Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,973 recruiting studies in this area right now.
By phase
- Not applicable7,957
- Phase 2481
- Phase 4480
- Phase 3447
- Phase 1360
- Phase 1/Phase 2162
- Phase 2/Phase 386
Top conditions
- Stroke843
- Heart Failure565
- Hypertension399
- Cardiovascular Diseases390
- Coronary Artery Disease373
- Multiple Myeloma333
- Atrial Fibrillation268
- Ischemic Stroke200
- Atrial Fibrillation (AF)140
- Acute Ischemic Stroke138
- Myocardial Infarction101
- Pulmonary Hypertension100
- Stroke, Ischemic86
- Congenital Heart Disease85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California461
- Alabama197
- Massachusetts183
- Arizona173
- New York161
- Florida145
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,970 total
- NCT06975111RecruitingPhase 2/Phase 3
Improving health during menopause
This trial studies ways to help women during the late menopausal transition. It uses a smartphone app and telehealth visits to track your health and help you feel better.
Aurora, ColoradoAges 45–55 - NCT06967441Recruiting
Respiratory viruses and acute heart failure study
This trial looks at whether a respiratory virus might be triggering your heart failure. It will test your nasal swab for viruses to help doctors understand and treat your condition better.
Seongnam-si, Gyeonggi-doAges 19 years+ - NCT06907186Recruiting
Psychological support program for amyloidosis patients and families
This study tests a structured psychological support program for people with hereditary transthyretin amyloidosis (ATTRv) with heart involvement, their caregivers, and those who carry the gene but have no symptoms yet. The goal is to see if the program is practical and well-accepted.
PaviaAges 18 years+ - NCT06918301Recruiting
Comparing heart measurements in cardiac surgery patients
This trial compares three ways to measure how well your heart pumps blood after cardiac surgery. It uses a standard catheter and two newer monitors to see which is most accurate.
KarlsburgAges 18 years+ - NCT06943365Recruiting
Role of Anti-TREK-1 Antibodies in Sudden Cardiac Arrest Without Blockage
This study looks for a specific type of antibody (called anti-TREK-1) in the blood of people who have had a sudden cardiac arrest without a clear cause. It aims to understand if these antibodies play a role in the condition, which might help with future diagnosis or treatment.
Vancouver, British ColumbiaAges 18 years+ - NCT06840327Recruiting
Oxygen levels during heart bypass surgery and recovery
This study looks at how different oxygen levels during heart bypass surgery might affect recovery. It aims to see if keeping oxygen at a certain level can improve outcomes for people having surgery where a vein from the leg is used to bypass a blocked heart artery.
ToulouseAges 18 years+ - NCT06823778Recruiting
Preventing irregular heartbeat after heart surgery with radiofrequency
This trial tests whether using radiofrequency energy to isolate a small area in the heart's left upper chamber can prevent a common irregular heartbeat (atrial fibrillation) after heart surgery.
Moscow, MoscowAges 18 years+ - NCT06836531Enrolling by invitation
Quick blood test for heart attack drug levels
This trial is testing a new way to quickly measure the level of a blood thinner (tirofiban) in the blood of people having a heart attack. It aims to make sure the dose is right and safe for each patient.
Ningbo, ZhejiangAges 18–75 - NCT06832644Recruiting
Heart risk prediction study for healthy adults in Italy
This study tests a new way to predict your future risk of heart disease. It is for healthy adults aged 40-80 who have never had heart problems or diabetes. You will use your email and internet to take part.
Milan, MilanAges 40–80 - NCT06861361Recruiting
Surgery versus transcatheter valve replacement in younger patients
This trial compares two ways to replace a narrowed aortic heart valve in patients aged 65 to 75. It aims to find which approach—surgical valve replacement or a catheter-based procedure—works better for people in this age group.
GrazAges 65–75 - NCT06879769Recruiting
Better heart CT scan preparation study
This study looks at how to improve the preparation and imaging techniques for heart CT scans. It may help make the scan more comfortable and accurate for people who already have a heart CT scheduled.
Stockholm, HuddingeAges 18 years+ - NCT06716840Recruiting
Remimazolam for sedation after heart surgery
This trial tests a medication called Remimazolam Besylate to sedate patients who need a breathing tube after heart surgery. The goal is to help patients relax while they recover in the intensive care unit.
Hangzhou, ZhejiangAges 18 years+ - NCT06786728Enrolling by invitation
Ultrasound-guided fluid removal for kidney recovery in heart-kidney syndrome
This study tests if using ultrasound scans to guide fluid removal helps protect kidney function in people with cardiorenal syndrome type 1, where heart failure suddenly worsens kidney function.
CairoAges 18–65 - NCT06770543Recruiting
Study of Leqvio for high cholesterol in Korea
This study is for adults in Korea with high cholesterol who need a new option because statins aren't working well enough or cause side effects. It will look at how well the medication Leqvio works in everyday medical practice.
Yangsan, Gyeongsangnam-doAges 18–100 - NCT06743269Recruiting
Breathing Training for Stress and Sleep in Midlife Women
This study tests a simple breathing exercise (inspiratory muscle strength training) to see if it can help reduce stress and improve sleep for midlife women who have hot flashes. If you're between 45-60, have hot flashes, and don't smoke, you may be able to join.
Rochester, MinnesotaAges 45–60 - NCT06723145RecruitingPhase 4
Perioperative antiplatelet therapy for abdominal surgery after stent
This study looks at the best way to manage your blood-thinning medicine (antiplatelet therapy) around the time of abdominal surgery, if you have a coronary stent. The goal is to help reduce the risk of heart problems while keeping bleeding risks low.
KyotoAges 20 years+ - NCT06791850Recruiting
Home heart failure support for rural patients and caregivers
This trial tests a home-based palliative care program for people with advanced heart failure living in rural areas and their caregivers. It aims to improve quality of life and reduce symptoms.
Morgantown, West VirginiaAges 45–80 - NCT06686615Recruiting
Study of a triple cholesterol medicine combination in high-risk patients
This study tests a cholesterol-lowering combination of three medicines: bempedoic acid, ezetimibe, and a statin (atorvastatin or rosuvastatin). It is for people with high cholesterol, especially those at high risk for heart problems, who need stronger treatment.
Braunau am InnAges 18 years+ - NCT06794359Enrolling by invitation
Comparing minimally invasive vs. traditional bypass for multi-vessel heart disease
This study compares two types of heart bypass surgery for people with blockages in multiple heart arteries: a newer, less invasive technique (minimally invasive CABG) versus the traditional open-chest approach. It aims to see which approach leads to better recovery and outcomes.
São Paulo, São PauloAges 18 years+ - NCT06692218Recruiting
Leadless pacemaker placement and its effect on procedure success
This study looks at where doctors place small, wire-free pacemakers and how that affects the safety and success of the procedure. It includes people who are about to get a leadless pacemaker or have had one since 2015.
Hong KongAges 18 years+ - NCT06674616Enrolling by invitation
Heart health program for community mental health staff
This trial tests a program to improve heart health in community mental health settings. Staff members will be trained to deliver the program and help reduce health disparities.
Baltimore, MarylandAges 18 years+ - NCT06663267Recruiting
Weather and air pollution effects on heart health
This trial looks at how weather and air pollution may impact your heart health. It uses medical records to study these effects.
Hanzhou, ZhejiangAges 18–75 - NCT06629077RecruitingPhase 2
Brain blood vessel response to blood flow changes
This study looks at how blood vessels in the brain react when blood flow changes. It may help researchers understand how the brain adapts with age.
Madison, WisconsinAges 55–69 - NCT06656117Enrolling by invitation
Elliptical vs. resistance training for heart bypass recovery
This study compares elliptical training with resistance training to see which better improves heart and lung function in patients who have had coronary artery bypass grafting (CABG). It aims to help you recover more fully during phase III cardiac rehab.
Sialkot, Punjab ProvinceAges 45–55
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,973 recruiting cardiology studies from the U.S. registry right now, out of 15,205 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.