Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,607 recruiting studies in this area right now.
By phase
- Not applicable5,335
- Phase 2607
- Phase 1557
- Phase 3417
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 385
Top conditions
- Obesity619
- Ovarian Cancer336
- Pancreatic Cancer289
- Type 2 Diabetes276
- Diabetes192
- Diabetes Mellitus183
- Diabetes Mellitus, Type 2170
- Hypertension138
- Type 1 Diabetes130
- Metabolic Syndrome126
- Obesity & Overweight123
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Colorectal Cancer92
- Pancreas Cancer90
- Endometrial Cancer87
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center41
- Massachusetts General Hospital41
- Eli Lilly and Company40
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland180
- Alabama176
- Arizona170
- Florida166
- Texas158
- Massachusetts151
- New York142
- Colorado115
- Pennsylvania113
Recruiting studies7,607 total
- NCT07777575RecruitingPhase 4
Exercise and medication for weight loss while preserving muscle
This study tests whether a type 2 diabetes medication (tirzepatide) combined with a supervised resistance training (weight lifting) program helps prevent muscle loss while losing weight. You will either receive the medication or a placebo, and all participants will follow a diet and exercise plan.
München, BavariaAges 18–60 - NCT07780513Recruiting
Genetics of muscle insulin resistance study
This study looks at how genes affect the way muscles use sugar, which can help understand insulin resistance. Participants will have tests and procedures, including a glucose drink test and a muscle biopsy, to see how their bodies handle sugar.
San Antonio, TexasAges 18–75 - NCT07779200Recruiting
Bicarbonate dialysis for kidney failure patients
This study tests a type of dialysis that uses different levels of bicarbonate to see if it can improve health for people with kidney failure. It may help patients who are already on regular dialysis.
Stevenage, HertfordshireAges 18 years+ - NCT00286637Recruiting
New tests to diagnose glaucoma and related eye problems
This study tests new ways to diagnose glaucoma (and sometimes related eye conditions) using eye exams and measurements. It may help improve how doctors detect glaucoma earlier and more accurately.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05937789Recruiting
Vitamin D3 during early ICU care to help critically ill adults
This trial tests whether starting vitamin D3 soon after ICU admission helps critically ill adults with low vitamin D levels. It may help correct low vitamin D and possibly improve recovery, depending on your health situation.
TaipeiAges 18 years+ - NCT06265246Recruiting
Milk and yogurt for stronger bones in young adults
This study tests whether adding milk and yogurt to your diet can improve bone health and body composition. If you're a young adult with low calcium intake, you may qualify to join.
Saskatoon, SaskatchewanAges 19–30 - NCT06198400Recruiting
Dye test for blood flow after pancreas surgery
This trial uses a special dye to check blood flow in the remaining part of your pancreas after surgery. It helps doctors see if the tissue is getting enough blood, which can improve healing and reduce complications.
Prague, Czech RepublicAges 18 years+ - NCT06556342Recruiting
Testing a new contrast agent for ovarian mass ultrasound
This trial is testing an investigational contrast agent (FRD001) to see if it improves ultrasound images of suspicious ovarian masses. The goal is to help doctors better tell if a mass is cancerous or not.
Wuhan, HubeiAges 18–75 - NCT06426290Recruiting
Predicting success after weight-loss surgery
This study looks at whether a psychological test can help predict who will do well after weight-loss surgery. Researchers are reviewing past test results and surgery outcomes to find patterns.
MoulinsAges 18 years+ - NCT06560983Recruiting
Blood sugar and stroke outcomes over one year
This study watches how blood sugar levels affect recovery and risks over one year in people who come to the ER with a stroke. It aims to help doctors better manage blood sugar during emergency stroke care.
Kathmandu, BagmatiAges 18 years+ - NCT05120492Recruiting
Program for severe knee arthritis and extreme weight
This feasibility study tests a practical approach to help people with very severe knee arthritis and very high body weight. It aims to find an effective and safe way to manage both conditions together in real-world care.
Halifax, Nova ScotiaAges 18–65 - NCT05658289Recruiting
Latarjet vs shoulder bone surgery after front dislocation
This trial compares two types of surgery that rebuild the front (anterior) shoulder bone when there has been significant bone loss. It may help find which operation works better to keep your shoulder from dislocating again.
Halifax, Nova ScotiaAges 16–40 - NCT07774949Recruiting
Thyroid and anxiety effects on baby heart rate in high-risk pregnancy
This study looks at how thyroid function and anxiety in mothers might affect the baby's heart rate patterns (shown on a non-stress test) in high-risk pregnancies. The goal is to help doctors better understand and support high-risk pregnancies.
IstanbulAges 18–45 - NCT06544473RecruitingPhase 4
Estrogen pill vs. patch for Turner syndrome
This trial compares oral and transdermal (patch) estrogen to find the right dose for women with Turner syndrome. It aims to see which method works best for hormone replacement.
Aarhus, Aarhus NAges 18–50 - NCT06563687Recruiting
Continuous glucose monitoring for HIE newborns
This study tests a continuous glucose monitor (CGM) in newborns with hypoxic-ischemic encephalopathy (HIE) — a type of brain injury from lack of oxygen around birth. The CGM tracks sugar levels to help doctors manage care better.
AvellinoAges Up to 6 hours - NCT07773246RecruitingPhase 1/Phase 2
Study of KRRO-121 in healthy adults and people with urea cycle disorder
This study tests an investigational drug called KRRO-121. It is first tested in healthy volunteers to check safety, and then in patients with urea cycle disorder (a condition where the body can't remove ammonia properly) to see if it helps.
Melbourne, VictoriaAges 18–65 - NCT07775391RecruitingPhase 1/Phase 2
Stem cell infusion for early menopause
This trial tests whether a single infusion of stem cells made from human umbilical cord tissue can help women with premature ovarian insufficiency (early menopause) by improving ovarian function and reducing menopause symptoms. Participants will continue their usual hormone replacement therapy during the study.
Beijing, Beijing MunicipalityAges 18–40 - NCT07767175RecruitingPhase 1
Weight loss study for adults with overweight or obesity
This study tests an investigational medication, called NNC0721-8060, to see how it works in people with excess weight (overweight or obesity). It may help with weight loss, but is still in early human testing.
Lenexa, KansasAges 18–55 - NCT07770841RecruitingPhase 3
Oral medication for weight loss study
This study tests an oral medicine (semaglutide) to see if it helps adults with excess weight lose weight. It might offer an easier, pill-based treatment option for weight management.
Birmingham, AlabamaAges 18 years+ - NCT07775404RecruitingPhase 3
Weight loss medication for Asian adults with obesity or overweight
This study tests an investigational medication called elecoglipron for weight loss in Asian adults who are overweight or have obesity, with or without type 2 diabetes. It may help participants lose weight and improve health.
BaotouAges 18 years+ - NCT07768813RecruitingPhase 1
Comparing two versions of an injected drug in healthy and overweight people
This trial compares two different versions of an injected study drug (survodutide) to see how they are absorbed by the body. It is open to healthy people and people with overweight or obesity, and it may help researchers find a better way to deliver this treatment.
MannheimAges 18–55 - NCT04014413Recruiting
Fecal transplant for gut and immune-related conditions
This trial studies whether fecal microbiota transplantation (FMT)—a medical procedure using stool from a screened donor to restore gut bacteria—can improve safety and outcomes for people with certain bowel, immune, and metabolic conditions. It may help if your symptoms are thought to be related to an unhealthy gut microbiome, though eligibility is broad and depends on specific safety factors.
Hong Kong, ShatinAges Any age - NCT07774065Recruiting
Ventilation strategies in obese patients during laparoscopic surgery
This study tests different ways of using a breathing machine (ventilator) during laparoscopic surgery in people with obesity. The goal is to find a safer and more effective ventilation method for this group.
Galveston, TexasAges 18 years+ - NCT07773272Recruiting
Combined heart, kidney, and metabolic care after a heart attack
This study tests a new approach to managing heart, kidney, and metabolic health together after a heart attack or unstable angina. It aims to improve your recovery and reduce future risks.
Heerlen, LimburgAges 18 years+
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,607 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,814 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.