Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,609 recruiting studies in this area right now.
By phase
- Not applicable7,632
- Phase 4472
- Phase 2469
- Phase 3439
- Phase 1350
- Phase 1/Phase 2160
- Phase 2/Phase 387
Top conditions
- Stroke797
- Heart Failure534
- Hypertension388
- Cardiovascular Diseases373
- Coronary Artery Disease363
- Multiple Myeloma327
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction97
- Congenital Heart Disease84
- Peripheral Arterial Disease79
- Stroke, Ischemic78
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital68
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California453
- Alabama196
- Arizona181
- Massachusetts173
- New York168
- Florida140
- Texas122
- Maryland118
- Minnesota117
- Illinois112
Recruiting studies9,609 total
- NCT06277427Recruiting
CAR-T cell therapy for refractory vasculitis and lupus nephritis
This trial tests a new type of cell therapy called CAR-T cells that target BCMA (a protein on certain immune cells) for people with two autoimmune diseases: ANCA-associated vasculitis and lupus nephritis. It is for patients whose disease has not responded to standard treatments or has come back after initial improvement.
Wuhan, HubeiAges 18–70 - NCT04656184RecruitingPhase 3
Anakinra vs IVIG for kids who don’t respond to first IVIG
This study compares two treatments—anakinra and IVIG—for children with Kawasaki disease who still have fever after their first standard IVIG treatment. It aims to find which option works better and is safer for “IVIG non-responders” who may be at risk for heart complications.
Le Kremlin-Bicêtre, Val De MarneAges 3 months–17 years - NCT06055504Recruiting
Personalized defibrillator plan for non-ischemic heart failure (SPANISH-1)
This trial is testing a personalized approach to deciding who gets an implantable defibrillator (ICD) for people with heart failure due to dilated cardiomyopathy (not from blocked arteries). It aims to see if MRI scans and other factors can better match the device to those who need it most.
Santiago de Compostela, A CoruñaAges 18 years+ - NCT05928728RecruitingPhase 3
Colchicine for people with certain irregular heartbeats
This trial tests whether colchicine can help people with paroxysmal or persistent atrial fibrillation (AF), a type of irregular heartbeat, after a successful cardioversion. It may help reduce future AF problems, depending on the results.
HellerupAges 18 years+ - NCT06275009Recruiting
Lifestyle and fitness study for working adults
This study follows working adults over time to learn how lifestyle and physical fitness affect long-term health. If you join, you'll help researchers understand how to prevent heart disease and other conditions.
Beijing, Beijing MunicipalityAges 18–59 - NCT07863115Recruiting
Preventing blood clots after leg injury with a cast
This study looks at a simple checklist to see who is at risk for blood clots after a leg injury that requires a cast or brace. It also checks how well people follow blood-thinning medication to prevent these clots.
MonastirAges 18 years+ - NCT07865936Recruiting
Heart health check for fatty liver disease patients
This study looks at heart health in people with fatty liver disease (MASLD) by measuring calcium in the heart's arteries with a special scan, to see if they are at risk for heart problems.
Bangkok, BangkoknoiAges 35–75 - NCT07857044Recruiting
Left atrial fibrosis in persistent atrial fibrillation study
This study looks at how scar tissue in the heart's upper chambers relates to other health issues in people with persistent atrial fibrillation. It aims to improve understanding and treatment for this condition.
Augsburg, BavariaAges 18 years+ - NCT07868822Recruiting
Wall squats for blood pressure in adults with high blood pressure
This trial tests whether doing wall squats can help lower blood pressure in adults with high blood pressure. It's a simple exercise you can do at home, and it might be an easy way to improve your heart health along with your usual medication.
Seoul, SeoulAges 19 years+ - NCT07859020Recruiting
AI-assisted diagnosis of fast heart rhythms from ECG
This study uses artificial intelligence to analyze ECG recordings and help identify the exact type and location of fast heart rhythms (tachycardia). It may improve the accuracy and speed of diagnosis for conditions like supraventricular tachycardia, Wolff-Parkinson-White syndrome, premature ventricular contractions, and ventricular tachycardia.
Incheon, IncheonAges 19 years+ - NCT06282939Recruiting
Optima Coil Registry for Brain Aneurysm Treatment
This registry tracks how well the Optima Coil System works to treat brain aneurysms. It is for adults with a berry-shaped aneurysm that hasn't been treated before and is smaller than 24 mm. The goal is to see how safe and effective these coils are in real-world use.
Plano, TexasAges 18 years+ - NCT04593498Recruiting
Test for abnormal heart rhythm triggers for some heart rhythm types
This study looks at people who have frequent abnormal signals from the upper heart (supraventricular extra beats or short runs) and how that relates to atrial fibrillation risk. If you qualify, you may help researchers understand better ways to prevent or manage certain heart rhythm problems.
StockholmAges 70–89 - NCT06282796Recruiting
Early heart risk monitoring for breast cancer chemo
This study tests a method to predict and warn about heart damage from a common type of breast cancer chemotherapy. If you have HER2-positive breast cancer and will receive anthracycline drugs, this trial may help monitor your heart health.
Fuzhou, FujianAges 18–80 - NCT06285084Recruiting
Deep learning ECG test for sports eligibility
This trial uses a deep learning computer program to analyze your heart's electrical activity (ECG) during a routine check-up. It aims to help doctors decide if it's safe for you to play competitive sports.
Milan, LombardyAges 18–60 - NCT06288165Recruiting
Sinus reducer trial for persistent chest pain
This study tests a device called the sinus reducer for people with long-lasting chest pain that hasn't improved with medication or other procedures. It may help if you have limited options for treatment.
Lubin, Lower Silesian VoivodeshipAges 18 years+ - NCT05455489Recruiting
MitraClip registry for severe mitral valve leakage patients
This registry study collects information on people with severe mitral valve leakage (regurgitation) who are treated with the MitraClip G4 device. It aims to better understand which patients benefit most and how well the procedure works in real-world care.
San Donato Milanese, MilanoAges 18 years+ - NCT04703699Recruiting
Study of a heart valve implant after 30 days
This study looks at people who already received the Myval THV heart valve implant for severe native aortic valve narrowing. It checks how patients are doing after at least 30 days of follow-up to better understand the valve’s performance.
TallinnAges 18 years+ - NCT05777551Recruiting
High-power short treatment for irregular heartbeat
This trial studies a specific heart-rhythm procedure that uses higher power for a shorter time to treat atrial fibrillation (AF), an irregular heartbeat. It may help some people control AF and reduce rhythm episodes, while doctors compare outcomes using their chosen approach.
ParisAges 18–80 - NCT06288633Recruiting
Heart nerve ablation for slow heart rhythm
This test uses a procedure to ablate (destroy) specific nerves in the heart that may be causing your heart to beat too slowly. The goal is to help your heart speed up naturally when needed, so you may avoid needing a permanent pacemaker.
Saint PetersburgAges 18–65 - NCT05298436Recruiting
South London stroke registry using health data
This study collects information about people who have had a stroke to learn how to improve care and support. It mainly uses existing medical and health records rather than testing a new medicine.
LondonAges 18 years+ - NCT05002543Recruiting
Real-world study of heart valve repair devices for multiple valves
This study checks how well and how safely CORCYM valve devices work in real-world patients with heart valve problems in the aortic, mitral, and/or tricuspid positions. It may help doctors understand expected outcomes outside of tightly controlled research settings.
Indianapolis, IndianaAges Any age - NCT05746923Recruiting
Heart failure hospital registry for adults in Krakow area
This registry collects information from adults who were recently hospitalized for acute heart failure. It helps researchers better understand who is affected and how care is delivered after hospitalization.
KrakowAges 18 years+ - NCT05750147Recruiting
Study for cardiomyopathy linked to family or genes
This study looks at people with cardiomyopathy (or related heart muscle conditions) and those who may be at risk because of family history or genetic test results. It may help researchers better understand who is likely to develop the condition and how best to monitor or support them.
LondonAges Any age - NCT05961488Recruiting
Coronary CT scan after cardiac arrest to check heart artery blockage
This trial tests whether a special CT scan (coronary CT angiography) can help rule out coronary artery disease—the common artery blockage causing heart problems—after someone has survived an out-of-hospital cardiac arrest. It may help doctors quickly decide who needs or does not need further heart procedures.
ReimsAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,609 recruiting cardiology studies from the U.S. registry right now, out of 14,617 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.