Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,049 recruiting studies in this area right now.
By phase
- Not applicable8,023
- Phase 2486
- Phase 4480
- Phase 3451
- Phase 1361
- Phase 1/Phase 2161
- Phase 2/Phase 387
Top conditions
- Stroke854
- Heart Failure568
- Hypertension401
- Cardiovascular Diseases390
- Coronary Artery Disease372
- Multiple Myeloma330
- Atrial Fibrillation272
- Ischemic Stroke199
- Atrial Fibrillation (AF)145
- Acute Ischemic Stroke141
- Pulmonary Hypertension103
- Myocardial Infarction99
- Congenital Heart Disease86
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Massachusetts General Hospital51
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Insel Gruppe AG, University Hospital Bern50
- Johns Hopkins University47
Where studies are running
- California468
- Alabama199
- Massachusetts182
- Arizona176
- New York165
- Florida145
- Maryland120
- Minnesota120
- Illinois119
- Texas119
Recruiting studies10,046 total
- NCT07086534Recruiting
GeminiOne Clip for Severe Mitral Regurgitation
This trial tests a new device called GeminiOne that clips together part of your leaky mitral valve to reduce backward blood flow. It is for people with severe mitral regurgitation who are not candidates for open-heart surgery.
Thousand Oaks, CaliforniaAges 18 years+ - NCT07087184Recruiting
Milk intake and heart health study
This study looks at how drinking dairy milk affects cholesterol levels. You use a smartphone app to track your milk intake and give blood samples.
San Francisco, CaliforniaAges 18 years+ - NCT07086989Recruiting
Heart health study for kids with chronic conditions
This study looks at heart disease risk in children and young adults (ages 6-25) with long-term health conditions like certain heart, kidney, or diabetes disorders. The goal is to better understand and manage heart risks early.
BudapestAges 6–25 - NCT07087431Recruiting
Genetic risk score for heart disease and health habits
This study looks at whether sharing a genetic risk score for heart disease can help people make heart-healthy changes. If you're not on cholesterol medication, you may be able to join.
Boston, MassachusettsAges 30–75 - NCT07087587Recruiting
Sleep apnea treatment for AFib: a personalized trial
This study tests whether treating sleep apnea with a CPAP machine can reduce the number of AFib episodes you have. It's a personalized 'N-of-1' trial, meaning you'll try both CPAP and no CPAP at different times to see what works best for you.
Cleveland, OhioAges 18–85 - NCT07087613Recruiting
Detecting heart and lung pressure problems with a smart stethoscope
This study tests if a digital stethoscope and a simple 3-lead ECG (heart rhythm test) can detect two heart conditions: high blood pressure in the lungs (pulmonary hypertension) and low pumping strength of the heart (low ejection fraction). It's intended for adults who recently had a heart ultrasound or a heart catheterization.
O'Fallon, IllinoisAges 18 years+ - NCT07087743Recruiting
Virtual reality rehab for walking after stroke
This study uses virtual reality to help people who have had a stroke improve their walking. It provides feedback on how you push off with your feet, which may strengthen your walking pattern.
Galveston, TexasAges 20 years+ - NCT07087782Recruiting
Early high-calorie formula for infants with single ventricle heart condition
This trial tests whether starting a special high-calorie formula (Fortini) early helps infants with a single ventricle heart condition grow better and have fewer health problems between surgeries. It might improve outcomes before their next surgery.
Corpus Christi, TexasAges birth–6 months - NCT07087769Recruiting
Improving walking symmetry after stroke with special devices
This study uses special devices and feedback to help people who have had a stroke walk more evenly (symmetrically). It tests if these tools can improve walking patterns and balance.
Galveston, TexasAges 20 years+ - NCT07087912RecruitingPhase 4
Dengue vaccine safety in people with autoimmune rheumatic diseases
This study tests the safety and immune response of a dengue vaccine in people aged 12–59 with stable autoimmune rheumatic diseases (like rheumatoid arthritis or lupus) who are on low-dose or no immune-suppressing medications. It also includes healthy volunteers for comparison.
São Paulo, São PauloAges 12–59 - NCT07088107Recruiting
Brain training with TMS and fNIRS for arm recovery after stroke
This trial uses a brain-computer interface (TMS and fNIRS) to help people with chronic stroke regain arm function. It tests if combining brain stimulation with real-time brain activity feedback can improve movement.
Hong KongAges 18–80 - NCT07088250Recruiting
Statins for Treating Brain Bleeding
This trial tests if the statin drug atorvastatin can help people recover from a type of stroke called a brain bleed. It is for adults who have a moderate-sized bleed in the upper part of the brain and can start taking the drug within 48 hours of symptoms.
Anqing, AnhuiAges 18–80 - NCT07089095Recruiting
Choosing rehab after a stroke: your preferences matter
This study looks at what matters to you when choosing rehabilitation care after a recent stroke. By joining, you can help doctors understand how to better support people like you in recovery.
TaipeiAges 18 years+ - NCT07089602RecruitingPhase 4
Placental membrane for diabetic and venous leg ulcers
This trial tests if a placental membrane product, when added to standard wound care, helps heal diabetic foot ulcers and venous leg ulcers faster than standard care alone.
Philidelphia, PennsylvaniaAges 18 years+ - NCT07090057Recruiting
Targeting the plantaris muscle in ankle surgery for children
This study tests if removing the plantaris muscle during surgery improves ankle movement in children with tight heel cords. It aims to see if this extra step leads to better outcomes.
Edmonton, AlbertaAges 4–17 - NCT07090161RecruitingPhase 2
Study of iloperidone for uncontrolled high blood pressure
This trial tests if iloperidone can lower blood pressure in people whose high blood pressure is not controlled by current medications. You may qualify if your blood pressure is still high after weeks of treatment.
Phoenix, ArizonaAges 18–65 - NCT07090200Recruiting
Rehabilitation program for COPD with heart or blood vessel disease
This study tests a rehabilitation program for people with COPD who also have heart or blood vessel problems. It aims to help you breathe better and improve your overall health.
Wuhan, HubeiAges 18 years+ - NCT07091045Recruiting
Robot-Assisted Foot-Ankle Training for Stroke Recovery
This trial tests a robot-assisted training program for the foot and ankle in people who have had a stroke at least 6 months ago. The goal is to improve movement and walking by using special exercises guided by a robotic device.
Istanbul, IstanbulAges 40–65 - NCT07091162Recruiting
Genetic and CT screening for heart risk in diabetes
This trial uses your genetic risk score and a CT scan of your heart to see if changing how doctors manage your diabetes can lower your risk of heart problems. It is for adults with type 2 diabetes who haven't had heart disease symptoms.
Melbourne, VictoriaAges 40 years+ - NCT07091851Recruiting
Blood pressure support group for stroke survivors
This study tests whether a group-based program can help people with high blood pressure and a recent mild to moderate stroke better manage their blood pressure. You'll work with a team and use online tools to keep your blood pressure in a healthy range.
Boston, MassachusettsAges 35 years+ - NCT07092644Recruiting
Preeclampsia and baby heart defects: mother's heart study
This study looks at the link between preeclampsia (a pregnancy complication with high blood pressure) and a mother's heart health when her baby has a heart problem. The goal is to understand how the mother's heart adapts during pregnancy in these cases.
RomaAges 18 years+ - NCT07092709RecruitingPhase 3
Tenecteplase for stroke patients who recently took blood thinners
This trial tests if the clot-busting drug tenecteplase is safe and effective for people having an ischemic stroke who have recently taken blood thinners (DOACs). If you qualify, you may receive either tenecteplase or a placebo within 24 hours of your last known well time.
Guangzhou, GuangdongAges 18 years+ - NCT07093554RecruitingPhase 1
Talquetamab and Cilta-cel for relapsed multiple myeloma
This trial tests giving an immunotherapy drug (talquetamab) before CAR T-cell therapy (cilta-cel) to see if it helps people with multiple myeloma that has come back or stopped responding to other treatments.
Milwaukee, WisconsinAges 18 years+ - NCT07094425Recruiting
Heart function study for ICU patients on breathing machines
This study looks at how the heart is affected in critically ill patients who need a breathing machine. It uses ultrasound and other simple tests to check for heart problems that can happen in the ICU, which may help doctors find and treat them earlier.
Vienna, State of ViennaAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,049 recruiting cardiology studies from the U.S. registry right now, out of 15,440 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Pain
- Injuries & trauma
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.