Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,639 recruiting studies in this area right now.
By phase
- Not applicable5,357
- Phase 2608
- Phase 1562
- Phase 3419
- Phase 4318
- Phase 1/Phase 2289
- Phase 2/Phase 386
Top conditions
- Obesity618
- Ovarian Cancer337
- Pancreatic Cancer290
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2171
- Hypertension138
- Type 1 Diabetes132
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer112
- Overweight106
- Cardiovascular Diseases104
- Amyotrophic Lateral Sclerosis101
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer89
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California523
- Maryland178
- Alabama175
- Arizona171
- Florida165
- Texas159
- Massachusetts151
- New York142
- Colorado115
- Pennsylvania114
Recruiting studies7,639 total
- NCT05645510Recruiting
Study for people on long-term cancer targeted medicines
This study looks at people who are already taking long-term targeted cancer medicines. It may help researchers understand how these treatments work over time and whether there are ways to improve care.
Edmonton, AlbertaAges 18–90 - NCT05662462Recruiting
Phone coaching to keep blood sugar in range during pregnancy
This study tests whether technology plus coaching can help pregnant people with type 2 diabetes keep their blood sugar in a healthy target range. You may use a smartphone app and, if assigned to that group, a device that tracks glucose continuously.
Columbus, OhioAges 18 years+ - NCT05643144Recruiting
Shared decisions for dementia and diabetes care
This study tests a program that helps people with both memory problems (like dementia or mild cognitive impairment) and diabetes, along with their caregivers, make better care decisions together. It uses a special device to track blood sugar without fingersticks.
Indianapolis, IndianaAges 65 years+ - NCT05649072Recruiting
Mobile mammogram screening study for women with family cancer risk
This study looks at how well mobile mammogram units and video/phone genetics counseling (“telegenetics”) can help women who may have inherited cancer risk. If you’re scheduled for a mammogram through the Project VALET mobile units, this may be an easy option to learn about and address your risk.
Houston, TexasAges 18 years+ - NCT05669742RecruitingPhase 3
Empagliflozin plus olanzapine to reduce metabolic side effects
This trial tests whether adding empagliflozin to standard olanzapine treatment can improve metabolic problems (like blood sugar and cholesterol changes) that can happen with olanzapine in people with schizophrenia. If you qualify, you would be closely monitored for benefits and side effects.
TantaAges 18–65 - NCT05641753RecruitingPhase 4
LDL-lowering study for adults with type 1 diabetes
This study looks at cholesterol lowering in adults with type 1 diabetes and whether it reduces “residual risk,” meaning risk that may remain even with current care. You may be asked to take cholesterol-focused treatment and complete blood tests to track LDL (“bad cholesterol”).
New York, New YorkAges 18–89 - NCT04167033Recruiting
Checking heart rhythm timing in women with premature ovarian insufficiency
This study measures how quickly the heart “recharges” between beats (often shown as QT timing). It compares women with premature ovarian insufficiency to healthy women to understand whether ovarian insufficiency is linked to heart rhythm differences.
BordeauxAges 18–40 - NCT01630850Recruiting
Islet cell transplant for brittle type 1 diabetes
This trial studies whether transplanting insulin-producing islet cells can improve blood sugar control and reduce severe low blood sugar in people with “brittle” type 1 diabetes. It’s meant for adults with long-standing insulin dependence and troublesome, hard-to-control hypoglycemia.
Chicago, IllinoisAges 18–70 - NCT05600933Enrolling by invitation
Providing tumor samples to find new treatment targets
This study collects tumor tissue and related blood tests from people who already need a biopsy or surgery as part of their usual care. Researchers use the samples to learn what drives the tumor and how the tumor environment may affect treatment, which could help develop future therapies.
Bethesda, MarylandAges 18 years+ - NCT05600946Recruiting
Study of body differences in creatine transporter deficiency
This study looks at physical and body features in people with creatine transporter deficiency caused by a specific gene change (SLC6A8). It may help doctors better understand the condition and how it shows up, which can improve future care.
Bethesda, MarylandAges 2–40 - NCT05594992Enrolling by invitationPhase 3
Study extension of JR-141 for long-term Hunter syndrome safety
This is a follow-up study for people who already took JR-141 in an earlier trial for Hunter syndrome (MPS II). It checks how well the treatment works over the long term and monitors long-term safety.
Oakland, CaliforniaAges Any age - NCT05626712RecruitingPhase 1/Phase 2
CELZ-201 to preserve insulin production in early type 1 diabetes
This Phase 1/2 study tests whether CELZ-201 is safe and can help the body keep making some of its own insulin in people who were recently diagnosed with type 1 diabetes. You may be eligible if your diabetes started within the past year and your tests show you still have some insulin-making activity.
Miami, FloridaAges 18–35 - NCT05614219Recruiting
Check if you have high cholesterol from genes
This trial focuses on people referred to a cholesterol (lipid) clinic to help identify inherited high cholesterol. It tests an “interpretive comment” approach to nudge detection—meaning it may help clinicians recognize who is most likely to have familial hypercholesterolemia.
Odense, FunenAges 18 years+ - NCT05610735RecruitingPhase 1/Phase 2
Study drug combination for ovarian cancer after platinum stops working
This Phase 1/2 trial tests a combination treatment for recurrent ovarian, fallopian tube, or primary peritoneal cancer when platinum chemotherapy stops working. If you qualify, the study aims to control the cancer and see how well the treatment is tolerated.
Louisville, KentuckyAges 18 years+ - NCT05632406Recruiting
Breathing training to improve breathing and blood pressure
This study tests whether a breathing device training program can improve breathing and blood pressure. It may help people who have higher blood pressure and may feel out of breath, especially those who have weight-related breathing strain.
Tallahassee, FloridaAges 18–45 - NCT05636111RecruitingPhase 1
Study drug lurbinectedin with weekly paclitaxel and bevacizumab
This Phase 1b trial tests how well a new cancer drug (lurbinectedin) works together with weekly paclitaxel and bevacizumab in ovarian, fallopian tube, or peritoneal cancer that has returned or worsened after platinum chemotherapy. It’s designed to find the best way to use these medicines and check for early signs of benefit and safety.
Houston, TexasAges 18 years+ - NCT05635747Enrolling by invitation
90-day follow-up study for children using RELiZORB
This study follows children who are already taking RELiZORB to see how it’s going over time and whether it remains safe and tolerable, with effects on nutrient absorption. It doesn’t change treatment—it mainly looks at outcomes during the next 90 days.
Los Angeles, CaliforniaAges 2–18 - NCT05623111RecruitingPhase 2
Nerve-area Botox shots for diabetic foot nerve pain
This Phase 2 trial tests whether injecting incobotulinumtoxin-A near painful nerves can reduce nerve-type pain in the feet for people with diabetes. If you have lasting, fairly symmetrical pain in both feet, the injections may help calm the nerve pain signals.
Glostrup MunicipalityAges 18 years+ - NCT05619705Recruiting
Health coaching for pregnant women through home visits
This trial tests a structured health-coaching program delivered during home visits to help pregnant people improve health habits during pregnancy. It may help you with support like tracking weight and following a planned coaching routine.
Baltimore, MarylandAges 18 years+ - NCT05630482Recruiting
Healthy Family program for expecting military parents
This trial tests a “Healthy Family Foundations” program for two-parent military families expecting their first baby. It may help improve family support and parenting readiness during pregnancy and early infancy.
Nellis Air Force Base, NevadaAges 18–60 - NCT05609318Recruiting
Imaging the effects of an IV iron treatment
This study uses MRI scans to look at what happens in the body after you receive intravenous (into a vein) iron to treat low iron levels. It may help doctors understand whether the treatment is working and why.
Oxford, OxfordshireAges 18 years+ - NCT05604963Recruiting
Half or full thyroid surgery for low-risk thyroid cancer
This study looks at people with low-risk thyroid cancer who have already had (or are about to have) surgery, comparing half-thyroid removal versus full-thyroid removal. It may help doctors choose the safest and most effective surgery for your cancer type and risk level.
Crewe, CheshireAges 16 years+ - NCT05633628Recruiting
Wear a continuous glucose monitor with type 2 diabetes
This study checks how well periodic continuous glucose monitoring works for adults with type 2 diabetes. You may be asked to wear a sensor that tracks glucose more often than finger-stick checks, which can help improve day-to-day glucose control.
StockholmAges 18–80 - NCT05628948Recruiting
Donate blood for a heart and metabolism research biobank
This study builds a “biobank,” which is a collection of blood and related samples, to support future research on heart and metabolic (sugar/body-fat) conditions. It may help researchers better understand these diseases and improve future prevention and treatments.
Cleveland, OhioAges 18 years+
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,639 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 12,048 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.