin monitoring study at Vanderbilt
This study looks at how well a blood test (PTT) monitors the blood thinner heparin in hospital patients. If you are getting heparin through an IV, this research may help improve how your treatment is managed.
Nashville, TennesseeAges 18 years+ - NCT06794697Recruiting
Does admission day affect anxiety before heart surgery?
This study looks at whether the day you are admitted to the hospital for planned heart surgery affects your anxiety levels before the operation. The goal is to help hospitals schedule admissions in a way that lowers stress for patients.
RennesAges 18 years+ - NCT05400174Recruiting
How blood pressure changes affect thinking and brain flow in Parkinson’s
This study measures how your blood pressure affects thinking skills and how blood flows in the brain in people with Parkinson’s. It may help researchers understand what blood-pressure changes could mean for cognition in Parkinson’s.
San Diego, CaliforniaAges 50 years+ - NCT06402968Recruiting
Clevidipine for treating high blood pressure after a brain bleed
This trial tests a blood pressure medicine called clevidipine given through an IV to people with a brain bleed (intracerebral hemorrhage). The goal is to see if quickly lowering blood pressure helps prevent more bleeding and improve recovery.
Irvine, CaliforniaAges 18–100 - NCT06626035RecruitingPhase 3
Pain Medicine Study for Children Having Heart Surgery
This study tests a pain medicine for children having heart surgery. It aims to see if the medicine works well and is safe for managing pain after the operation.
Oakland, CaliforniaAges 3–18 - NCT05092451RecruitingPhase 1/Phase 2
CD70-targeting NK cell therapy for blood cancer relapse
This study tests an immune therapy made from cord blood “NK cells” that are engineered to attack cells with a marker called CD70. It’s given after chemotherapy that reduces your blood and immune system, aiming to treat relapse or refractory (not responding) blood cancers.
Houston, TexasAges 12–80 - NCT06733935RecruitingPhase 1/Phase 2
Study of NKX019 for immune diseases
This trial tests an investigational cell therapy called NKX019 for people with certain autoimmune diseases like scleroderma, myositis, vasculitis, or rheumatoid arthritis. It aims to see if NKX019 can help control the disease when standard treatments have not worked well enough.
Orange, CaliforniaAges 18–75 - NCT07606274RecruitingPhase 1/Phase 2
Study of NVC-001 for heart muscle disease caused by LMNA gene change
This trial tests an experimental drug called NVC-001 for people with a specific genetic heart condition (LMNA-related dilated cardiomyopathy) that causes the heart to become weak and enlarged. The goal is to see if the drug can help improve heart function.
Birmingham, AlabamaAges 18 years+ - NCT07036991Recruiting
Comparing two treatments for narrowed neck arteries
This trial tests whether adding a PCSK9 inhibitor to a statin is better than a statin alone for people with mild-to-moderate narrowing of the carotid artery (the main artery in the neck). It looks at how well these treatments slow plaque buildup and prevent strokes.
ShanghaiAges 18 years+ - NCT06638073Recruiting
Continuous vitals monitoring after non-cardiac surgery
This study tests a new device that tracks your vital signs (like heart rate and oxygen levels) continuously after surgery, even when you go home. It may help doctors catch problems early and improve your recovery.
Vancouver, British ColumbiaAges 19 years+ - NCT06508697Recruiting
Heart Plaque on CT and Events After Avoiding Stenting
This study looks at how features of plaque (fatty buildup) in the heart arteries, seen on a CT scan, relate to future heart events in people who decided not to have a stent placed based on a special blood flow test (FFR). It may help doctors better understand when it's safe to avoid stenting.
Toyoake, Aichi-kenAges 20 years+ - NCT06489249RecruitingEarly Phase 1
Study on vaping, inflammation, and blood vessel health
This study looks at how vaping (e-cigarettes) might affect inflammation and blood vessel health in young adults. You will be asked to take a drug called salsalate to see if it changes these effects.
Iowa City, IowaAges 18–24 - NCT06465498Recruiting
Lung ultrasound for heart failure congestion treatment
This trial tests whether using lung ultrasound to guide decongestion treatment improves outcomes for patients hospitalized with congestive heart failure. It may help doctors tailor your care more precisely.
Geneva, Canton of GenevaAges 18 years+ - NCT06457568Recruiting
Testing a new blood pressure monitor
This study is testing a new electronic blood pressure monitor (CONTEC08C) to see how accurate it is. It is for people aged 12 to 79 who do not have heart rhythm problems, arm injuries, or other conditions that might interfere with the measurement.
Beijing, Beijing MunicipalityAges 12–79 - NCT06433115Recruiting
Lean beef and your heart and gut health trial
This study tests how eating lean beef for 4 weeks affects your heart health and the bacteria in your gut. If you qualify, you'll be asked to follow a consistent diet and activity routine during the study.
Columbia, MissouriAges 18–45 - NCT06384287Recruiting
Checking skin blood flow in ICU patients with shock
This study tests a new way to check blood flow in the tiny blood vessels of the skin for people in the ICU with circulatory failure from sepsis or heart failure. It helps doctors understand how well blood is reaching tissues, which may guide treatment.
ParisAges 18 years+ - NCT06337812Recruiting
Fiber supplement study for heart failure and diabetes
This study tests whether adding a daily fiber supplement can improve health in people with heart failure and type 2 diabetes. Participants take the supplement for several weeks to see if it helps manage symptoms and blood sugar.
Ann Arbor, MichiganAges 18 years+ - NCT06168305Enrolling by invitation
Safety and effectiveness of a GENOSS stent in multiple blocked arteries
This trial tests a new drug-coated stent (GENOSS® DES) for people with blockages in multiple heart arteries. It aims to see how safe and effective the stent is for these patients.
Seoul, SeoulAges 19 years+ - NCT06138457Recruiting
How a hands-on exam affects stress in medical students
This study looks at how a type of hands-on exam (the OSCE) affects stress levels in medical students. If you're a medical student willing to join, you can help researchers understand exam stress better.
Clermont-Ferrand, Auvergne-Rhône-AlpesAges 18 years+ - NCT06101108Recruiting
Early heart screening in back surgery patients
This trial checks people having back surgery for spinal stenosis to see if they have an early sign of heart amyloidosis (a protein buildup in the heart). The goal is to find this condition early so it can be treated before it causes problems.
BrugesAges 60 years+ - NCT06088927Recruiting
Long-term results of conduction system pacing
This study looks at how well a special type of pacemaker (conduction system pacing) works over time. If you've already had this procedure, joining could help doctors learn how to improve future care for people like you.
CaenAges 18 years+ - NCT06082856Recruiting
Dexmedetomidine for heart stability during outpatient surgery
This trial tests whether a drug called dexmedetomidine, given during general anesthesia, helps keep your heart rate and blood pressure stable during outpatient surgery. It may be an option if you are having a minor surgery and are not on certain heart medications.
NîmesAges 18 years+ - NCT06007339Recruiting
Study of a new device to close the vein after catheter procedures
This trial tests a new device called PerQseal® Elite that helps close the hole in the vein after a large catheter is used during heart or blood vessel procedures. It is for people who are already scheduled for a catheter-based procedure through a vein in the groin, and the device is designed to make the recovery easier and safer.
Rotterdam, RotterdamAges 19 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,976 recruiting cardiology studies from the U.S. registry right now, out of 15,179 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.