Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,609 recruiting studies in this area right now.
By phase
- Not applicable7,632
- Phase 4472
- Phase 2469
- Phase 3439
- Phase 1350
- Phase 1/Phase 2160
- Phase 2/Phase 387
Top conditions
- Stroke797
- Heart Failure534
- Hypertension388
- Cardiovascular Diseases373
- Coronary Artery Disease363
- Multiple Myeloma327
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction97
- Congenital Heart Disease84
- Peripheral Arterial Disease79
- Stroke, Ischemic78
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital68
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California453
- Alabama196
- Arizona181
- Massachusetts173
- New York168
- Florida140
- Texas122
- Maryland118
- Minnesota117
- Illinois112
Recruiting studies9,609 total
- NCT05280028Recruiting
Hormone treatment for overactive bladder and mood symptoms
This trial studies whether hormone treatment can improve overactive bladder symptoms, sexual well-being, mood (depressive symptoms), and body “autonomic” function (automatic body functions like heart rate and sweating) in post-menopausal women. It may help by targeting menopausal changes that can affect these symptoms.
Banqiao District, New TaipeiAges 20 years+ - NCT06462768Recruiting
Study of immune cell activity in systemic sclerosis
This study looks at a specific type of immune cell activity (called neutrophil extracellular traps) in the blood of people with systemic sclerosis, other connective tissue diseases, and healthy volunteers. It aims to understand how these cells may be involved in the disease and could lead to better treatments.
ReimsAges 18 years+ - NCT06462274Recruiting
Blood and brain markers for brain bleed recovery
This study looks for markers in your blood and brain scans that may help doctors better understand and predict outcomes after a spontaneous brain bleed. It is for people with high blood pressure who have had a bleed within the last three days.
Chongqing, Chongqing MunicipalityAges 18–80 - NCT03582293RecruitingPhase 3
Tranexamic acid to prevent worsening chronic brain bleed
This Phase 3 study tests whether tranexamic acid (a medicine that helps blood clot) can stop a chronic subdural hematoma from getting worse. It’s for people diagnosed by CT who are being treated without surgery at first.
AmsterdamAges 50 years+ - NCT05346068Recruiting
Compare two balloon types for calcium-heavy blocked heart arteries
This trial studies whether one type of balloon works better than another for treating badly calcified (hardened) coronary artery blockages. If you qualify, you would be randomly assigned to get the tested balloon treatment during your heart procedure.
LucerneAges 18 years+ - NCT06459934Recruiting
Heart and cardiovascular disease study
This study looks at the health outcomes of people with common heart conditions like coronary artery disease, high blood pressure, heart failure, or cardiomyopathy. It may help researchers understand how these conditions progress and how to better manage them.
Ürümqi, XinjiangAges 18–80 - NCT04847752Recruiting
Predicting outcomes after stroke from artery plaque
This study looks at factors that can help predict recovery and risk after an ischemic stroke caused by plaque buildup in a major artery. It may help doctors better forecast prognosis and tailor follow-up care for people like you.
WuhanAges Up to 80 years - NCT06465758Recruiting
Stroke recovery study
This study is for people who have had a stroke and are in the early recovery phase. It looks at how well patients recover, with a focus on arm and hand movement, to help guide future care.
MilanAges 18 years+ - NCT06466772Recruiting
Personalized walking therapy after stroke
This study tests a new therapy that uses personalized electrical stimulation to help people who have trouble walking after a stroke or brain bleed. It aims to improve how your brain and muscles work together for better walking.
Zurich, Canton of ZurichAges 18 years+ - NCT07827105Enrolling by invitation
AI heart test for undiagnosed aortic stenosis
This study uses an artificial intelligence (AI) tool to analyze electrocardiograms (ECGs, which record the heart's electrical activity) to find people who may have a heart valve condition called aortic stenosis, which can make the heart work harder. The goal is to help detect this condition earlier in people who haven't been diagnosed yet.
Orange, CaliforniaAges 65 years+ - NCT07828210RecruitingPhase 4
Mild to moderate stroke recovery study
This study tests a daily supplement called NeuroAiD to see if it helps people recover after a mild or moderate stroke. It looks at how well patients feel and function in their daily life during recovery.
Ho Chi Minh CityAges 18–80 - NCT06463717Recruiting
Stem cell transplant timing for multiple myeloma with no cancer cells left
This trial looks at people with newly diagnosed multiple myeloma who have no detectable cancer cells after initial treatment. It aims to see if these patients can do well without a stem cell transplant or with a delayed one, reducing unnecessary side effects.
Hangzhou, ZhejiangAges 18–70 - NCT06470646Recruiting
Endovascular treatment for dialysis graft problems
This trial studies a procedure to open up blocked or narrowed areas in the plastic tube (graft) used for dialysis. It aims to see if the procedure works well and if it is cost-effective for patients who have trouble completing dialysis because of graft issues.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT07831252Recruiting
Blood pressure and oxygen levels during heart surgery
This study looks at how blood pressure changes during the start of open heart surgery and whether it affects oxygen levels in body tissues. It may help doctors better manage blood pressure during surgery to keep patients safe.
Istanbul, SultangaziAges 18–90 - NCT07832578RecruitingEarly Phase 1
Aspirin with or without rivaroxaban for severe leg artery disease
This trial compares two ways to prevent blood clots in people with severe leg blockage (chronic limb-threatening ischemia) who are not having surgery. It tests aspirin alone versus a newer blood thinner (rivaroxaban) plus aspirin, to see which works better in preventing complications.
Lahore, Punjab ProvinceAges 40–70 - NCT07826832Recruiting
One-hand versus two-hand training for stroke recovery
This study compares learning arm movements with one hand versus both hands to see which method helps stroke patients recover better. It may help you improve arm function after a stroke.
Yvoir, NamurAges 40–90 - NCT07829887Recruiting
Measuring brain oxygen after cardiac arrest
This study tests a device that measures oxygen levels in the brain during recovery from cardiac arrest. It aims to see if monitoring brain oxygen helps doctors make better treatment decisions after the heart restarts.
Calgary, AlbertaAges Any age - NCT07830888Recruiting
Mitral valve prolapse rhythm risk study
This study looks at people with mitral valve prolapse who also have rhythm problems like extra beats or fast heart rhythms. The goal is to better understand risk and improve care.
OsloAges Any age - NCT07827287Enrolling by invitation
Closure device for heart procedures through leg vein
This trial tests a device that helps close the puncture hole in your leg vein after a heart procedure, which may reduce bleeding and help you recover faster.
SeoulAges 19 years+ - NCT07826845Recruiting
Body donation for people with HHT
This study asks people with HHT (a genetic condition that causes abnormal blood vessels) to consider donating their body after death to help medical research. It aims to learn more about HHT by studying donated tissues.
Essen, North Rhine-WestphaliaAges 18 years+ - NCT07829380Recruiting
Heart and brain health study
This study looks at how heart health and brain health are connected. It may help improve thinking and memory in people with mild memory problems.
SingaporeAges 21–99 - NCT07829705RecruitingPhase 2
Amyloid PET scan to measure treatment response in AL cardiac amyloidosis
This study uses an amyloid PET/CT scan to see how well first-line treatment is working in people with AL cardiac amyloidosis, a condition where abnormal proteins build up in the heart. The scan may help doctors better understand and monitor the disease.
BeijingAges 18 years+ - NCT07829003Enrolling by invitation
Step test to measure fitness in healthy adults
This study tests a new step-based exercise test to see if it works as well as a standard bike test for measuring fitness and breathing. If you are a healthy adult, you might join to help validate this simpler test.
EdinburghAges 18–55 - NCT07827560Recruiting
Acupressure for better sleep in older adults with high blood pressure
This study tests whether acupressure (applying pressure to certain points on the body) can help improve sleep in older adults who have both high blood pressure and trouble sleeping. It aims to find a drug-free way to reduce insomnia and potentially improve overall well-being.
Hanoi, Son TayAges 60 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,609 recruiting cardiology studies from the U.S. registry right now, out of 14,617 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.