Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,609 recruiting studies in this area right now.
By phase
- Not applicable7,632
- Phase 4472
- Phase 2469
- Phase 3439
- Phase 1350
- Phase 1/Phase 2160
- Phase 2/Phase 387
Top conditions
- Stroke797
- Heart Failure534
- Hypertension388
- Cardiovascular Diseases373
- Coronary Artery Disease363
- Multiple Myeloma327
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction97
- Congenital Heart Disease84
- Peripheral Arterial Disease79
- Stroke, Ischemic78
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital68
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California453
- Alabama196
- Arizona181
- Massachusetts173
- New York168
- Florida140
- Texas122
- Maryland118
- Minnesota117
- Illinois112
Recruiting studies9,609 total
- NCT02420067Recruiting
Screening for inner-ear tumors in people with Von Hippel-Lindau
This trial focuses on checking whether a specific inner-ear tumor (called an endolymphatic sac tumor) can be found earlier in people with Von Hippel-Lindau (vHL) disease. It may help doctors detect problems sooner so you can discuss treatment options earlier, if needed.
Copenhagen, Copenhagen NAges 15 years+ - NCT03152630Recruiting
Vascular dementia check-up and risk diagnosis study
This study aims to find early ways to diagnose “vascular dementia,” which happens when blood vessel problems affect thinking and memory. It may help by testing how well certain health risk factors and medical information can predict who might be developing it.
TaipeiAges 65 years+ - NCT02608996RecruitingPhase 1/Phase 2
Nesiritide test for hard-to-control blood pressure
This Phase 1/2 study tests nesiritide, a medicine that affects blood vessels and heart strain, to see if it can improve blood pressure control in people with hypertension. It’s mainly for people whose blood pressure stays high even during the day despite medication.
OsloAges 18–79 - NCT02488876Recruiting
Banking heart tissue samples after cardiac surgery
This study collects tissue samples from people who are having heart surgery and stores them in a database to better understand the body’s inflammatory (immune) response after surgery. Your participation may help researchers learn why inflammation happens and how to improve care after surgery.
Aachen, North Rhine-WestphaliaAges Any age - NCT03272620Recruiting
Emergency atrial fibrillation patients invited to study
This study includes people who have atrial fibrillation and are seen in the emergency department. It aims to learn from emergency care and may help improve how atrial fibrillation is managed in the ER.
ViennaAges 18 years+ - NCT03416166Recruiting
Registry for people getting a heart valve procedure
This study collects information about people who are having a transcatheter tricuspid valve procedure (a heart valve treatment done through catheters rather than open-heart surgery). It may help doctors understand safety and outcomes better over time.
ZurichAges 18–99 - NCT03398850Recruiting
Study of coronary artery dissection cases in Brazil
This trial looks at patients who had a specific heart blood-vessel problem called spontaneous coronary artery dissection (SCAD). Doctors are reviewing confirmed cases to better understand how SCAD is identified in real-world patients.
São Paulo, São PauloAges Any age - NCT03394313Recruiting
Registry study for people with new heart disease and type 2 diabetes
This study records health information to understand how type 2 diabetes and newly diagnosed heart disease affect people over time. It may help doctors learn what to watch for and how to plan care, though it is mainly an observational registry.
DohaAges 18 years+ - NCT03385122Recruiting
Study of environment and heart health in Corinthia
This study looks at how people’s surroundings in the Corinthia region may relate to heart (cardiovascular) health. It will include adults from the region who can consent to participate.
Athens, AtticaAges 40 years+ - NCT03217656Recruiting
Jiaxing birth follow-up study for pregnant families
This study enrolls pregnant women in the Jiaxing area and follows them during pregnancy and after delivery to learn about mothers and babies. If you plan to stay involved through birth and follow-up, this may help researchers understand pregnancy and early childhood outcomes.
Hangzhou, ZhejiangAges Any age - NCT03393169Recruiting
Tracking complications after heart surgery in adults
This study looks at how often and why complications happen after heart surgery, using information from the hospital stay. It may help improve care by understanding postoperative risks and outcomes.
ParisAges 18 years+ - NCT02696135Recruiting
Study of Chinese people with hypertrophic cardiomyopathy
This study looks at people with hypertrophic cardiomyopathy (HCM), a heart condition that causes part of the heart muscle to thicken for no clear reason. It will compare how HCM is identified and studied, which may help doctors better understand and manage the condition in Chinese patients.
Beijing, Beijing MunicipalityAges Any age - NCT03562169RecruitingPhase 3
Ixazomib with your own stem cell transplant for relapsed myeloma
This trial studies whether adding ixazomib (an oral drug) to a transplant using your own stem cells can control relapsed multiple myeloma better. It may help by strengthening anti-myeloma treatment after the transplant, aiming to delay disease progression.
AberdeenAges 18 years+ - NCT03594318Recruiting
Registry for adults treated in ICU after cardiac arrest
This trial is a registry, which means the researchers collect information about people who were treated in an intensive care unit after a cardiac arrest. It may help improve understanding of outcomes and care, which can guide future treatment.
Le ChesnayAges 18 years+ - NCT03600662Recruiting
Heart valve reconstruction using your own tissue
This trial studies a surgery to repair the aortic valve using tissue taken from your body. It may help people with significant valve problems, by testing whether this reconstruction approach works and is safe.
Munich, BavariaAges 50 years+ - NCT03569735Recruiting
Elderly health survey in Nanshan, Shenzhen
This study follows people age 65 and older in Nanshan to learn about health over time using surveys and health samples. It may help researchers understand what supports healthy aging in the community.
Shenzhen, GuangdongAges 65 years+ - NCT03195556Recruiting
Test ultrasound contrast to improve blood flow in legs
This study checks whether using a special ultrasound with contrast can improve blood flow in people with peripheral artery disease (PAD). If you have leg circulation problems, it may help doctors measure and potentially enhance how well blood reaches your limb.
Portland, OregonAges 19–99 - NCT04025450RecruitingPhase 1/Phase 2
Tested stronger combo for high-risk myeloma patients
This early-phase study compares two drug combinations—chidamide plus VRD versus VRD alone—to see which works better for primary high-risk multiple myeloma. The goal is to improve response while closely monitoring side effects and heart/lung safety.
Suzhou, JiangsuAges 18–80 - NCT03781531Recruiting
Blood tests to find hidden cancer after a blood clot
This study looks for “biomarkers,” or blood signs, that may help detect hidden (occult) cancer in people who recently had a blood clot in the leg or a lung clot. It may help doctors catch cancer earlier by improving detection after venous thromboembolism.
StockholmAges 18 years+ - NCT03821051Recruiting
Registry for heartbeat rhythm problems from structural heart disease
This is a registry that collects information about people with certain dangerous heartbeat rhythm problems caused by structural (anatomical) heart diseases. It may help researchers understand patterns and risks, and improve how these conditions are studied and managed.
Beijing, Beijing MunicipalityAges Any age - NCT03772275Recruiting
Tests new blood markers in chronic heart failure patients
This study looks at whether certain new blood tests (biomarkers) can help doctors learn more about chronic heart failure. You might be asked for blood samples and health information, and the results could improve how heart failure is understood in the future.
Tanta, ElgharbiaAges 18–75 - NCT03823547Recruiting
Research study for adults with ACS
This study is for adults who are being seen for ACS, to help improve future care. You may be invited to join if you can provide informed consent.
Apeldoorn, GelderlandAges 18 years+ - NCT02762162Recruiting
Registry of heart artery patients’ platelet test results
This registry collects information from people with coronary (heart) artery disease who already had platelet-related blood tests as part of usual care. The goal is to better understand how platelet responses relate to treatment and outcomes, which may help future care.
ParisAges 18 years+ - NCT03836521Recruiting
Registry for valve replacement in bicuspid aortic stenosis patients
This registry collects information about adults with severe narrowing of the aortic valve caused by a bicuspid (two-leaflet) valve shape, especially if symptoms are present. It may help doctors better understand who benefits from a catheter-based valve replacement (TAVR).
Los Angeles, CaliforniaAges 19–129
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,609 recruiting cardiology studies from the U.S. registry right now, out of 14,617 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.