Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,609 recruiting studies in this area right now.
By phase
- Not applicable7,632
- Phase 4472
- Phase 2469
- Phase 3439
- Phase 1350
- Phase 1/Phase 2160
- Phase 2/Phase 387
Top conditions
- Stroke797
- Heart Failure534
- Hypertension388
- Cardiovascular Diseases373
- Coronary Artery Disease363
- Multiple Myeloma327
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction97
- Congenital Heart Disease84
- Peripheral Arterial Disease79
- Stroke, Ischemic78
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital68
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California453
- Alabama196
- Arizona181
- Massachusetts173
- New York168
- Florida140
- Texas122
- Maryland118
- Minnesota117
- Illinois112
Recruiting studies9,609 total
- NCT07822997Recruiting
Quality of Life Questionnaire for Pulmonary Hypertension in Brazil
This study is testing a questionnaire (EMPHASIS-10) to measure quality of life in people with pulmonary hypertension. The goal is to adapt it for Brazilian Portuguese speakers so doctors can better understand how the disease affects daily life.
Porto AlegreAges 18 years+ - NCT07817316Recruiting
Brain training to improve attention after brain injury
This study tests two brain-training methods, neurofeedback and transcranial random noise stimulation (tRNS), to see if they can help improve attention problems in people who have had a brain injury. It may help people who have difficulty focusing or staying on task after their injury.
Valencia, ValenciaAges 18–85 - NCT07824921Enrolling by invitation
Oral microbiome in aorta aneurysm and carotid atherosclerosis
This study looks at how bacteria in your mouth might be linked to the health of your blood vessels. It may help doctors understand why some people get aneurysms or blocked arteries, and could lead to better ways to prevent or treat these conditions.
BudapestAges 18–110 - NCT07824050Recruiting
Studying dangerous heart rhythms after a heart attack
This study looks at people who had a heart attack or cardiac arrest to find out which dangerous heart rhythms can happen afterward. The goal is to improve care and prevent future problems.
Eindhoven, North BrabantAges 18 years+ - NCT07824297Recruiting
Cognitive outcomes after brain blood vessel malformation treatment
This trial tests whether a minimally invasive procedure to block a specific type of abnormal connection between brain blood vessels can help preserve or improve memory and thinking. It is being studied in people who have not yet had bleeding from this condition.
BolognaAges 18–99 - NCT05994664Recruiting
Heart Coherence Training for Vascular Ehlers-Danlos
This study tests whether a breathing and heart-rate training program (called Heart Coherence Training) can help people with Vascular Ehlers-Danlos syndrome feel better. It's done from home using your phone and a computer or tablet.
Houston, TexasAges 12–45 - NCT06446271Recruiting
Biomarkers in Scottish Cardiomyopathy Registry
This study looks for signs of heart muscle disease (cardiomyopathy) in people who have certain genetic changes. It aims to find better ways to monitor and treat the condition.
GlasgowAges 10 years+ - NCT03674788Recruiting
Heart valve patients getting a catheter procedure
This is a registry that follows people who are having a catheter-based treatment for a heart valve problem. It helps doctors understand how these procedures work in real life and may improve future care.
LeuvenAges Any age - NCT06481137Recruiting
Can heart electrical problems after TAVI get better?
This study looks at whether electrical problems in the heart that appear after a TAVI valve replacement can go away on their own. It will help doctors decide which patients might need a pacemaker and which might get better without one.
L'Hospitalet de Llobregat, BarcelonaAges 18 years+ - NCT02445534Recruiting
Registry for cell therapy in non-ischemic dilated heart muscle disease
This is a research registry that follows people with non-ischemic dilated cardiomyopathy (a weakened heart muscle) who are already on the right medications. It helps doctors better understand how cell-based therapy and related care affect heart function over time.
LjubljanaAges 18–65 - NCT05663281Recruiting
Imaging treatment plan for blocked brain or neck arteries
This study uses special MRI “vessel wall” imaging to better understand blocked arteries in the brain or neck, confirmed on a scan. It aims to help analyze imaging findings to guide treatment decisions and reduce problems from artery blockage.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05898542Recruiting
Nature-based therapy for stroke recovery in rehab wards
This trial studies whether nature-based activities (like time outdoors or nature-focused programs) can improve recovery after a stroke. It’s aimed at people who are currently in a stroke rehabilitation setting soon after their stroke.
LahtiAges 18 years+ - NCT05677607Recruiting
Study of brain artery narrowing and small-vessel disease
This study looks at how two types of blood vessel problems in the brain affect each other over time. It may help researchers better understand what to watch for and potentially how to improve outcomes.
Beijing, Beijing MunicipalityAges 30 years+ - NCT06486233Recruiting
Early invasive treatment for elderly heart attack patients
This trial tests whether early invasive treatment (like stenting) is safe and effective for patients 60 or older who have a certain type of heart attack called high-risk non-ST-segment elevation acute coronary syndrome. The goal is to see if this approach improves outcomes for older adults.
Ho Chi Minh CityAges 60 years+ - NCT06374355Recruiting
Semibranch Stentgraft Registry Study
This study looks back at medical records of people who have already received a semibranch stentgraft. It helps doctors learn more about how well the stentgraft works and how people recover after treatment.
MünsterAges 18 years+ - NCT06487052Recruiting
Catheter-based clot-dissolving drug for intermediate-high risk pulmonary embolism
This trial tests whether a standard procedure using a catheter to deliver clot-dissolving medicine directly into the lung artery works well for people with a serious but not immediately life-threatening blood clot in the lungs (pulmonary embolism). It aims to improve heart function and reduce long-term complications.
Saint PetersburgAges 18 years+ - NCT06487130Recruiting
Australia menopause registry study
This study is building a registry to better understand and support Australians going through perimenopause or menopause. By joining, you help researchers learn about the experiences and needs of people in this stage of life.
AdelaideAges 18 years+ - NCT06489080Recruiting
Heart attack follow-up study on survival and health
This study looks at how people with heart attacks do over time, including their survival and any heart-related events. It helps doctors understand more about the condition and how to improve care.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05636787RecruitingPhase 2
Treosulfan chemo for myeloma before stem cell transplant
This trial tests whether the chemotherapy medicine treosulfan (Trecondi® Ideogen) works well and is safe for people with myeloma who are moving on to high-dose chemotherapy plus their own stem cell transplant. It may help strengthen the transplant “conditioning” treatment before the transplant.
BernAges 18–75 - NCT07810439Recruiting
Blood test for preeclampsia during pregnancy
This study is testing a new blood test that might help doctors quickly and safely identify preeclampsia, a serious pregnancy condition. If you're at risk, this test could help you get the right care earlier.
Harare, HarareAges 18–50 - NCT07815886Recruiting
Benralizumab for EGPA: a real-world study
This study looks at how well benralizumab (Fasenra) works for people with EGPA, a rare disease that causes inflammation in blood vessels and can affect the lungs, skin, and nerves. By tracking people already on this treatment, researchers hope to learn more about its long-term effectiveness.
Florence, ItalyAges 18 years+ - NCT07814222Recruiting
A folate-based PET scan for suspected heart inflammation or infection
This trial tests a new imaging tracer called folate PET to see if it can help diagnose two heart conditions: cardiac sarcoidosis (inflammation in the heart) and infective endocarditis (infection on heart valves). If successful, it could offer a more accurate and targeted way to spot these problems early.
TurkuAges 18 years+ - NCT07809516Recruiting
Pedal pump for leg swelling
This trial tests a device called a 'pedal pump' that helps move fluid out of your legs to reduce swelling. It may help if you have fluid buildup from conditions like heart failure or kidney disease.
Tulsa, OklahomaAges 18 years+ - NCT07816029Recruiting
Closing a heart pouch to prevent stroke in atrial fibrillation
This study tests a device and procedure to close off a small pouch in the heart (left atrial appendage) where blood clots can form in people with atrial fibrillation. The goal is to reduce the risk of stroke, possibly lowering the need for long-term blood thinners.
PragueAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,609 recruiting cardiology studies from the U.S. registry right now, out of 14,617 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.