Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,049 recruiting studies in this area right now.
By phase
- Not applicable8,023
- Phase 2486
- Phase 4480
- Phase 3451
- Phase 1361
- Phase 1/Phase 2161
- Phase 2/Phase 387
Top conditions
- Stroke854
- Heart Failure568
- Hypertension401
- Cardiovascular Diseases390
- Coronary Artery Disease372
- Multiple Myeloma330
- Atrial Fibrillation272
- Ischemic Stroke199
- Atrial Fibrillation (AF)145
- Acute Ischemic Stroke141
- Pulmonary Hypertension103
- Myocardial Infarction99
- Congenital Heart Disease86
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Massachusetts General Hospital51
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Insel Gruppe AG, University Hospital Bern50
- Johns Hopkins University47
Where studies are running
- California468
- Alabama199
- Massachusetts182
- Arizona176
- New York165
- Florida145
- Maryland120
- Minnesota120
- Illinois119
- Texas119
Recruiting studies10,046 total
- NCT06871969Recruiting
Testing a brain-wave device for stroke triage in ambulances
This trial is testing a portable EEG device (a non-invasive cap that measures brain activity) to help ambulance staff quickly determine if a patient is having a stroke. It aims to speed up diagnosis and care for people with suspected stroke symptoms.
Amsterdam, North HollandAges 18 years+ - NCT06872645Recruiting
Sodium-restricted diet for PD patients with high blood pressure
This study tests a new way to manage sodium (salt) for people on peritoneal dialysis. It aims to see if reducing sodium intake without water can help control blood pressure and improve health.
New Haven, ConnecticutAges 18 years+ - NCT06872684Recruiting
Study of a new flow diverter for brain aneurysms
This trial tests a new device called the Surpass Elite with GUARDian Flow Diverter to treat a single, unruptured brain aneurysm. If you have a wide-neck aneurysm on the internal carotid artery or its branches, this study may help determine if the device is safe and effective for you.
Tucson, ArizonaAges 18–80 - NCT06873321RecruitingPhase 4
Blood thinners after leg artery surgery to prevent clots
This trial compares two blood-thinning strategies after leg artery surgery or angioplasty to prevent dangerous blood clots. Participants will receive either rivaroxaban plus aspirin or aspirin alone, and researchers will monitor for clots over 30 days.
Pernambuco, PernambucoAges Any age - NCT06873477Recruiting
Brain injury study for children and young adults
This study looks at children and young adults who have brain damage from a severe head injury or lack of oxygen at birth. It aims to learn more about these conditions and how to help patients.
Rome, LazioAges Up to 20 years - NCT06874465Recruiting
Aortic valve replacement study for severe stenosis
This study tracks patients getting a new heart valve (transcatheter aortic valve implantation) for severe aortic stenosis. It aims to understand long-term outcomes and safety in a real-world registry.
AstanaAges 18 years+ - NCT06874556Recruiting
Paramedic support for heart failure management
This study tests if paramedics can help manage heart failure at home or in clinic, reducing hospital visits. It may be an option if you need frequent diuretic adjustments or early discharge with monitoring.
Rochester, MinnesotaAges 18 years+ - NCT06875973RecruitingPhase 3
Pelacarsen long-term extension study
This trial is for people who have already finished taking pelacarsen in a previous study. It offers continued access to the drug and checks long-term safety.
Birmingham, AlabamaAges 18–100 - NCT06876233Recruiting
Mobile app to help with blood pressure medication
This trial tests a smartphone app that sends reminders and support to help you take your blood pressure medication regularly. It may be a good fit if you have trouble remembering to take your pills.
Los Angeles, CaliforniaAges 18 years+ - NCT06876441Recruiting
Home Tai Chi Program for Heart Failure Patients and Caregivers
This study tests if a home-based Tai Chi program using a smartphone app can improve the health and well-being of people with chronic heart failure who are mostly sedentary. It also looks at how this program affects their caregivers, who will practice Tai Chi alongside them.
Qingdao, ShandongAges 18–75 - NCT06876597Recruiting
Robotic arm therapy for stroke recovery
This trial tests a robotic arm system that combines movement and thinking tasks to help people recover arm function after a first stroke. It is for people aged 40–80 who had a stroke within the last 2 weeks to 6 months and have some arm weakness but not too severe.
FuzhouAges 40–80 - NCT06876883Recruiting
Mitral regurgitation risk assessment study
This study looks at people with moderate or severe mitral regurgitation (a leaky heart valve) to better understand their risks and create models to guide treatment. It may help your doctor decide on the best care plan for you.
Guangzhou, GuangdongAges 18 years+ - NCT06876896Recruiting
Pressure inside belly during pulse field ablation for A-fib
This study looks at how pulse field ablation (a heart procedure for irregular heartbeats) affects pressure inside the belly. If you have atrial fibrillation or atrial flutter and are planning to have this procedure, your participation may help doctors understand how to make it safer.
Winston-Salem, North CarolinaAges 18 years+ - NCT06877234Recruiting
Ultrasound treatment for high blood pressure
This trial tests a new ultrasound procedure to help control high blood pressure. It's for adults whose blood pressure stays high even while taking two or more medications.
Guangzhou, GuangdongAges 18–65 - NCT06877169Recruiting
Staged heart and kidney transplant study
This study compares two ways of doing a combined heart and kidney transplant. It looks at doing the surgeries in separate stages instead of all at once, to see if that is safer or works better.
Los Angeles, CaliforniaAges 18 years+ - NCT06877221Recruiting
Ultrasound treatment for hard-to-control high blood pressure
This clinical trial tests a new procedure that uses gentle ultrasound energy to calm overactive nerves in the kidney arteries that can raise blood pressure. It is for people whose high blood pressure is not well controlled despite taking two or more medications.
GuangzhouAges 18–70 - NCT06877520Recruiting
Study of a new device for fixing leaky tricuspid valve
This trial tests a new, less-invasive device called 'Pivot Extend' for people with a severe leaky tricuspid valve (tricuspid regurgitation) who still have symptoms despite taking medicines. The goal is to see if the device can safely help reduce the leak and improve symptoms.
Tbilisi, K'alak'i T'bilisiAges 18 years+ - NCT06878105Recruiting
Blood management study for surgical patients
This study looks at how hospitals manage your blood during and after planned surgeries that have a moderate to high risk of bleeding. It aims to find better ways to reduce blood loss and the need for transfusions.
BudapestAges 18 years+ - NCT06878209Recruiting
Cough and hemorrhoids study
This study looks at how coughing may relate to hemorrhoids. Researchers want to understand the possible connection in people who have hemorrhoids but haven't had surgery for them.
Muğla, MenteşeAges 18 years+ - NCT06878677Recruiting
Personalized exercise program for stroke recovery
This study tests a personalized exercise plan designed using data from your walking and movement to help improve your recovery after a stroke.
HksarAges 45–75 - NCT06878729Recruiting
Comparing two ways to open a blocked heart artery
This trial tests two procedures—antegrade dissection/re-entry and the retrograde method—to treat a completely blocked artery. It compares which technique works better for patients with complex blockages.
Warsaw, WarsawAges 18 years+ - NCT06879379RecruitingPhase 2/Phase 3
KPD Consolidation After Stem Cell Transplant for Newly Diagnosed Myeloma
This trial tests a new way to treat multiple myeloma after a stem cell transplant. It uses a combination of drugs (KPD) to help keep the disease from coming back.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06879431Recruiting
Sleep help before heart surgery for young children
This study tests if helping babies and toddlers with sleep problems sleep better before heart surgery can lower the risk of confusion or agitation after surgery. It is for children aged 0 to 3 years who have trouble sleeping and are scheduled for heart surgery.
BeijingAges 6–12 - NCT06879561Recruiting
Wire-guided treatment for leg artery disease
This trial tests if using a special pressure-sensing wire during treatment of blocked leg arteries below the knee can improve outcomes for people with severe circulation problems that threaten the limb. It aims to help patients with Rutherford category 5 chronic limb threatening ischemia.
SeoulAges 19 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,049 recruiting cardiology studies from the U.S. registry right now, out of 15,440 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Pain
- Injuries & trauma
- Mouth & dental
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.