Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,981 recruiting studies in this area right now.
By phase
- Not applicable7,957
- Phase 2482
- Phase 4481
- Phase 3449
- Phase 1361
- Phase 1/Phase 2164
- Phase 2/Phase 387
Top conditions
- Stroke841
- Heart Failure566
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke201
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke138
- Myocardial Infarction100
- Pulmonary Hypertension100
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois118
- Texas117
Recruiting studies9,978 total
- NCT05858944Recruiting
Home blood pressure program for people with high readings
This trial tests whether a home blood pressure–focused program helps improve blood pressure control in older adults. You may be asked to measure your blood pressure at home for at least several days and attend follow-up visits.
Shanghai, Shanghai MunicipalityAges 60–80 - NCT06774365Recruiting
Heart imaging and blood tests for transplant rejection detection
This study uses advanced heart imaging and blood tests to detect a type of rejection that can happen after a heart transplant. It may help doctors diagnose antibody-mediated rejection earlier and more accurately.
Bari, BariAges 18 years+ - NCT06900972Enrolling by invitationPhase 3
Comparing fluids' effect on heart function
This trial compares two types of IV fluids (colloids and crystalloids) to see how they affect heart function. It is open to healthy adults who are not pregnant and have no known medical problems.
Monastir, TunisiaAges 18–60 - NCT06900257Enrolling by invitation
Fetal heart function in fasting pregnant women
This study looks at how babies' hearts work when mothers have been fasting for at least 10 days. It may help understand if fasting affects the baby's heart health.
SanliurfaAges 18–50 - NCT06790472Enrolling by invitation
Metabolic wellness and continuous glucose monitor study
This study looks at how wearing a continuous glucose monitor (CGM) can help employees of Sutter Health understand their metabolic wellness. You will wear a small sensor on your arm that tracks your blood sugar levels over time.
Palo Alto, CaliforniaAges 18 years+ - NCT06700681Enrolling by invitation
Comparing two sedatives for heart ablation procedures
This trial compares two sedative medicines (remimazolam and propofol) given during heart ablation procedures. The study uses brain-wave monitoring to see which medicine provides better sedation and recovery. It's for people who are already scheduled for this procedure with a specific doctor.
TaipeiAges 20–80 - NCT06899867Recruiting
Comparing heart monitoring methods during liver transplant
This trial compares two ways to monitor how well your heart is pumping during liver transplant surgery. One method uses a thin tube in your blood vessels, and the other uses an ultrasound probe placed in your food pipe.
France, LyonAges 18 years+ - NCT06898762Recruiting
National study on inflammatory heart disease for patients with symptoms
This study is creating a national registry to learn more about inflammatory myocardial disease (inflammation of the heart muscle). If you have symptoms like chest pain, shortness of breath, palpitations, or certain test results, you may be eligible to join and help advance research.
Murcia, MurciaAges 18 years+ - NCT06724718Recruiting
Using a smartwatch to detect atrial fibrillation after chest surgery
This trial tests whether a smartwatch can detect atrial fibrillation in people who have had major chest surgery (like lung removal) within the last 48 hours. If successful, this could help catch heart rhythm problems early without extra hospital equipment.
AmiensAges 18 years+ - NCT05862103Recruiting
Long-term follow-up for people after a heart attack
This trial is a long-term check-in for people who survived a heart attack and already took part in an earlier study through a 1-year follow-up. The goal is to learn what happens over time after the heart attack and how participants are doing.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06898151Recruiting
Comparing timing of carotid surgery or stenting after stroke
This trial compares the best timing for surgery or stenting to open a narrowed carotid artery after a minor stroke. The goal is to see if doing the procedure sooner or later reduces the chance of another stroke.
BeijingAges 18 years+ - NCT06872762Recruiting
Exercise and heat stress in healthy young adults
This study tests how exercise in a hot environment affects your heart and metabolism. It may help researchers understand how heat and exercise work together in healthy, active young adults.
Flagstaff, ArizonaAges 18–50 - NCT06895603Recruiting
New cuff to measure blood flow during heart procedures
This trial tests a new upper-arm cuff that may measure your heart's blood flow without needing an extra tube in your heart. If you already need a special heart catheter and a wrist arterial line, this study will see if the cuff works just as well.
Charlottesville, VirginiaAges 18 years+ - NCT06896903Recruiting
Testing heart artery function with and without nitroglycerin
This study compares two ways of testing the small blood vessels in the heart to understand chest pain when no major blockages are found. It may help doctors learn more about why you have chest pain and how to treat it.
Plano, TexasAges 18 years+ - NCT06682221Enrolling by invitationPhase 3
Resistance training and supplement study for older adults
This study tests whether a resistance training program (like lifting weights) combined with a supplement can improve heart, lung, and metabolic health in older adults. The goal is to find ways to help seniors stay healthier and more active.
Anápolis, GoiásAges 60–85 - NCT05116176Enrolling by invitation
Study of experiences after getting an ICD for heart protection
This study follows people who are scheduled to get a new ICD (a device that helps protect the heart) and asks about their experiences and quality of life. It may help doctors understand what patients feel and how people do after ICD implantation.
Boston, MassachusettsAges 65 years+ - NCT07572435Recruiting
Remote Heart Exercise Program for Kids With Heart Surgery
This study tests whether kids aged 8–18 who had complex heart surgery can safely improve their fitness and well-being using exercise activities at home through a mobile app or video. The goal is to help them become more active after surgery.
SeoulAges 8–18 - NCT03893734RecruitingPhase 4
Methadone vs hydromorphone to check heart rhythm after surgery
This trial tests whether the pain medicines methadone and hydromorphone affect the heart’s electrical timing after general anesthesia and surgery. It may help doctors choose the safer option for patients who need strong pain control after an operation.
Evanston, IllinoisAges 18–80 - NCT06654284Enrolling by invitation
Quality of life after ICD implant or battery change
This study looks at how people feel and live their daily lives after getting an ICD or having the battery changed. Researchers want to understand your quality of life over time.
LeuvenAges 18 years+ - NCT03047161Recruiting
Fetal heartbeat monitoring in pregnancy
This study looks at how to measure and understand an unborn baby’s heart rhythm using special ultrasound/electrical testing. It may help doctors better evaluate abnormal or possibly abnormal fetal heart rates.
Madison, WisconsinAges 18 years+ - NCT07267013RecruitingPhase 2
Testing clindamycin instead of vancomycin in aortic heart surgery
This study tests if clindamycin, a common antibiotic, works as well as vancomycin to prevent infections during heart surgery on the aorta (the main artery from the heart). Patients must be having planned morning surgery with the heart-lung machine and understand French.
Nantes, FranceAges 18 years+ - NCT07033273Recruiting
Ultrasound vein test to predict low blood pressure during dialysis
This study uses an ultrasound to check how much your main vein (inferior vena cava) collapses during dialysis. It aims to see if this measurement can help predict drops in blood pressure during treatment, so doctors can better manage your dialysis sessions.
Wuhu, AnhuiAges 18–80 - NCT05888662Recruiting
Compare two catheter approaches to treat ventricular tachycardia
This study compares an “outer heart” catheter approach (epicardial) versus an “inner heart” approach (endocardial-only) to treat a dangerous heart rhythm called ventricular tachycardia. It aims to see which approach works better and is safest for people with ischemic heart disease who are having their first ablation.
BordeauxAges 18 years+ - NCT06641830Enrolling by invitation
Study of cardiomyopathy in children
This trial studies children with cardiomyopathy to better understand the condition. It's for children who have been diagnosed with cardiomyopathy and who do not have other major heart problems or serious issues with other organs.
Chengdu, SichuanAges Up to 18 years
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,981 recruiting cardiology studies from the U.S. registry right now, out of 15,236 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.