Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,973 recruiting studies in this area right now.
By phase
- Not applicable7,957
- Phase 2481
- Phase 4480
- Phase 3447
- Phase 1360
- Phase 1/Phase 2162
- Phase 2/Phase 386
Top conditions
- Stroke843
- Heart Failure565
- Hypertension399
- Cardiovascular Diseases390
- Coronary Artery Disease373
- Multiple Myeloma333
- Atrial Fibrillation268
- Ischemic Stroke200
- Atrial Fibrillation (AF)140
- Acute Ischemic Stroke138
- Myocardial Infarction101
- Pulmonary Hypertension100
- Stroke, Ischemic86
- Congenital Heart Disease85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California461
- Alabama197
- Massachusetts183
- Arizona173
- New York161
- Florida145
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,970 total
- NCT07174141Recruiting
Heart risks from newer blood cancer drugs (acalabrutinib or zanubrutinib)
This study looks for early signs of heart problems in people taking newer targeted blood cancer drugs called acalabrutinib or zanubrutinib. By using special blood tests, doctors hope to catch and manage heart issues before they become serious.
DijonAges 18 years+ - NCT03518099Recruiting
Testing blood signals after sudden bowel blood flow injury
This study is looking for signs in the body (called biomarkers) after sudden loss of blood flow to the intestines. It involves getting a CT scan to check what is happening in the abdomen so the researchers can see which signals match intestinal injury.
ClichyAges 18 years+ - NCT06772025Recruiting
Understanding kidney injury after heart surgery with heart-lung machine
This study looks at why some people develop kidney damage after heart surgery that uses a heart-lung machine. It aims to help doctors better predict and prevent this complication.
Bad Oeynhausen, North Rhine-WestphaliaAges 18 years+ - NCT07159087Enrolling by invitation
New drug balloon for re-narrowed stents
This trial tests a new drug-coated balloon (Genoss SCB) versus an existing one (SeQuent Please NEO) for people whose heart stents have re-narrowed. It aims to see which balloon better keeps the artery open.
Gyeonggi-doAges 19 years+ - NCT03657524Recruiting
Ultrasound heart imaging to help predict trouble weaning off a ventilator
This study uses a special ultrasound of the heart to help predict whether you might fail a trial of breathing on your own after being on a breathing machine. If the test can predict trouble early, clinicians may choose safer weaning plans.
MarseilleAges 18 years+ - NCT07164638Enrolling by invitation
Predicting fluid overload during prostate surgery
This study uses ultrasound to check for fluid overload in men having prostate surgery with spinal anesthesia. The goal is to see which ultrasound method works best to prevent complications.
TantaAges Any age - NCT07130409Recruiting
Heart imaging after emergency angioplasty for first heart attack
This study uses advanced heart scans (MRI) before and after a common artery-opening procedure to see how the heart heals. It only includes people having their first heart attack who get emergency treatment with a stent.
Qingdao, ShandongAges 18–80 - NCT05884190Recruiting
Help for early high blood pressure after childbirth
This study tests a “trauma-informed” approach to detect and manage high blood pressure soon after delivery. It may help you get faster support and safer treatment during the early postpartum period.
New Haven, ConnecticutAges 18 years+ - NCT07159074RecruitingPhase 2
Testing tilmanocept for heart inflammation in sarcoidosis
This study tests whether a tracing agent called tilmanocept can help doctors see inflammation in the heart caused by sarcoidosis. It may provide a new way to diagnose and monitor cardiac sarcoidosis without invasive procedures.
Durham, North CarolinaAges 18 years+ - NCT04391465Recruiting
Blood flow and heart rate during a heart procedure study
This study looks at how changes in blood flow in the brain relate to heart rate during a specific heart rhythm procedure. It may help doctors better understand how the body’s brain and heart responses connect during temporary pacing.
Calgary, AlbertaAges 18–70 - NCT04450953RecruitingPhase 3
Eplerenone to slow blood vessel damage after kidney transplant
This trial tests whether eplerenone can slow the progression of blood vessel (vasculature) problems in people who have had a kidney transplant. You may be eligible if you are older, stable on your transplant medicines, and have higher peripheral artery blood pressure readings.
Vandœuvre-lès-NancyAges 50 years+ - NCT06196086Recruiting
Measuring heart stiffness in heart failure with normal pumping
This study uses a special ultrasound technique to check how stiff the heart muscle is in people with heart failure who have a normal pumping ability (HFpEF). It aims to better understand heart stiffness to help diagnose and manage this condition.
Jinan, ShandongAges 18–80 - NCT03672760Recruiting
Breathing training app for heart vessel stiffness and stress signals
This study tests whether an inspiratory (breathing-in) muscle training program using the CardioBreath app can improve heart blood-vessel stiffness and “stress/autonomic” signaling. It targets people with a specific hormone pattern and activity level, while avoiding several common health conditions that could affect safety or results.
Porto Alegre, Rio Grande do SulAges 45–65 - NCT06464263Recruiting
Dexmedetomidine vs. midazolam-fentanyl for sedation
This trial compares two sedation and pain relief medicine combinations (dexmedetomidine vs. midazolam-fentanyl) to see which works better for people having planned heart valve surgery.
CairoAges 21–50 - NCT04476901RecruitingPhase 2
Study of donor stem cell treatment for non-ischemic heart failure
This Phase 2 trial tests whether donor “MSC” cells can improve heart function in people with non-ischemic dilated cardiomyopathy and reduced pumping strength. You may be eligible if your condition is already treated with standard heart medicines and you can safely undergo a heart catheterization and follow-up testing.
Stanford, CaliforniaAges 18–80 - NCT06475105RecruitingPhase 4
Acetazolamide and Furosemide for Acute Heart Failure
This trial tests whether adding an oral water pill (acetazolamide) to standard IV furosemide helps people with acute heart failure who have fluid overload. It aims to see if the combination improves outcomes better than furosemide alone.
Semarang, Central JavaAges 18 years+ - NCT03389542Recruiting
Early mitral valve repair versus watchful waiting
This trial compares doing mitral valve repair early versus closely monitoring without surgery in people who have severe leakage but no symptoms. It aims to see whether early repair helps prevent future heart problems.
AmiensAges 18–75 - NCT06193954Recruiting
Vibrating guidewire for chronic heart artery blockages
This trial tests a special vibrating guidewire to help open heart arteries that have been completely blocked for a long time, when standard wires have failed. It may help you if you have a stubborn blockage requiring a gentle approach.
Atlanta, GeorgiaAges 18 years+ - NCT02670408Recruiting
Microarrays test in heart transplant care
This study checks how special lab tests on heart tissue samples can help guide diagnosis and treatment for people with a heart transplant. You may be eligible if you already need a heart tissue biopsy for a clinical reason and can provide consent.
Los Angeles, CaliforniaAges 18 years+ - NCT06492980Recruiting
Stent graft for acute type I aortic dissection repair
This trial tests a special stent graft for people with a sudden tear in the inner layer of the aorta (type I aortic dissection) that needs urgent repair. It aims to see if the device can help treat the condition safely.
Fuzhou, FujianAges 20–65 - NCT07110818Recruiting
Non-ischemic Cardiomyopathy Registry and Biobank
This registry study collects information, blood samples, and MRI images from people with non-ischemic cardiomyopathy (a heart muscle disease not caused by blocked arteries). By joining, you help researchers better understand the condition and find new ways to diagnose and treat it.
Montreal, QuebecAges Any age - NCT03002272Recruiting
Long-term follow-up after TAVR or surgical valve replacement
This study checks how well an aortic valve replacement works many years after the procedure. It may help doctors understand long-term valve function and identify people who might need closer monitoring.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06506968Recruiting
Ergonomics study for heart lab staff
This study looks at how ergonomics (the way your body moves and feels at work) affect staff in the heart catheterization lab. You might join if you work there and are willing to wear special sensors to track your movements.
Boston, MassachusettsAges 21 years+ - NCT06500351Recruiting
Postpartum hypertension gene and aging study
This study looks at two things in women with postpartum hypertension (high blood pressure after giving birth). It tests a gene called Renalase and measures the length of telomeres (a marker of cell aging) to see if they are linked to this condition.
SohagAges 18–45
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,973 recruiting cardiology studies from the U.S. registry right now, out of 15,205 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
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- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.