Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,610 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3437
- Phase 1350
- Phase 1/Phase 2160
- Phase 2/Phase 387
Top conditions
- Stroke796
- Heart Failure534
- Hypertension389
- Cardiovascular Diseases373
- Coronary Artery Disease363
- Multiple Myeloma327
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease84
- Peripheral Arterial Disease80
- Stroke, Ischemic78
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital68
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California451
- Alabama195
- Arizona181
- Massachusetts173
- New York168
- Florida140
- Texas122
- Maryland118
- Minnesota117
- Illinois111
Recruiting studies9,610 total
- NCT07681102Enrolling by invitation
Brain stimulation for arm recovery after stroke
This study tests a new type of brain stimulation to help people who have had a stroke and still have limited arm movement. The goal is to see if a specific pattern of stimulation can improve recovery more than others.
Berkeley, CaliforniaAges 18–80 - NCT06342492Recruiting
Comparing two pacing methods for lead failure in heart failure
This study compares two ways to fix a failed lead in a heart failure pacemaker: placing a new lead on the outside of the heart or using the heart's own electrical system. It follows people whose CRT lead stopped working and was replaced, to see which method works best.
Overland Park, KansasAges 18 years+ - NCT06662084Recruiting
Liver enzyme function in people with cardiogenic shock on heart pumps
This study tests whether your liver’s drug-processing enzymes (CYP) work normally during cardiogenic shock when you are on a heart pump like ECMO or Impella®. The goal is to help doctors choose the right medicines for you.
GenevaAges 18 years+ - NCT06075602Recruiting
Complex and calcified coronary artery disease: a registry study
This study watches how people with complex or calcified heart artery disease are treated (with stents or bypass surgery) and how they do over time. It aims to learn which treatments work best for tough blockages.
Lucerne, Canton of LucerneAges 18 years+ - NCT06078735Recruiting
Device vs manual pressure for closing blood vessels after AFib procedure
This study compares two ways to close the vein entry after heart ablation for AFib: the LockeT device versus manual compression. It helps find which method works better.
Overland Park, KansasAges 18 years+ - NCT06621121Recruiting
Comparing two clot-busting drugs for stroke within 4.5 hours
This study compares two medications, tenecteplase and alteplase, to see which works better at dissolving blood clots in people having an ischemic stroke. You may join if you can get treatment within 4.5 hours of when your symptoms started.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT04988685Recruiting
Heart artery balloon treatment registry study for adults
This study follows adults with blocked heart arteries who are treated using a special type of balloon (drug-coated balloon) during a procedure. It aims to track real-world outcomes to better understand how well this treatment works for people with new blockages or previously treated vessel narrowing.
Lucerne, Canton of LucerneAges 18 years+ - NCT06601270Recruiting
SCAD registry: tracking spontaneous coronary artery dissection
This study collects information from people diagnosed with spontaneous coronary artery dissection (SCAD) in the last 10 years. It aims to learn more about this rare heart condition to improve future care.
Buenos AiresAges 18 years+ - NCT06442267RecruitingPhase 4
Comparing blood thinners for ECMO support
This trial compares three different blood thinners (heparin, argatroban, and enoxaparin) used during ECMO support. It aims to find the safest and most effective way to prevent blood clots while on ECMO.
Vienna, State of ViennaAges 18 years+ - NCT06653946RecruitingPhase 4
Predicting bleeding after stroke treatment in patients with atrial fibrillation
This trial looks at why some patients with a first-time stroke caused by atrial fibrillation experience bleeding in the brain after receiving clot-busting medication. It aims to find factors that predict this bleeding, which could help doctors choose safer treatments in the future.
Kafr ash ShaykhAges 18–75 - NCT06663267Recruiting
Weather and air pollution effects on heart health
This trial looks at how weather and air pollution may impact your heart health. It uses medical records to study these effects.
Hanzhou, ZhejiangAges 18–75 - NCT02114450Recruiting
Training with a leg exoskeleton after stroke
This trial tests a “human–machine” leg exoskeleton system to help people with stroke improve standing and walking during rehab. You may be able to participate if you have certain levels of disability and spasticity, can safely stand and walk with help, and don’t have skin, joint, or medical issues that would make training unsafe.
Houston, TexasAges 18–75 - NCT05326828Recruiting
Implant monitor to find hidden atrial fibrillation after heart injury
This study tests whether an implantable heart rhythm monitor can detect atrial fibrillation (an irregular heartbeat) in people who had a type of heart attack with non-obstructed arteries. The goal is to find a possible reason for the event so doctors can treat it appropriately.
BernAges 18–85 - NCT06215989Recruiting
Low-dose colchicine for acute coronary syndrome
This trial tests whether a low dose of the anti-inflammatory drug colchicine can help people who have recently had a heart attack or unstable angina. It aims to see if colchicine reduces the risk of future heart problems.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07675395Enrolling by invitation
Heart remodeling after pulsed field ablation for persistent atrial fibrillation
This study looks at how a new type of heart procedure, called pulsed field ablation, affects the heart's structure in people with persistent atrial fibrillation. It may help doctors understand if this treatment improves heart function over time.
TaipeiAges 18 years+ - NCT07674173Recruiting
Registry study of Minos stent-graft for abdominal aortic aneurysm
This study tracks the long-term safety and effectiveness of the Minos stent-graft system in treating abdominal aortic aneurysms. It collects data from patients across Europe and Asia to see how well the device works over five years.
Lanzhou, GansuAges 18 years+ - NCT06610578Recruiting
Screening for brain artery blockage using eye exams
This trial tests if a simple eye exam can help screen for blocked brain arteries. It may help find people at risk earlier without invasive tests.
Beijing, None SelectedAges 18 years+ - NCT06649968Recruiting
Testing a smart glove for hand recovery after stroke
This trial tests a high-tech glove that helps track and improve hand and arm movement after a stroke. It may be an option for people who had a stroke 1 to 6 months ago and have mild to moderate arm weakness.
AcerenzaAges 18 years+ - NCT06667258Recruiting
Earpiece to detect heart rhythm problems
This trial tests if a special earpiece can detect heart rhythm problems like irregular heartbeats. It could help you monitor your heart in a simple way.
London, Non-US/Non-CanadianAges 18 years+ - NCT07672210Recruiting
Pregnancy-related aortic dissection in China
This study is looking at cases of aortic dissection that happen during pregnancy or shortly after childbirth in China. It aims to understand how these events occur and how they can best be managed.
Shanghai, Shanghai MunicipalityAges 16–55 - NCT07672795Recruiting
Clot removal treatment for severe stroke in the back of the brain
This study tests whether a minimally invasive procedure to remove a large blood clot from the main artery at the back of the brain can help people who have had a severe stroke. It aims to improve recovery and reduce disability.
Hefei, AnhuiAges 18–85 - NCT07673562Recruiting
A simple test to detect heart failure early in adults over 55
This study tests a simple questionnaire and heart test to find hidden heart failure in people over 55. It aims to catch the condition early so treatment can start sooner.
Saint-Denis, ReunionAges 55 years+ - NCT07673536Recruiting
Heart transplant monitoring with extracellular vesicles
This study uses tiny particles called extracellular vesicles (which cells release) to check for signs of organ rejection after a heart transplant, aiming for a safer and less invasive alternative to biopsies.
Berlin, State of BerlinAges 18 years+ - NCT07677995Enrolling by invitation
Fatty acids and type 2 diabetes study
This study looks at how free fatty acids affect people with type 2 diabetes or pre-diabetes. You may be able to join if you are overweight, have high blood sugar, and are not on certain diabetes medications.
Coleraine, County LondonderryAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,610 recruiting cardiology studies from the U.S. registry right now, out of 14,650 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Injuries & trauma
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.