Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,049 recruiting studies in this area right now.
By phase
- Not applicable8,023
- Phase 2486
- Phase 4480
- Phase 3451
- Phase 1361
- Phase 1/Phase 2161
- Phase 2/Phase 387
Top conditions
- Stroke854
- Heart Failure568
- Hypertension401
- Cardiovascular Diseases390
- Coronary Artery Disease372
- Multiple Myeloma330
- Atrial Fibrillation272
- Ischemic Stroke199
- Atrial Fibrillation (AF)145
- Acute Ischemic Stroke141
- Pulmonary Hypertension103
- Myocardial Infarction99
- Congenital Heart Disease86
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Massachusetts General Hospital51
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Insel Gruppe AG, University Hospital Bern50
- Johns Hopkins University47
Where studies are running
- California468
- Alabama199
- Massachusetts182
- Arizona176
- New York165
- Florida145
- Maryland120
- Minnesota120
- Illinois119
- Texas119
Recruiting studies10,046 total
- NCT07094919Recruiting
Corheart 6 heart pump long-term study
This study follows people who have already received the Corheart 6 heart pump to see how well it works over time. You may qualify if you have severe heart failure that doesn't improve with standard treatments and you got the pump after October 1, 2021.
Shenzhen, GuangdongAges 18 years+ - NCT07094737Recruiting
Heart rehab study for coronary disease or heart failure
This study tracks how well heart rehabilitation works for people with coronary artery disease or heart failure. It aims to improve future care by learning from your experience.
MilanAges 18 years+ - NCT07094763Recruiting
Tenecteplase for posterior stroke 4.5-24 hours after onset
This trial tests a clot-busting drug called tenecteplase for people who had a stroke affecting the back part of the brain (posterior circulation). It may be an option if you can get treatment between 4.5 and 24 hours after symptoms started.
HefeiAges 18–100 - NCT07095452RecruitingPhase 2/Phase 3
Newly diagnosed myeloma: comparing drug combinations for non-transplant patients
This trial tests a new combination of two drugs (etentamig and daratumumab) against the current standard of daratumumab plus lenalidomide and dexamethasone in people recently diagnosed with multiple myeloma who cannot have a stem cell transplant. The goal is to see which combination better controls the disease while keeping side effects manageable.
Scottsdale, ArizonaAges 18 years+ - NCT07095660Recruiting
Catheter device for leg vein blockages
This trial tests a new catheter device to remove blockages in the large veins of your legs. It may help if you have chronic leg swelling or pain from vein problems.
GalwayAges 18 years+ - NCT07095829Recruiting
Predicting circulation after birth for severe pulmonary valve blockage
This study looks at babies with a severe heart defect where the pulmonary valve is blocked and the wall between the heart's lower chambers is intact. It aims to predict how well blood will flow after birth using ultrasound images taken during pregnancy.
MadridAges 4 months–6 months - NCT07095959Recruiting
Ethanol vein infusion plus pulsed field ablation for paroxysmal AF
This study compares two treatments for paroxysmal atrial fibrillation (AF that comes and goes): using pulsed electric field ablation alone versus combining it with ethanol infusion into a specific vein. The goal is to see which approach works better for first-time ablation patients.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07096544Recruiting
Using a lung artery sensor to guide LVAD care
This study tests whether a small sensor (CardioMEMS) implanted in the lung artery can help doctors better manage LVAD settings and reduce hospital visits. It is for people who already have a HeartMate 3 heart pump and are stable enough to go home.
Plano, TexasAges 21–85 - NCT07096687Recruiting
Cooling treatment for acute ischemic stroke
This trial tests whether lowering body temperature (targeted temperature management) can help people who have had a stroke within the last 48 hours. It focuses on strokes caused by a blockage in a specific part of the brain's blood supply, and aims to see if cooling can reduce brain damage.
Bologna, BolognaAges 18 years+ - NCT07096973Recruiting
Heart rehab recovery study in Davos
This study looks at how people recover during heart rehabilitation at a clinic in Davos. By tracking your progress, researchers hope to learn what helps people get better.
Davos, Kanton GraubündenAges 18 years+ - NCT07097740Recruiting
Study of a new polymer heart valve for mitral or aortic replacement
This study tests a new type of prosthetic heart valve made from a special polymer material. It is for adults who need surgical replacement of either the mitral or aortic valve.
Shanghai, Shanghai MunicipalityAges 50 years+ - NCT07098065Recruiting
Health warnings and counseling to help you quit smoking
This trial tests whether health warnings and counseling can help smokers quit. You'll get support during visits to your local pharmacy.
DhakaAges 18–90 - NCT07099144Recruiting
Inhaled nitric oxide for newborns with breathing failure and high blood pressure in the lungs
This trial tests whether inhaled nitric oxide gas can help full-term newborns who have severe breathing problems and high blood pressure in their lungs. It aims to improve oxygen levels and reduce the need for more intensive support.
Guangzhou, GuangdongAges Up to 1 week - NCT07099885Recruiting
Urine test to guide water pill treatment for heart failure
This study tests a simple urine test to help doctors choose the best dose of water pills (diuretics) for people hospitalized with heart failure and leg swelling. The goal is to relieve congestion faster and more safely.
Wroclaw, DolnosląskieAges 18 years+ - NCT07099391RecruitingPhase 1/Phase 2
Study of two drug combos for newly diagnosed multiple myeloma
This trial tests two combinations of drugs (Dara-RVd and Teclistamab-RVd) for people newly diagnosed with multiple myeloma who are eligible for a stem cell transplant. The goal is to see if adding a newer drug called Teclistamab improves outcomes.
Basking Ridge, New JerseyAges 18 years+ - NCT07099417Recruiting
Screening for heart valve disease with a single-lead ECG
This study tests whether a simple single-lead heart monitor (ECG) can spot problems with your heart valves. It may be a quick, easy way to screen for valve disease.
MoscowAges 18 years+ - NCT07099599Recruiting
Image test for blood flow after stroke treatment
This trial uses a special imaging technique to check if blood flow has fully returned to the brain after a stroke clot is removed. It aims to improve understanding of how well the brain's tiny blood vessels are working after treatment.
Cincinnati, OhioAges 18 years+ - NCT07099677Recruiting
How blood pressure drugs affect balance and fall risk
This study looks at how common blood pressure medications might affect your balance and risk of falling in the first few weeks of treatment. It will help doctors understand if certain drugs are safer for balance.
BoluAges 18–75 - NCT07099859RecruitingPhase 4
Losartan after aortic valve surgery for severe leakage
This trial tests if the drug losartan can help the heart recover better after surgery to replace a leaky aortic valve. It may reduce strain on the heart and improve long-term outcomes.
São Paulo, São PauloAges 18–85 - NCT07100067Recruiting
LCAR-F33S for Relapsed/Refractory Multiple Myeloma
This trial tests a new CAR-T cell therapy called LCAR-F33S for people with multiple myeloma that has returned or stopped responding to standard treatments. It aims to see if targeting a specific protein on myeloma cells can help control the disease.
BeijingAges 18 years+ - NCT07101445RecruitingPhase 4
Comparing steroids to prevent reactions to motixafortide in multiple myeloma
This trial tests two different steroid medicines (methylprednisolone and dexamethasone) to see which works better at preventing side effects from motixafortide, a drug used to help collect stem cells for a stem cell transplant in people with multiple myeloma.
Atlanta, GeorgiaAges 18 years+ - NCT07102160Recruiting
Long-term safety and effectiveness of the Cleaner Vac system for blood clots
This study tracks how well the Cleaner Vac® system works to remove blood clots from leg veins over time. It may be an option for people with new or recent deep vein thrombosis (DVT) who are getting their first treatment.
Fort Lauderdale, FloridaAges 18 years+ - NCT07102823Recruiting
A registry study of lung blood vessel health in COPD
This study aims to better understand how COPD affects the blood vessels in your lungs by looking at measurements from a right heart catheterization. It may help doctors identify a specific pattern of lung and heart problems in people with COPD.
GrazAges 18 years+ - NCT07102927Recruiting
Virtual reality training for stroke patients with neglect
This trial tests whether virtual reality exercises can help people with right-brain stroke overcome 'neglect' (trouble noticing things on their left side). It aims to improve daily function and quality of life.
SeoulAges 19–99
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,049 recruiting cardiology studies from the U.S. registry right now, out of 15,440 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.