Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,628 recruiting studies in this area right now.
By phase
- Not applicable5,351
- Phase 2606
- Phase 1560
- Phase 3419
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 386
Top conditions
- Obesity618
- Ovarian Cancer336
- Pancreatic Cancer288
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2172
- Hypertension138
- Type 1 Diabetes132
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland179
- Alabama176
- Arizona170
- Florida165
- Texas159
- Massachusetts151
- New York142
- Colorado115
- Pennsylvania114
Recruiting studies7,628 total
- NCT02641145Recruiting
PET/MRI scans in light-chain amyloid heart disease
This study uses special PET and heart MRI scans to better understand light-chain amyloidosis affecting the heart. The scans may help researchers see how the disease behaves in different patient groups and treatment states.
Boston, MassachusettsAges 18–99 - NCT04473833Recruiting
Transvaginal ultrasound screening for ovarian cancer risk
This study tests whether a transvaginal ultrasound can be used as a screening tool for ovarian cancer in women at higher risk. It may help find ovarian cancer earlier in people who have a strong family or personal cancer history.
Lexington, KentuckyAges 24 years+ - NCT05704036RecruitingPhase 4
Estrogen use and bone health in women with cystic fibrosis
This observational study looks at how taking (or not taking) estrogen affects bone health in women with cystic fibrosis (CF). If you may have low estrogen, it also explores whether estrogen levels and symptoms relate to bone density over time.
Baltimore, MarylandAges birth–100 years - NCT05024929Recruiting
Test targeted drugs to help radioactive iodine reach thyroid cancer
This study looks at whether certain cancer “targeted therapy” medicines can make radioactive iodine (RAI) therapy work better for thyroid cancer that has spread to the lungs. It also involves taking special whole-body scans to measure how much radioactive iodine gets taken up by the cancer.
San Francisco, CaliforniaAges birth+ - NCT06041516RecruitingPhase 1
New drug ADCT-701 for neuroendocrine and nerve tumors
This trial tests a new drug called ADCT-701 for people with certain rare cancers (neuroendocrine tumors, adrenal cancer, or a type of nerve tumor) that have come back or spread. The drug is an antibody-drug conjugate, which works like a targeted missile to kill cancer cells while trying to spare healthy ones.
Bethesda, MarylandAges 18–120 - NCT06044935Recruiting
Nicotinamide riboside for fat burning and metabolism
This study tests whether a supplement called nicotinamide riboside (a form of vitamin B3) helps the body burn fat more efficiently during exercise. It may be a good option if you are overweight or have a specific type of diabetes (MODY2) and want to see if a natural supplement can boost your metabolism.
Bethesda, MarylandAges 18–65 - NCT06036693Recruiting
MPS Long-Term Study
This study follows people with MPS, a rare genetic condition, to learn more about the disease over time. If you have a confirmed MPS diagnosis, you may be able to join.
AngersAges Any age - NCT06051695RecruitingPhase 1/Phase 2
CAR T cell therapy for mesothelin-positive solid tumors
This trial tests a new type of immune cell therapy (CAR T-cells) designed to target cancer cells that have a protein called mesothelin but have lost a marker that lets them hide from the immune system. It's for people with advanced solid tumors who have already tried standard treatments.
Gilbert, ArizonaAges 18 years+ - NCT06056297RecruitingPhase 3
Study of Mavorixafor for chronic neutropenia with infections
This trial tests if mavorixafor can help people with certain types of long-term low neutrophil counts (chronic neutropenia) who still get frequent or serious infections. It aims to reduce infection risk by boosting your body's infection-fighting cells.
Phoenix, ArizonaAges 12 years+ - NCT06040541RecruitingPhase 1
Study of RMC-9805 for KRAS G12D solid tumors
This trial tests an experimental pill (RMC-9805) for people with solid tumors that have a specific KRAS G12D mutation. It's for those who have already tried other treatments and need new options.
Sacramento, CaliforniaAges 18 years+ - NCT06046651Recruiting
Blood sample collection for lab research
This study collects blood samples from healthy adults to help researchers learn more about how to run lab tests. It involves one visit or at-home collection and might help future medical research.
San Francisco, CaliforniaAges 18 years+ - NCT06041581Enrolling by invitation
Insomnia treatment study for heart health
This study tests whether treating insomnia can help lower your risk for heart disease. If you have trouble sleeping and certain heart risk factors, you may be able to join.
Indianapolis, IndianaAges 40 years+ - NCT06036810Recruiting
Spanish decision tool for ovarian cancer maintenance
This study tests a Spanish-language decision tool to help people with advanced ovarian cancer choose the best maintenance therapy after chemotherapy. It is for patients who can read or speak Spanish and are eligible for maintenance treatment.
Houston, TexasAges 18 years+ - NCT06041789RecruitingPhase 2
Does a memory medication affect bone health?
This study looks at whether a common memory medication (called donepezil) can also help keep your bones strong. If you have memory problems and are willing to start this medication, you might be able to join.
Durham, North CarolinaAges 50 years+ - NCT06051591Recruiting
Food FARMacia: Helping families with food worries
This study tests a program called Food FARMacia to help families with young children who sometimes worry about having enough food. The goal is to see if the program can help prevent childhood obesity by providing support and resources.
Stanford, CaliforniaAges 6 months+ - NCT06051058Recruiting
App for managing health after hospital discharge
This study tests a smartphone app designed to help people with multiple health conditions manage their care after leaving the hospital. It may help you feel more supported and avoid confusion during the transition from hospital to home.
Boston, MassachusettsAges 55 years+ - NCT06046794Recruiting
Gemcitabine for metastatic pancreatic cancer patients
This trial tests gemcitabine chemotherapy in people with metastatic pancreatic cancer who cannot take FOLFIRINOX. It aims to see how well gemcitabine works based on a specific tumor marker called GemCore.
MarseilleAges 18 years+ - NCT06041906Enrolling by invitation
International registry for congenital portosystemic shunt
This registry is gathering information from people who have a rare liver blood vessel problem they were born with (congenital portosystemic shunt). By joining, you help researchers learn more about this condition and improve future care.
New Haven, ConnecticutAges 1 day+ - NCT06031428RecruitingPhase 2
Nurse case management for diabetes in formerly incarcerated Black men
This trial tests a nurse-led program to help formerly incarcerated Black men better manage their type 2 diabetes. The goal is to improve blood sugar control and overall health.
Milwaukee, WisconsinAges 18 years+ - NCT06050317RecruitingPhase 2
Sintilimab plus chemo and radiation for inoperable pancreatic cancer
This trial combines the immunotherapy drug sintilimab with chemotherapy and radiation for people with inoperable locally advanced pancreatic cancer who have not received prior systemic treatment. The goal is to see if this combination shrinks tumors and improves outcomes.
Jinan, ShandongAges 18–75 - NCT06036004RecruitingPhase 2
Oxytocin therapy for anxiety in diabetes insipidus
This trial tests whether oxytocin, a hormone that helps with social bonding and stress, can improve anxiety or emotional awareness in people with central diabetes insipidus (a condition where the body can't regulate water balance). It may be a good fit if you have high anxiety or trouble identifying your feelings.
BerlinAges 18 years+ - NCT06051123Recruiting
Probiotics for ALS and related disorders
This trial tests whether probiotics (healthy bacteria) can help people with ALS. You'll take a probiotic or placebo daily for several months, and researchers will track your symptoms and gut health.
Fredericton, New BrunswickAges 18 years+ - NCT06034405Recruiting
Checking spine tissue for heart amyloidosis signs
This trial is looking at leftover tissue from past spine surgeries to see if it contains signs of a heart condition called TTR amyloidosis. It may help find people who have this condition early.
Beverly Hills, CaliforniaAges 50 years+ - NCT06047574Recruiting
Team care for PCOS diagnosis and treatment
This trial studies whether a team of doctors from different specialties can better diagnose and treat PCOS. If you have PCOS and are looking for a more comprehensive approach, this study may be a good fit.
Shanghai, Shanghai MunicipalityAges 18–45
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,628 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 12,015 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.