Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,610 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3437
- Phase 1350
- Phase 1/Phase 2160
- Phase 2/Phase 387
Top conditions
- Stroke796
- Heart Failure534
- Hypertension389
- Cardiovascular Diseases373
- Coronary Artery Disease363
- Multiple Myeloma327
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease84
- Peripheral Arterial Disease80
- Stroke, Ischemic78
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital68
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California451
- Alabama195
- Arizona181
- Massachusetts173
- New York168
- Florida140
- Texas122
- Maryland118
- Minnesota117
- Illinois111
Recruiting studies9,610 total
- NCT07672249Recruiting
Study on iliac stenting to prevent major leg events
This study looks at people with narrowed or blocked arteries in the pelvis (iliac arteries) who receive a stent to improve blood flow. It aims to understand which factors might predict future serious problems in the legs, like worsening pain or amputation.
Milan, MiAges 18 years+ - NCT07679009Enrolling by invitation
Cardiac MRI for people with pacemakers or ICDs
This trial uses cardiac MRI to check the heart in people who have older or damaged pacemaker leads or who have permanent leads on the outside of the heart. The goal is to see if MRI can safely provide useful images without causing problems.
Dallas, TexasAges 18 years+ - NCT07677319Recruiting
Heart surgery after age 75: a study on recovery
This study looks at how well people aged 75 and older recover after emergency heart surgery. It uses a special test to measure frailty and quality of life for one year after surgery.
Bordeaux, FranceAges 75 years+ - NCT07679828Recruiting
Polypill for multiple heart and diabetes risk factors
This study tests a single daily pill combining several medicines to lower blood pressure and cholesterol in people with type 2 diabetes. Taking one pill may be easier than taking multiple medicines, which could help you stay healthy.
Zhengzhou, HenanAges 50–75 - NCT07672795Recruiting
Clot removal treatment for severe stroke in the back of the brain
This study tests whether a minimally invasive procedure to remove a large blood clot from the main artery at the back of the brain can help people who have had a severe stroke. It aims to improve recovery and reduce disability.
Hefei, AnhuiAges 18–85 - NCT07673536Recruiting
Heart transplant monitoring with extracellular vesicles
This study uses tiny particles called extracellular vesicles (which cells release) to check for signs of organ rejection after a heart transplant, aiming for a safer and less invasive alternative to biopsies.
Berlin, State of BerlinAges 18 years+ - NCT07673562Recruiting
A simple test to detect heart failure early in adults over 55
This study tests a simple questionnaire and heart test to find hidden heart failure in people over 55. It aims to catch the condition early so treatment can start sooner.
Saint-Denis, ReunionAges 55 years+ - NCT07680270Enrolling by invitation
Measuring quality of life after heart procedures
This study measures how heart procedures affect quality of life for both patients and their caregivers, using simple questionnaires.
Clermont-FerrandAges Any age - NCT07678697Recruiting
Laser and injection treatment for spider and reticular veins
This trial compares two types of laser treatments combined with injection therapy for small leg veins (spider veins and reticular veins). It aims to find which approach works better for cosmetic improvement.
CairoAges 18–60 - NCT07674329Recruiting
Virtual reality rehab for arm strength after stroke
This trial tests if using virtual reality (VR) exercises early after an ischemic stroke can help improve arm muscle strength, thinking skills, and mood. It is for people who have had a stroke within the last 10 days.
TaipeiAges 18–85 - NCT07674758Recruiting
Understanding heart risk in Duchenne and Becker muscular dystrophy
This study looks at heart health in people with Duchenne or Becker muscular dystrophy to find better ways to predict and track heart problems. The goal is to improve future treatment trials.
Sacramento, CaliforniaAges Any age - NCT07674498Recruiting
Immune health in older adults with advanced myeloma
This trial studies the immune system of adults 65 and older with multiple myeloma that has come back or not responded to treatment. It looks at how their immune fitness may affect their ability to receive newer therapies like CAR-T cells or bispecific antibodies.
Anderlecht, Brussels CapitalAges 65 years+ - NCT07674004Recruiting
Testing a new flow diverter for brain aneurysms
This trial tests a special metal mesh tube, called a flow diverter, to treat unruptured brain aneurysms. The goal is to see how safe and effective it is for preventing strokes.
Zhengzhou, HenanAges 18–75 - NCT07679555Recruiting
Hemoadsorption therapy outcomes study
This trial looks at how a blood-filtering treatment called hemoadsorption affects patients' health and lab results. It may help people who are already receiving this therapy.
Kistarcsa, Pest CountyAges 18 years+ - NCT07674680RecruitingEarly Phase 1
Heart function study in women of different ages and body sizes
This trial tests how a drug affects heart function in women who have either a low or high body mass index (BMI). It aims to understand cardiovascular health differences across ages and body sizes.
Columbia, MissouriAges 18–70 - NCT06311708Recruiting
PKP2-related heart condition natural history study
This study looks at how plakophilin 2 (PKP2)-related arrhythmogenic right ventricular cardiomyopathy (ARVC) progresses over time. You'll give blood samples to check for antibodies to a virus used in gene therapy, and help doctors understand the disease better.
San Francisco, CaliforniaAges 14–65 - NCT06125392Recruiting
New Definition for Small Heart Vessel Disease
This trial studies a condition where small heart vessels don't work well. It looks at new ways to define this problem using a special test that measures pressure and blood flow in a heart artery.
Mainz, Rhineland-PalatinateAges 18–90 - NCT06669962Recruiting
Studying heart function in Takotsubo syndrome
This trial aims to understand the chemical and physical changes in the heart's blood vessels during Takotsubo syndrome, a temporary heart condition often triggered by stress. It may help doctors better diagnose and treat this condition.
Turin, TurinAges 18–90 - NCT06669520Recruiting
Renalase and blood vessel blockages after heart attack
This study is looking at a protein in the blood (renalase) and how it relates to blockages in tiny blood vessels after a heart attack. Researchers want to see if this protein can help predict recovery, which could lead to better treatments.
Changsha, HunanAges 18 years+ - NCT06670456Recruiting
Brain Bleed Study (Without Surgery)
This study is for people who had a spontaneous brain bleed and did not have surgery. It aims to learn more about their recovery and health over time.
Fuzhou, FujianAges 18 years+ - NCT06570902Recruiting
Heart monitor vest after first bypass surgery
This study tests a wearable heart monitor vest (WCD) for people who have had their first coronary bypass surgery and have a weakened heart pump (ejection fraction below 35%). The vest watches for dangerous heart rhythms and can shock the heart back to normal if needed.
Bad Nauheim, HesseAges 18 years+ - NCT06567106Recruiting
Heart function study with gentle ultrasound
This trial uses low-intensity ultrasound to see if it can safely measure or affect heart function in healthy people. It aims to understand how the heart works during a simple, non-invasive procedure.
ShanghaiAges 18–65 - NCT06673381Recruiting
Blood markers for inflammation in heart attack
This study is checking if a simple blood test (hs-CRP to albumin ratio) can help predict outcomes in people who have had a heart attack or unstable angina but are not getting an immediate balloon/stent procedure. It aims to use inflammation markers to guide better care.
SohagAges 18 years+ - NCT06673615Recruiting
Early stages of heart failure study
This study follows people in the early stages of heart failure to understand how the condition develops. It may help researchers find better ways to detect and treat it sooner.
Shanghai, Shanghai MunicipalityAges 60 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,610 recruiting cardiology studies from the U.S. registry right now, out of 14,650 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Pain
- Injuries & trauma
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.