Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,073 recruiting studies in this area right now.
By phase
- Not applicable8,041
- Phase 2490
- Phase 4483
- Phase 3452
- Phase 1359
- Phase 1/Phase 2162
- Phase 2/Phase 386
Top conditions
- Stroke855
- Heart Failure565
- Hypertension403
- Cardiovascular Diseases389
- Coronary Artery Disease375
- Multiple Myeloma330
- Atrial Fibrillation273
- Ischemic Stroke200
- Atrial Fibrillation (AF)146
- Acute Ischemic Stroke141
- Pulmonary Hypertension104
- Myocardial Infarction98
- Congenital Heart Disease87
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis78
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital54
- Massachusetts General Hospital51
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Insel Gruppe AG, University Hospital Bern50
- Johns Hopkins University47
Where studies are running
- California467
- Alabama198
- Massachusetts181
- Arizona176
- New York166
- Florida146
- Maryland120
- Texas120
- Illinois119
- Minnesota119
Recruiting studies10,070 total
- NCT05725187Enrolling by invitation
AI tool to predict episodes of atrial fibrillation
This study checks whether an AI prediction tool can spot people at risk for recurring episodes of atrial fibrillation (an irregular heartbeat that comes and goes). It may help doctors identify who is more likely to have paroxysmal episodes and plan care earlier.
GwangjuAges 20 years+ - NCT05722145Enrolling by invitation
Study to assess heart artery blockage risk from CT scans
This study looks at how likely people are to have coronary artery disease (heart artery blockage) based on results from CT scans. It may help doctors better estimate risk and decide what follow-up care you may need.
Singapore, SingaporeAges 21–99 - NCT05714293Enrolling by invitation
CT measurements after surgical aortic valve replacement
This study uses a CT scan (with contrast dye) to measure the coronary artery openings after people have a new aortic valve placed surgically. It aims to see how to best plan or understand coronary blood flow after the surgery.
RomaAges 18–80 - NCT05713357Enrolling by invitation
Mapping the heart’s electrical signals after VT ablation
This study checks whether repeating detailed “electrical mapping” inside the heart can better assess how well catheter ablation is working for an abnormal heart rhythm called ventricular tachycardia. It may help doctors fine-tune treatment plans after your procedure, based on how your heart’s signals change over time.
LjubljanaAges 18–85 - NCT05705297Enrolling by invitation
Ultrasound-guided heart procedure to treat a fast rhythm
This trial tests a way to stop a specific fast heart rhythm (AVNRT) using a freezing treatment guided by an ultrasound camera inside the heart. It may help people whose heart rhythm episodes come from a “slow pathway” wiring circuit.
LjubljanaAges 4–80 - NCT05704309Enrolling by invitation
Study of diabetes prevention participants using brain scans
This study looks at how people who previously took part in a diabetes prevention program are doing over time, including brain health using MRI scans for some participants. It may help researchers understand who is at higher risk for memory and thinking problems and why.
Phoenix, ArizonaAges Any age - NCT05688579Enrolling by invitationPhase 4
Testing an aldosterone-blocking medicine in hard-to-control hypertension
This trial studies whether a medicine that blocks aldosterone (called an MRA) can improve cardiovascular outcomes in people with high aldosterone levels and high blood pressure. You may be asked to take the study medicine and have blood pressure, heart, and lab tests monitored over time.
Ürümqi, XinjiangAges 30–75 - NCT05677568Enrolling by invitation
Registry study for Carillon device in leaky mitral valve
This registry collects health information from adults who already have the Carillon device to treat a leaky mitral valve caused by dilated heart muscle. The goal is to better understand how the device performs in real-world care over time.
AachenAges 18 years+ - NCT05677386Enrolling by invitation
CT heart scan trial to prevent first heart problems
This trial uses a special CT scan of the heart’s arteries to better predict who is at risk of future heart problems. It may help your care team decide how best to lower risk early.
CopenhagenAges 40 years+ - NCT05656768Enrolling by invitation
Study how sleep affects nighttime blood pressure
This study looks at how sleep timing and sleep patterns may change your blood pressure at night. If you are already enrolled in the parent research study, you may be invited to take part here.
Birmingham, AlabamaAges 18 years+ - NCT05628779Enrolling by invitation
Clip procedure to repair a leaking tricuspid valve
This trial studies a minimally invasive “edge-to-edge” clip procedure to reduce severe leakage of the tricuspid valve. It’s for people who still feel unwell despite standard treatments and may be too high-risk for open-heart surgery.
AmsterdamAges 18 years+ - NCT05610423Enrolling by invitation
Study of heart inflammation after COVID-19 vaccination in Norway
This study looks at people who may have developed myocarditis or pericarditis (inflammation of the heart muscle or the lining around the heart) shortly after a COVID-19 vaccine. It compares their health records to vaccination records to understand who is affected and when, which may help improve future care.
OsloAges 5 years+ - NCT05598775Enrolling by invitation
Long-term safety follow-up for CTX0E03 after PISCES III
This study checks how safe CTX0E03 is over the long term in people who already received it in a previous PISCES III trial. It may help confirm long-term safety information for future patients, and you may contribute valuable follow-up data.
Morgantown, West VirginiaAges 35–75 - NCT05544721Enrolling by invitationPhase 4
Nerve-block pain study for thoracic outlet surgery
This trial tests whether a targeted numbing injection near the back helps reduce pain or improve comfort for people having first rib removal surgery for thoracic outlet syndrome. It’s a Phase 4 study, meaning it builds on earlier use of this pain-control approach to see how well it works in routine care.
Jacksonville, FloridaAges 18 years+ - NCT05472597Enrolling by invitation
Follow-up study about heart health after pregnancy
This study is continuing follow-up interviews and surveys to learn about heart health after pregnancy. If you already took part before, it may help researchers understand how postpartum health changes over time.
Orange, CaliforniaAges 18 years+ - NCT05453240Enrolling by invitation
Check long-term safety of an LVIS brain stent
This study looks at how safe and effective the LVIS device is over the long term. It mainly includes adults who had an LVIS stent placed for certain types of brain aneurysms within the past 5 years, using the approved indications.
Aliso Viejo, CaliforniaAges 18 years+ - NCT05450237Enrolling by invitation
Testing thinking and memory questionnaires in people with brain injury
This study checks how well certain questionnaire and testing tools work for people who have brain damage from neurologic conditions and ongoing brain inflammation. It may help future patients by improving which tests are most accurate and easy to use.
Pozzilli, IserniaAges 18–80 - NCT05443321Enrolling by invitation
Health information sharing during hospital transfers
This trial studies whether sharing patients’ health information between hospitals during transfers can improve outcomes. You may be included if you are moved from a specific partner hospital to Brigham and Women’s Hospital and admitted to certain hospital units.
Boston, MassachusettsAges 18 years+ - NCT05441696Enrolling by invitation
Check a noninvasive heart failure blood-flow measurement in hospital
This study tests a device that measures blood flow and pressure in a noninvasive way (using sensors on the body) for people admitted with worsening heart failure. It may help doctors monitor heart failure and potentially lower the chance of coming back to the hospital.
Palo Alto, CaliforniaAges 18 years+ - NCT05407415Enrolling by invitation
Using a phone ECG monitor to improve care for atrial fibrillation
This trial studies whether sending heart rhythm recordings from a phone (using the KardiaMobile ECG device) can improve health care use and patient experience for people with atrial fibrillation. It may help your care team monitor you more smoothly—if you meet the study requirements.
Chicago, IllinoisAges 18–90 - NCT05388019Enrolling by invitation
VAD clinic visit study for new and returning patients
This trial looks at how well a specialized, multidisciplinary clinic works for people who have a ventricular assist device (VAD) and compares new VAD patients with those who have already had standard follow-up visits. It may help improve how care and check-ins are organized after your VAD is implanted.
Boston, MassachusettsAges 18 years+ - NCT05374291Enrolling by invitationPhase 3
Dapagliflozin trial for kidney and heart outcomes in severe CKD
This study tests whether dapagliflozin can improve kidney and heart-related outcomes in people with severe chronic kidney disease (CKD). You would take the study medicine (or a comparison treatment) and be followed to see how your kidneys and heart do over time.
Canberra, Australian Capital TeritoryAges 18 years+ - NCT05371470Enrolling by invitation
Smartphone voice analysis to track depression and anxiety in rehab
This study tests whether a smartphone app that listens to your voice can detect changes in depression and anxiety while you’re in cardiac rehabilitation. If it works, it may help people get timely support during recovery.
Rochester, MinnesotaAges 18 years+ - NCT05368038Enrolling by invitation
Newborn screening program for babies up to 4 weeks old
This trial tests a flexible newborn screening process that looks for certain conditions early in life. It may help by catching problems sooner, when treatment can be started earlier.
Brooklyn, New YorkAges Up to 4 weeks
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,073 recruiting cardiology studies from the U.S. registry right now, out of 15,588 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.