Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,628 recruiting studies in this area right now.
By phase
- Not applicable5,351
- Phase 2606
- Phase 1560
- Phase 3419
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 386
Top conditions
- Obesity618
- Ovarian Cancer336
- Pancreatic Cancer288
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2172
- Hypertension138
- Type 1 Diabetes132
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland179
- Alabama176
- Arizona170
- Florida165
- Texas159
- Massachusetts151
- New York142
- Colorado115
- Pennsylvania114
Recruiting studies7,628 total
- NCT05752604Recruiting
Study of treatments and factors in thyroid cancer
This study looks at thyroid cancer and how standard treatments and other health details relate to outcomes. You might be eligible if you have thyroid cancer and can participate by giving informed consent.
MilanAges Any age - NCT05964712Recruiting
Therapies for acromegaly and effects on body movement
This study looks at how treatments for acromegaly affect how you function and move, especially in your hands, feet, and overall body structure. You may be asked to do assessments to understand changes over time and whether certain groups respond differently.
MilanAges 18–90 - NCT06169033Recruiting
Can belly fat scans predict weight-loss surgery success?
This study looks at how fat around your belly and inside your abdomen, seen on a CT scan, can predict how well bariatric (weight-loss) surgery will work for people with type 2 diabetes.
BeijingAges 16–70 - NCT06439654Recruiting
Optimizing cholesterol treatment for heart health
This trial helps people with high cholesterol or a history of heart disease find the best treatment to lower their risk of future heart problems. It tests a program to optimize lipid-lowering therapy.
Clark, New JerseyAges 18–120 - NCT06338631Recruiting
Early kidney check in people with excess weight
This study looks for early signs of kidney problems in people with excess weight, even if they are otherwise healthy. It aims to understand how weight affects kidneys before any disease develops.
MilanAges 18–60 - NCT06723236RecruitingPhase 1
Study of MGC028 for Advanced Solid Tumors
This study tests a new drug called MGC028 for people with certain advanced solid tumors that have not responded to standard treatments. The goal is to see if the drug is safe and effective.
San Francisco, CaliforniaAges 18 years+ - NCT06717295Recruiting
Blood test to find cancer early and track treatment
This study uses a blood test that looks at your platelets and immune cells to find common cancers early, and for certain cancers, to monitor how well treatment is working.
RosarioAges 40–75 - NCT00929006RecruitingEarly Phase 1
Testing progesterone effects on hormone timing during sleep in teens
This early-phase study tests whether a progesterone medicine can change when “luteinizing hormone” (a puberty-related hormone) pulses during wake versus sleep. It focuses on pubertal girls with either normal or higher-than-expected testosterone levels to see how their hormone timing responds.
Charlottesville, VirginiaAges 10–17 - NCT05443100Recruiting
Testing whole-body cold therapy for metabolic, neurologic, or fibromyalgia pain
This trial studies whether a whole-body cold therapy called “WBC” can help people with certain metabolic conditions, neurologic conditions, or fibromyalgia. You may be able to join if you meet age and weight requirements and don’t have certain medical or safety risks.
Oggebbio, Verbano-Cusio-OssolaAges 18–65 - NCT03401047RecruitingEarly Phase 1
Estradiol patch study for hormone signaling in PCOS
This early-stage study tests whether adding an estrogen skin patch (estradiol) can change how your body releases key reproductive hormones in adults with PCOS. It may help researchers better understand PCOS-related hormone control and signaling.
Charlottesville, VirginiaAges 18–30 - NCT03068910RecruitingEarly Phase 1
Study of hormone timing in teens with high androgens
This early study looks at how certain “male-type” hormones and brain signals (measured through hormone patterns during the day and night) work in adolescent girls with high androgen levels. It may help researchers better understand causes like PCOS and related hormone timing differences.
Charlottesville, VirginiaAges 10–17 - NCT04723862RecruitingEarly Phase 1
Spironolactone to test sleep hormone patterns in teen girls
This early-phase study tests whether spironolactone can “normalize” a key hormone timing pattern during sleep and wake cycles in mid-to-late pubertal girls who have high male-hormone levels. The goal is to learn how this medicine may affect hormone rhythms related to conditions like PCOS.
Charlottesville, VirginiaAges 10–17 - NCT06720844Recruiting
Precocious puberty and related brain conditions study
This study looks at children with central precocious puberty (early puberty that starts in the brain) to see how often it's linked with other developmental issues. It compares how these children develop and respond to treatment.
Bologna, BolgonaAges Up to 18 years - NCT06719102Recruiting
Support for mothers and caregivers with new babies
This study looks at how mothers and other caregivers can help their babies grow and thrive. You and your baby would be videotaped during some play and feeding sessions to understand your interactions better.
Austin, TexasAges birth–90 years - NCT06723925Recruiting
Biotinidase deficiency newborn screening and follow-up study
This study looks at babies who had low biotinidase enzyme activity on their newborn screening test. It aims to understand the genetic cause and track their health over time. If your child had low activity on this test, this study may help provide important follow-up care.
Bologna, BolognaAges Up to 3 years - NCT06720597Recruiting
Testing a device for blood vessel health in erectile dysfunction
This study tests a device called EndoPAT to check how well the blood vessels in your penis are working. It may help doctors better understand erectile dysfunction or low testosterone.
Newport Beach, CaliforniaAges 18 years+ - NCT06724991Enrolling by invitation
Lower vs standard insulin dose for high potassium in ER
This study compares a lower dose versus a standard dose of insulin and dextrose (sugar water) to treat moderately high potassium levels in emergency department patients. It aims to see if a lower dose works just as well with fewer side effects.
Kuala LumpurAges 18–100 - NCT06722521RecruitingPhase 4
Comparing two treatments for high coronary calcium without symptoms
This trial compares a combo of statin and ezetimibe without aspirin against statin alone with aspirin in people with high coronary calcium but no blocked arteries. It aims to find which approach is safer and more effective without causing bleeding risk.
SeoulAges 19 years+ - NCT06726642Recruiting
Blood test study for people with inherited cancer risk
This study looks for DNA fragments in blood of people with certain inherited cancer syndromes. It may help find cancer earlier or guide better monitoring. You would give blood samples every 4 months (if in the experimental group).
Vancouver, British ColumbiaAges Up to 90 years - NCT06723938Recruiting
Understanding genetic causes of differences in sex development
This study looks at the genetic and physical traits of people with 46,XY DSD (differences in sex development). It aims to better understand the causes and improve care.
Bologna, BolognaAges Up to 18 years - NCT06724406Recruiting
Family weight loss program for Black adults
This study tests a family-centered weight loss program for Black adults and their family members. You and a family member or partner will work together to lose weight and improve health.
Chapel Hill, North CarolinaAges 18–75 - NCT06726590Recruiting
Gene testing for better medication outcomes
This study collects blood, urine, and cheek swabs, along with health information, to see how your genes affect your response to medications. You may be eligible if you take many medications or are on blood pressure or depression medication.
Bryan, TexasAges 18 years+ - NCT06722443Enrolling by invitation
Probiotics and Prebiotics for Obesity
This trial tests whether adding probiotics and prebiotics to your diet can help with obesity and related health problems like prediabetes, diabetes, high cholesterol, or high blood pressure.
Granada, SpainAges 18–75 - NCT06719947RecruitingPhase 2/Phase 3
Brain stimulation for ALS: a controlled trial
This study tests whether a non-invasive brain stimulation technique called HD-tDCS can help people with ALS. It is a randomized trial, meaning participants are assigned by chance to receive the real stimulation or a placebo, to see if it slows disease progression.
Brasília, Federal DistrictAges 18–80
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,628 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 12,015 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.