Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,981 recruiting studies in this area right now.
By phase
- Not applicable7,957
- Phase 2482
- Phase 4481
- Phase 3449
- Phase 1361
- Phase 1/Phase 2164
- Phase 2/Phase 387
Top conditions
- Stroke841
- Heart Failure566
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke201
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke138
- Myocardial Infarction100
- Pulmonary Hypertension100
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois118
- Texas117
Recruiting studies9,978 total
- NCT07075978Enrolling by invitation
Mobile health study for chronic conditions
This study tests two ways of checking on your health at home: using a special device or having regular phone calls with a nurse. It's designed for people who already take medication for blood pressure or diabetes and have one of several chronic conditions.
Richmond, VirginiaAges 18 years+ - NCT06819436RecruitingPhase 4
Dexamethasone for spinal anesthesia side effects
This trial tests if a steroid called dexamethasone can prevent low blood pressure after spinal anesthesia for orthopedic surgery. If you are having hip, knee, or other bone surgery with spinal anesthesia and are otherwise healthy, this study may help reduce side effects.
Karachi, SindhAges 65–85 - NCT06818500Recruiting
Body composition and blood vessel health in women with a healthy weight
This study looks at how body composition (muscle and fat) affects blood vessel health in women who have a healthy body weight. The goal is to learn more about blood vessel function in this group.
Muncie, IndianaAges 18–50 - NCT05390983Recruiting
Compare surgery vs balloon/stent for re-narrowed neck artery
This trial compares two treatments for a carotid artery that has narrowed again after a prior stent: surgery (endarterectomy) versus repeat balloon treatment with or without stenting. It may help find which approach works better to prevent further narrowing and complications.
Ostrava, Moravian-Silesian RegionAges 18–80 - NCT06814951Recruiting
Breathing & movement technique after heart bypass surgery
This study tests a special breathing and movement technique called the Thoraco-abdominal Rebalance Method to see if it helps people recover faster after heart bypass surgery.
Porto Alegre, Rio Grande do SulAges 35 years+ - NCT07027683Enrolling by invitation
Heart MRI to detect hidden rupture after heart attack
This trial uses a special heart MRI to find and guide treatment for a hidden tear in the heart wall that can happen after a heart attack. It is for people who have had a STEMI and then developed early inflammation of the heart lining.
PisaAges Any age - NCT06811194Enrolling by invitation
ECG to detect past heart attacks
This trial uses an electrocardiogram (ECG) to find people who have had a past heart attack or are at high risk for coronary artery disease. It may help understand how ECG patterns relate to heart health.
Chengdu, SichuanAges 35–85 - NCT06650488RecruitingPhase 4
Clopidogrel vs. Aspirin for Heart Protection in Blood Infection Patients
This trial tests whether switching from aspirin to clopidogrel better protects your heart and blood vessels during recovery from a serious staph infection in the blood. You may be eligible if you currently take aspirin for heart or stroke prevention.
Montreal, QuebecAges 18 years+ - NCT06806670Recruiting
Diet and exercise study for kidney transplant patients
This study tests whether a structured diet and exercise program can lower heart disease risk in kidney transplant recipients. If you've had a stable transplant for at least 6 months and up to 10 years, you may be able to join.
Bologna, BOAges 30–69 - NCT06804980RecruitingPhase 4
Rosuvastatin Tolerance for People with Statin Side Effects
This trial tests a low dose of rosuvastatin (a common statin) in people who have had trouble with statins before. The goal is to see if your body can tolerate this specific dose again, which could help lower your cholesterol without the past side effects.
Minneapolis, MinnesotaAges 21 years+ - NCT06784557RecruitingPhase 4
Study of ezetimibe's effect on gut bacteria
This trial tests whether ezetimibe, a cholesterol-lowering drug, changes the bacteria in your gut. It may help people with heart disease or high cholesterol who are already on a statin.
SeoulAges 19–80 - NCT05758701RecruitingPhase 4
CT scan study for people getting TAVR
This trial studies your abdomen using a CT scan around the time you receive TAVR (a heart valve procedure). The goal is to understand how the abdomen area looks on CT and what that might mean for care.
Baltimore, MarylandAges 18–88 - NCT06118281RecruitingPhase 3
Testing ziltivekimab after a heart attack
This study tests a new drug called ziltivekimab to see if it helps people who have recently had a heart attack. The drug is given as an injection and compared to a placebo (a shot with no active medicine).
Alexander City, AlabamaAges 18 years+ - NCT07438613Recruiting
Ultrasound of neck vein for fluid levels in dialysis
This trial uses ultrasound to check the fluid levels in people on long-term dialysis. It aims to see if this can help doctors better adjust their treatment.
BolognaAges 18 years+ - NCT07453940Enrolling by invitation
Closing off heart pouch with or without pulsed energy in atrial fibrillation
This study tests if adding a special energy treatment (pulsed field ablation) to a standard heart pouch closure is safe and works better for people with persistent atrial fibrillation who have few symptoms but a high risk of stroke.
Hangzhou, ZhejiangAges 18 years+ - NCT06731257Recruiting
Early discharge after a heart attack with home monitoring
This trial tests if people with a mild heart attack can go home early (within 48 hours) and be monitored virtually instead of staying in the hospital. It aims to make recovery more comfortable while ensuring safety.
LeedsAges 18–99 - NCT06735976Recruiting
Safety and effectiveness of LOBO device for PAVM treatment
This study tests a new device (LOBO™) to block abnormal blood vessels in the lungs called PAVMs. It is for people with HHT or similar conditions, and the device is placed into the vessel to reduce the risk of stroke or bleeding. You may be able to join if you have a suitable PAVM that is large enough and you are not taking blood thinners.
Chapel Hill, North CarolinaAges 14 years+ - NCT06655389Recruiting
Link between PLA levels and sepsis heart failure severity
This study looks at how levels of a substance called PLA relate to how severe sepsis-related heart failure is. It may help doctors understand your condition better and guide treatment.
Beijing, Beijing MunicipalityAges 50–90 - NCT06726811Recruiting
Droperidol and changes in heart electrical activity
This study looks at how a medication called droperidol (given through an IV for nausea or agitation) affects the heart's electrical activity. If you are in the emergency department and need both an ECG and droperidol, researchers will check your heart tracing before and after the medication to see if there are any changes.
Corpus Christi, TexasAges 18 years+ - NCT06721312Recruiting
Heart rate tracking for doctor stress
This study uses a smartphone app to track your heart rate changes over time. It aims to understand how doctors' stress and recovery patterns relate to their well-being, resilience, and burnout.
AberdeenAges Any age - NCT06719518Recruiting
Testing a noninvasive blood pressure monitor during surgery
This study tests a new device that measures blood pressure continuously without needing a needle in your artery. If you are having surgery and already need an arterial line, this device might offer a less invasive way to track your blood pressure during the procedure.
Houston, TexasAges 18 years+ - NCT06713096Recruiting
Recovery plan for faster healing after bypass surgery
This trial tests a structured recovery plan to help people leave the hospital sooner after coronary artery bypass surgery. It may be a good fit if you are having planned or urgent bypass surgery and do not have severe heart or kidney problems.
São Paulo, São PauloAges Any age - NCT05918211RecruitingPhase 3
Udenafil test during exercise for teens with Fontan circulation
This trial tests whether udenafil helps teens and young people with Fontan circulation do better on exercise and breathing-related measures over time. You’d need to be on blood-thinning medicine, and be able to complete exercise testing safely.
Phoenix, ArizonaAges 12–18 - NCT06706791RecruitingPhase 4
Empagliflozin for heart failure & diabetes: quality of life study
This trial tests whether a diabetes medicine called empagliflozin can improve the quality of life for people who have both chronic heart failure with a weak heart pump and type 2 diabetes. It compares the effects of adding empagliflozin to your current treatments.
Karachi, SindhAges 40–70
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,981 recruiting cardiology studies from the U.S. registry right now, out of 15,236 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Injuries & trauma
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.