Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,609 recruiting studies in this area right now.
By phase
- Not applicable7,632
- Phase 4472
- Phase 2469
- Phase 3439
- Phase 1350
- Phase 1/Phase 2160
- Phase 2/Phase 387
Top conditions
- Stroke797
- Heart Failure534
- Hypertension388
- Cardiovascular Diseases373
- Coronary Artery Disease363
- Multiple Myeloma327
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction97
- Congenital Heart Disease84
- Peripheral Arterial Disease79
- Stroke, Ischemic78
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital68
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California453
- Alabama196
- Arizona181
- Massachusetts173
- New York168
- Florida140
- Texas122
- Maryland118
- Minnesota117
- Illinois112
Recruiting studies9,609 total
- NCT07318610RecruitingPhase 3
Study of a new blood thinner in people with leg artery disease
This trial tests if a new blood-thinning drug (factor XI inhibitor) can prevent serious heart and leg problems in people who recently had a leg artery procedure. It compares the new drug to standard care for up to 3 years.
Alexander City, AlabamaAges 18 years+ - NCT07643896Recruiting
Blood test for pregnancy risk assessment using fetal cells
This study tests a new blood test that looks for fetal cells in your bloodstream to check your baby's health during pregnancy. The test is non-invasive—just a regular blood draw—and aims to help identify pregnancy risks earlier than traditional methods.
Phoenix, ArizonaAges Any age - NCT07132788Recruiting
Study of pulmonary arterial hypertension and lean muscle mass
This study looks at how pulmonary arterial hypertension (PAH) affects lean muscle mass. It aims to understand the relationship between PAH and muscle loss, which could help improve treatments and quality of life.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07445087Recruiting
Takhzyro for hereditary angioedema in teenagers and adults
This study is for people in South Korea with hereditary angioedema. It looks at how well the drug Takhzyro works and how safe it is for teenagers and adults who are already using it or will start using it.
Suwon, Gyeonggi-doAges 12 years+ - NCT07825064RecruitingPhase 2
Cevostamab combination after CAR T-cell therapy for multiple myeloma
This trial tests a new drug, cevostamab, combined with two standard medicines (pomalidomide and dexamethasone) for people with multiple myeloma who have already had CAR T-cell therapy. It aims to see if this combination can help control the cancer better.
GreifswaldAges 18 years+ - NCT06604650Recruiting
Park-based health program for older adults in Miami
This study looks at how community park programs can help older adults stay healthy. It will use information already collected from people who are already part of the Miami-Dade Active Older Adults study.
Miami, FloridaAges 50–95 - NCT07089576Recruiting
Study of the Arcevo LSA device for aortic arch repair
This trial tests a new device called Arcevo LSA to treat certain types of aortic arch problems, like dissections (tears) or aneurysms (bulges). It is for people who need open surgery, and the device helps fix the left subclavian artery area.
Birmingham, AlabamaAges 18–80 - NCT05030545RecruitingPhase 4
PET/CT study of spironolactone or eplerenone in primary aldosteronism
This study looks at how primary aldosteronism affects the heart and blood vessels, and whether blocking its hormone signal (with spironolactone or eplerenone) changes those findings on imaging tests. It is small and focuses on people with confirmed or suspected primary aldosteronism who are being followed for heart health.
Boston, MassachusettsAges 18–85 - NCT07424833RecruitingPhase 1
Study of APG-3288 for Relapsed/Refractory Blood Cancers
This trial is testing a new drug called APG-3288 for people with certain relapsed or treatment-resistant blood cancers (like CLL/SLL, DLBCL, MCL, WM, MZL, or FL). You may qualify if you've tried at least 2 prior treatments and are looking for a new option.
Los Angeles, CaliforniaAges 18 years+ - NCT02504853Recruiting
Study food allergy patterns and genetics over time
This study follows people with food allergy and some closely related or healthy people to learn how food allergy (and related conditions) develops over time. It may help researchers find causes and better ways to predict and treat food allergy.
Bethesda, MarylandAges 1 day–99 years - NCT07200089RecruitingPhase 1
IL-7 treatment after CAR-T therapy for multiple myeloma
This trial tests whether a drug called NT-I7 (a lab-made immune booster) can help people with multiple myeloma who have already received a CAR-T cell therapy called cilta-cel. It's for patients whose myeloma has come back or hasn't responded well to treatment.
St Louis, MissouriAges 18 years+ - NCT07876336Enrolling by invitation
Gene testing for heart patients on clopidogrel in Egypt
This study looks at how well your body processes clopidogrel (a blood thinner), based on your genes. It aims to see if certain gene changes affect how the medicine works for Egyptian patients after heart procedures.
GizaAges 18–70 - NCT07749170Recruiting
Stroke treatment for blockages in smaller brain arteries
This study looks at how well a special catheter system works to remove blood clots from smaller arteries in the brain after a stroke. It aims to see if this treatment helps people recover better.
Englewood, ColoradoAges 18 years+ - NCT07181109RecruitingPhase 3
Study of zilebesiran for high-risk hypertension patients
This trial tests a new medicine called zilebesiran for people with high blood pressure that isn't well controlled. It may be an option if you have heart or blood vessel disease, or are at high risk for it.
Birmingham, AlabamaAges 18 years+ - NCT02797366RecruitingPhase 2
Proton beam radiation for adult brain and spine tumors
This trial studies whether proton radiotherapy can treat primary brain (and sometimes spine) tumors in adults. You may join because your tumor type and situation fit specific diagnoses, including some cases needing a re-treatment plan.
GothenburgAges 18 years+ - NCT03065413Recruiting
Study of heart health, habits, and mood in sailors
This study looks at how common heart and blood vessel problems are, and how changes in activity, diet, and anxiety or depression show up over time in naval personnel. It may help improve understanding of risk factors and mental well-being in this group.
Athens, AthensAges 18 years+ - NCT01889459Recruiting
Registry after stent procedure for blocked heart arteries
This study follows people who had a stent placed for a long-standing blockage in a heart artery (called a CTO). It’s mainly a “registry” to understand outcomes after these procedures and help improve care in the future.
KurashikiAges 20 years+ - NCT02791152Recruiting
Exercise and blood pressure monitoring in healthy adults
This study looks at how physical activity and regular blood pressure checks relate to heart health signals on imaging. It’s meant for people without major heart, stroke, diabetes, or serious chronic illnesses to understand early cardiovascular risk.
Singapore, SingaporeAges 21–69 - NCT02650453Recruiting
Registry for surgeries to restore blocked deep leg veins
This study keeps a registry (a secure list of patient information) for people who have major blockages in deep veins in the leg or pelvis and need a vein repair procedure. It may help doctors understand outcomes over time and improve future care.
MaastrichtAges Any age - NCT02038517Recruiting
Liver transplant waitlist study for people without diabetes
This study is for people with end-stage cirrhosis who are on the liver transplant waitlist at this hospital. It aims to understand how getting a liver transplant may affect people with and without diabetes-related issues.
Milan, MIAges 18–65 - NCT02804269Recruiting
Ages 16 to 90 for heart disease information collection
This is a repository program that collects health and imaging-related information to better understand heart (cardiovascular) health and disease. You may be able to join if you are in the age range and share your data for research use.
Singapore, SingaporeAges 16–90 - NCT02869555Recruiting
Study of people with multiple myeloma in a patient database
This is a study that collects information from people diagnosed with multiple myeloma. It may help researchers understand the disease and improve future care by using past and ongoing patient data.
Marseille, Bouches-du RhôneAges 18–95 - NCT02998788Recruiting
Heart failure risk monitoring for hospitalized adults
This trial studies how to better assess and manage risk in people hospitalized with heart failure or related serious heart problems. It may help by improving how clinicians monitor your condition over time and decide next steps.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT02381301Recruiting
Blood and heart CT scan tests for heart blood-flow markers
This study looks at whether certain lab “biomarkers” and a heart CT scan can help understand heart blood flow in people getting routine coronary CT angiography (CCTA). It may be useful for improving how doctors assess heart health from scan and blood results.
Maastricht, LimburgAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,609 recruiting cardiology studies from the U.S. registry right now, out of 14,617 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.