Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,049 recruiting studies in this area right now.
By phase
- Not applicable8,023
- Phase 2486
- Phase 4480
- Phase 3451
- Phase 1361
- Phase 1/Phase 2161
- Phase 2/Phase 387
Top conditions
- Stroke854
- Heart Failure568
- Hypertension401
- Cardiovascular Diseases390
- Coronary Artery Disease372
- Multiple Myeloma330
- Atrial Fibrillation272
- Ischemic Stroke199
- Atrial Fibrillation (AF)145
- Acute Ischemic Stroke141
- Pulmonary Hypertension103
- Myocardial Infarction99
- Congenital Heart Disease86
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Massachusetts General Hospital51
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Insel Gruppe AG, University Hospital Bern50
- Johns Hopkins University47
Where studies are running
- California468
- Alabama199
- Massachusetts182
- Arizona176
- New York165
- Florida145
- Maryland120
- Minnesota120
- Illinois119
- Texas119
Recruiting studies10,046 total
- NCT06976606Recruiting
A study of adults with PKP2-linked arrhythmogenic cardiomyopathy
This study follows people with a confirmed PKP2 genetic mutation and arrhythmogenic cardiomyopathy (ACM) to understand how their condition changes over time. It may help doctors learn more about the disease and plan future treatments.
Redwood City, CaliforniaAges 18–65 - NCT06977230Recruiting
Arm-cuff protection before heart bypass in diabetes
This study tests whether a simple arm-cuff procedure done before heart bypass surgery can help protect the heart in people with type 2 diabetes. The goal is to see if this technique reduces complications during and after the operation.
MuğlaAges 45–85 - NCT06977295Recruiting
Testing a new software for finding coronary artery disease
This study is testing a new computer program that helps doctors see if you have coronary artery disease (blockages in the heart's blood vessels). It looks back at past CT scans of the heart to see if the software works well compared to other tests.
VilleurbanneAges 18 years+ - NCT06978413Recruiting
Telerehab through digital tech for stroke recovery
This trial tests whether telerehabilitation using digital tools can help stroke survivors recover better. It aims to see if remote therapy is effective during the months after a stroke.
AcerenzaAges 18 years+ - NCT06978439RecruitingPhase 4
Blood thinner dosing for children with Kawasaki aneurysm
This study tests the best dose of a blood thinner called rivaroxaban for children with a giant coronary artery aneurysm after Kawasaki disease. The goal is to prevent dangerous blood clots.
Shanghai, Shanghai MunicipalityAges 1 month–18 years - NCT06978647RecruitingPhase 1
YTS109 cell therapy for stubborn autoimmune diseases
This trial tests a new cell therapy called YTS109 for people with certain autoimmune diseases like lupus that have not improved with standard treatments. It aims to see if this therapy can help control disease activity.
Beijing, Beijing MunicipalityAges 18–65 - NCT06978998Recruiting
Retinal photos to help predict heart failure outcomes
This study tests whether a simple eye photo can help doctors better predict the course of heart failure with reduced pumping strength. If it works, this low-cost test could improve care for people with this condition.
SeoulAges 20 years+ - NCT06979284Recruiting
Ultrasound inside artery for severe leg blockages
This trial tests whether using a special ultrasound probe inside the artery (called intravascular ultrasound) helps guide treatment for people with severe leg artery blockages that cause pain, wounds, or gangrene. The goal is to see if it improves blood flow and saves the leg.
HamiltonAges 18 years+ - NCT06979375RecruitingPhase 2
Study of CDR132L for heart failure with reduced pumping ability and thickened heart muscle
This trial tests a new medicine called CDR132L to see if it improves heart structure and function in people with heart failure who have a thickened heart muscle and reduced pumping ability. Participants will be randomly assigned to receive either the study drug or a placebo.
Concord, New South WalesAges 40–84 - NCT06979466Recruiting
Electrical device for chronic stroke recovery
This trial tests a device that uses electrical stimulation to help people who had a stroke several months to years ago improve arm and hand movement. You would use the device while sitting and do physical exercises with help from a caregiver.
White Plains, New YorkAges 18–80 - NCT06979700Recruiting
Early wake-up predictors after cardiac arrest
This study looks at patients who had a cardiac arrest outside the hospital and are still unconscious after their heartbeat returns. The goal is to find early signs that predict when someone will wake up.
Aarhus NAges 18 years+ - NCT06979726RecruitingPhase 4
Lasix under the skin for heart failure symptoms
This study tests a way to give a common water pill (called Lasix, or furosemide) under the skin using a small pump at home, instead of in the hospital. It may help people with heart failure who have fluid buildup that isn't getting better with oral water pills.
Gainesville, FloridaAges 18–80 - NCT06980597RecruitingPhase 1
Testing OL-108 for active autoimmune diseases
This trial tests an investigational drug called OL-108 for people with certain autoimmune diseases (lupus, myositis, scleroderma, or vasculitis) that have come back or not responded to standard treatments. The goal is to see if it's safe and if it can help control the disease.
BeijingAges 18–65 - NCT06980584Recruiting
Treating nonthrombotic pulmonary hypertension from fibrosing mediastinitis
This study tests a treatment for a rare lung condition called fibrosing mediastinitis, where scar tissue in the chest presses on the lung artery, causing high blood pressure in the lungs. The goal is to see if the treatment can improve your symptoms and quality of life.
BeijingAges 18–85 - NCT06981624Recruiting
Comparing routine vs. selective heparin to prevent artery blockage after catheter procedure
This trial tests whether giving a blood-thinner called heparin to all patients during a procedure through the wrist (radial artery) is better than giving it only when needed. The goal is to see which approach reduces the risk of the artery getting blocked afterward.
Québec, QuebecAges 18 years+ - NCT06983613Recruiting
New heart rhythm after PFO closure study
This study looks at whether closing a small hole in the heart (called a PFO) can cause new heart rhythm problems. It is for people who had a stroke caused by a PFO and are planning to have it closed.
PragueAges 18 years+ - NCT06983808Recruiting
Digital rehab before heart surgery
This trial tests a digital program to help you prepare for heart surgery. It uses a smartphone or tablet to guide you through exercises and education before your operation, which may help you recover faster.
Melbourne, VictoriaAges 18–100 - NCT06983821RecruitingPhase 3
Low-dose steroids for kidney disease from vasculitis
This trial tests lower steroid doses for people with certain types of vasculitis that have newly affected their kidneys. The goal is to find out if a lower dose works just as well with fewer side effects.
Hamilton, OntarioAges 18 years+ - NCT06984211Recruiting
Measuring artery stiffness to gauge heart disease risk
This study tests a new handheld device that uses gentle pulses to measure stiffness of your arteries, which can help predict heart disease risk. It is a quick, non-invasive test for people coming in for regular check-ups.
StockholmAges 18 years+ - NCT06984445Recruiting
Cord Blood Protein in Anemia Transfusion Study
This study measures a protein (S100B) in cord blood from babies who had or did not need a blood transfusion in the womb for hemolytic disease. It looks for possible markers of brain health.
WarsawAges 18 years+ - NCT06984731Recruiting
Same-day ablation and WATCHMAN closure for AFib
This study tests whether doing a common AFib procedure (radiofrequency ablation) is safe and effective at the same time as closing off the left atrial appendage with the WATCHMAN FLX device. It's for people with nonvalvular atrial fibrillation who are already candidates for both treatments.
Nantong, JiangsuAges 18–80 - NCT06984965Recruiting
Using EEG to Distinguish Types of Stroke
This study uses an EEG (a cap that records brain waves) to help tell the difference between two types of stroke: ischemic (caused by a clot) and hemorrhagic (caused by bleeding). It may help doctors choose the right treatment faster for patients who have a stroke.
Asyut, Asyut GovernorateAges 18–80 - NCT06985901Recruiting
Pulsed-field ablation for persistent atrial fibrillation
This trial tests a new type of ablation (pulsed-field) to treat persistent atrial fibrillation (AFib) that lasts more than 7 days. You may qualify if you have symptoms and haven't had other heart ablation procedures except for one specific type.
NiceAges 18 years+ - NCT06986174RecruitingPhase 2
Pacritinib for relapsed or refractory Waldenström macroglobulinemia
This trial tests a pill called pacritinib for people with Waldenström macroglobulinemia that has come back or stopped responding to other treatments. The goal is to see if pacritinib can help control the disease by blocking certain proteins that cancer cells need to grow.
Boston, MassachusettsAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,049 recruiting cardiology studies from the U.S. registry right now, out of 15,440 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
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- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.