Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,973 recruiting studies in this area right now.
By phase
- Not applicable7,957
- Phase 2481
- Phase 4480
- Phase 3447
- Phase 1360
- Phase 1/Phase 2162
- Phase 2/Phase 386
Top conditions
- Stroke843
- Heart Failure565
- Hypertension399
- Cardiovascular Diseases390
- Coronary Artery Disease373
- Multiple Myeloma333
- Atrial Fibrillation268
- Ischemic Stroke200
- Atrial Fibrillation (AF)140
- Acute Ischemic Stroke138
- Myocardial Infarction101
- Pulmonary Hypertension100
- Stroke, Ischemic86
- Congenital Heart Disease85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California461
- Alabama197
- Massachusetts183
- Arizona173
- New York161
- Florida145
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,970 total
- NCT06629311Recruiting
Blood recycling device study in heart surgery
This trial looks at how a device that collects and reuses your own blood during heart surgery works. It may help reduce the need for donated blood.
Strasbourg, Bas-RhinAges 18 years+ - NCT06618248Recruiting
Sirolimus balloon for heart artery blockages at branches
This study tests a balloon coated with sirolimus (a medicine to prevent re-narrowing) to treat blockages in branch arteries of the heart. It may help patients who need a stent in the main artery but have a side branch that can be treated with this balloon instead of a stent.
Beijing, Beijing MunicipalityAges 18–85 - NCT06795958Recruiting
Detecting heart rejection without a biopsy in children
This trial tests if a special MRI can detect early signs of heart rejection in children and young adults who have had a heart transplant. If successful, it might reduce the need for invasive biopsies.
BolognaAges Up to 18 years - NCT06588777Recruiting
Two Nerve Blocks for Pain After Gallbladder Surgery
This study compares two types of nerve blocks for pain relief after laparoscopic gallbladder surgery. If you take part, you will receive either an ultrasound-guided M-TAPA block or a quadratus lumborum block, and the researchers will measure how well each controls your pain.
CairoAges 21–71 - NCT06616129Recruiting
Geriatric risk assessment for older heart surgery patients
This study tests whether a special geriatric risk assessment and shared decision-making conversation helps older patients (70+) and their doctors choose the best treatment for heart surgery. It aims to improve quality of life by tailoring decisions to each person's health risks.
Groningen, Provincie GroningenAges 70 years+ - NCT06656832Recruiting
How Heart Failure Progresses in Hospitalized Patients
This study looks at why heart failure gets worse over time. It involves people who have been hospitalized for heart failure and have a known heart abnormality. Doctors will monitor your health to find clues about disease progression.
LeipzigAges 18 years+ - NCT06689111Recruiting
Heart resynchronization method study for patients with LBBB and heart failure
This study compares two ways to resynchronize the heart's pumping in people with heart failure and a specific heart block (LBBB). It uses special ultrasound imaging to see which method works better for improving heart function.
Pátrai, GreeceAges 18–90 - NCT06659393Recruiting
Entresto in children with chronic heart failure
This study is for children with chronic heart failure who are starting Entresto for the first time. It helps doctors learn how well the medicine works and how safe it is for kids.
Ōbu, Aichi-kenAges 1–17 - NCT06652425Recruiting
How cold affects the heart and blood vessels
This study looks at how brief cold exposure affects the heart and blood vessels in healthy adults. It may help us understand the body's response to cold and its potential health impacts.
Shanghai, Shanghai MunicipalityAges 18–30 - NCT06683118Enrolling by invitation
Drug-coated balloon for blocked brain arteries
This trial tests whether a drug-coated balloon can safely open a severely blocked brain artery (at least 70% blocked) that remains symptomatic despite medication. It is designed for people who have not had a recent stroke or other major health problems.
Beijing, Beijing MunicipalityAges 18–80 - NCT06523738Recruiting
Studying heart size changes after shock and ablation for AF
This trial looks at how the size of your heart's upper-left chamber (left atrium) changes after a procedure to restore a normal rhythm (cardioversion). It aims to see if these changes can predict whether atrial fibrillation (AF) will come back after a later procedure called radiofrequency ablation.
Chongqing, Chongqing MunicipalityAges 18 years+ - NCT06514820Recruiting
Exercise MRI study for obesity-related heart failure
This study uses an exercise test with MRI to understand how obesity affects the heart in people with heart failure. It aims to find better ways to diagnose and help patients.
GroningenAges 18 years+ - NCT06577038Enrolling by invitation
Registry for a new heart artery treatment
This study tracks how well a new treatment called intravascular lithotripsy works for opening up hardened heart arteries. If you're having this procedure, joining the registry helps doctors learn more about its benefits.
BrusselsAges 18 years+ - NCT06544954Recruiting
Grape study for heart and gut health in overweight women
This study tests whether eating California grapes can improve gut health and heart health in overweight or obese women who have been through menopause and may have type 2 diabetes or metabolic syndrome. You would need to eat grapes daily and provide blood and stool samples.
Davis, CaliforniaAges 45–70 - NCT06538831Recruiting
Ultra-processed foods and heart health
This study looks at how eating ultra-processed foods (like packaged snacks and sugary drinks) affects heart health markers such as cholesterol and blood pressure. If you are generally healthy and have a stable weight, you may be able to join.
Québec, QuebecAges 18–75 - NCT06557707Recruiting
Stress and heart health in young people
This study looks at how early life stress affects heart health in young people. It compares two age groups to see how stress early in life might influence cardiovascular risk.
Richmond, VirginiaAges 9–30 - NCT06516432Recruiting
Nerve block and lactate in heart surgery
This study looks at how a nerve block near the breastbone (parasternal block) affects lactate levels in the blood for patients having heart surgery. It aims to understand if this pain management technique can help keep lactate levels normal during recovery.
Guadalajara, JaliscoAges 18 years+ - NCT06585462RecruitingPhase 1
Study of AMG 513 for people with obesity
This study tests an experimental medication called AMG 513 to see how safe it is and how the body processes it. It is for people with obesity who may benefit from a new treatment option.
Anaheim, CaliforniaAges 18–65 - NCT06520982RecruitingEarly Phase 1
Early brain and blood vessel changes in aging women
This study looks at how blood vessels in the brain change as women age. It may help understand why some women have higher risk for certain health problems later in life.
Columbia, MissouriAges 18–70 - NCT06577688Recruiting
Checking blood pressure with a smartphone app
This trial tests whether a smartphone app can accurately measure your blood pressure without a cuff. It may help find people with high blood pressure early using only a phone.
Lausanne, Canton of VaudAges 18–80 - NCT06591000Recruiting
Comparing two types of tricuspid valve replacements
This trial compares two types of replacement valves for the tricuspid valve: a donated human valve (allograft) and a stented biological valve (made from animal tissue). The goal is to see which works better and lasts longer.
ChelyabinskAges 18–70 - NCT06482476Recruiting
Medical students' knowledge of cholesterol and lipoprotein(a)
This study asks medical students in Greece to share their understanding of high cholesterol and a related blood fat called lipoprotein(a). It helps researchers learn what future doctors know about these conditions.
Ioannina, IoanninaAges Any age - NCT06454396Recruiting
Treating blocked dialysis fistulas from inside the blood vessel
This trial tests a new way to reopen blocked or narrowed fistulas (the blood vessels used for dialysis) in people on hemodialysis. The goal is to see how well it works and if it saves money compared to other treatments.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06449092Recruiting
Remnant Cholesterol and Neck Artery Thickness in Fatty Liver
This study looks at whether a type of cholesterol called 'remnant cholesterol' and the thickness of the carotid artery (a neck artery) are linked to fatty liver disease. It may help doctors find better ways to prevent heart problems in people with fatty liver.
AsyutAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,973 recruiting cardiology studies from the U.S. registry right now, out of 15,205 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
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- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
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- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
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- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.