Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,049 recruiting studies in this area right now.
By phase
- Not applicable8,023
- Phase 2486
- Phase 4480
- Phase 3451
- Phase 1361
- Phase 1/Phase 2161
- Phase 2/Phase 387
Top conditions
- Stroke854
- Heart Failure568
- Hypertension401
- Cardiovascular Diseases390
- Coronary Artery Disease372
- Multiple Myeloma330
- Atrial Fibrillation272
- Ischemic Stroke199
- Atrial Fibrillation (AF)145
- Acute Ischemic Stroke141
- Pulmonary Hypertension103
- Myocardial Infarction99
- Congenital Heart Disease86
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Massachusetts General Hospital51
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Insel Gruppe AG, University Hospital Bern50
- Johns Hopkins University47
Where studies are running
- California468
- Alabama199
- Massachusetts182
- Arizona176
- New York165
- Florida145
- Maryland120
- Minnesota120
- Illinois119
- Texas119
Recruiting studies10,046 total
- NCT06863883Recruiting
Aortic stenosis study: looking at outcomes after TAVI
This study follows people with aortic stenosis who are getting a TAVI valve replacement. It uses imaging tests (MRI and CT) to learn more about the condition and improve future care.
GothenburgAges Any age - NCT06864234RecruitingPhase 4
Beta-blockers for chest pain without blocked arteries
This trial tests if beta-blocker medication improves blood flow and reduces resistance in the tiny blood vessels of the heart in people who have chest pain but no major blockages in their arteries.
Aalst, FlandersAges 18 years+ - NCT06864741Recruiting
Virtual reality rehab for stroke patients
This study tests whether virtual reality (VR) exercises can help people who have had a stroke recover arm movement. You will play specially designed VR games while in the hospital or at home to see if it improves your arm function.
Kentville, Nova ScotiaAges 18 years+ - NCT06865950Recruiting
Sex differences in emergency stroke care
This study looks at how men and women with suspected stroke or mini-stroke are treated by emergency services. It aims to improve care for everyone.
HomburgAges 18 years+ - NCT06866535Recruiting
Vascular infection study for patients 18 and older
This trial is studying patients with infections in blood vessels, whether natural or from a graft, to better understand and treat them.
BordeauxAges 18 years+ - NCT06866769Recruiting
Comparing imaging tests for aneurysm follow-up after EVAR
This study compares two imaging methods (CTA and CEUS) plus blood biomarkers to see which works best for monitoring your aneurysm after EVAR repair.
Valencia, ValenciaAges 18 years+ - NCT06866964RecruitingPhase 2
Aspirin to prevent blood clots in advanced germ cell cancer chemotherapy
This trial tests if daily aspirin can prevent dangerous blood clots in people receiving chemotherapy for advanced testicular or germ cell cancer. It is for those at high risk of clots and aims to improve safety during treatment.
Charlotte, North CarolinaAges 18–70 - NCT06866912Recruiting
Observational study of amyloidosis and TTR gene carriers
This study is observing people with amyloidosis or those who carry a specific gene mutation (transthyretin) to learn more about the condition. It does not test any new treatment, but may help researchers understand how the disease affects people.
BolognaAges 18–99 - NCT06867198Recruiting
Peanuts for heart, brain, and gut health
This study tests whether eating peanuts can improve health markers like blood sugar, brain function, and digestion in adults with prediabetes (higher than normal blood sugar levels). You may qualify if you are between 20-59 years old, have prediabetes, and a BMI in the overweight to obese range.
Atlanta, GeorgiaAges 20–59 - NCT06867926Recruiting
Heart rehab and its effect on DNA and inflammation
This study looks at whether a cardiac rehabilitation program can reduce DNA damage and inflammation in people with coronary artery disease. It may help patients understand how exercise and lifestyle changes can affect their heart health at a cellular level.
KayseriAges 18–65 - NCT06868069Recruiting
Blood pressure changes and frailty in older adults
This study looks at how blood pressure changes over time in older adults with high blood pressure, and how it relates to frailty (a state of increased weakness). The goal is to learn more about managing blood pressure in older people.
MilanAges 75 years+ - NCT06868823Recruiting
Blood thinners during lung transplant bypass
This study compares two different blood thinners (UFH and LMWH) used during heart-lung bypass (ECMO) for double lung transplant patients. The goal is to see which one works better and is safer.
Prague, Czech RepublicAges 18 years+ - NCT06868797Recruiting
Dapagliflozin for advanced heart failure patients waiting for transplant
This study tests whether dapagliflozin (a medicine already approved for other heart conditions) can help protect kidney and heart function in people with very advanced heart failure who are waiting for a heart transplant. If you qualify, you'll help researchers learn if this drug offers extra benefits beyond standard care.
BronAges 18 years+ - NCT06869031Recruiting
Helping rural patients manage high blood pressure with their doctor
This study tests a new way to help people with high blood pressure in rural areas manage their condition better. It focuses on improving how you and your doctor work together to keep your blood pressure under control.
Chengdu, SichuanAges 18–80 - NCT06869811Recruiting
Stroke prevention after failed blood thinners
This study is for people who had a stroke despite taking blood thinners for atrial fibrillation. It tests if adding a procedure to close the left atrial appendage (a small pouch in the heart) to your blood thinner is better than just taking the blood thinner alone to prevent another stroke.
Barcelona, BarcelonaAges 18–95 - NCT06869954Recruiting
Bicuspid aortic valve repair: comparing two surgical techniques
This trial tests two different ways to repair a leaky bicuspid aortic valve (a valve with two flaps instead of three). The goal is to see which repair method works better. If you need surgery for a severely leaking valve and your valve is the right shape, you may be able to join.
Augsburg, BavariaAges 18 years+ - NCT06870175Recruiting
Smart shirt heart monitoring trial
This trial tests a smart textile ECG monitor worn as a shirt to track your heart rhythm for up to 14 days. It may replace the usual sticky electrodes and wires, making monitoring more comfortable.
Newmarket, OntarioAges 18 years+ - NCT06870409RecruitingPhase 3
Phages plus antibiotics for heart infection treatment
This trial tests if adding bacteriophages (viruses that kill bacteria) to standard antibiotic treatment can help people with a serious heart valve infection called infective endocarditis. It may offer a new way to fight the infection.
MoscowAges 18 years+ - NCT06870591Recruiting
Heart measurement device study
This trial tests a new device that measures heart function without needing an invasive catheter. It aims to see if the device works as well as the standard right heart catheterization procedure.
Huntsville, AlabamaAges 18 years+ - NCT06871228Recruiting
Stopping blood thinners after successful AF ablation with close heart monitoring
This trial tests whether people with atrial fibrillation who have had a successful ablation procedure can safely stop taking blood thinners (NOACs) if they wear a monitor to check for any silent heart rhythm problems. It may help you avoid the risks of long-term blood thinner use if your ablation has been effective.
Hefei, AnhuiAges 18–80 - NCT06871176Recruiting
New PET/MR scan vs standard imaging for multiple myeloma
This trial compares a new type of PET/MR scan (using a radioactive tracer called Ga-68 PentixaFor) with standard imaging to see if it can better detect multiple myeloma at diagnosis and during follow-up. It may help improve staging and treatment planning.
Toronto, OntarioAges 18 years+ - NCT06871293Recruiting
Long Covid recovery: rehab with coaching
This study tests a program of rehab exercises and memory/thinking activities, along with coaching messages, to help people with Long Covid feel better and function in daily life. You may qualify if you had Covid, have high blood pressure or diabetes, and still have symptoms like fatigue or trouble thinking for at least 4 weeks.
Bogotá, Bogotá DCAges 18–80 - NCT06871774Recruiting
One vs. two closure devices for TAVR access site
This trial compares using one versus two Perclose devices to close the large hole in the leg after a TAVR procedure. It aims to find which method works better to prevent bleeding and other complications.
Milwaukee, WisconsinAges 18 years+ - NCT06871800Recruiting
Blood tests to predict recovery after stroke or brain injury
This study looks at tiny particles in your blood called extracellular vesicles to see if they can help predict how well you will recover after a stroke or brain injury. If you are starting rehabilitation soon after your stroke, you may be able to join.
FlorenceAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,049 recruiting cardiology studies from the U.S. registry right now, out of 15,440 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Infections
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- Pain
- Injuries & trauma
- Mouth & dental
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.