Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,008 recruiting studies in this area right now.
By phase
- Not applicable7,984
- Phase 2484
- Phase 4481
- Phase 3449
- Phase 1360
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke846
- Heart Failure563
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease371
- Multiple Myeloma331
- Atrial Fibrillation271
- Ischemic Stroke200
- Atrial Fibrillation (AF)143
- Acute Ischemic Stroke141
- Pulmonary Hypertension101
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic84
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California467
- Alabama197
- Massachusetts182
- Arizona174
- New York163
- Florida143
- Minnesota121
- Maryland120
- Illinois119
- Texas118
Recruiting studies10,005 total
- NCT06741436Recruiting
Exercise testing after preeclampsia
This study looks at how the heart and blood vessels work after a pregnancy complicated by preeclampsia. It uses exercise testing to see if there are lasting effects, which may help improve long-term heart health monitoring and care.
Nashville, TennesseeAges 18 years+ - NCT06741995Recruiting
Testing antibodies to predict heart muscle disease progression
This study looks at whether certain antibodies (proteins in your blood) can help predict how dilated cardiomyopathy will progress. By testing your blood, researchers hope to learn more about your condition and find better ways to manage it.
Wuhan, HubeiAges 18–75 - NCT06742125Recruiting
Drug balloon vs. stent for heart attack treatment
This trial compares two ways to treat a major heart attack: using a drug-coated balloon or a drug-eluting stent. If you are having a heart attack and need emergency angioplasty, you may qualify if your artery blockages meet specific size limits and you have no bleeding risks or allergies to the medicines used.
Hangzhou, ZhejiangAges 18 years+ - NCT06742567RecruitingPhase 3
Apixaban to prevent blood clots after a heart attack
This trial tests whether the blood thinner apixaban can prevent dangerous blood clots from forming in the heart's main pumping chamber after a specific type of heart attack. It is for patients who have severe weakness of the left ventricle and no clot already present.
Karachi, SindhAges 18–75 - NCT06742671Recruiting
Fast-track pathway for giant cell arteritis diagnosis
This trial tests a fast-track process to quickly diagnose giant cell arteritis (GCA), a condition that causes blood vessel inflammation. It may help patients get the right care faster.
La RochelleAges 50 years+ - NCT06742931Recruiting
Balloon vs stent for heart artery blockages in high bleeding risk patients
This trial compares a drug-coated balloon (medicated balloon) to a drug-eluting stent (medicated mesh tube) for treating new blockages in heart arteries. It is designed for patients with a high risk of bleeding who have completed a short course of anti-clotting medication and have been event-free for at least one year.
AnsanAges 19 years+ - NCT06743568Recruiting
Comparing new valves for tight aortic valve in enlarged aorta
This trial tests two types of replacement heart valves (self-expanding and balloon-expanding) in people who have severe aortic stenosis (tight heart valve) and an enlarged aorta (the main blood vessel from the heart). The goal is to see which valve type works better for these patients.
Beijing, Beijing MunicipalityAges 65 years+ - NCT06743789Recruiting
Radiation therapy for ventricular tachycardia: one or three sessions
This trial tests whether a single session of targeted radiation (radioablation) is as effective as three sessions for treating a dangerous heart rhythm called ventricular tachycardia in people with heart muscle disease. It's for those who continue to have episodes despite medication and catheter ablation.
New York, New YorkAges 18–90 - NCT06743711Recruiting
Heart fitness in severe mental illness study
This study checks how fit your heart and lungs are if you have a serious mental illness like schizophrenia or bipolar disorder. It aims to see if fitness can help improve health and well-being.
Glostrup MunicipalityAges 18–45 - NCT06744244Recruiting
Smell test for newborns with birth asphyxia
This study tests whether a simple smell test can help doctors better understand the risk of brain injury in newborns who had oxygen loss at birth. It may help identify babies who need extra monitoring without requiring cooling treatment.
ParmaAges 6 hours–3 days - NCT06744322Recruiting
Fast discharge after a heart attack
This trial tests if it's safe to send patients home quickly after a mild heart attack. It may help those who had a successful procedure to open a blocked artery and are stable enough to leave the hospital sooner.
Wiener Neustadt, Lower AustriaAges 18 years+ - NCT06744361RecruitingPhase 2
Ketamine after cardiac arrest to protect the brain
This trial tests whether the sedative drug ketamine, given after a cardiac arrest, can help protect the brain. It's for people whose heart stopped outside the hospital due to a shockable rhythm and who needed a breathing tube placed by emergency responders.
CopenhagenAges 18 years+ - NCT06744530Recruiting
Heart radiation therapy for ventricular tachycardia II study
This study tests if targeted radiation therapy can help people with a serious heart rhythm problem called ventricular tachycardia (VT) that hasn't gotten better with other treatments. It aims to see if this approach can reduce dangerous heart rhythm episodes.
LeuvenAges 18 years+ - NCT06745544Recruiting
Exercise program to prevent falls in older adults with diabetes
This trial tests whether a special exercise program (with music and multitasking) can help reduce falls and fractures and improve heart health in older adults with diabetes. If you are 65+ and have diabetes, you may be able to join and get free exercise classes.
Aalborg, NorhAges 65 years+ - NCT06745778Recruiting
Study of heart device signals in patients with left bundle pacing
This study looks at the electrical signals recorded by a special type of pacing lead placed in the heart's left bundle branch. It aims to understand how these signals change over time in people who already have an ICD or CRT-D device.
Wenzhou, ZhejiangAges 18 years+ - NCT06746233Recruiting
Balloon versus stent for heart attack treatment
This trial compares a drug-coated balloon to a drug-coated stent for opening blocked arteries during a heart attack. It aims to see which device works better for patients having a specific type of heart attack called STEMI.
Banja LukaAges 18 years+ - NCT06746532RecruitingEarly Phase 1
Breast milk nose drops for brain injury in newborns
This trial tests whether giving fresh breast milk as nose drops can help newborns with brain injury from lack of oxygen. It aims to see if this simple treatment can improve brain recovery.
BudapestAges Up to 2 days - NCT06747091Recruiting
Ablation study for people with persistent atrial fibrillation
This trial tests a catheter ablation procedure for people with persistent atrial fibrillation (a type of irregular heartbeat that lasts more than 7 days but less than a year). It aims to see if the procedure is safe and effective for restoring a normal heart rhythm.
Manhasset, New YorkAges 18–80 - NCT06747260RecruitingEarly Phase 1
Breast milk through the nose for HIE
This trial tests whether giving fresh breast milk through the nose is safe and possible for newborns with HIE (a brain injury from oxygen loss at birth) who are already receiving cooling therapy. It may help protect the brain and reduce injury.
BudapestAges Up to 2 days - NCT06747429Recruiting
High-fat diet for heart failure metabolism
This trial tests whether a high-fat diet can help change how your heart uses energy, potentially improving heart function in people with non-ischemic heart failure.
ParisAges 18 years+ - NCT06747689Recruiting
Sleep quality and self-care in heart failure
This study looks at how sleep quality affects the ability of people with heart failure to manage their own health. It aims to find if better sleep leads to better self-care.
IzmirAges 18 years+ - NCT06747806Recruiting
A heart surgery biobank study
This study collects tissue samples from children and adults having heart surgery. The samples will help researchers learn more about heart conditions and improve future treatments.
Hyde Park, IllinoisAges Any age - NCT06748703Recruiting
Optic nerve injury in obstructive sleep apnea patients
This study looks at whether sleep apnea affects the optic nerve, which connects your eye to your brain. It is for people newly diagnosed with sleep apnea who have not yet received treatment.
Nanjing, JiangsuAges 18–80 - NCT06749002Recruiting
Functional training for turning after stroke
This trial tests whether adding functional muscle training to turning-specific exercises helps people who have had a stroke turn more easily. It may benefit those who can walk with supervision and have no major memory or other neurological problems.
Islamabad, Punjab ProvinceAges 45–60
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,008 recruiting cardiology studies from the U.S. registry right now, out of 15,355 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.