Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,073 recruiting studies in this area right now.
By phase
- Not applicable8,041
- Phase 2490
- Phase 4483
- Phase 3452
- Phase 1359
- Phase 1/Phase 2162
- Phase 2/Phase 386
Top conditions
- Stroke855
- Heart Failure565
- Hypertension403
- Cardiovascular Diseases389
- Coronary Artery Disease375
- Multiple Myeloma330
- Atrial Fibrillation273
- Ischemic Stroke200
- Atrial Fibrillation (AF)146
- Acute Ischemic Stroke141
- Pulmonary Hypertension104
- Myocardial Infarction98
- Congenital Heart Disease87
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis78
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital54
- Massachusetts General Hospital51
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Insel Gruppe AG, University Hospital Bern50
- Johns Hopkins University47
Where studies are running
- California467
- Alabama198
- Massachusetts181
- Arizona176
- New York166
- Florida146
- Maryland120
- Texas120
- Illinois119
- Minnesota119
Recruiting studies10,070 total
- NCT05341986Enrolling by invitation
ED tool to help prevent stroke in atrial fibrillation
This study tests an electronic decision-support tool used in the emergency department (ED) to help clinicians choose the safest way to prevent stroke when atrial fibrillation is newly found. It may help by improving how quickly and consistently stroke-prevention treatment is considered.
Portland, OregonAges 18 years+ - NCT05339048Enrolling by invitation
Study of adults from Colombia’s Caribbean coast
This study follows adults who were born or are from Colombia’s Caribbean coast. The goal is to learn about health patterns in this community, but you would not be able to join if you meet certain medical or disability-related criteria.
Cartagena, Departamento de BolívarAges 18–80 - NCT05332054Enrolling by invitation
Long-term follow-up after prior Caribou treatment
This study checks your health over time after you previously took a Caribou medicine (or got it through a special access program). It helps researchers learn what happens in the longer run after the treatment.
Birmingham, AlabamaAges 18 years+ - NCT05308927Enrolling by invitation
Registry for children with Noonan syndrome on growth hormone
This trial is a real-world registry that collects information about children with Noonan syndrome who are treated with Norditropin (a growth hormone). It helps researchers understand how these children do over time in routine care.
AngersAges Any age - NCT05283850RecruitingPhase 2/Phase 3
Study for certain adult cardiac arrest patients
This trial is for adults who have a specific type of cardiac arrest called PEA when EMS arrives. It tests whether the study approach can improve outcomes after this kind of arrest.
Roanoke, VirginiaAges 18 years+ - NCT05267990Enrolling by invitation
CT calcium scan to prevent heart problems in diabetes
This trial studies whether using a heart CT “calcium score” to guide prevention can lower the chance of major heart disease in people with type 2 diabetes who have other heart risk factors. It may help by targeting prevention more personally, based on your calcium score.
YilanAges 40 years+ - NCT05258422Enrolling by invitationPhase 2
Radiation ablation for recurring heart rhythm tachycardia
This study tests a targeted form of radiation therapy to stop a dangerous, repeat heart rhythm called ventricular tachycardia. It’s for people whose rhythm keeps coming back even after standard treatments like antiarrhythmic medications and prior heart procedure studies.
Montreal, QuebecAges 18 years+ - NCT05254535Enrolling by invitation
Tele-eye screening help for rural clinics with diabetes
This study tests whether adding a structured telehealth program (video eye checks) can improve diabetic eye screening in rural health systems. Your clinic may help the researchers measure changes using shared, de-identified patient data.
Madison, WisconsinAges 18 years+ - NCT05236556Enrolling by invitation
Tracking how providers use oral blood thinners for AF
This study looks at how often and how well doctors use oral blood-thinner medicines for people with atrial fibrillation (AF) or atrial flutter (a related heart rhythm problem). It aims to see whether “provider profiling” (using clinic patterns to guide improvements) can support safer, more consistent use of these medicines.
Jacksonville, FloridaAges 18 years+ - NCT05230134Enrolling by invitation
Nerve block treatment for brain blood vessel spasm after bleeding
This trial looks at a procedure that blocks specific nerves to help prevent or treat blood vessel spasm in the brain after a ruptured brain aneurysm. If you qualify, it may help improve blood flow to the brain during recovery in the ICU.
Stanford, CaliforniaAges 18 years+ - NCT05224635Enrolling by invitation
Study of vascular injuries after trauma in adults
This study follows adults who have been diagnosed with a blood vessel injury after trauma. It aims to better understand these injuries and how they are identified and managed soon after coming to a specific hospital.
Dallas, TexasAges 16 years+ - NCT05208450Enrolling by invitation
A program to help Black adults control high blood pressure
This study tests a community-and-clinic support program to help Black adults lower blood pressure and reduce health care disparities. It looks at what support and engagement works best, especially for people whose blood pressure is still above goal.
New York, New YorkAges 18 years+ - NCT05202977Enrolling by invitation
TAVR valve replacement for older adults with aortic valve narrowing
This trial tests a newer transcatheter (catheter-based) aortic valve replacement device to improve symptoms and safety in older adults with severe aortic stenosis. You may qualify if you’re too high-risk for open-heart surgery and the valve/artery measurements fit the device.
Hefei, AnhuiAges 65 years+ - NCT05166447Enrolling by invitation
Check-in study for people from the Inter99 health survey
This study is a long-term follow-up of people who took part in the Inter99 baseline exam. It involves a 3-hour check-in, and it can help researchers learn how people’s health changes over time.
Glostrup MunicipalityAges 50–82 - NCT05132660Enrolling by invitationEarly Phase 1
Early eye treatment study for diabetic retinopathy
This early-phase study tests a treatment aimed at preventing or slowing early diabetic eye disease in people with mild, early changes. You may be considered if your diabetes is moderately controlled and your eye tests show early warning signs.
Decatur, GeorgiaAges 30–80 - NCT05101746Enrolling by invitationPhase 2/Phase 3
Nitric oxide to protect brain and kidneys in babies during heart surgery
This trial studies whether giving nitric oxide during heart-lung bypass surgery can help protect a baby’s brain and kidneys. If you qualify, the study team will check outcomes after surgery to see if benefits happen compared with usual care.
Nashville, TennesseeAges birth–1 year - NCT05100420Enrolling by invitation
HCM registry and DNA/imaging data collection study
This study collects health records, heart ultrasound (echo), MRI images, and optional DNA testing for people with hypertrophic cardiomyopathy (HCM). It aims to build a large database to better understand HCM and support future research and care.
Edmonton, AlbertaAges Any age - NCT05090540Enrolling by invitation
Less Invasive vs Usual Surgery for Mitral Valve Leaks
This trial compares a less invasive catheter procedure to the standard surgical operation to treat “secondary” leaking of the mitral valve. It may help people with significant valve leak decide which approach works better for reducing symptoms and heart strain.
Saint-DenisAges 18–90 - NCT05074342Enrolling by invitation
Project Open study to improve eye screening for diabetes
This study uses health records to see how to increase eye exam screening for people with diabetes who may be at risk of diabetic retinopathy. It aims to help more people get timely eye checks to prevent vision problems.
Toronto, OntarioaAges 18 years+ - NCT05064891Enrolling by invitation
Ultrasound therapy for shoulder movement after stroke
This trial studies whether using ultrasound on a shoulder nerve (the suprascapular nerve) and guided shoulder movement exercises can improve shoulder motion in people after a stroke. It may help if your biggest problem is pain and limited shoulder movement after stroke.
TaipeiAges 20–80 - NCT05029115Enrolling by invitation
SGLT2 pill study for atrial fibrillation with type 2 diabetes
This trial tests whether an SGLT2 inhibitor pill can help people who have atrial fibrillation (an irregular heartbeat) and type 2 diabetes. You may be eligible if you’re in the right age range, on diabetes pills only, and meet specific heart and lab criteria.
Yangcheon, SeoulAges 20–80 - NCT04933721Enrolling by invitationPhase 3
Continue berotralstat for people with hereditary angioedema
This study lets people who were already taking berotralstat through earlier BioCryst studies keep the treatment going. It looks at safety and ongoing benefit for preventing hereditary angioedema attacks.
OttawaAges 2 years+ - NCT04929457Enrolling by invitation
Screening to detect inherited high cholesterol
This study tests a digital screening method to help identify and diagnose familial hypercholesterolemia, an inherited condition that can cause very high cholesterol. If you participate, you may be invited to complete screening steps to see whether they can find the condition early.
StockholmAges Any age - NCT04926792Enrolling by invitation
Leadless pacemaker registry for patients in Taiwan
This trial is a registry that collects information about people who already received a leadless pacemaker or are planning to get one. It helps doctors better understand how this newer heart device works in everyday care.
TaipeiAges Any age
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,073 recruiting cardiology studies from the U.S. registry right now, out of 15,588 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
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- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.