Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,976 recruiting studies in this area right now.
By phase
- Not applicable7,959
- Phase 2483
- Phase 4479
- Phase 3447
- Phase 1361
- Phase 1/Phase 2161
- Phase 2/Phase 386
Top conditions
- Stroke841
- Heart Failure567
- Hypertension401
- Cardiovascular Diseases390
- Coronary Artery Disease372
- Multiple Myeloma334
- Atrial Fibrillation268
- Ischemic Stroke201
- Atrial Fibrillation (AF)140
- Acute Ischemic Stroke137
- Myocardial Infarction102
- Pulmonary Hypertension100
- Congenital Heart Disease85
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California460
- Alabama197
- Massachusetts183
- Arizona174
- New York161
- Florida145
- Maryland120
- Illinois119
- Minnesota119
- Texas118
Recruiting studies9,973 total
- NCT07780448Recruiting
Learning to recognize heart rhythms for new ICU nurses
This study tests a teaching method that uses real-life cases to help new nurses in intensive care units learn how to identify heart rhythm problems. It might improve their skills in reading heart monitors, which can be important for patient safety.
Istanbul, KartalAges 18 years+ - NCT07338461Recruiting
High-resolution eye imaging study for healthy and eye disease volunteers
This study uses a special, high-resolution camera to take detailed pictures of the back of the eye. It is testing the camera's ability to see changes in the retina for people who are healthy or have age-related macular degeneration, diabetic retinopathy, or other conditions that affect autofluorescence patterns.
MilanAges 18 years+ - NCT07240714Enrolling by invitation
Web-based support for cardiac arrest survivors
This study tests a web-based support program for people who have survived a cardiac arrest. It aims to help you with recovery by providing online tools and information.
GothenburgAges 18 years+ - NCT07655505Recruiting
Robotic mitral valve repair with force feedback tools
This trial tests a new robotic tool that gives surgeons a sense of touch during mitral valve repair. If you have a severe leak in your mitral valve and are a good candidate for minimally invasive surgery, this study may offer a way to fix it using the da Vinci robot.
Atlanta, GeorgiaAges 22 years+ - NCT07010159RecruitingPhase 2/Phase 3
Study of KPL-387 for returning pericarditis
This study tests a new medicine, KPL-387, for people whose pericarditis keeps coming back despite standard treatments. It aims to see if this medicine can reduce flare-ups and help you feel better.
Gilbert, ArizonaAges 18–80 - NCT07780942Recruiting
Testing a smartwatch for detecting heart attacks in people with chest pain
This study is testing how well a smartwatch can detect a specific type of heart attack (STEMI) in people who come to the hospital with chest pain. It aims to see if the smartwatch's ECG feature is accurate compared to standard hospital tests.
Cartagena, MurciaAges 18 years+ - NCT06742723RecruitingPhase 3
Study of baxdrostat and dapagliflozin for kidney disease and high blood pressure
This trial tests if combining baxdrostat with dapagliflozin helps protect kidney function and reduce heart risks in people with chronic kidney disease and high blood pressure. It's for adults who are already taking standard blood pressure medications.
Fairhope, AlabamaAges 18 years+ - NCT07719660Recruiting
Wearable blood pressure monitor comparison study
This study compares a wearable blood pressure monitor to standard measurements. It needs people whose arm can be used for a cuff and who can give consent, and some participants are in the ICU.
Dresden, SaxonyAges 21–85 - NCT03876223Recruiting
Testing imaging to study heart symptoms without blocked arteries
This trial studies people who have heart-related symptoms but do not have clear blocked heart arteries, using special heart imaging. It may help researchers better understand early forms of heart weakness (with preserved pumping function) and improve how these conditions are diagnosed.
Los Angeles, CaliforniaAges 18 years+ - NCT06388421Recruiting
PH-ILD patient registry: tracking real-world outcomes
This study tracks people with both lung scarring and high blood pressure in the lungs (Group 3 PH-ILD) to better understand the disease and how treatments like Tyvaso work in real life. It may help you and your doctor make more informed decisions about your care.
Birmingham, AlabamaAges 18 years+ - NCT07188285Enrolling by invitation
Immune system study for active autoimmune diseases
This study uses a blood test called mass spectrometry to look at the immune system in people with active autoimmune diseases. It aims to find patterns that could help doctors better understand and treat these conditions.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06945809Recruiting
Sealing distal tears after aortic dissection repair
This trial tests a new device (WeFlow-EndoPatch) to seal small tears in the aorta after previous dissection repair. It may be an option if you have 1 or 2 small tears in your descending aorta and are generally healthy enough for a catheter procedure.
Beijing, Beijing MunicipalityAges 18–80 - NCT07435662Recruiting
Improving heart failure care in Denver
This study aims to improve heart failure treatment for people who have limited access to care in Denver. If you have heart failure with reduced pumping ability and are a patient in the Denver Health system, this trial may help find better ways to manage your condition.
Denver, ColoradoAges 18 years+ - NCT07532174Recruiting
Blood-Cleaning Device During Heart Surgery
This trial tests a special blood-filtering device (Efferon LPS) used during heart surgery to reduce inflammation and improve recovery. The device removes harmful substances from your blood during the operation.
BarnaulAges 18 years+ - NCT07096934RecruitingPhase 1/Phase 2
Testing a new cell treatment for stubborn diabetic foot ulcers
This trial tests a new treatment using special skin cells grown into tiny spheres (spheroids) to help heal diabetic foot ulcers that have not healed with standard care. It aims to see if this treatment is safe and works better than usual care.
Coffs Harbour, New South WalesAges 18–80 - NCT07276711Recruiting
Protecting brain during TAVR with EmStop device
This trial tests a new device (EmStop) that helps protect your brain during TAVR (a type of heart valve replacement). The device is placed in arteries to catch any debris that might break loose during the procedure, potentially reducing the risk of stroke.
Thousand Oaks, CaliforniaAges 22 years+ - NCT04647240RecruitingPhase 2
Drug trial for stubborn leg ulcers that won’t heal
This Phase 2 trial tests MTX-001 to help heal “venous stasis ulcers,” which are open sores caused by weak leg vein circulation. It may be an option if you’ve tried standard high-compression care for weeks and your ulcer is still not healing.
Tucson, ArizonaAges 18 years+ - NCT07690436Recruiting
Eye imaging for detecting a type of heart disease
This study uses retinal imaging (pictures of the back of the eye) and OCT scans to look for signs of a specific heart condition called transthyretin amyloid cardiomyopathy (ATTR-CM). It may help doctors find this condition with an eye exam instead of more invasive tests.
Palo Alto, CaliforniaAges 18 years+ - NCT06059638Recruiting
Pacemaker pacing for blood pressure control
This study tests whether adjusting the timing of a pacemaker can help lower blood pressure in people who already have or need a pacemaker. It could be an option for those whose blood pressure is not well controlled with medication.
Scottsdale, ArizonaAges 18 years+ - NCT07628283Recruiting
Telemedicine stroke prevention program for rural elderly adults
This study tests whether using telemedicine (remote health technology) combined with care at a local village clinic can better prevent strokes and manage stroke risk in older adults living in rural areas. Participants will receive ongoing health monitoring and support tailored to their stroke risk factors.
Suqian, JiangsuAges 65 years+ - NCT07651631Recruiting
Brain Bleeding Surgery Registry and Treatment Study
This study tracks patients who have had sudden, severe bleeding in the brain and received minimally invasive surgery (a less-invasive surgical approach) to treat it. Researchers want to understand outcomes and improve treatment for this serious condition.
Atlanta, GeorgiaAges 18 years+ - NCT06957587Recruiting
Using Ultrasound and AI to Measure Blood Volume
This study tests if an artificial intelligence (AI) program can accurately measure how much blood you have in your body using ultrasound pictures. It may help doctors better manage fluids during surgery or illness.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06952608RecruitingPhase 4
Ciprofol for blood pressure stability in older adults on heart medications
This study tests whether ciprofol, a newer sedative, can help prevent low blood pressure during surgery in older patients who are already taking medications for high blood pressure or heart failure (called RAS inhibitors). It may be a good option if you're 65 or older, on these medications for more than 3 months, and having abdominal surgery lasting over 2 hours.
Hangzhou, ZhejiangAges 65 years+ - NCT06885073Recruiting
A new way to check vein pressure in children without needles
This trial tests a new way to measure pressure inside a major vein in the chest without needing to stick any needles. It might be an option for children and young adults up to age 21 who already have a central line or are getting a heart catheter.
Washington D.C., District of ColumbiaAges Up to 21 years
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,976 recruiting cardiology studies from the U.S. registry right now, out of 15,179 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.