Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,073 recruiting studies in this area right now.
By phase
- Not applicable8,041
- Phase 2490
- Phase 4483
- Phase 3452
- Phase 1359
- Phase 1/Phase 2162
- Phase 2/Phase 386
Top conditions
- Stroke855
- Heart Failure565
- Hypertension403
- Cardiovascular Diseases389
- Coronary Artery Disease375
- Multiple Myeloma330
- Atrial Fibrillation273
- Ischemic Stroke200
- Atrial Fibrillation (AF)146
- Acute Ischemic Stroke141
- Pulmonary Hypertension104
- Myocardial Infarction98
- Congenital Heart Disease87
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis78
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital54
- Massachusetts General Hospital51
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Insel Gruppe AG, University Hospital Bern50
- Johns Hopkins University47
Where studies are running
- California467
- Alabama198
- Massachusetts181
- Arizona176
- New York166
- Florida146
- Maryland120
- Texas120
- Illinois119
- Minnesota119
Recruiting studies10,070 total
- NCT07083713Enrolling by invitation
Group coaching for life goals with chronic conditions
This study tests if group coaching helps people with certain chronic conditions set and achieve life goals. You would join phone or video sessions with a coach and others like you.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07083115Enrolling by invitation
Using MRI to study atrial fibrillation
This trial uses advanced MRI scans to better understand atrial fibrillation (AFib). If you have been diagnosed with AFib and can safely undergo an MRI, you may be able to join this study at the Cleveland Clinic.
Cleveland, OhioAges 18 years+ - NCT07077811Enrolling by invitation
Pulsed field ablation for heart failure with preserved pumping strength
This trial tests a new procedure called pulsed field ablation for people who have both persistent atrial fibrillation and a type of heart failure (HFpEF). It aims to see if this ablation safely helps control the heart rhythm.
Nantong, JiangsuAges 18–80 - NCT07064525Enrolling by invitationPhase 2
Testing a new drug for high blood pressure
This trial tests a new medicine called SPC1001 Low to see if it can safely lower blood pressure in people with essential hypertension (high blood pressure with no known cause). If you are between 19 and 75 years old and have mild to moderate high blood pressure, this study might be an option.
SeoulAges 19–75 - NCT07063381Enrolling by invitation
Low-frequency stimulation for cognition in atrial fibrillation
This study tests whether low-frequency electrical stimulation can help improve thinking and memory in people with permanent atrial fibrillation and cognitive impairment. Participants will receive the stimulation and have their cognitive function checked over six months.
MoscowAges 60–90 - NCT07058922Enrolling by invitationEarly Phase 1
Beetroot powder for resistant hypertension
This study tests if a powdered beetroot supplement can improve blood flow in the small blood vessels of people with resistant hypertension. If you have hard-to-treat high blood pressure, this might be an option for you.
Rio de Janeiro, Rio de JaneiroAges 18 years+ - NCT07050706Enrolling by invitation
Heart failure and protein levels in the blood
This trial checks if a protein called PRMT5 in the blood is linked to heart function in people with heart failure. It compares healthy volunteers and those with heart failure to see if this protein can help understand the condition better.
Shenzhen, GuangdongAges 18 years+ - NCT07050160Enrolling by invitation
Long-term follow-up after gene therapy for arrhythmogenic cardiomyopathy
This study follows participants who have already received the gene therapy LX2020 for a genetic heart condition called arrhythmogenic cardiomyopathy. It tracks their long-term safety and health outcomes, with no new treatment given.
Ann Arbor, MichiganAges 18–67 - NCT07045987Enrolling by invitation
Early warning for futile clot removal in stroke
This study looks at how to predict when a clot removal procedure (thrombectomy) might not work well for acute ischemic stroke. The goal is to build an early warning system so doctors can better decide on treatment.
Xi’an, ShanxiAges 18 years+ - NCT07045233Enrolling by invitation
Using a brain protection device during TAVR to prevent stroke
This study tests if a special device placed during transcatheter aortic valve replacement (TAVR) can help prevent stroke. It is for adults with severe aortic stenosis who are already scheduled for TAVR.
BeijingAges 18 years+ - NCT07041372Enrolling by invitation
Brain PET Study for Recent Stroke Patients
This study uses a special brain scan (PET) to learn more about how artery hardening (atherosclerosis) affects stroke. It is for people who have just had a stroke and may help doctors understand the disease better.
Seoul, Jong-ro GuAges 19 years+ - NCT07034898Enrolling by invitationPhase 4
Dexmedetomidine vs Labetalol for Airway Stress in Brain Surgery
This trial compares two medicines (dexmedetomidine and labetalol) to see which one better controls stress on the airway during brain surgery in people with high blood pressure. The goal is to find a safer way to manage your heart rate and blood pressure while you are under anesthesia.
CairoAges 30–60 - NCT07034170Enrolling by invitation
Muscle mass and recovery after cardiac arrest
This study looks at how muscle mass affects recovery after a cardiac arrest (when the heart stops). It is for people who stay on a breathing machine in the ICU for more than three days. Researchers will measure muscle to see if it helps predict recovery.
TaipeiAges 18–99 - NCT07033676Enrolling by invitation
Study of a blood marker for heart damage from high blood pressure
This trial looks at a substance in your blood called miR-455-5p to see if it can help doctors understand heart changes caused by high blood pressure. It involves people who have had high blood pressure for over a year and may have some heart symptoms.
Shenzhen, GuangdongAges 18 years+ - NCT07026370Enrolling by invitation
Chinese Health Study: Long-term health follow-up
This study is following up with people who already took part in a large health survey in China. It looks at how multiple health conditions develop over time and why some people stay healthier than others.
Beijing, Beijing MunicipalityAges 20 years+ - NCT07023965Enrolling by invitation
Long-term follow-up study for gene therapy in critical limb ischemia
This study follows up with people who previously took part in a clinical trial testing an experimental gene therapy for critical limb ischemia (severe leg pain or sores due to blocked arteries). It aims to see how well the treatment works over time. If you were in that earlier trial and received at least one dose, joining this follow-up could help researchers learn more about the therapy's lasting effects.
Beijing, Beijing MunicipalityAges 20–85 - NCT07018102Enrolling by invitation
Nurse-led trunk control program for stroke recovery
This study tests a nurse-led program to help stroke patients improve their trunk control while in the hospital. It is designed for patients who have trouble with trunk movement and need extra support during recovery.
TaichungAges 20–80 - NCT07017075Enrolling by invitation
Adjusting CPR hand position using ultrasound
This trial tests if using an ultrasound to guide hand placement during CPR improves outcomes for adults who have a cardiac arrest outside the hospital. It may help decide where to push for more effective chest compressions.
ChanghuaAges 18 years+ - NCT07012096Enrolling by invitation
Preventing high blood pressure with counseling
This study tests whether counseling can help prevent high blood pressure in people who live in slums and are currently healthy. If you join, you may learn ways to keep your blood pressure normal.
DhakaAges 18–70 - NCT07002775Enrolling by invitation
Best CPR position for out-of-hospital cardiac arrest
This trial compares different CPR positions to see which works best for people whose hearts stop outside a hospital. It aims to improve survival by finding the most effective technique.
ChanghuaAges 18 years+ - NCT06999369Enrolling by invitation
Heart failure nutrition app study
This study tests a digital nutrition tool to help people with heart failure improve their health. It is for patients recently hospitalized or seeing their doctor regularly.
Walnut Creek, CaliforniaAges 18–89 - NCT06992284Enrolling by invitation
Heart disease study in Niigata
This study looks at the long-term outlook for people with heart disease in Niigata, Japan. It helps doctors learn more about what affects recovery and health over time.
Niigata, NiigataAges 18 years+ - NCT06988202Enrolling by invitation
Comparing repeat ablation methods for atrial fibrillation
This trial compares different techniques for a second heart ablation procedure in people with atrial fibrillation (AFib) who have already had one ablation. It aims to find the best approach to stop AFib from coming back.
Rochester, New YorkAges 18 years+ - NCT06985654Enrolling by invitationPhase 4
IV fluids before cystoscopy to prevent low blood pressure
This trial tests whether giving fluids through an IV before surgery can prevent blood pressure drops during anesthesia for cystoscopy. It may help patients have a safer and more stable procedure.
Columbia, MissouriAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,073 recruiting cardiology studies from the U.S. registry right now, out of 15,588 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.