Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,607 recruiting studies in this area right now.
By phase
- Not applicable5,335
- Phase 2607
- Phase 1557
- Phase 3417
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 385
Top conditions
- Obesity619
- Ovarian Cancer336
- Pancreatic Cancer289
- Type 2 Diabetes276
- Diabetes192
- Diabetes Mellitus183
- Diabetes Mellitus, Type 2170
- Hypertension138
- Type 1 Diabetes130
- Metabolic Syndrome126
- Obesity & Overweight123
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Colorectal Cancer92
- Pancreas Cancer90
- Endometrial Cancer87
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center41
- Massachusetts General Hospital41
- Eli Lilly and Company40
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland180
- Alabama176
- Arizona170
- Florida166
- Texas158
- Massachusetts151
- New York142
- Colorado115
- Pennsylvania113
Recruiting studies7,607 total
- NCT05709769Recruiting
Radiation-related nutrition therapy guided by scan features
This study looks at whether using scan “patterns” (radiomics) to detect malnutrition risk can guide nutrition therapy for people treated for cervical cancer. It may help improve tolerance of treatment and outcomes by targeting nutrition early.
Hangzhou, ZhejiangAges 18–80 - NCT05962190Recruiting
Short-term extra fat intake to study liver metabolism
This study tests what happens to the liver and fat metabolism when you eat extra fat for a short time. It may help researchers understand how diet affects liver function and metabolism in otherwise stable adults.
OxfordAges 18–65 - NCT05869474Recruiting
Iodine seed implant plus chemotherapy for metastatic pancreatic cancer
This trial studies whether placing iodine-125 radioactive seeds during a procedure, along with chemotherapy, can improve outcomes for people with pancreatic cancer that has spread to other organs. It aims to test a treatment that targets the tumor area while systemic chemotherapy works throughout the body.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT05974696Recruiting
Registry for aggressive pituitary tumors (Aggressive PitNETs)
This study is a research registry that collects information from people with aggressive pituitary tumors. It may help researchers better understand these tumors by building a large, shared dataset over time.
LyonAges 18 years+ - NCT05987631Recruiting
Predicting weight loss and health after weight loss surgery
This study looks at why some people lose more weight and improve their health more than others after bariatric surgery. It also has a subgroup that specifically studies people who are insulin resistant (a sign of prediabetes) to see how surgery affects their metabolism.
Gouda, South HollandAges 18–75 - NCT05994274Recruiting
Heart transplant, cholesterol, and organ rejection study
This study looks at whether changes in blood fats (cholesterol and triglycerides) after a heart transplant are linked to the risk of organ rejection. It may help doctors better monitor and protect your new heart.
WuhanAges 18 years+ - NCT05991856Recruiting
Comparing ablation vs. surgery for adrenal tumors causing high blood pressure
This trial compares two treatments—ultrasound-guided ablation and laparoscopic adrenalectomy—for a type of adrenal tumor called aldosterone-producing adenoma (APA) that causes high blood pressure and low potassium. The goal is to see which treatment works better for patients with a single, non-cancerous tumor.
Guangzhou, GuangdongAges 18 years+ - NCT05994365Recruiting
Testing anlotinib for advanced thyroid cancer that resists radioactive iodine
This trial tests a targeted therapy pill (anlotinib) for people with advanced thyroid cancer that stopped responding to radioactive iodine. It may slow tumor growth or shrink tumors.
Beijing, Beijing MunicipalityAges 18–75 - NCT03637569Recruiting
Skinfold fat measurement and survival in certain digestive cancers
This study looks at whether a simple measurement of fat under the skin (taken at the back of the upper arm) relates to how long people live. It includes adults newly diagnosed with pancreatic, bile duct, or gallbladder cancer who are starting treatment.
SeoulAges 18 years+ - NCT05046483Recruiting
Blood sugar study after a new heart attack
This study measures how your body handles sugar and related hormones in people after a new STEMI heart attack, and compares them with people who do not have diabetes or have prediabetes. The goal is to better understand metabolic changes after the event, which could help future care.
Düsseldorf, North Rhine-WestphaliaAges 18–80 - NCT06013189Recruiting
Adjusting gas flow during heart-lung machine rewarming
This study tests how adjusting the amount of sweep gas (a gas mixture) during the rewarming phase of heart-lung machine use might affect patients. It's for people having planned heart surgery with a standard heart-lung machine, not minimally invasive or robotic surgery.
Istanbul, AltunizadeAges 18 years+ - NCT06015802Recruiting
Predicting pituitary tumor behavior with markers and scans
This study looks at whether blood and tissue markers, along with imaging features, can predict how aggressive a pituitary neuroendocrine tumor is and how it may affect long-term health. It aims to improve treatment decisions by better understanding these tumors.
Guangzhou, GuangdongAges 18–70 - NCT06012227Recruiting
Cheese and metabolic health in middle age
This study looks at how eating cheese affects your body's ability to use energy (metabolic flexibility). It is for healthy middle-aged adults who are not overweight and do not have metabolic conditions like diabetes.
Monserrato, CagliariAges 45–65 - NCT05488288RecruitingPhase 3
Weight-loss surgery plus mesh repair for ventral hernia
This trial tests whether combining weight-loss surgery with a mesh repair for a midline ventral hernia works better and is safer than another approach. It may help people who have both severe obesity and a specific type of hernia reduce hernia problems after surgery.
ColombesAges 18–60 - NCT04743479Recruiting
AI screening for pancreatic cancer in higher-risk people
This trial uses an artificial-intelligence tool to help detect pancreatic cancer earlier and track people at higher risk. You may be asked to complete questionnaires and have imaging tests like MRI or CT to see how well the approach works.
ShanghaiAges 50–75 - NCT04463316Recruiting
Clinic study for people with rare genetic conditions
This study is for people who have a rare syndrome or rare congenital condition and are seen at a rare-disease clinic. It aims to better understand these conditions and how care works in a team setting, which may help guide future treatment decisions.
Rotterdam, South HollandAges 18 years+ - NCT03692884Recruiting
Diabetes registry study for people under 75
This study collects information about people with diabetes to better understand the condition in everyday life. It may help improve future diabetes care by building a real-world diabetes database.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT03224312Recruiting
Study of primary aldosteronism in people with high blood pressure
This trial studies people with high blood pressure caused by a hormone problem called primary aldosteronism. If you qualify, the study may help doctors learn better ways to identify and manage this specific cause of blood pressure elevation.
Chongqing, Chongqing MunicipalityAges 18–80 - NCT06043921Recruiting
Personalized blood test for pancreatic cancer
This study uses a personalized blood test to look for tiny pieces of tumor DNA in people with pancreatic cancer. It helps doctors understand how the cancer changes during treatment.
KashiwaAges 20 years+ - NCT06028724Recruiting
Looking for cancer mutations using a blood test
This study uses a blood test (liquid biopsy) to find genetic changes in advanced solid tumors. It may help doctors choose the right treatment and monitor how well it works over time.
Aviano, PordononeAges 18 years+ - NCT04529889Recruiting
Study of gestational diabetes during pregnancy and child outcomes
This study follows pregnant people with gestational diabetes to see how it affects mothers and babies over time. The team may use this information to better understand risks and care for both you and your child.
Guangzhou, GuangdongAges Any age - NCT05383092Recruiting
Exercise program for kids with cancer and healthy insulin
This trial studies an adapted exercise (physical activity) program for children starting treatment for cancer to see if it can improve insulin sensitivity. It may help kids feel better and support healthy body metabolism during treatment.
ToulouseAges 5–18 - NCT06043466RecruitingPhase 1
CAR-T cell therapy for CEA-positive advanced solid tumors
This trial tests a new cell therapy called CAR-T that targets cancer cells with a protein called CEA. It is for people with certain advanced cancers that have not responded to standard treatments.
Hangzhou, ZhejiangAges 18 years+ - NCT05124457RecruitingPhase 2
Detemir vs NPH insulin for diabetes in pregnancy
This Phase 2 study compares two types of insulin—insulin detemir vs NPH—to see which works better and is safe for controlling blood sugar during pregnancy. You may be invited if you are pregnant and need insulin for either pre-existing type 2 diabetes or gestational diabetes.
Los Angeles, CaliforniaAges 18 years+
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,607 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,814 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.