Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,627 recruiting studies in this area right now.
By phase
- Not applicable5,353
- Phase 2607
- Phase 1557
- Phase 3419
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 385
Top conditions
- Obesity618
- Ovarian Cancer337
- Pancreatic Cancer287
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2172
- Hypertension138
- Type 1 Diabetes131
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Cardiovascular Diseases105
- Overweight105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland179
- Alabama176
- Arizona170
- Florida166
- Texas158
- Massachusetts151
- New York144
- Colorado115
- Pennsylvania114
Recruiting studies7,627 total
- NCT06832202RecruitingPhase 2
HLX22 plus Enhertu for HR+, HER2-low breast cancer
This trial tests a new drug, HLX22, combined with Enhertu (trastuzumab deruxtecan) for people with advanced breast cancer that is hormone receptor positive and HER2-low. The goal is to see if the combination works better than Enhertu alone.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06940414Recruiting
Study of high potassium in kidney disease patients in community
This study looks at how common high potassium levels are in people with chronic kidney disease who are not on dialysis. It may help find who is at risk and how to prevent it.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06933472RecruitingPhase 3
Study of a new phosphate binder for dialysis patients
This trial tests a new drug called AP301 to lower high phosphate levels in people on dialysis. It's designed to help control phosphate, which can be hard to manage with diet and current medications.
Granada Hills, CaliforniaAges 12 years+ - NCT06937086RecruitingPhase 3
Mirikizumab plus tirzepatide for UC with obesity
This study tests whether adding mirikizumab to the weight-loss drug tirzepatide helps people with moderate-to-severe ulcerative colitis who also have obesity or overweight. It aims to see if the combination reduces bowel inflammation and helps with weight management.
Dothan, AlabamaAges 18–70 - NCT06940193Enrolling by invitation
Egoo Phe home test for phenylalanine levels in PKU
This study tests a new home blood test (Egoo Phe) for measuring phenylalanine levels in people with PKU, as well as in healthy adults. It aims to see if it is accurate and easy to use.
BirminghamAges Up to 3 years - NCT06934408RecruitingPhase 1
Safety study of HRS-5817 injection in healthy adults
This early-phase trial tests the safety and tolerability of a new injection called HRS-5817 in healthy volunteers. It helps researchers understand how the drug moves through the body and what side effects it might have.
Hefei, AnhuiAges 18–55 - NCT06940336RecruitingPhase 4
Testing tafamidis for transthyretin amyloid polyneuropathy
This trial tests whether the drug tafamidis can help people with a specific type of nerve damage caused by abnormal protein buildup. It aims to slow or improve symptoms in adults with this condition.
JinanAges 18–80 - NCT06941532Recruiting
Study of GMP powder for PKU and tyrosinemia
This trial tests a new powdered protein substitute (GMP) for people with PKU or tyrosinemia. It aims to see if it is a safe and effective option to help manage their condition.
BirminghamAges 3 years+ - NCT06939673Recruiting
Miro3D wound matrix for healing wounds and ulcers
This trial tests a special wound dressing called Miro3D that helps heal open wounds and ulcers. It may be a good option if you have a wound that is not healing, especially if it has tunnels or pockets under the skin.
Coconut Creek, FloridaAges 18 years+ - NCT06938685Recruiting
Testing a new wound treatment for diabetic foot ulcers
This trial tests a new wound covering called NeoThelium FT to help diabetic foot ulcers heal. It is for people whose ulcer has not improved much with standard care and is not infected or too deep.
Alexandria, LouisianaAges 18 years+ - NCT06941025Recruiting
Safety of Elfabrio in pregnant and breastfeeding women with Fabry disease
This study follows women with Fabry disease who took the medicine Elfabrio during pregnancy or breastfeeding to see if it is safe for them and their babies. It helps doctors learn more about how this treatment affects mothers and infants.
Washington D.C., District of ColumbiaAges Any age - NCT06937203RecruitingPhase 1/Phase 2
A new obesity drug study for people with or without type 2 diabetes
This early-stage study tests an investigational drug called ARO-ALK7 to see if it helps adults with obesity lose weight. It includes people who have type 2 diabetes as well as those who do not, and requires that you have tried to lose weight with lifestyle changes in the past.
Morayfield, QLCAges 18–65 - NCT06938269RecruitingPhase 1
Study of MWN109 tablets in healthy adults
This trial tests a new tablet called MWN109 in healthy adults to see how safe it is and how the body handles it. It has two parts: one for people with a wide range of body weights, and another specifically for people with higher body weight. The results will help guide future studies.
Adelaide, South AustraliaAges 18–60 - NCT06939686Recruiting
Wound matrix study for diabetic foot ulcers
This study tests a new wound dressing made from pig tissue to help heal diabetic foot ulcers. It may help you if you have a foot sore that hasn't healed after 4 weeks of regular care.
Coconut Creek, FloridaAges 18 years+ - NCT06937099RecruitingPhase 3
Testing two drugs for Crohn's with weight issues
This trial tests two study drugs, mirikizumab and tirzepatide, in people with moderate to severe Crohn's disease who also have overweight or obesity. The goal is to see if these treatments can help control Crohn's symptoms and inflammation.
Dothan, AlabamaAges 18–70 - NCT06937177RecruitingPhase 2
Testing mifomelatide to help maintain weight during chemo
This trial tests an investigational drug called mifomelatide (TCMCB07) to see if it can help people with newly diagnosed colorectal or pancreatic cancer maintain a healthy weight while receiving certain types of chemotherapy. You would give yourself a daily injection under the skin.
Tucson, ArizonaAges 18 years+ - NCT06934655RecruitingPhase 3
Starting semaglutide again after weight-loss surgery in teens
This trial tests if restarting semaglutide (a weekly injection for weight loss) soon after sleeve gastrectomy helps teens with severe obesity keep losing weight. It is for patients who were already taking semaglutide before their surgery.
Los Angeles, CaliforniaAges 12–18 - NCT06941740Enrolling by invitation
Blood sugar dips and thinking in early or late sleep types
This study looks at how low blood sugar after eating affects thinking and memory in people who are either early birds or night owls. It may help understand if sleep type changes how your brain handles blood sugar dips.
Paderborn, North Rhine-WestphaliaAges 18–25 - NCT06938152RecruitingPhase 4
Comparing two bone-strengthening drug schedules for osteoporosis
This trial tests whether switching between two medications (Romosozumab and Denosumab) using a cycle or sequence schedule works better for improving bone density in postmenopausal women with severe osteoporosis. It aims to find the most effective treatment plan.
TaipeiAges 50–90 - NCT06938542Enrolling by invitation
Palliative care needs for kids with rare diseases
This study asks children with rare diseases and their families about what kind of palliative care (comfort and support) they need. It aims to understand how to better help families through their child's illness.
Washington D.C., District of ColumbiaAges 1–99 - NCT06933212Recruiting
Mediterranean diet for CADASIL and CAA
This trial is testing whether a Mediterranean diet (rich in fruits, vegetables, whole grains, and healthy fats) can help people with CADASIL or cerebral amyloid angiopathy (CAA) — two conditions that affect blood vessels in the brain. If you have one of these diagnoses, the study may help you understand how diet can support your brain health.
MilanAges 18 years+ - NCT06937320Enrolling by invitationPhase 2
Testing ketone supplements for heart failure with preserved ejection fraction (HFpEF)
This study tests whether a special dietary supplement (ketone esters) can improve exercise ability and heart function in people with a type of heart failure where the heart pumps well but is stiff (HFpEF). You might join if you have stable symptoms, an ejection fraction of 50% or higher, and signs of fluid buildup in the heart.
Durham, North CarolinaAges 18 years+ - NCT06939023Recruiting
Robot vs. keyhole surgery for left-side pancreas growths
This trial compares robot-assisted surgery with standard keyhole surgery to remove growths on the left side of the pancreas. It may help doctors determine which method is safer and more effective for non-cancerous or pre-cancerous conditions.
AmsterdamAges 18 years+ - NCT06941857RecruitingPhase 2
Immunotherapy plus chemotherapy for advanced pancreatic cancer
This trial tests a new combination of drugs (NC410 plus chemotherapy and nivolumab, with or without ipilimumab) for people with metastatic pancreatic cancer who haven't had treatment yet. The goal is to see if adding these immunotherapy agents can help shrink or control the tumor.
Baltimore, MarylandAges 18 years+
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,627 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,981 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.