Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,628 recruiting studies in this area right now.
By phase
- Not applicable5,351
- Phase 2606
- Phase 1560
- Phase 3419
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 386
Top conditions
- Obesity618
- Ovarian Cancer336
- Pancreatic Cancer288
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2172
- Hypertension138
- Type 1 Diabetes132
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland179
- Alabama176
- Arizona170
- Florida165
- Texas159
- Massachusetts151
- New York142
- Colorado115
- Pennsylvania114
Recruiting studies7,628 total
- NCT06545942RecruitingPhase 1
Studying MOMA-313 for advanced or metastatic solid tumors
This trial tests a new oral drug, MOMA-313, alone or with another drug (olaparib), in people whose cancer has a specific DNA repair problem (HR-deficient mutation). It aims to see if the drug can shrink tumors or slow their growth.
Goodyear, ArizonaAges 18 years+ - NCT06544863Recruiting
Better support for cirrhosis and liver transplant patients
This study tests a new care support program for people with cirrhosis or who have had a liver transplant. It aims to improve how patients are followed and helped at the hospital.
ParisAges 18 years+ - NCT06541548Recruiting
Bone health study for bone and muscle loss conditions
This study uses special imaging to compare bone structure in people with conditions that cause bone or muscle loss vs. those with back pain. It aims to better understand bone health in different diseases.
Saint-EtienneAges 18 years+ - NCT06540729RecruitingPhase 2
Combination treatment for ovarian clear cell cancer
This trial tests a combination of three drugs (RC48, AK104, and bevacizumab) for ovarian clear cell carcinoma, a type of ovarian cancer. The goal is to see if this combination can help shrink or control the cancer in people who have not had many prior treatments.
Guanzhou, GuangdongAges 18–75 - NCT06548828Recruiting
Reducing sweeteners in pregnancy and breastfeeding
This study tests whether lowering non-nutritive sweetener (like diet soda) intake during pregnancy and while breastfeeding can improve health for both you and your baby.
Washington D.C., District of ColumbiaAges 18–45 - NCT06542939Enrolling by invitation
Telehealth for diabetes and hypertension in South Asians
This study tests a telehealth program to help South Asian adults manage both diabetes and high blood pressure. If you have these conditions and your blood pressure is not well controlled, this program could help you improve your health from home.
Atlanta, GeorgiaAges 21 years+ - NCT06539624Recruiting
Testing a new gene therapy for Fabry disease
This trial is testing a new treatment called EXG110 for people with Fabry disease. It's designed to see if it's safe and if it can help. You may be able to join if you have a confirmed diagnosis and at least one symptom of Fabry disease.
Shanghai, Shanghai MunicipalityAges 7 years+ - NCT06541535RecruitingPhase 4
Fluid treatment for severe diabetic ketoacidosis
This trial tests two types of fluids (saline or Ringer's lactate) to see which works better for people with severe diabetic ketoacidosis. Results could help doctors choose the best fluid replacement in this emergency.
NiceAges 18 years+ - NCT06545721Recruiting
Weight changes and hormone health in PCOS
This study looks at how weight changes affect hormone levels and insulin resistance in women with PCOS. It may help understand if weight cycling is harmful or helpful.
Beijing, Beijing MunicipalityAges 18–45 - NCT06546085Recruiting
Extracellular vesicles, insulin, and exercise in type 2 diabetes
This study looks at how tiny particles called extracellular vesicles affect how your body uses insulin, and whether exercise can make a difference. It is for people with type 2 diabetes (or normal blood sugar) who are not very active and have been on diabetes medication for a long time.
New Brunswick, New JerseyAges 30–80 - NCT06544954Recruiting
Grape study for heart and gut health in overweight women
This study tests whether eating California grapes can improve gut health and heart health in overweight or obese women who have been through menopause and may have type 2 diabetes or metabolic syndrome. You would need to eat grapes daily and provide blood and stool samples.
Davis, CaliforniaAges 45–70 - NCT06538220Recruiting
A study on care for obese patients in a chronic disease unit
This study looks at how well a special care program works for people with obesity. It aims to improve health and quality of life through a dedicated chronic disease unit.
La Garde, VarAges 18 years+ - NCT06533865RecruitingPhase 3
Romosozumab and estrogen for bone loss from missed periods
This study tests whether a bone-building medication (romosozumab) combined with estrogen replacement therapy can improve bone density in young women with hypothalamic amenorrhea (missing periods due to low energy or stress). It aims to find a better treatment for low bone density caused by this condition.
Boston, MassachusettsAges 14–30 - NCT06533007Enrolling by invitation
How PDE3B affects metabolism in healthy adults
This study looks at how a protein called PDE3B affects your body's metabolism (how it uses energy). It may help researchers understand weight and insulin resistance better, which could lead to new treatments.
CambridgeAges 21–75 - NCT06538948Recruiting
Eating behavior after weight loss surgery
This study measures how people eat and how their gut hormones change after weight loss surgery. It compares different groups to understand differences between men and women.
Männedorf, Canton of ZurichAges 18 years+ - NCT06546696Recruiting
Obesity support program for children and families
This trial offers a 6-month program to help children ages 6–11 with obesity and their parents adopt healthier habits, including exercise and nutrition. It takes place at community centers in Middle Tennessee and provides online training.
Nashville, TennesseeAges 6–12 - NCT06534554Recruiting
Improving gout care after an emergency room visit
This study looks at ways to improve how gout is managed after a visit to the emergency room. It aims to help you get better follow-up care and prevent future flares.
Birmingham, AlabamaAges 18–99 - NCT06546137Recruiting
Registry for inherited heart conditions in Brazil
This study is building a national registry in Brazil to learn more about inherited heart conditions and improve care. If you have a family-related heart disease, you may be able to join and help advance cardiovascular healthcare.
Rio Branco, AcreAges Any age - NCT06533332RecruitingPhase 1
Testing ERX-315 for advanced solid tumors
This trial tests a new drug called ERX-315 for people with advanced solid tumors (like breast, ovarian, pancreatic, endometrial, or liver cancer) that have not responded to standard treatments. The goal is to see if the drug is safe and how well it works.
Ryde, New South WalesAges 18 years+ - NCT06543537Recruiting
A trial to help patients with advanced ovarian cancer plan their visits
This study tests a program to help patients and their doctors work together to set a plan for each visit. If you have advanced ovarian cancer and are getting chemotherapy at Dana-Farber, you may be able to join.
Boston, MassachusettsAges 18 years+ - NCT06547619RecruitingEarly Phase 1
Blood vessel health after pregnancy with diabetes
This study looks at how blood vessels work in women who had a healthy pregnancy or gestational diabetes. It tests if a substance called ET-1 affects blood vessel function.
Iowa City, IowaAges 18–50 - NCT06537921Recruiting
Testing minocycline for depression with obesity
This trial tests whether adding the antibiotic minocycline to your current antidepressant helps people with both depression and obesity. It aims to see if reducing inflammation can improve mood.
LondonAges 18–65 - NCT06545604Recruiting
Yoga and lifestyle program before ovarian cancer treatment
This program offers gentle yoga and lifestyle guidance to help women with advanced ovarian cancer feel stronger and more prepared before chemotherapy and surgery. It is done virtually from home and focuses on your overall well-being.
Houston, TexasAges 18 years+ - NCT06547736RecruitingPhase 2
Precision treatment for advanced pancreatic cancer
This trial tests personalized therapies for people with advanced pancreatic cancer that has spread or cannot be removed. It aims to find the best treatment based on your tumor's unique features.
Shanghai, Shanghai MunicipalityAges 18–75
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,628 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 12,015 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.