Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,981 recruiting studies in this area right now.
By phase
- Not applicable7,957
- Phase 2482
- Phase 4481
- Phase 3449
- Phase 1361
- Phase 1/Phase 2164
- Phase 2/Phase 387
Top conditions
- Stroke841
- Heart Failure566
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke201
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke138
- Myocardial Infarction100
- Pulmonary Hypertension100
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois118
- Texas117
Recruiting studies9,978 total
- NCT05759806Recruiting
Testing a device to treat fluid overload in heart failure
This trial studies a device (the Nephronyx System) used in the hospital to treat worsening heart failure with fluid buildup, especially when diuretics (water pills) aren’t working well. It aims to check the device’s safety and whether it performs as expected to help patients get better.
HaifaAges 18 years+ - NCT05922202Recruiting
Studying how frailty affects outcomes in COPD
This study looks at whether frailty (how weak or vulnerable someone is) changes the risk of heart-related events and death in people with COPD. It may help doctors better predict who is at higher risk and tailor care.
ModenaAges 40 years+ - NCT07727681RecruitingPhase 4
Statins to Prevent Atrial Fibrillation After Lung Surgery
This trial tests whether taking a statin before and after lung surgery can prevent a common heart rhythm problem called atrial fibrillation (AFib). If you are 60 or older and having a lung segment or lobe removed, this study may help you avoid AFib after your operation.
BeijingAges 60 years+ - NCT06700018Recruiting
Blood Flow Patterns and Stent Clots
This study looks at how blood flow patterns inside a heart stent may lead to dangerous clots. If you had a stent placed with a special camera (OCT) and later developed a clot in that stent, this trial may help understand why.
LondonAges Any age - NCT07269717RecruitingPhase 2
Testing HRS-1893 for heart failure with preserved ejection fraction
This trial tests a new drug called HRS-1893 for people with heart failure with preserved ejection fraction (HFpEF). It aims to see if the drug can improve symptoms and quality of life.
Shanghai, Shanghai MunicipalityAges 40 years+ - NCT06695429Recruiting
Beetroot juice to prevent kidney damage from contrast dye
This trial tests if drinking beetroot juice can help protect your kidneys from damage caused by the dye used during heart procedures. It is for people hospitalized with a certain type of heart attack who are at moderate to high risk of kidney problems.
CartagenaAges 18 years+ - NCT05951088Recruiting
Mobile app follow-up for heart patients with AF or heart failure
This study tests a smartphone or tablet app that helps keep track of follow-up care for people with certain heart rhythm problems (AF/atrial flutter) and/or heart failure. If you join, you would be followed long-term to see whether the app can support ongoing care.
Edegem, AntwerpAges 18 years+ - NCT07613853Recruiting
Sharing heart disease risk information with patients
This study tests whether giving patients information about their heart disease risk through simple digital links helps them understand and act on their health. You're invited if you attended a recent Dallas Heart Study visit.
Dallas, TexasAges 35 years+ - NCT06687863Enrolling by invitation
Exercise and genes in high blood pressure with sleep apnea
This study looks at how exercise and your genes affect blood pressure in people with both high blood pressure and obstructive sleep apnea (a condition where breathing stops briefly during sleep). It aims to see if a tailored exercise program can help you better control your blood pressure.
São Paulo, São PauloAges 45–70 - NCT06686862RecruitingPhase 3
Anti-inflammatory drugs for acute myocarditis
This trial tests if non-steroidal anti-inflammatory drugs (NSAIDs), like ibuprofen, help people with acute myocarditis (inflammation of the heart muscle) who are hospitalized but have normal heart function. It aims to see if these drugs can reduce inflammation and improve recovery.
Majadahonda, MadridAges 18 years+ - NCT06679855RecruitingPhase 3
Milrinone to prevent heart problems after PDA closure
This trial tests if giving milrinone before surgery to close a common heart vessel (PDA) can prevent heart issues in premature babies. It may help very premature infants who need surgery for a large PDA.
Birmingham, AlabamaAges Up to 3 months - NCT07349186Recruiting
Blood pressure monitoring during robot prostate surgery
This trial compares two ways to measure blood pressure during robot-assisted prostate surgery: a cuff on the arm (oscillometric) vs. a tiny tube in an artery (intraarterial). It aims to see if the cuff method is just as reliable, which could make monitoring simpler and less invasive.
Hamburg, Free and Hanseatic City of HamburgAges 18 years+ - NCT06673953Recruiting
Breathing training for heart surgery recovery with neck posture problems
This trial tests whether a breathing exercise device can improve heart and lung function in men who had heart bypass surgery at least 3 months ago and also have neck pain from poor posture. It may help you breathe better and feel stronger after surgery.
Giza, Giza GovernorateAges 45–55 - NCT06670001Recruiting
Increasing daily steps in heart failure with preserved ejection fraction
This study tests if simple rewards and reminders on a smartphone can help people with a certain type of heart failure (HFpEF) become more physically active. The goal is to see if increasing daily steps improves their health and well-being.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05937841RecruitingEarly Phase 1
Test how a blood-pressure hormone receptor works after preeclampsia
This early study looks at how “angiotensin II” receptors behave in women after preeclampsia compared with women who didn’t have it. It may help researchers understand long-term health risks after pregnancy and guide future treatments.
Iowa City, IowaAges 18–45 - NCT06528977Recruiting
Western diet's effect on heart and immune health
This study looks at how a typical Western diet affects heart health and immune function in healthy middle-aged adults. You will follow a carefully controlled diet for several weeks, and researchers will measure changes in your blood pressure, cholesterol, and immune markers.
Newark, DelawareAges 50–64 - NCT06411392Recruiting
Radiation therapy for difficult-to-control fast heart rhythm
This study tests a form of focused radiation (SBRT) to treat a dangerous fast heart rhythm called ventricular tachycardia (VT) when medicines and other procedures haven't worked. It may help reduce the number of VT episodes and improve your quality of life.
GrazAges 18 years+ - NCT06583785Recruiting
Black rice and brain health in older adults
This study tests whether eating black rice can help with memory, thinking, and overall health in older adults. The researchers want to see if black rice reduces inflammation and improves blood vessel function, which can benefit the brain and body.
Reading, UKAges 50–80 - NCT07433998Recruiting
Ginger drink for inflammation and blood vessel health
This study tests whether a ginger-based drink can reduce inflammation and oxidative stress (a type of cell damage) and improve blood vessel health. It may help adults who are overweight but otherwise healthy.
MurciaAges 23–65 - NCT07361445Recruiting
Study of a device to help access the heart during ablation
This trial tests a new device to help doctors safely enter the left side of your heart during a procedure called ablation. If you are already scheduled for an ablation or a combined ablation and left atrial appendage closure, this study may be an option.
Jonesboro, ArkansasAges 18 years+ - NCT07362719Recruiting
Thermal cure for severe leg vein problems
This study tests if a 3-week thermal spa treatment can improve symptoms of severe chronic venous insufficiency (vein problems in your legs that cause swelling, skin changes, and risk of leg ulcers). It may help if you have serious vein issues but no open ulcers.
AmnévilleAges 18 years+ - NCT06942221Recruiting
Digital Heart Failure Support After Hospital Stay
This trial tests a digital health tool to help manage heart failure medications after you leave the hospital. If you were recently hospitalized for heart failure and have a smartphone or tablet, you may be able to join.
BaselAges 18 years+ - NCT06692933RecruitingEarly Phase 1
How hemp affects a common blood thinner
This study tests if a hemp product changes how the body processes the blood thinner clopidogrel (Plavix). You must be healthy, have used cannabis before without problems, and have a specific gene type that affects how these substances break down.
Spokane, WashingtonAges 21–64 - NCT06619444Recruiting
Resistance exercise and heart health in overweight adults
This study looks at how different amounts of resistance training (like lifting weights) affect heart health in people who are overweight and don't exercise much. It may help find the best exercise dose to improve cardiovascular health.
Pittsburgh, PennsylvaniaAges 40 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,981 recruiting cardiology studies from the U.S. registry right now, out of 15,236 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.