Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,049 recruiting studies in this area right now.
By phase
- Not applicable8,023
- Phase 2486
- Phase 4480
- Phase 3451
- Phase 1361
- Phase 1/Phase 2161
- Phase 2/Phase 387
Top conditions
- Stroke854
- Heart Failure568
- Hypertension401
- Cardiovascular Diseases390
- Coronary Artery Disease372
- Multiple Myeloma330
- Atrial Fibrillation272
- Ischemic Stroke199
- Atrial Fibrillation (AF)145
- Acute Ischemic Stroke141
- Pulmonary Hypertension103
- Myocardial Infarction99
- Congenital Heart Disease86
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Massachusetts General Hospital51
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Insel Gruppe AG, University Hospital Bern50
- Johns Hopkins University47
Where studies are running
- California468
- Alabama199
- Massachusetts182
- Arizona176
- New York165
- Florida145
- Maryland120
- Minnesota120
- Illinois119
- Texas119
Recruiting studies10,046 total
- NCT06966258Recruiting
Heart health program for Black women in Birmingham
This trial tests a program called Inspire HER, which aims to improve heart and emotional health for Black women with early-stage cardiovascular-kidney-metabolic syndrome. You may qualify if you have this condition and live in the Birmingham area.
Birmingham, AlabamaAges 30–79 - NCT06966674Recruiting
Tirofiban for no-reflow in heart attack patients
This trial tests if a drug called tirofiban, given directly into the heart artery, can prevent or treat no-reflow (when blood doesn't flow well even after the blockage is opened) in people having a severe heart attack known as STEMI.
Kafr ash Shaykh, KafrelsheikhAges 18 years+ - NCT06967194Recruiting
Early beta blocker use after heart attack with fast heart rate or low blood pressure
This trial is testing whether giving a beta-blocker medication (metoprolol) early after a heart attack can help people who have a fast heart rate or low blood pressure but no signs of organ failure. The goal is to see if this treatment improves recovery.
Tel AvivAges 18 years+ - NCT06968611Recruiting
Diabetes and vision care study in Bangladesh
This study tests a program that combines diabetes care with eye exams for people in Bangladesh who were recently diagnosed with diabetes. The goal is to see if this approach helps you better manage your health and prevent vision problems.
DinajpurAges 30 years+ - NCT06968637Recruiting
Improving diabetes and vision care in Bangladesh
This study tests a new way to combine diabetes care with eye care for people with diabetes in Bangladesh. If you have diabetes and a diabetes-related eye condition, this might help improve your care.
Dinajpur Sadar, DinajpurAges 30 years+ - NCT06968663RecruitingPhase 2
Brain stimulation with speech therapy for recent stroke aphasia
This study tests if adding a non-invasive brain stimulation technique (transcranial magnetic stimulation) to language therapy can improve speech recovery in people who had a stroke 2 to 6 weeks ago and now have aphasia (trouble speaking or understanding language).
Philadelphia, PennsylvaniaAges 18–85 - NCT06968923Recruiting
Home rehab program for stroke survivors with aphasia or memory issues
This trial tests a home-based rehabilitation program using the Euleria Home® device for people who have had a first ischemic stroke and have trouble speaking (aphasia) or thinking (cognitive deficits). The goal is to help you recover from home using a simple device and internet connection.
Verona, veronaAges 18–90 - NCT06969274Recruiting
Nerve Block vs. Spinal Block for Hemorrhoid Surgery
This study compares two ways to numb the area for hemorrhoid surgery: an ultrasound-guided nerve block near the tailbone (sacral erector spinae plane block) versus a traditional spinal 'saddle block.' The goal is to see which provides better pain relief and fewer side effects.
CairoAges 18–65 - NCT06969560Recruiting
Wearable monitor for heart failure in kids
This study tests a wearable patch (like a smart bandage) that tracks your heart health at home. It's for children and teens with heart failure to help doctors monitor them without frequent hospital visits.
Edmonton, AlbertaAges 8–18 - NCT06969729Recruiting
3D-printed aortic stent graft trial for aneurysms
This trial tests a custom-made aortic stent graft created with 3D printing technology for people with certain types of abdominal or thoracoabdominal aortic aneurysms. It aims to see if this new device is safe and works well to repair the aneurysm.
Szczecin, West Pomeranian VoivodeshipAges 18 years+ - NCT06969924Recruiting
How CRT works for adults with congenital heart disease
This study looks at how well cardiac resynchronization therapy (CRT) works for adults who were born with a heart defect. Researchers will review medical records to see if the therapy helps improve heart function.
Leiden, South HollandAges 18 years+ - NCT06971068Recruiting
Vacuum-assisted laser treatment for large leg veins
This study tests a new laser treatment that uses a small vacuum to remove large varicose veins in the legs. It may help people with big, uncomfortable veins that other treatments might not work as well for.
MinskAges 18–90 - NCT06971380RecruitingPhase 2
CAR-T therapy for multiple myeloma and amyloidosis
This trial tests a new CAR-T cell treatment (HBI0101) for people with multiple myeloma or light-chain amyloidosis that has come back or stopped responding to other treatments. The therapy uses your own immune cells to fight cancer, and the goal is to see if it can help control the disease.
JerusalemAges 18 years+ - NCT06971848Recruiting
Skin testing for biologic drug allergies
This trial checks if people can safely receive certain biologic drugs without allergic reactions, using skin tests to see how the body reacts. It may help find out if you are allergic to a biologic medicine you have taken before.
AngersAges 18 years+ - NCT06972225Recruiting
Study of heart outcomes after drug-coated balloon treatment
This study looks at heart-related complications in adults who had a coronary angioplasty using a drug-eluting balloon. It aims to understand how well these balloons work over time.
Québec, QuebecAges 18 years+ - NCT06972355Recruiting
Treadmill walking with hidden vision for stroke rehab
This trial tests if walking on a treadmill with a screen that hides vision can help people recovering from a stroke improve their balance and mobility. It is for people who had a stroke less than 6 months ago and can already walk a little with support.
MetzAges 18 years+ - NCT06973031Recruiting
Testing a new system for treating atrial fibrillation
This trial tests a new device that uses pulsed electric fields to treat atrial fibrillation (AF), a type of irregular heartbeat. It aims to see if this approach is safe and effective for people with AF that comes and goes or lasts for a short time.
KaiserslauternAges 18–80 - NCT06973590Recruiting
Blood flow restriction and nerve stimulation for stroke recovery
This trial tests whether combining blood flow restriction with mild electrical nerve stimulation can improve ankle and leg movement after a stroke. It may help you if you had a single stroke more than 6 months ago and can walk a short distance on your own.
Hong KongAges 50–80 - NCT06973902Recruiting
A study on heart pump therapy and stress echo for advanced heart failure
This trial tests how well a heart stress ultrasound (dobutamine echo) can predict if you will get better from a special heart device called cardiac contractility modulation (CCM). CCM is a pacemaker-like implant for people with advanced heart failure who still have symptoms even with the best medicines. The study will help doctors know which patients benefit the most from this device.
Marcianise, CampaniaAges 18 years+ - NCT06974279Recruiting
TMS for language recovery after stroke
This trial tests a non-invasive brain stimulation technique called TMS to help improve language after a stroke. It is for people who had a left-sided stroke and are at least one month past their stroke.
Milwaukee, WisconsinAges 18 years+ - NCT06974786RecruitingPhase 2
T-cell engager vs stem cell transplant for newly diagnosed myeloma
This trial compares two approaches after initial therapy for newly diagnosed multiple myeloma: a T-cell engager (elranatamab) versus a stem cell transplant. The goal is to see which provides better control of the disease, using sensitive MRD testing to guide further treatment.
Birmingham, AlabamaAges 19 years+ - NCT06975696Recruiting
Fusion imaging for stroke clot removal
This trial tests a new imaging technique to help doctors see blood clots more clearly during a procedure to remove them from the brain. It may help patients having a stroke who are already eligible for clot removal.
HelsinkiAges 18 years+ - NCT06976073Recruiting
Skin imaging study using non-invasive scan
This trial uses a special camera to measure the composition and structure of the skin without any needles or cuts. It helps researchers understand how skin varies between people.
StockholmAges 18 years+ - NCT06976437RecruitingEarly Phase 1
Testing donor CAR-T cells for B-cell blood cancers
This trial tests a new treatment using specially engineered immune cells from a healthy donor to fight certain B-cell blood cancers that have come back or not responded to standard therapy. It aims to see if these cells can safely help patients achieve remission.
Zhenjiang, JiangsuAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,049 recruiting cardiology studies from the U.S. registry right now, out of 15,440 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.