Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,640 recruiting studies in this area right now.
By phase
- Not applicable5,354
- Phase 2609
- Phase 1563
- Phase 3420
- Phase 4318
- Phase 1/Phase 2290
- Phase 2/Phase 386
Top conditions
- Obesity617
- Ovarian Cancer337
- Pancreatic Cancer290
- Type 2 Diabetes277
- Diabetes191
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2172
- Hypertension138
- Type 1 Diabetes132
- Metabolic Syndrome128
- Obesity & Overweight125
- Breast Cancer112
- Overweight105
- Cardiovascular Diseases104
- Amyotrophic Lateral Sclerosis101
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer89
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California524
- Maryland178
- Alabama175
- Arizona171
- Florida164
- Texas159
- Massachusetts151
- New York143
- Colorado115
- Pennsylvania114
Recruiting studies7,640 total
- NCT02417740Recruiting
Study of the natural course of noncirrhotic portal hypertension
This study follows people with noncirrhotic portal hypertension (NCPH) or people at risk for it to better understand how the condition progresses over time. It does not sound like a medication trial—more like careful monitoring to learn what happens in different people.
Bethesda, MarylandAges 12–100 - NCT02646475RecruitingPhase 1
Study angiotensin medicine to improve metabolism in obesity
This Phase 1 study tests how a medication that affects the body’s angiotensin system (angiotensin-(1-7)) changes metabolism in adults with obesity, insulin resistance, and high blood pressure. It may help researchers understand whether this approach can improve blood sugar/insulin function and related body changes.
Nashville, TennesseeAges 18–60 - NCT02202681Enrolling by invitation
Swallowable capsule scans the duodenum with special imaging
This study tests whether a swallowable imaging capsule can safely look at the duodenum (the first part of the small intestine). It may help researchers better understand gut lining changes, such as those seen in celiac disease.
Boston, MassachusettsAges 16 years+ - NCT02669797Enrolling by invitation
Family-based program to help families eat dinner together
This study offers an intervention focused on family dinners to help children improve their eating habits. It targets children who eat family dinners rarely and have a higher weight range, to see if the program can help improve health over time.
Aurora, ColoradoAges 5–10 - NCT02609685Recruiting
Active monitoring for tiny papillary thyroid cancer
This study looks at whether closely watching (without immediate surgery or treatment) a very small thyroid cancer can be safe. You may benefit by avoiding unnecessary procedures, while the team monitors your thyroid and any changes over time.
Los Angeles, CaliforniaAges 18 years+ - NCT02497534Recruiting
Biomarker testing study for Friedreich’s ataxia
This study looks at “biomarkers” (measurable signs in the body, like test results from blood or other checks) in people with Friedreich’s ataxia. It may help researchers understand the disease better and track changes over time.
Gainesville, FloridaAges 6–70 - NCT02393703Recruiting
Testing blood signals from tiny cell packets in pancreatic surgery
This study looks at how tiny particles in blood (“exosomes”) carry signals between cells in people having pancreatic surgery. The goal is to understand these signals in different pancreatic conditions and treatment situations, which may help future care.
New York, New YorkAges 18 years+ - NCT02237625Recruiting
Study tracking patients with hypophosphatasia over time
This study follows people who already have hypophosphatasia (HPP) to better understand how the condition changes over time. It may help doctors recognize patterns and improve care, even if you are not receiving a new treatment.
Durham, North CarolinaAges Any age - NCT02437396Recruiting
Blood tests in stable adults with Gaucher disease
This study measures inflammation and “oxidative stress” (cell stress caused by imbalance in the body) using blood biomarkers in adults with Gaucher disease. It may help researchers understand what’s happening in the body and how treatment status relates to these blood signals.
Minneapolis, MinnesotaAges 18–75 - NCT02579044Enrolling by invitationPhase 1/Phase 2
Everolimus plus lonafarnib for children with progeria
This trial tests whether adding everolimus to ongoing lonafarnib improves health and slows complications in people with genetically confirmed progeria. It mainly checks safety and early signs of benefit in Phase I/II.
Boston, MassachusettsAges 1.5 years–25 years - NCT02193295Recruiting
Testing how changing fats affects insulin resistance
This study tests how “lipid” (fat) changes in the body affect insulin resistance, which is when the body doesn’t respond to insulin as well as it should. Because it’s done in healthy people, it’s mainly looking at basic biology and may help guide future treatments.
New Haven, ConnecticutAges 18–90 - NCT02650622Recruiting
Study of genetic and metabolic diseases in children
This study looks at children who may have genetic (inherited) or metabolic (body chemistry) problems, including newborn screening and episodes of trouble. The goal is to better understand these conditions and identify children who may benefit from further care.
Dallas, TexasAges 1 day+ - NCT02310178Recruiting
Long-term follow-up after bariatric surgery at Montpellier
This study follows people who have had weight-loss surgery at Montpellier University Hospital to see how they do over time. It helps doctors understand the long-term benefits and challenges after surgery.
MontpellierAges 15 years+ - NCT02435940Recruiting
Registry for inherited eye vision conditions
This study is a registry, meaning it collects information about people with inherited retinal (retina) diseases. It may help researchers learn how these conditions progress and connect you with future studies or treatments.
Columbia, MarylandAges Any age - NCT02356653RecruitingEarly Phase 1
Stem cell transplant help for children lacking a matching sibling
This expanded-access study offers a specific type of stem cell transplant preparation that removes certain immune cells (CD3 and CD19) from donor stem cells. It is for children who need a transplant but do not have a fully matched sibling donor and whose team cannot use the hospital’s usual matching device protocol.
Philadelphia, PennsylvaniaAges Up to 30 years - NCT02235623Recruiting
Testing a specific surgery for an undescended testicle
This trial studies a surgery approach (Fowler-Stephens orchiopexy) for boys whose testicle is found higher in the abdomen during a camera procedure. It may help doctors choose the best technique to move the testicle into the scrotum.
Boston, MassachusettsAges 4 months–3 years - NCT02333604Recruiting
Cancer experience registry for patients and caregivers
This registry collects information about the experiences of people with cancer and the people who care for them. Joining could help researchers better understand needs and improve support, without requiring cancer treatment changes.
Washington D.C., District of ColumbiaAges 18 years+ - NCT02302742Recruiting
Registry for triple-negative breast cancer and inherited mutation carriers
This registry studies people with triple-negative breast cancer or inherited “HBOC” gene mutations (like BRCA, PALB2, PTEN, TP53). It collects information to better understand risk, outcomes, and how these cancers behave—helping future research and care.
Hays, KansasAges Any age - NCT02478892Recruiting
Screening study for pancreatic cancer in inherited gene risk
This trial tests ways to screen people who have a family-passed (inherited) gene mutation linked to higher pancreatic cancer risk. The goal is to find pancreatic cancer earlier and improve how screening is done for people at increased risk.
Philadelphia, PennsylvaniaAges 18 years+ - NCT02254863RecruitingPhase 1
Stem cell transplant into the spinal fluid for rare brain diseases
This Phase 1 trial tests a transplant using special donated stem-cell–like cells placed into the spinal fluid to treat certain inherited brain diseases. It is mainly designed to check safety, and it may offer benefit by targeting brain and nerve damage.
Durham, North CarolinaAges 1 week–22 years - NCT02361320Recruiting
CT scan study for pancreatic or liver bile cancer
This study looks at how CT scans (detailed X-ray pictures) help diagnose pancreatic cancer or hepatobiliary (liver/bile duct) cancers. It may help your care team better decide what’s going on and plan next treatments.
Houston, TexasAges 18 years+ - NCT02316314Recruiting
Study heart scan and function in people with Friedreich’s ataxia
This study uses heart tests (including ultrasound and MRI) to better understand how Friedreich’s ataxia affects the heart. You might benefit by getting detailed heart evaluation and contributing to research that could guide future care.
New York, New YorkAges 12–50 - NCT02306720Enrolling by invitation
Patient registry for hypophosphatasia (HPP)
This trial is a registry that collects information about people with hypophosphatasia to help researchers understand the condition better. It may help future studies, but it’s not a treatment trial.
Centennial, ColoradoAges Any age - NCT02469662Recruiting
Study of outcomes after Nexel total elbow replacement
This study looks at how well the Nexel total elbow replacement works over time for people who need an elbow replacement due to pain, damage, or instability. It may help the doctors understand which patients benefit most and what results to expect.
Golden, ColoradoAges 18 years+
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,640 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 12,087 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.