Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,609 recruiting studies in this area right now.
By phase
- Not applicable5,335
- Phase 2607
- Phase 1560
- Phase 3418
- Phase 4318
- Phase 1/Phase 2287
- Phase 2/Phase 384
Top conditions
- Obesity619
- Ovarian Cancer336
- Pancreatic Cancer287
- Type 2 Diabetes275
- Diabetes192
- Diabetes Mellitus182
- Diabetes Mellitus, Type 2171
- Hypertension138
- Type 1 Diabetes131
- Metabolic Syndrome126
- Obesity & Overweight125
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer87
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California520
- Maryland180
- Alabama176
- Arizona171
- Florida166
- Texas159
- Massachusetts150
- New York143
- Colorado115
- Pennsylvania112
Recruiting studies7,609 total
- NCT05200260RecruitingPhase 2
Surgery plus maintenance medicines for advanced ovarian cancer
This trial checks whether having surgery to remove as much tumor as possible, followed by ongoing targeted treatment, helps people with advanced ovarian (and related) cancers live longer and/or control cancer better. It specifically uses tumor-testing results to match patients and then continues treatment after surgery.
FoshanAges 18 years+ - NCT06460038RecruitingPhase 2
Medication study for constipation in Parkinson's
This study tests whether a medication called tenapanor can help relieve constipation in people with Parkinson's disease. If you have Parkinson's and have been struggling with constipation for at least 6 months, this trial may offer a new option to improve bowel regularity.
Waterloo, IowaAges 50–89 - NCT06574282Recruiting
Better diagnosis for hypophosphatasia in rheumatology patients
This study aims to find better ways to diagnose hypophosphatasia (HPP) in adults who see a rheumatologist. If your doctor suspects HPP and you have a low ALP blood test, you may be able to help researchers develop a screening tool.
Bonn, North Rhine-WestphaliAges 18 years+ - NCT06681428Recruiting
Amniotic tissue treatment for diabetic foot ulcers
This trial tests whether an amniotic tissue treatment can help heal chronic diabetic foot ulcers that haven't improved with standard care. It focuses on a single ulcer below the ankle that has been present for more than 4 weeks but less than a year.
Fresno, CaliforniaAges 18 years+ - NCT07421713Recruiting
AI and chest x-rays to screen for osteoporosis
This trial tests if an AI software can use a chest x-ray to screen for osteoporosis, compared to the standard DXA bone density scan. It may offer a faster, simpler way to check bone health in people 50 and older.
RotterdamAges 50 years+ - NCT07417124RecruitingPhase 1
Study of SNS851 for people with high liver fat
This study tests a new medicine called SNS851 in healthy volunteers to see if it is safe and tolerable. It may help people with high liver fat, though it is not yet known if it works.
MelbourneAges 18–60 - NCT07421297RecruitingPhase 3
Study of SYH2053 for high cholesterol in Chinese adults
This trial tests a new medication called SYH2053 for people with high cholesterol or mixed high cholesterol and triglycerides. If you have high LDL cholesterol and are not taking strong cholesterol medicines, you may be able to join. The study will see if this drug is safe and works well.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07424547RecruitingPhase 1
Study of SYS6043 for advanced or metastatic solid tumors
This trial tests a new study drug (SYS6043) for people with advanced or metastatic solid tumors that have not responded to or are not candidates for standard therapies. The drug targets a protein called B7-H3 on cancer cells to help stop tumor growth.
Plantation, FloridaAges 18 years+ - NCT06815978Recruiting
Diagnosing obesity-related muscle loss
This study tests a new tool to diagnose muscle loss in people with obesity. It may help doctors better identify and treat this condition.
Rome, RMAges 18 years+ - NCT06816303Recruiting
Diabetes Treatment in Liver Transplant Patients and Candidates
This study looks at people with type 2 diabetes who are either waiting for a liver transplant or have already had one. Researchers want to understand how diabetes treatment affects outcomes before and after transplant.
Bologna, BOAges 18 years+ - NCT04567121Recruiting
Online lifestyle program to lower common health risk factors
This trial tests an internet-based coaching program to help people with lifestyle-related risk factors (like high blood pressure, diabetes risk, smoking, or fatty liver) improve their health. It may help you better manage risk factors that can lead to heart and other long-term diseases.
Beijing, Beijing MunicipalityAges 25 years+ - NCT07423065Recruiting
Continuous glucose monitor for prediabetes and weight loss
This study tests whether wearing a continuous glucose monitor (a small sensor on your skin that tracks your blood sugar) can help people with prediabetes and obesity better control their blood sugar and lose weight. You will be asked to wear the device for several days to see how your glucose levels change throughout the day.
IzolaAges 18–70 - NCT07423247RecruitingPhase 4
Tirzepatide for weight loss in kidney transplant patients
This trial tests if tirzepatide can help people who have had a kidney transplant and are still overweight lose weight. It may be an option if you have had your transplant at least a year ago, your kidney function is stable, and your body mass index is 27 or higher.
TehranAges 18 years+ - NCT07425275Recruiting
Study of a mouth care plan for dry mouth in diabetes
This trial tests a special mouth care plan to help people with diabetes who have dry mouth. The goal is to see if it improves comfort and mouth health.
Peshawar, KPKAges Up to 18 years - NCT07417410Recruiting
Diabetes eye disease risk study
This study looks back at medical records of people with type 2 diabetes to understand how diabetic eye disease (retinopathy) progresses and when treatment is needed. It may help doctors better predict risks and guide future care.
Portugal, Coimbra DistrictAges 35–90 - NCT07416799Recruiting
Home strength training for diabetes and mild memory loss
This study tests whether a home strength-training program using a smartphone app is doable for older adults with type 2 diabetes who also have mild memory problems. You'll do simple exercises at home, and the program may help improve your thinking and glucose control.
Galveston, TexasAges 55–80 - NCT07418008Recruiting
Thinking and memory study for people with liver cirrhosis
This study is creating a new test to measure thinking and memory problems in people with liver cirrhosis. It may help doctors find these problems earlier.
Ambāla, HaryanaAges 18–75 - NCT07420023Recruiting
Nutrition study for weight management and fullness
This study tests a special food product and meal plan to help people feel fuller longer and control appetite. It may help you understand how certain foods affect your body and weight.
CorkAges 18–45 - NCT07425483RecruitingPhase 1
CAR-NK cell therapy for advanced pancreatic cancer
This trial tests a new treatment using immune cells (CAR-NK cells) to fight pancreatic cancer that has spread or come back. It may be an option if standard treatments have stopped working, were not tolerated, or were refused.
ShanghaiAges 18–75 - NCT07424625RecruitingPhase 4
Comparing two medicines for acidosis after heart surgery
This trial compares two medicines, THAM and sodium bicarbonate, to treat metabolic acidosis (too much acid in the blood) after heart surgery that used a heart-lung machine. The goal is to see which medicine works better for patients in this situation.
Rochester, MinnesotaAges 21 years+ - NCT07423637Recruiting
Early automated insulin delivery for new type 1 diabetes
This study tests whether starting an automated insulin delivery (AID) system soon after a type 1 diabetes diagnosis helps improve blood sugar control and reduces future health problems. The AID system combines a pump and continuous glucose monitor to automatically adjust insulin.
EspooAges 7–16 - NCT07419503Enrolling by invitation
Healthy lifestyle program for overweight children
This study evaluates a healthy lifestyle program for children ages 4 to 12 who are overweight. It looks at how well the program works and gathers feedback from children, parents, and program providers.
Rotterdam, South HollandAges 4–12 - NCT07422831Enrolling by invitation
Intermittent glucose sensor use for type 2 diabetes
This trial is testing whether using a continuous glucose monitor (CGM) for different lengths of time helps people with type 2 diabetes understand their blood sugar patterns. You won't need to change your current diabetes medications.
Aurora, ColoradoAges 18 years+ - NCT07423013Recruiting
Teprotumumab treatment for active thyroid eye disease
This trial tests a new version of an antibody treatment (teprotumumab) for people with active thyroid eye disease. It aims to reduce bulging and inflammation of the eyes, and you must have had symptoms for less than 9 months to join.
BeijingAges 18–80
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,609 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,903 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.