Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,627 recruiting studies in this area right now.
By phase
- Not applicable5,353
- Phase 2607
- Phase 1557
- Phase 3419
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 385
Top conditions
- Obesity618
- Ovarian Cancer337
- Pancreatic Cancer287
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2172
- Hypertension138
- Type 1 Diabetes131
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Cardiovascular Diseases105
- Overweight105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland179
- Alabama176
- Arizona170
- Florida166
- Texas158
- Massachusetts151
- New York144
- Colorado115
- Pennsylvania114
Recruiting studies7,627 total
- NCT07230496RecruitingPhase 1
Safety study of an investigational weight-management drug
This study is testing a new investigational drug, either alone or combined with another drug, to see how safe it is and how the body processes it. It is for healthy people who are overweight or obese, and results may help in developing future treatments for weight management.
Sydney, New South WalesAges 18–75 - NCT07239336RecruitingPhase 2
Study of DONQ52 for active celiac disease
This trial tests a new drug called DONQ52 in people with active celiac disease who still have symptoms despite following a gluten-free diet. The goal is to see if DONQ52 can help reduce damage to the small intestine and improve gluten-related symptoms.
Anniston, AlabamaAges 18–75 - NCT07231419RecruitingPhase 3
Study of suzetrigine for diabetic nerve pain
This trial tests an experimental pain drug called suzetrigine for people with diabetic peripheral neuropathy (nerve damage from diabetes that causes pain in the feet and legs). It aims to see if the drug can safely reduce pain over time.
Birmingham, AlabamaAges 18–80 - NCT06366399Recruiting
Timing of resistance exercise for weight management
This study tests if doing resistance exercises (like lifting weights) in the morning or afternoon is better for weight management. You may qualify if you are between 50 and 74 years old, are overweight but generally healthy, and have not been very active with strength training.
Salt Lake City, UtahAges 50–74 - NCT06473480Recruiting
Continuous glucose sensor vs. fingerstick in hospital patients
This study compares a continuous glucose monitor (a small sensor on the skin) with the usual fingerstick method for checking blood sugar in hospitalized patients. It aims to see if the sensor is more convenient and just as accurate.
Køge, KøgeAges 18–110 - NCT06563401Recruiting
Heart health in adults with type 1 diabetes
This study looks at the long-term risk of heart disease and death in people diagnosed with type 1 diabetes as adults. Researchers will compare their health to people without diabetes to understand how type 1 diabetes affects the heart over time.
StockholmAges 18–110 - NCT06863701RecruitingPhase 3
Combination therapy for acute gout flare
This trial tests a combination of two medicines, etoricoxib and betamethasone, for quickly treating a painful gout flare. It is for people who have had gout before and whose current attack started within two days.
Mexico CityAges 18 years+ - NCT06755840Recruiting
Sleep breathing problems and multiple health conditions study
This study is for people who may have sleep-related breathing problems (like sleep apnea). It looks at how these issues connect with other health conditions. Participants will do a one-night sleep test and some simple health checks at Xiangya Hospital.
ChangshaAges Any age - NCT07231822Recruiting
Virtual reality for postmenopausal osteoporosis patients
This study tests if virtual reality exercises can help improve balance and strength in postmenopausal women with osteoporosis. It may offer a safe and engaging way to support bone and muscle health.
Center, Kirşehi̇rAges 40–65 - NCT07231484Recruiting
Grape study for immune and gut health in obesity
This trial tests if eating grapes every day for 4 weeks can improve your immune system and gut health. It is designed for adults with obesity who are willing to keep their diet and activity stable during the study.
Columbia, MissouriAges 18–60 - NCT07237451Recruiting
Heart and kidney study of SGLT2 inhibitors
This study looks at whether a type of diabetes medicine called SGLT2 inhibitors (also known as flozins) can help protect the heart and kidneys in people with both heart failure with preserved pumping function and moderate chronic kidney disease, with or without diabetes.
IașiAges 18 years+ - NCT07233486Recruiting
Digital health app for fatty liver disease
This trial tests a digital health app designed to help people with metabolic-associated fatty liver disease (MAFLD). The app provides diet and exercise guidance to improve liver health.
Hangzhou, ZhejiangAges 18–65 - NCT07231510Recruiting
Chlordecone exposure and female fertility study
This study looks at how exposure to chlordecone, a chemical found in some Caribbean soils, might affect a woman's ability to get pregnant. You may be asked to share your medical history and provide samples to help us understand this link.
Pointe-à-PitreAges 18–39 - NCT07231341Recruiting
Insulin resistance study in gestational diabetes
This study looks at insulin resistance in pregnant women with gestational diabetes. It aims to understand how the body uses insulin during pregnancy to help improve care for women with this condition.
AarhusAges 18 years+ - NCT07233434Recruiting
Diabetes screening with sugar drink test in Guadeloupe
This study checks if a special sugar-drink test can find type 2 diabetes in people whose fasting blood sugar is normal but whose HbA1c is slightly high. It is for adults 18–64 of African or Indian descent with certain risk factors.
Pointe-à-Pitre, GuadeloupeAges 18–65 - NCT07236177RecruitingEarly Phase 1
Enzyme test for early breast, lung, or pancreatic cancer
This study tests a new blood test that measures enzyme activity to detect localized cancer. It is for people with newly diagnosed, untreated breast, lung, or pancreatic cancer, as well as healthy volunteers.
PoitiersAges 18 years+ - NCT07233265Recruiting
Comparing two surgical methods for undescended testicle in boys
This study compares a newer single-incision scrotal surgery with the standard two-incision inguinal surgery to fix an undescended testicle in boys under 10 years old. The goal is to see which method works better.
Faisalābad, Punjab ProvinceAges 1–10 - NCT07235566RecruitingPhase 2
MRG003 plus pucotenlimab for advanced thyroid cancer (ATC/PDTC)
This trial tests two drugs together: MRG003 (a targeted therapy that delivers chemo directly to EGFR-positive cancer cells) and pucotenlimab (an immunotherapy that helps your immune system attack the cancer). It is for people with a rare and aggressive thyroid cancer (ATC or PDTC) whose tumors have the EGFR protein and have grown despite previous treatment.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07233148Recruiting
ALS, MND, or PLS registry study
This observational study creates a registry for people with ALS, MND, or PLS. It helps researchers better understand these conditions and find possible treatments.
Park City, UtahAges 18–110 - NCT07237373Recruiting
Heat ablation for benign thyroid nodules
This trial tests a minimally invasive procedure called thermal ablation (using heat) to shrink benign thyroid nodules that cause symptoms like pressure or cosmetic issues, or overactive (hot) nodules. It offers an alternative to surgery or radioactive iodine.
BrugesAges 18 years+ - NCT07235111Recruiting
Studying biomarkers for neurodegenerative diseases
This study is looking for people with neurodegenerative diseases (like Alzheimer's, Parkinson's, ALS) to help researchers find new markers in the body that could help understand these conditions better and possibly lead to better treatments.
Genoa, GenoaAges 18 years+ - NCT07236879Recruiting
AI eye test for diabetes patients in primary care
This trial uses an artificial intelligence (AI) system to check for diabetic eye disease (retinopathy) during your regular doctor visit. It aims to detect problems early so you can get treatment sooner.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT07239167Enrolling by invitation
Weight change study for adults with obesity
This study looks at how weight changes affect health in adults with obesity. You may qualify if you have a high BMI and are willing to try a weight loss program.
Taipei, Zhongzheng DistAges 18 years+ - NCT07236788Recruiting
Iron infusion to prevent anemia and improve life in obese patients
This trial tests whether giving an intravenous iron supplement (ferric derisomaltose) can help prevent anemia and improve quality of life in obese patients who have low iron stores. It aims to see if this treatment can boost energy and reduce fatigue.
BeijingAges 18–65
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,627 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,981 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.