Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,628 recruiting studies in this area right now.
By phase
- Not applicable5,351
- Phase 2606
- Phase 1560
- Phase 3419
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 386
Top conditions
- Obesity618
- Ovarian Cancer336
- Pancreatic Cancer288
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2172
- Hypertension138
- Type 1 Diabetes132
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland179
- Alabama176
- Arizona170
- Florida165
- Texas159
- Massachusetts151
- New York142
- Colorado115
- Pennsylvania114
Recruiting studies7,628 total
- NCT06069622Recruiting
How a gene affects weight-loss treatment response
This study looks at how a weight-loss medication affects people with obesity who may have a specific gene difference (caveolin-1). It aims to understand why some people respond differently to GLP-1 treatments like semaglutide.
Boston, MassachusettsAges 18 years+ - NCT06066801Recruiting
Bedside bone biopsy for diabetic foot infection
This trial is testing a new way to take a small sample of infected bone from the foot of people with diabetes. It aims to see if a bedside biopsy is safe and accurate for diagnosing bone infection, so you may avoid more invasive procedures.
ParisAges 18 years+ - NCT06057662Enrolling by invitation
Personalized diabetes support for newly diagnosed children
This study offers personalized support to help families manage type 1 diabetes in a newly diagnosed child. It includes education, monitoring, and guidance from a diabetes team for 2 years.
Sacramento, CaliforniaAges birth–16 years - NCT06073431Recruiting
Study on weight loss types in advanced cancer
This study looks at different types of weight loss (cachexia) in people with advanced lung, pancreatic, or colorectal cancer. Researchers want to find patterns to better understand and treat it. You can join even if you haven't lost weight yet.
Fort Smith, ArkansasAges 18 years+ - NCT06056908Recruiting
Shwachman Diamond Syndrome Registry and Study
This study is creating a registry for people with Shwachman-Diamond Syndrome (SDS) or similar conditions, and their family members. It aims to learn more about the condition and improve care by collecting health information over time.
Aurora, ColoradoAges Any age - NCT06066333RecruitingPhase 2
Radiation and immunotherapy for adrenal cancer with liver spread
This trial tests whether adding a type of immunotherapy (pembrolizumab) to targeted radiation can help people with adrenal cancer that has spread to the liver. It aims to shrink tumors and slow the cancer's growth.
Basking Ridge, New JerseyAges 18 years+ - NCT06073665RecruitingPhase 4
Thyroid hormone dosing in older adults
This study tests whether current thyroid medication doses are appropriate for people aged 65 and older. The goal is to find the best dose for each person to improve well-being.
Philadelphia, PennsylvaniaAges 65 years+ - NCT06072963RecruitingPhase 2
Combining insulin and semaglutide for memory in MCI with metabolic syndrome
This study tests if a combination of insulin and semaglutide (a diabetes drug) can improve memory and thinking in people with mild cognitive impairment (MCI) who also have metabolic syndrome (a cluster of health issues like large waist, high blood sugar, and high blood pressure). It aims to see if treating blood sugar problems helps protect the brain.
Ramat GanAges 60–90 - NCT06071507Recruiting
Comparing treatments for stomach blockage in pancreatic cancer
This trial compares three ways to relieve a stomach or duodenal blockage caused by pancreatic cancer: placing a stent, performing a bypass with a thin tube (endoscopy), or surgical bypass. It aims to find which option helps patients eat and feel better sooner.
ParisAges 18 years+ - NCT06060873Recruiting
Using a blood test to find active germ cell tumors
This trial tests whether a blood test called miRNA-371 can detect active germ cell tumors in patients who have had surgery or are being watched. It may help guide treatment decisions without needing extra biopsies or scans.
Birmingham, AlabamaAges 18 years+ - NCT06072677Recruiting
Mood and testosterone in young teens
This study looks at how mood changes during puberty in young people aged 11 to 14. It tests whether using a mindfulness app (Healthy Minds) can help teens who have been through stress or feel down.
Chapel Hill, North CarolinaAges 11–14 - NCT06063564Recruiting
Testing a digital tool to improve heart health in rural clinics
This study is testing a digital health app called PREVENT to help doctors and patients work together on heart-healthy habits like eating well and being active. It is designed for people in rural areas who want to lower their risk of heart disease.
St Louis, MissouriAges 18–64 - NCT06070194Recruiting
Heart health and eating patterns in short sleepers
This study tests whether changing the time window when you eat can improve heart health for people who naturally sleep 6.5 hours or less per night. You'll be asked to follow either a longer or shorter daily eating period while researchers measure blood pressure and other heart disease risk factors.
Baton Rouge, LouisianaAges 18–45 - NCT06059716Recruiting
Gluten detection and education for new celiac diagnosis
This study helps people newly diagnosed with celiac disease learn to use a gluten-detection device and get education to better manage their diet and health.
Chicago, IllinoisAges 18–75 - NCT06072911Recruiting
Men's health after prostate cancer surgery study
This study looks at how men recover control of urine and sexual function after prostate removal surgery. It also tests if a 12-week exercise program can help improve these functions.
Edmonton, AlbertaAges 18 years+ - NCT06067399Recruiting
Red blood cell width and blood sugar in type 2 diabetes
This study looks at two blood test results—HbA1c (average blood sugar) and red blood cell width (RDW)—in people with type 2 diabetes whose blood sugar is not well controlled. The goal is to see how these two measurements relate after improving blood sugar management.
Al KhārjahAges 40 years+ - NCT06073704Recruiting
Light therapy for gum disease in people with obesity
This study tests whether adding a special light-activated cleaning (antimicrobial photodynamic therapy) to standard gum disease treatment can help people with obesity who have gum disease. It aims to see if this extra step improves gum health more than standard treatment alone.
Bauru, São PauloAges 18–70 - NCT06076252Enrolling by invitation
Comparing two surgical methods for pancreatic cancer
This trial compares a modified surgical technique to the standard one for removing pancreatic tumors. It aims to see if the new method lowers the risk of a leak from the pancreas after surgery.
Zhanjiang, GuangdongAges 18–75 - NCT06057597Recruiting
Comparing two types of gastric bypass surgery for weight loss
This trial compares a new version of gastric bypass (with a longer 150cm bypassed segment) to the standard Roux-en-Y gastric bypass to see which leads to better weight loss and health improvements. It is for people with severe obesity who are already scheduled for surgery and want to help find the best procedure.
ParisAges 18–65 - NCT06067763Enrolling by invitation
Project Health: Preventing unhealthy weight gain in young adults
This study tests a program to help young adults improve their eating and exercise habits, with the goal of preventing obesity. It is designed for people who are concerned about their weight and want to make healthier lifestyle choices.
Stanford, CaliforniaAges 17–20 - NCT06078683Recruiting
Ketone drink for exercise and heart health in type 2 diabetes
This study tests whether a special ketone drink can improve exercise ability and heart function in people with type 2 diabetes. Participants will have two treadmill exercise tests and heart MRI scans to see how the drink affects their performance and cardiac efficiency.
Columbus, OhioAges 18–80 - NCT02143830RecruitingPhase 2
Stem cell transplant chemotherapy for Fanconi anemia
This Phase 2 study tests a stem cell transplant approach using adjusted chemotherapy doses for people with Fanconi anemia. It may help replace damaged bone marrow and treat blood problems like severe aplastic anemia, MDS, or leukemia.
New York, New YorkAges 3 months+ - NCT01818661RecruitingPhase 4
Imaging study for progressive apraxia of speech
This trial uses repeated brain scans to study how progressive apraxia of speech changes over time. It may help doctors better understand the condition and improve future tracking and care.
Rochester, MinnesotaAges 18 years+ - NCT04115254Recruiting
MRI-guided focused radiation for certain tumors
This study tests a type of high-precision radiation guided by MRI pictures to treat certain cancers. It may help doctors deliver radiation more accurately while avoiding nearby healthy tissue, but you must be able to safely complete an MRI scan and meet tumor-size and health requirements.
Boston, MassachusettsAges 18 years+
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,628 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 12,015 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.